Digital Commons Network^™

Abnormal Response Of Tumor Vasculature To Vasoactive Drugs, Rosanna C. Chan, Charles F. Babbs, Richard J. Vetter, Carlton H. Lamar

Weldon School of Biomedical Engineering Faculty Publications

The effects of the vasoconstrictor, phenylephrine, and the vasodilator, hydralazine, on blood flow to tumor were studied and compared to those on blood flow to normal tissues in vivo. Regional blood flow and cardiac output were measured with the use of radioactive microspheres in 150- to 250 g inbred Harlan F344 rats bearing subcutaneous nodules of two types of transplantable carcinoma ("hard" and "soft") with microscopically different vascular patterns. Three groups of rats were treated with hydralazine, saline, or phenylephrine, and regional blood flow was determined at the time of maximum blood pressure response. Results were correlated with quantitative morphometric …

Cardiac, Thoracic, And Abdominal Pump Mechanisms In Cardiopulmonary Resuscitation: Studies In An Electrical Model Of The Circulation, Charles F. Babbs, Christopher Weaver, Sandra H. Ralston, Leslie A. Geddes

Weldon School of Biomedical Engineering Faculty Publications

To investigate alternative mechanisms generating artificial circulation during cardiopulmonary resuscitation (CPR), an electrical model of the circulation was developed. Heart and blood vessels were modeled as resistive-capacitive networks; pressures in the chest, abdomen, and vascular compartments as voltages; blood flow as electric current; blood inertia as inductance; and the cardiac and venous valves as diodes. External pressurization of thoracic and abdominal vessels, as would occur in CPR, was simulated by application of half-sinusoidal voltage pulses. Three modes of creating artificial circulation were studied: cardiac pump (CP), in which the atria and ventricles of the model were pressurized simultaneously; thoracic pump …

Intrapulmonary Epinephrine During Prolonged Cardipulmonary Resuscitation: Improved Regional Blood Flow And Resuscitation In Dogs, Sandra H. Ralston, William D. Voorhees, Charles F. Babbs

Weldon School of Biomedical Engineering Faculty Publications

Blood flow to vital organs was measured at five-minute intervals during 20 minutes of cardiopulmonary resuscitation (CPR) and ventricular fibrillation in two groups of anesthetized dogs (n = 15 per group). The relationship between organ blood flow and restoration of circulation after 20 minutes was assessed with no additional treatment in Group I and with intrapulmonary epinephrine in Group II. Cardiac output and organ blood flow did not vary significantly in Group I. In Group II, intrapulmonary epinephrine significantly improved blood flow to the myocardium, the brain, and the adrenal glands. A mean myocardial blood flow of less than 0.13 …

Theoretical Advantages Of Abdominal Counterpulsation In Cpr As Demonstrated In A Simple Electrical Model Of The Circulation, Charles F. Babbs, Sandra H. Ralston, Leslie A. Geddes

Weldon School of Biomedical Engineering Faculty Publications

Animal studies and preliminary clinical observations suggest that the addition of interposed abdominal compressions (IAC) to ventilation and chest compression of standard cardiopulmonary resuscitation (CPR) augments blood flow, blood pressures, and immediate survival. To investigate the physical basis for enhanced circulation during IAC-CPR, we developed an electrical model of the circulation. Heart and blood vessels were modeled as resistive-capacitive networks, pressures as voltages, blood flow as electric current, blood inertia as inductance, and the cardiac and venous valves as diodes. External pressurization of the heart and great vessels, as would occur in CPR, was simulated by application by half-sinusoidal voltage …

Efficacy And Safety Of The Reciprocal Pulse Defibrillator Current Waveform, M J. Niebauer, Charles F. Babbs, L A. Geddes, J D. Bourland

Weldon School of Biomedical Engineering Faculty Publications

The efficacy and safety of a new defibrillating current waveform, consisting of a low-tilt 5 ms trapezoidal pulse followed closely by a second identical pulse of opposite polarity, was tested m seven isolated, perfused, working canine hearts suspended in an isoresistive, isosmotic shock bath at 37 oC. The efficacy and safety of the reciprocal pulse was compared with a single 5 ms pulse, a single 10 ms pulse, and a dual (unidirectional) 5 ms pulse waveform. The mean threshold average current densities for the 5 ms single pulse, 10 ms single pulse, dual 5 ms pulse, and reciprocal pulse (absolute …

Fuel Ethanol From Raw Corn, Curtis Weller, M. P. Steinberg, E. D. Rodda

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Crude amylase preparations were produced by growing Aspergillus awamori and A. niger on raw, ground, whole corn. These Koji preparations were used to hydrolyze the starch of raw, ground whole corn to sugars during simultaneous fermentation of the sugars to ethanol by distillers active dry yeast. Ethanol concentrations of the fermentation beers were determined with gas-chromatography. These fermentations yielded an average of 89.6% theoretical ethanol compared to control, conventional, fermentations that had an average of 89.9%. Carbon dioxide evolutions were determined with use of Alwood valves. The initial fermentation rate was greater for the conventional fermentation than the Koji fermentation. …

Human Health Effects Assays, Ronald C. Sims, J. L. Sims, R. R. Dupont

Biological Engineering Faculty Publications

Current development and use of short-term bioassays to evaluate potential human health hazards of environmental chemical exposure has been the focus of the U. S. Environmental Protection Agency (EPA) Second and Third Symposia on the Ap plication of Short-Term Bioassays in the Analysis of Complex Environmental Mixtures.¹'² Topics addressed included development and applications of bioassays, collection and preparation of environmental samples, characterization of hazardous components using bioassays, and environmental assessment. Bartsch and Tomabis,³ using six mutagenicity assays including sub mammalian and mammalian assays to evaluate the quantitative relationship between carcinogenicity and mutagenicity for 532 chemicals, concluded …

Bulletin Ma 20 - Sheep Yard Plans - Flocks Up To 500, D. Bicknell

Animal production and livestock published reports

Manjimup Regional Office

Owners of small flocks often use much more labour per sheep than do owners of large flocks. Most of the difference in labour use is the design of sheep sheds and sheep yards, and a smaller affect from the mob size and experience in handling sheep.

This booklet gives some detail on design and construction of yards and a number of yard plans to handle up to 500 or so sheep. Many of the plans are from an Australian Wool Corporation publicatiot1 "Wool Harvesting Notes".

Preparation And Characterization Of Blocked Diisocyanate Monomers For Dental Applications, Stephen Richard Angeli

Theses

Six new monomers were prepared and characterized. The six monomers are blocked diisocyanate compounds. In the preparation 2,4-tolylene diisocyanate was first blocked with 2=hydroxyethyl methacrylate in the para NCO position. Six different blocking agents were then used to block the ortho NCO in the preparation of the monomers: (1) p-methoxyphenol, (2) m-methoxyphenol, (3) o-methoxyphenol, (4) p-chlorophenol, (5) m-chlorophenol, and (6) o-chlorophenol. The six monomers were characterized by mp, liquid chromatography, IR, NMR, and elemental analysis. All the characterizations show that the monomers are indeed the desired products.

Interactive Computer Aided Design And Animation Of Spatial Mechanisms, Emmet B. Peter

Retrospective Theses and Dissertations

The synthesis of planar and spatial mechanisms is often accomplished by either trial and error supplemented by computer analysis or by specific analytical techniques in the literature. In either case it is extremely helpful to be able to visualize a physical design as it emerges, and to see a graphic display of it in animated motion. This paper describes the development of a general interactive program for both analyzing and viewing a spatial 4-bar (RSSR) mechanism in animated motion. The analysis provides complete position, velocity, and acceleration information and, for the special case of the planar 4-bar, the same information …

Treatment Process Optimization At The Lee Hall Water Treatment Plant Newport News, Virginia, Marcy Granum Garnett

Civil & Environmental Engineering Theses & Dissertations

Various methods can be used in operating a water treatment plant. It is desirable to produce good quality water as efficiently and economically as possible. This study evaluates each phase of operation at the Newport News (Lee Hall} water treatment plant for overall efficiency.

This study begins by giving a detailed description of the Lee Hall water treatment plant. The description includes sources of water, a description of each treatment process, a plan view of the treatment plant, and a flow diagram of the treatment plant.

Based on the raw water data, flow rates, and the treatment plant characteristics, the …

The Geology Of Maine's Coastline : A Handbook For Resource Planners, Developers, And Managers, Maine State Planning Office

Maine Collection

The Geology of Maine's Coastline : A Handbook for Resource Planners, Developers, and Managers

Executive Department, Maine State Planning Office, Augusta, Maine, June 1983.

Contents: List of Figures / Introduction: The Geological Connection / Chapter 1: Using the Marine Environments Maps / Chapter 2: Perspectives of the Maine Coast / Chapter 3: The Building Blocks of Maine's Coast / Chapter 4: The Disappearing Shoreline / Where to Go for Help / Some Planning Considerations for Development in Coastal Geologic Environments / Land Use Laws of Special Interest to Individual Coastal Property Owners

The Effect Of Ultrasound On The Hydrolysis Of Carbohydrates, Adel A. Khamis

Dissertations

Acid hydrolysis of dextran and cellulose were studied with and without irradiation with ultrasonic waves of different frequencies (17 - 150 KHz), and powers (0.4 - 200 w/cm²). In the case of both materials, the hydrolysis reaction was found to be first order with respect to the activity of hydrogen ions in the reaction medium. Weight average molecular weight was evaluated at different durations of the reaction course. The reaction rate of dextran was found to be proportional to the weight average molecular weight raised to the power 4/3, and raised to the power 4 for cellulose.

The …

An Experimental System For Observation Of The Rat Coronary Microcirculation Using Digital Image Processing, Wolfgang Braun

Theses

A system was constructed which allows direct observation of the coronary microcirculation of the beating rat heart. An EKG triggered strobe is used on the microscope light source to "stop" the action of the beating heart so the surface microvessels can be observed di rectly under the microscope. Experimental results are recorded on videotape and played back for frame-by-frame analysis of the data using digital Image processing techniques such as digital filtering, image extraction, image enhancement and edge detection.

The application of image enhancement techniques (high order and low order enhancement methods ) as well as edge detection using a …

Managing In The Technical Sales Arena, Robert Munro

Theses

The major objective of this thesis is to portray the role of a Field Engineer for a major manufacturer of electrical distribution and control equipment. In so doing, it should represent a reasonable facsimile of what a sales manager of a large Field Office, comprised of approximately twelve Field Engineers, would encounter in his supervisory capacity. As such, it should provide information for those interested in entering and hoping to manage in technical sales career.

While much of the information was derived from books, periodicals, and conversations with people associated with the electrical industry, the major portion of the work …

Automated Instrumentation System For Studies Of Metabolic Rates In Rats, Suhas P. Pathak

Theses

The task of the instrumentation system is to measure the respiratory exchange in rats in a controlled experiment. Air is drawn at a predeter-mined rate in and out of rat chambers. The proportion of oxygen and carbon dioxide in the ensuing air indicates the respiratory rate of the rat. The entire operation is controlled by a microcomputer whose most important functions are: to direct the flow of air through the rat chambers by switching valves; and to collect data about the percentages of gases in question.

Thus with the help of a computer it is possible to monitor and control …

Evaluating The Design And Operation Of Irrigation Canals In Egypt, Amany El Kayal

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

A computer simulation model for temperature data was developed in order to generate synthetic daily temperature. The model consists of two components: a deterministic component represented by a Fourier series fit, and a stochastic component represented by an autoregressive model. The simulation model was proven to be able to preserve the main statistics of the historical series.

The data generated by the above temperature model were used as an input to an irrigation water requirements simulation model. This model incorporates the probabilistic nature of these requirements. The irrigation system of Abo Raya area in Egypt was used to demonstrate the …

An Update On College And University Programs In Air Pollution Control, Harold M. Cota

Civil and Environmental Engineering

A survey of academic programs in air pollution control was made. Results from the 127 schools reporting are tabulated by state. Faculty involved in air pollution instruction are identified. Some conclusions and recommendations are presented.

Motivation And The First Line Supervisor: A Survey Of Techniques And Applications, Raymond H. Rannfeldt

Graduate Research Papers

Do first line supervisors differ in their beliefs concerning motivation or in the techniques they employ to motivate their personnel as a function of age, time in service with a company and/or time as a supervisor?

Plan Of Study For Cross Florida Barge Canal: Economic Analysis, United States. Army. Corps Of Engineers. Jacksonville District

Correspondence and Textual Material

At the time of the previous study of transportation savings, commerce in coal primarily for electric power generation could not be ·projected with any degree of accuracy because most electric utilities had not developed firm plans for building new coal-fired plants· or for converting from petroleum products or natural gas to coal at existing plants. Today, with plants already constructed that will burn coal, there is a greater probability of defining coal needs. So there is a need to reevaluate potential coal traffic via the CFBC. Also there is a need to evaluate the other types of benefits mentioned under …

Traffic Safety Analysis: University Of Kentucky Area, Kentucky Transportation Research Program

Kentucky Transportation Center Research Report

The concept of Transportation System Management (TSM) is based on the use of transportation facilities for the efficient and safe movement of people and goods. Through a grant administered by the U.S. Department of Transportation, the Lexington-Fayette Urban County Government contracted with the University of Kentucky (UK) to develop and implement a "Ridesharing Program" and a "Minor Traffic Control Improvements Program".

Discussions of the traffic safety problems around the University area by the Lexington-Fayette Urban County Council coincided with UK's initial work in the traffic safety portion of the grant. Following those discussions, a request was made by the Council …

The Effects Of Limited Food Availability On The Striped Bass Fishery In Lake Mead, John R. Baker, Larry J. Paulson

Publications (WR)

The original range of striped bass (Morone saxatilis) was along the Atlantic Coast. They were introduced into the lower Sacramento River in 1879 and are now also found along the Pacific Coast. A landlocked striped bass fishery was established in Santee-Cooper Reservoir, South Carolina, in 1954, and they have since been introduced into numerous other reservoirs, including Lake Havasu, Lake Mead and Lake Powell on the Colorado River. Striped bass were introduced into Lake Mead in 1969 in response to declines in the largemouth bass (Micropterus salmoides) fishery that occurred during the 1960s and in order to further utilize the …

Saving Energy In Rural Maine : Or Who's Doing What On The Farm, Mane Department Of Agriculture

Maine Collection

Saving Energy In Rural Maine : Or Who's Doing What on the Farm

Compiled by Bettina M. Blanchard and Edited by Bill Seekins.

Maine Department of Agriculture, Food and Rural Resources, Division of Resources Development, Augusta, Maine, 1983.

Contents: List of Photographs and Diagrams / Introduction / Projects / 1. Wind / 2. Wood Heat Applications On the Farm / 3. Solar Applications / 4. Manure Handling and Waste Utilization / 5. Energy Efficient Cooling Methods / 6. Energy Saving In Field Operations / 7. Production and Use of Alternative Fuels / 8. Multi-Project Sites / Summary and Conclusions / …

Granular Activated Carbon Pilot Plant For The Removal Of Color, Toc, And Thmfp, Jeffrey L. Herr

Retrospective Theses and Dissertations

As part of an Environmental Protection Agency grant to reduce the trihalomethane concentration in the Melbourne, Florida drinking water, a granular activated carbon (GAC) plant was operated for approximately 1 year. Four GAC pilot plant systems were operated in parallel each treating a different influent. Raw water, coagulated, settled and filtered water, filtered water with ozone pretreatment, and filtered water with chlorine dioxide pretreatment were pumped through the individual systems. Influent and effluent concentrations of various pollutants were monitored regularly throughout the study. The raw water GAC system showed rapid breakthrough for color, total organic carbon (TOC) and trihalomethanes (THM's). …

Limiting Swine Stress With Evaporative Cooling In The Southeast, Robert L. Fehr, K. T. Priddy, Samuel G. Mcneill, Douglas G. Overhults

Biosystems and Agricultural Engineering Faculty Publications

Three-hourly weather data for 7 locations in the Southeast and Central United States were used to evaluate the feasibility of evaporative cooling for reducing swine stress. Stress was defined as a relationship between dry and wet bulb temperatures which exceeded a stress index of 85. This analysis indicates that properly installed evaporative coolers could reduce the number of hours that stress would occur in swine facilities from 89.6 to 96.4% depending on location.

A Dairy Cow Housing System Featuring Motel Free Stalls, Robert L. Fehr, William L. Crist

Agricultural Engineering Extension Updates

The term motel free stalls describes a milking cow housing system that utilizes roof area which protects only the free stalls. Alleys are only partially protected by the roof overhang. This system provides little protection from extreme temperatures but can provide some summer protection if properly constructed. Motel free stall systems reduce the initial cost of constructing lactating cow housing. Motel free stall system described in this paper should be used with caution in climatic regions colder than Kentucky because of limited protection from extreme cold temperatures. This paper describes the application of motel free stall housing systems and a …

An Experimental Investigation Of The Effects Of Crude Oil On Two Freshwater Lake Ecosystems, Martin D. Werner, V. Dean Adams, Vincent A. Lamarra

Reports

Responses of two freshwater lake ecosystems of the Intermountain West to crude oil impaction were investigated. The research was conducted in two phases; in the first phase effects of crude oil were studied on an ecosystem established in three phase laboratory microcosms (gaseous-aqueous-sediment), which simulated the natural lakes. Notable responses of the microcosm ecosystem to oil impaction included: an increased oxygen demand by the biological community, nutrient immobilization, a reduction in plant biomass accumulation and a heterotrophically dominated ecosystem. The increased availability of biologically degradable reduced carbon (i.e., the oil) and nutrient immobilization, rather than toxic effects of oil on …

Effects Of Cadmium On Streams And Irrigated Agriculture In The Presence And Absence Of Oil Shale Leachate, Douglas A. Selby, Jean M. Ihnat, Fredrick J. Post, Jay J. Messer

Reports

Artificial streams, soil perfusion columns, and potted plants were exposed to 20 ug Cd/l in the presence and absence of unretorted oil shale leachate. High cadmium accumulations occurred in the stream biota, but did not measurably affect community structure or function. The presence of oil shale leachate had no effect on bioaccumulation or ecosystem structure or function. Nitrification in soil columns was enhanced by the presence of the organic fraction of oil shale leachate, but this effect was not observed when cadmium was present. Crop accumulation of cadmium was somewhat higher in alfalfa and radishes irrigated with leachate, but did …

Polycyclic Aromatic Hydrocarbons: Are They A Problem In Processed Oil Shales?, David L. Maase, V. Dean Adams

Reports

Organic residues from processed oil shales were characterisized with specific attention to polycyclic aromatic hydrocarbons (PAH). Oil shale development in the White River Basin (Utah and Colorado) was projected and hydrological and geological parameters pertinent to estimations of polycyclic aromatic hydrocarbons (PAH) flux were focused. Oil shale samples from the Union B, Paraho, and Tosco II processes were extracted by using organic solvents in a soxhlet apparatus and by mixing shale samples with water (characterization in

Fecal Coliform Release Studies And Development Of A Preliminary Nonpoint Source Transport Model For Indicator Bacteria, Everett P. Springer, Gerald F. Gifford, Michael P. Windham, Richard Thelin, Michael Kress

Reports

The effect of grazing on water quality has been documented by bacteriological studies of streams adjacent to grazed areas. Bacterial release from fecal deposits is a parameter of the pollution transport mechanism that is poorly understood. The objective of this study was to determine a fecal coliform release function for cattle fecal deposits. Standard cowpies were rained on with a rainfall simulator, and the fecal coliform counts were determined using the most probably number (MPN) method of enumeration. The fecal deposits were rained on at ages 2 through 100 days. The effects of rainfall intensity and recurrent rainfall were tested. …