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A Machine Learning Approach To Post-Market Surveillance Of Medical Devices, Jonathan Bates, Shu-Xia Li, Craig Parzynski, Ronald Coifman, Harlan Krumholz, Joseph Ross 2015 Yale University

A Machine Learning Approach To Post-Market Surveillance Of Medical Devices, Jonathan Bates, Shu-Xia Li, Craig Parzynski, Ronald Coifman, Harlan Krumholz, Joseph Ross

Yale Day of Data

Post-market surveillance is a collection of processes and activities used by product manufacturers and regulators, such as the U.S. Food and Drug Administration (FDA) to monitor the safety and effectiveness of medical devices once they are available for use “on the market”. These activities are designed to generate information to identify poorly performing devices and other safety problems, accurately characterize real-world device performance and clinical outcomes, and facilitate the development of new devices, or new uses for existing devices. Typically, a device is monitored by comparing adverse events in the exposed population to a matched unexposed population. This research considers …


Grabbing The Air Force By The Tail: Applying Strategic Cost Analytics To Understand And Manage Indirect Cost Behavior, Bradley C. Boehmke 2015 Air Force Institute of Technology

Grabbing The Air Force By The Tail: Applying Strategic Cost Analytics To Understand And Manage Indirect Cost Behavior, Bradley C. Boehmke

Theses and Dissertations

Recent and projected reductions in defense spending are forcing the military services to develop systematic approaches to identify cost reduction opportunities and better manage financial resources. In response, the Air Force along with her sister services are developing strategic approaches to reduce front-line mission resources, commonly referred to as the Tooth . However, an underemphasized contributing source of costs are mission support activities, commonly referred to as the Tail . With the tail historically representing a sizable portion of the annual Air Force budget, strategically managing cost behavior of these indirect activities has the opportunity to generate significant cost reductions. …


Integrated Systems Health Management As An Enabler For Condition Based Maintenance And Autonomic Logistics, Robert M. Vandawalker 2015 Air Force Institute of Technology

Integrated Systems Health Management As An Enabler For Condition Based Maintenance And Autonomic Logistics, Robert M. Vandawalker

Theses and Dissertations

Health monitoring systems have demonstrated the ability to detect potential failures in components and predict how long until a critical failure is likely to occur. Implementing these systems on fielded structures, aircraft, or other vehicles is often a struggle to prove cost savings or operational improvements beyond improved safety. A system architecture to identify how the health monitoring systems are integrated into fielded aircraft is developed to assess cost, operations, maintenance, and logistics trade-spaces. The efficiency of a health monitoring system is examined for impacts to the operation of a squadron of cargo aircraft revealing sensitivity to and tolerance for …


Reliable Power System Planning And Operations Through Robust Optimization, Wei Yuan 2015 University of South Florida

Reliable Power System Planning And Operations Through Robust Optimization, Wei Yuan

USF Tampa Graduate Theses and Dissertations

In this dissertation, we introduce and study robust optimization models and decomposition algorithms in order to deal with the uncertainties such as terrorist attacks, natural disasters, and uncertain demand that are becoming more and more signicant in power systems operation and planning. An optimal power grid hardening problem is presented as a defender-attacker-defender (DAD) sequential game and solved by an exact decomposition algorithm. Network topology control, which is an eective corrective measure in power systems, is then incorporated into the defender-attacker-defender model as a recourse operation for the power system operator after a terrorist attack. Computational results validate the cost-eectiveness …


Spatiotemporal Sensing And Informatics For Complex Systems Monitoring, Fault Identification And Root Cause Diagnostics, Gang Liu 2015 University of South Florida

Spatiotemporal Sensing And Informatics For Complex Systems Monitoring, Fault Identification And Root Cause Diagnostics, Gang Liu

USF Tampa Graduate Theses and Dissertations

In order to cope with system complexity and dynamic environments, modern industries are investing in a variety of sensor networks and data acquisition systems to increase information visibility. Multi-sensor systems bring the proliferation of high-dimensional functional Big Data that capture rich information on the evolving dynamics of natural and engineered processes. With spatially and temporally dense data readily available, there is an urgent need to develop advanced methodologies and associated tools that will enable and assist (i) the handling of the big data communicated by the contemporary complex systems, (ii) the extraction and identification of pertinent knowledge about the environmental …


Analysis Of A Clinically Failed, Mechanically Intact, Reconstructive Compression Plate, Bharadwaj Cheruvu, Sunil Karmacharya, Richard T. Laughlin, Tarun Goswami 2015 Wright State University

Analysis Of A Clinically Failed, Mechanically Intact, Reconstructive Compression Plate, Bharadwaj Cheruvu, Sunil Karmacharya, Richard T. Laughlin, Tarun Goswami

Biomedical, Industrial & Human Factors Engineering Faculty Publications

A reconstructive orthopedic bone plate was submitted for analysis. Traditional failure analysis methods were used to assess the mode of the plate failure. Metallographic investigation of the plate was carried out in this report. Since limited data was available in the literature and clinical data related to subject demography, date of removal as well as reasons for removal unknown, in depth analysis was not possible. However, the plate was received in in-tact condition with minor biological deposits and scratches, it is speculated that the failure of the plate may have been due to biological/clinical reasons, likely infection, rejecting the device …


Creation And Analysis Of Checklists To Improve Raquet Stringing Performance In Tennis Warehouse, Alston S. Nguyen 2015 California Polytechnic State University - San Luis Obispo

Creation And Analysis Of Checklists To Improve Raquet Stringing Performance In Tennis Warehouse, Alston S. Nguyen

Industrial and Manufacturing Engineering

Tennis Warehouse has a need to increase the supply of strung racquets and man hours to complete these strung racquets over the course of a year. That is, the demand can be increased by up to 4 times its average load during certain hectic parts of the year (professional tournaments, holidays, and competitive seasons). Not meeting this demand can lead to upset customers, unnecessary waste and replacing of rushed items and shipping costs, and a discouraged customer service representative workforce. The objective of this project is to use a set of checklists to address this problem and attempt to increase …


Designing Bus Transit Services For Routine Crowd Situations At Large Event Venues, Jianli DU, Shih-Fen CHENG, Hoong Chuin LAU 2015 Singapore Management University

Designing Bus Transit Services For Routine Crowd Situations At Large Event Venues, Jianli Du, Shih-Fen Cheng, Hoong Chuin Lau

Research Collection School Of Computing and Information Systems

We are concerned with the routine crowd management problem after a major event at a known venue. Without properly design complementary transport services, such sudden crowd build-ups will overwhelm the existing infrastructure. In this paper, we introduce a novel flow-rate based model to model the dynamic movement of passengers over the transportation flow network. Based on this basic model, an integer linear programming model is proposed to solve the bus transit problem permanently. We validate our model against a real scenario in Singapore, where a newly constructed mega-stadium hosts various large events regularly. The results show that the proposed approach …


Haptics-Based Cataract Surgery Simulator, Jia Luo 2015 Florida Institute of Technology

Haptics-Based Cataract Surgery Simulator, Jia Luo

Link Foundation Modeling, Simulation and Training Fellowship Reports

Surgical training using computer-based simulators are being adopted by many medical specialties, mainly because they offer several advantages to traditional training methods involving animals or cadavers. This article focuses on the design and implementation of a haptics-based cataract surgery simulator.


A Rolling Horizon Auction Mechanism And Virtual Pricing Of Shipping Capacity For Urban Consolidation Centers, Chen WANG, Hoong Chuin LAU, Yun Fong LIM 2015 SAP Innovation Centre, Singapore

A Rolling Horizon Auction Mechanism And Virtual Pricing Of Shipping Capacity For Urban Consolidation Centers, Chen Wang, Hoong Chuin Lau, Yun Fong Lim

Research Collection School Of Computing and Information Systems

A number of cities around the world have adopted urban consolidation centers (UCCs) to address challenges of last-mile deliveries. At the UCC, goods are consolidated based on their destinations prior to their deliveries into city centers. Typically, a UCC owns a fleet of ecofriendly vehicles to carry out such deliveries. Shippers/carriers that make use of the UCC’s service hence no longer need to be restricted by timewindow and vehicle-type regulations. As a result, they retain the ability to deploy large trucks for the economies of scale from the source to the UCC which is located outside the city center. Furthermore, …


Design And Research Of Vlcc Vessel Virtual Marine Engine Room, Chuang Zhao 2015 World Maritime University

Design And Research Of Vlcc Vessel Virtual Marine Engine Room, Chuang Zhao

Maritime Safety & Environment Management Dissertations (Dalian)

No abstract provided.


Research On Xiamen Port Network Layout From The Perspective Of Harbors And Inland Ports Linked Development, Yijun Zheng 2015 World Maritime University

Research On Xiamen Port Network Layout From The Perspective Of Harbors And Inland Ports Linked Development, Yijun Zheng

World Maritime University Dissertations

No abstract provided.


Effect Of The Construction Of Ftz Upon The Development Of Shanghai International Shipping Center, Yun Zhou 2015 World Maritime University

Effect Of The Construction Of Ftz Upon The Development Of Shanghai International Shipping Center, Yun Zhou

World Maritime University Dissertations

No abstract provided.


Mapping Kinematic Functional Abilities Of The Hand To Three Dimensional Shapes For Inclusive Design, Samuel T. Leitkam, Laura Bix, Javier de la Fuente, Tamara Reid Bush 2015 Michigan State University

Mapping Kinematic Functional Abilities Of The Hand To Three Dimensional Shapes For Inclusive Design, Samuel T. Leitkam, Laura Bix, Javier De La Fuente, Tamara Reid Bush

Industrial Technology and Packaging

Loss of hand function can have adverse effects on an individual's ability to maintain independence. The ability to perform daily activities, such as food preparation and medication delivery, is dependent on the hand's ability to grasp and manipulate objects. Therefore, the goal of this research was to demonstrate that three dimensional (3D) modeling of hand function can be used to improve the accessibility of handheld objects for individuals with reduced functionality through informed design. Individual models of hand functionality were created for 43 participants and group models were developed for groups of individuals without (Healthy) and with reduced functionality due …


The Influence Of Cu3(Btc)2 Metal Organic Framework On The Permeability And Perm-Selectivity Of Plla-Mof Mixed Matrix Membranes, Ajay Kathuria, Saleh Al-Ghamdi, Mohamad G. Abiad, Rafael Auras 2015 California Polytechnic State University, San Luis Obispo

The Influence Of Cu3(Btc)2 Metal Organic Framework On The Permeability And Perm-Selectivity Of Plla-Mof Mixed Matrix Membranes, Ajay Kathuria, Saleh Al-Ghamdi, Mohamad G. Abiad, Rafael Auras

Industrial Technology and Packaging

Poly(l-lactic acid) (PLLA) - 20% (w/w) and Cu3(BTC)2 metal organic framework (MOF) based mixed matrix membranes (MMMs) were fabricated by a vertical corotating twin screw microcompounder followed by an injection molding process. Water vapor, CO2, O2, and selected aroma mass transfer properties of PLLA and PLLA MMMs were evaluated. The CO2/O2 perm-selectivity of PLLA (αCO2/O2) MMMs increased from 7.6 to 10.3 with the incorporation of 20% Cu3(BTC)2 MOF. Gravimetric permeability studies of trans-2-hexenal performed at 23°C and 50% RH indicated that permeability coefficient of PLLA MMMs …


Detecting Periods Of Flight With High Task Load, James R. Parkinson, Steven J. Landry, Quang Dao, Caitlin Surakitbanharn 2015 Purdue University

Detecting Periods Of Flight With High Task Load, James R. Parkinson, Steven J. Landry, Quang Dao, Caitlin Surakitbanharn

The Summer Undergraduate Research Fellowship (SURF) Symposium

Tools that predict dangerous working conditions empirically in the cockpit could greatly improve aviation safety. In an effort to lay the groundwork for such tools, this study will investigate whether a link exists between task load and pilots’ control strategies, their biometric data, and their planes’ position data. Using X Plane simulation software, an experiment will be run in which licensed pilots will fly a 3-nautical-mile approach into Mineta San Jose International Airport 4 times, under different task load conditions. During the flight, participants’ pupil diameters will be recorded along with the simulated aircraft position data and cognitive control modes. …


Identifying Mode Confusion In Recorded Aircraft Data, James Douglas Thomas, Yul Kwon, Steven J. Landry 2015 Purdue University

Identifying Mode Confusion In Recorded Aircraft Data, James Douglas Thomas, Yul Kwon, Steven J. Landry

The Summer Undergraduate Research Fellowship (SURF) Symposium

In recent decades, commercial aviation accidents have occurred due to human-machine interaction (HMI) problems known as “mode confusion.” This is caused, in some cases, by a lack of understanding of onboard systems by pilots. Large amounts of Flight Operational Quality Assurance (FOQA) data are available, analysis of which could assist in identification of safety risks in daily operations. Through analysis of pilot reactions and recorded aircraft data, methods to detect mode confusion are developed to improve aviation safety. This study was conducted by inducing mode confusion into a flight simulation scenario and analyzing aircraft data to detect emerging patterns. Three …


Exploring The Adoption And Use Of The Smartphone Technology In Emerging Regions: A Literature Review And Hypotheses Development, Fahad Aldhaban, Tugrul Unsal Daim, Robert R. Harmon 2015 Portland State University

Exploring The Adoption And Use Of The Smartphone Technology In Emerging Regions: A Literature Review And Hypotheses Development, Fahad Aldhaban, Tugrul Unsal Daim, Robert R. Harmon

Engineering and Technology Management Faculty Publications and Presentations

Users’ acceptance of a new information technology (IT) is a determining factor of its market success. A solid understanding of the users’ adoption process and use behavior enables a more robust definition of user requirements and better market alignment. This is especially important in markets characterized by rapid technological change such as smartphones. The Technology Acceptance Model (TAM) is often used to assess the factors affecting adoption of new technologies. However, TAM models often omit the role of important variables such as human and social factors in the adoption process. In developing markets such as China, cultural and social influences …


Financial Analysis And Comparison Of Compact Electric And Gasoline Cars, Jing Jiang, Alexander Blank, Felix Maier, Anjan Bharthepudi 2015 Biamp Systems Inc.

Financial Analysis And Comparison Of Compact Electric And Gasoline Cars, Jing Jiang, Alexander Blank, Felix Maier, Anjan Bharthepudi

Engineering and Technology Management Faculty Publications and Presentations

In the paper, a PESTLE (political, economic, social, technical, legal, and environmental) analysis is used to conduct an initial evaluation for electric vehicles (EV) and gasoline cars. Furthermore, two cash flow models are created to describe the scenarios of both gasoline and electric car respectively. Based upon the proposed models, the equivalent uniform annual cost (EUAC) methodology is used to calculate the cost during the period of car ownership. Four compact EVs and five compact gasoline cars are selected in the analysis. The results expose that the actual return of federal tax credit impacts the EUAC value. The 50% return …


Siting A Wind Farm In Oregon: Considering A Hierarchical Decision Model With Four Scenarios, Diane Yates 2015 Portland State University

Siting A Wind Farm In Oregon: Considering A Hierarchical Decision Model With Four Scenarios, Diane Yates

Engineering and Technology Management Faculty Publications and Presentations

This paper primarily serves two purposes: first, it looks to develop a methodology that takes scenarios and certain hard-to-measure intangibles such as politics, social impact, and even religion; as well as more tangible and measurable variables such as environmental impacts, cost and types of materials, storage and wind turbine technologies, to name a few, that then could be used as input to a decision-making model on where to build a wind farm. The hierarchical decision model (HDM) then analyzes these variables, based on an independent judging panel, in order to come up with a recommendation for the best site on …


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