Individualized Bayesian Inference Identifies Novel Genetic Variants For Parkinson's Disease,
2026
Missouri University of Science and Technology
Individualized Bayesian Inference Identifies Novel Genetic Variants For Parkinson's Disease, Jin Ren, Yasaman J. Soofi, Md Asad Rahman, Qing Lu, Jinling Liu
Engineering Management and Systems Engineering Faculty Research & Creative Works
Parkinson's disease (PD) is a complex neurodegenerative disorder with a significant genetic component. While genome-wide association studies (GWAS) have been instrumental in identifying genetic variants associated with PD, the reliance on large sample sizes and population-level analyses may overlook variants with lower minor allele frequencies or individual-specific relevance. Individualized Bayesian Inference (IBI) offers a promising method to complement GWAS by identifying and prioritizing candidate genetic markers at both the individual and patients-like-me subgroup levels. This study evaluates the application of IBI to PD genetics, using GWAS as a baseline for comparison. We analyzed genetic data from the Fox Insight online …
Determination Of The Content Of Water-Soluble Vitamins In The Composition Of Beet Beetroot Composition,
2026
Tashkent state technical university named after Islam Karimov. Address: Universitetskaya street 2, 100095, Tashkent city, Republic of Uzbekistan. E-mail: [email protected], Phone: +99893 569-02-88;
Determination Of The Content Of Water-Soluble Vitamins In The Composition Of Beet Beetroot Composition, Jasur Esirgapovich Safarov, Shakhnoza Abduvaxitovna Sultanova, Muhammad Rasul Oglu Najafli, Doston Ishmuhammat Ugli Samandarov
Chemical Technology, Control and Management
The aim of this study was to determine the content of water-soluble vitamins in various parts of beetroot (pulp, leaves and stems) that had been subjected to various drying methods in a bid to explore the effect of physical processes, i.e., the application of ultrasound, on micronutrient preservation. The experiments were performed at the Department of Service Technologies of Tashkent State Technical University, and chromatographic analysis was performed in the Institute of Bioorganic Chemistry of the Academy of Sciences of the Republic of Uzbekistan. Chromatography was performed on Agilent-1200 chromatograph with Exlipse XDB C18 column and diode array detector using …
Methods For Treating Wastewater Generated During The Production Of Basalt Fiber Using Modified Bentonite Clay,
2026
Jizzakh Polytechnic Institute. Address: 130100. Jizzakh city, Islam Karimov str 4, Republic of Uzbekistan. E-mail: [email protected], https://orcid.org/0009-0004-4255-6266;
Methods For Treating Wastewater Generated During The Production Of Basalt Fiber Using Modified Bentonite Clay, Abdurasul O'Ktamovich Husenov, Baxtiyor Toxtayevich Sabirov, Diyor Asadullayevich Xadjibayev
Chemical Technology, Control and Management
This scientific article notes that in technological processes, wastewater is contaminated with various organic and mineral substances, including poisonous and toxic substances. Sources of environmental pollution include organic and inorganic substances formed during the production of basalt fiber. In this research work, the task is set to purify wastewater formed during the production of basalt fiber from organic substances. Bentonite clay is a very good natural sorbent and has the ability to purify some cations. When conducting laboratory experiments, bentonite clays from the "Azkamar" and "Navbahor" deposits were selected to purify wastewater formed during the production of basalt fiber from …
Mathematical Models Of Magnetoelastic Acceleration Transducers Developed Based On The Theory Of Lumped Parameter Circuits,
2026
Doctor of Technical Sciences, Professor of "Power Supply" Chair, Tashkent State Transport University. Adress: Uzbekistan, Tashkent city, Temiryulchilar street 1. E-mail: [email protected]. Phone: +998911370295;
Mathematical Models Of Magnetoelastic Acceleration Transducers Developed Based On The Theory Of Lumped Parameter Circuits, Amirov Fayzullayevich Sulton, Kamila Kamilovna Jurayeva, Shovkat Dilshodovich Turayev
Chemical Technology, Control and Management
In this article, based on the theory of lumped-parameter circuits, algebraic and differential equations describing the mechanical, electrical, and magnetic circuits of new magnetoelastic acceleration transducers, their analytical solutions, as well as mathematical models establishing the relationship between the electromotive forces at the outputs of the transducers and acceleration, which is the input quantity of the transducer, have been developed. Analysis of these mathematical models and the graphs constructed on their basis shows that under the influence of acceleration applied to the transducers, with an increase in the mechanical stresses arising in the magnetic circuit of the transducer, a redistribution …
Optimal Procedure For Measuring The Parameters Of Optical Signals Considering Noise,
2026
Tashkent State Technical University. Address: st. Universitetskaya 2, 100095, Tashkent, Republic of Uzbekistan. E-mail: [email protected];
Optimal Procedure For Measuring The Parameters Of Optical Signals Considering Noise, Yuriy Gennadyevich Shipulin, Azimjon Mamadaliyevich Xusanov
Chemical Technology, Control and Management
It has been shown that to achieve the required level of measurement accuracy and reliability, it is necessary to transition from quality control of finished products to quality management based on cost-effective methods during the stages when product properties are formed. It is shown that the complexity of measuring optical signal parameters during analysis or synthesis requires them to be considered as part of a general information processing system. Based on the nonlinear filtration method, an optimal procedure for measuring a variable position in time against a background of spatial noise was obtained. Structural diagrams of optimal measuring instruments for …
Development And Uncertainty Assessment Of Secondary Method For Ph Measurement In Physicochemical Measurements,
2026
Tashkent State Technical University. Address: 2 Universitet st., 100095, Tashkent, Uzbekistan. E-mail: sarvar.raxmatullayev90@gmail.сom (orсid.org/ 0000-0001-7901-6600);
Development And Uncertainty Assessment Of Secondary Method For Ph Measurement In Physicochemical Measurements, Sarvar Rakhmatullaev, Dostonbek Xujakulov, Mohinur Nigmatova
Chemical Technology, Control and Management
In physicochemical measurements across various industries, laboratory analyses commonly require the determination of pH as an indicator of hydrogen ion activity in aqueous solutions. Ensuring the accuracy and reliability of these measurements, obtaining precise readings from pH measuring instruments, and maintaining overall measurement quality represent critical challenges in guaranteeing the safety of both products and processes. This requires constant monitoring, accuracy assessment, calibration, metrological verification, and control of measuring instruments. In this case, it should be carried out not with solutions prepared in any laboratory, but with certified reference materials (СRM) with appropriate regulatory framework, ensuring metrological observation. …
Robust-Adaptive Estimation Of Unmeasurable States And External Disturbances Of A Dynamic Object Based On An Augmented Kalman Filter,
2026
academician of the Academy of Sciences of the Republic of Uzbekistan, doctor of technical sciences, professor of the department “Information Processing Systems and Control” at Tashkent state technical university named after Islam Karimov. Address: 100095, University str. 2, Tashkent, Uzbekistan. E-mail: [email protected];
Robust-Adaptive Estimation Of Unmeasurable States And External Disturbances Of A Dynamic Object Based On An Augmented Kalman Filter, Husan Igamberdiev, Uktam Farkhodovich Mamirov, Lu Liu, Bohong Wang, Bunyod Buronov
Chemical Technology, Control and Management
The paper addresses the problem of joint estimation of the directly unmeasurable states of a dynamic object and of external disturbances when information is available only on the control inputs and on the measured output signals. To solve this problem, a robust-adaptive algorithm based on an augmented Kalman filter is proposed, in which the external disturbance is included in the extended state vector. Two operating modes of the algorithm are considered. For slowly varying disturbances, a random-walk model with a constant process-noise covariance is used, whereas for rapidly varying inputs a signal adaptation driven by the normalized innovation is proposed. …
Fast Algorithms For Combined Synthesis Of Dynamic Object Control Systems,
2026
Tashkent State Technical University. Address: 2 Universitetskaya st., 100095, Tashkent city, Republic of Uzbekistan. E-mail: [email protected], Phone: (88) 700-52-68;
Fast Algorithms For Combined Synthesis Of Dynamic Object Control Systems, Isomiddin Khakimovich Siddikov, Gulchexra Alimova
Chemical Technology, Control and Management
The paper considers the issues of combined synthesis of a control system for a nonlinear dynamic object. The combined synthesis algorithms are based on the hybrid application of the theory of ordinary differential equations in the Cauchy form and the theory of automatic control. In this case, the dynamics of the control system are described in the input-output representation and by state-space equations. Algorithms for solving stabilization problems, finite control, and the inverse dynamics problem are presented in explicit form. These algorithms are based on the concept of reducibility of a general Cauchy-form system to the block-canonical Frobenius form. The …
Nonlinear System Identification Based On Fuzzy Radial Basis Neural Network With Multi-Connected Weight Connections,
2026
Department of Applied Informatics, Kimyo International University in Tashkent. Address: st. Shota Rustaveli, 156, 100121 Tashkent, Uzbekistan. E-mail: [email protected], Phone: +998-91-371-51-27.
Nonlinear System Identification Based On Fuzzy Radial Basis Neural Network With Multi-Connected Weight Connections, Kabul Khudaybergenov
Chemical Technology, Control and Management
This paper builds on our earlier radial basis function network with multiple connections (RBFMC) by placing it within a fuzzy inference framework for nonlinear system identification. The idea is inspired by the diversity of neurotransmitters found in biological neurons: instead of a single hidden-to-output weight, RBFMC gives each hidden unit a multi-dimensional connection whose components act as independent filters. Once fuzzy logic is added, each hidden neuron becomes a fuzzy rule, and its antecedent is built from several Gaussian membership functions, one per connection. The resulting Fuzzy RBFMC produces an interpretable, multi-filter description of local regions of the input space …
Performance Evaluation Of Controllers Using Fuzzy Delphi And Ahp Techniques,
2026
Azerbaijan State Oil and Industry University. Address: 20 Azadlig Avenue, AZ1010, Baku, Azerbaijan. Email: [email protected];
Performance Evaluation Of Controllers Using Fuzzy Delphi And Ahp Techniques, Kamala. R. Aliyeva, Nihad Mehdiyev, Shamil Mehdi
Chemical Technology, Control and Management
This study introduces an enhanced decision-support framework that integrates the Fuzzy Delphi method with the Analytic Hierarchy Process (AHP) to improve controller tuning and performance evaluation in uncertain environments. Traditional tuning techniques typically depend on crisp expert judgments and deterministic performance indices; however, industrial control systems are characterized by nonlinear behaviors, uncertain parameter variations, and subjective expert evaluations that are often vague or inconsistent. The Fuzzy Delphi procedure is applied to systematically gather, filter, and consolidate expert insights, enabling a refined set of performance criteria such as stability margins, robustness to disturbances, settling time, overshoot, control effort, and energy consumption …
Documentation And Project Change Management System – Honeywell Trace,
2026
XIMAVTOMATIKA” Ltd, Uzbekistan. Address: 1 Niyozbek yuli str., 100000, Tashkent city, Republic of Uzbekistan. E-mail: [email protected];
Documentation And Project Change Management System – Honeywell Trace, Farukh Adilov, N.R Yusupbekov, Maksim Fedorovich Astafurov, Kamola Rustamovna Abdullayeva
Chemical Technology, Control and Management
The article examines modern approaches to organizing documentation and managing changes in industrial automation projects using the Honeywell Trace software platform. The evolution of documentation tools from the Documentation Tool utility within the TDC 2000/3000 system to modern intelligent solutions is described. The architecture, functional capabilities, and supported interfaces of Honeywell Trace are analyzed. Particular attention is paid to automated configuration change tracking, comprehensive search by process tags, and the detection of potential errors. The possibilities of integrating the system with industrial process control systems, controllers, auxiliary systems, and industrial communication protocols are considered. The application of Honeywell Trace during …
Exploring Red Palm Oil As A Sustainable Plasticizer For Carbon Black-Filled Ssbr/Br Tire Tread Compounds: A Comparative Evaluation Of Commercial Alternatives,
2026
Bogor-Getas Research Unit-Indonesian Research Institute for Estate Crops (PT RPN), Salak No. 1A Street, Bogor, West Java, 16128, Indonesia
Exploring Red Palm Oil As A Sustainable Plasticizer For Carbon Black-Filled Ssbr/Br Tire Tread Compounds: A Comparative Evaluation Of Commercial Alternatives, Norma Arisanti Kinasih, Mohamad Irfan Fathurrohman, Santi Puspitasari, Dewi Kusuma Arti, Abdulhakim Masa
Journal of Materials Exploration and Findings
This study investigates the application of red palm oil (RPO) as an alternative vegetable oil resource to substitute petroleum-based plasticizers, which have environmental and health concerns, in carbon black (CB)-filled SSBR/BR tire tread compounds. The plasticizing effects of RPO were thoroughly evaluated by comparing them with a commercial bio-based plasticizer, Epoxidized Soybean Oil (ESBO), and two safer petroleum-based oils, Naphthenic Oil (NYNAS) and Treated Distillate Aromatic Extract (TDAE). The initial investigation shows that fatty acid composition is imposing regarding the plasticizing effect. The higher unsaturated fatty acid content in RPO than in ESBO improved tensile strength and degraded rolling resistance …
Techno-Economic Analysis Of The Utilization Of Waste-To-Energy In Jakarta Industrial Estate Pulogadung,
2026
Department of Interdisciplinary Engineering, Faculty of Engineering, Universitas Indonesia Kampus Baru UI Depok, Depok, West Java 16424 Indonesia
Techno-Economic Analysis Of The Utilization Of Waste-To-Energy In Jakarta Industrial Estate Pulogadung, Wahyu Punjung Pesonagrata, Mohammad Akita Indianto
Journal of Materials Exploration and Findings
Indonesia has a serious waste problem, which ranking second in marine pollution. Due to significant environmental impacts, a solution to overcome the complexity of waste problems is needed. This study took sample on waste management in Jakarta Industrial Estate Pulogadung (JIEP). JIEP is an Industrial area which covers 443 hectares of land in East Jakarta. This study aims to address Indonesia's serious waste problem by exploring the potential utilization of waste in the Jakarta Industrial Estate Pulogadung (JIEP) as Refuse-Derived Fuel (RDF) for a waste-to-energy (WtE) power plant. The proposed method used a steam power plant with RDF as fuel …
Metallurgical Investigation Of A Modified Eye Bolt Failure Caused By Improper Weld Extension, Specification Deviation, And Crevice Corrosion,
2026
Department of Metallurgical and Materials Engineering, Faculty of Engineering, Universitas Indonesia, Depok, West Java, 16424, Indonesia
Metallurgical Investigation Of A Modified Eye Bolt Failure Caused By Improper Weld Extension, Specification Deviation, And Crevice Corrosion, Dimas Muhammad Fawwaz, Reza Miftahul Ulum, Johny Wahyuadi Soedarsono, Yudha Pratesa
Journal of Materials Exploration and Findings
A modified eye bolt from the David Arm Manhole Storage Tank underwent thorough metallurgical study due to the consequences of the bolt's malfunction during operation. Safety issues arose when the manhole door detached during operation. The mechanical testing and chemical composition analysis of the bolts indicated they were manufactured from an ASTM A193 Grade B7 material used for high-temperature bolting. This material did not conform to the engineering drawing, which mentioned SA 563A, which is about nuts, not bolts. This contradiction clearly shows that the eye bolt which was installed does not conform to the intended design. Welded connections of …
Rejection Of Fe (Iron) And Kmno4 (Organic Substance) Parameters In Peat Water Using Organic Membranes,
2026
Department of Environmental Engineering, Faculty of Engineering, Batanghari University, Jambi City, Sumatra, 36122, Indonesia
Rejection Of Fe (Iron) And Kmno4 (Organic Substance) Parameters In Peat Water Using Organic Membranes, Muhamad Rafli Sakti Mulia Gonera, Siti Umi Kalsum, Sarah Fiebrina Heraningsih
Journal of Materials Exploration and Findings
Peat water is a surface water source widely used by people in swampy and lowland areas, but it has poor quality characteristics such as high organic matter content, low pH, and dissolved metal levels such as iron that exceed the threshold. These conditions can cause health problems and reduce the quality of clean water so that effective treatment technology is needed. This study aims to analyze the effectiveness of ultrafiltration membranes made from chitosan from shrimp shell waste in rejecting iron (Fe) and organic substances in peat water, and to determine the effect of pressure on separation performance. This study …
Optimization Of Gas Consumption, Cost And Production Rate For Computerized Numerical Control Oxy-Acetylene Flame Cutters,
2026
Department of Mechanical and Industrial Engineering, University of Dar es Salaam, P.O. Box 35131, Dar es salaam Tanzania.
Optimization Of Gas Consumption, Cost And Production Rate For Computerized Numerical Control Oxy-Acetylene Flame Cutters, Eustace K. William, Simon I. Marandu, Enock W. Nshama
Tanzania Journal of Science
This study examined the impact of flame cutting parameters (i.e., cutting speed, plate thickness and nozzle diameter) on oxy-acetylene gas consumption, cost and production rate. A full factorial design of experiments was used to generate 27 experiments, which were conducted using a CNC flame cutter. The analysis of variance (ANOVA) method was used to determine significant process parameters, followed by regression analysis using the MINITAB ® software. The technique for order preference by similarity to ideal solutions (TOPSIS) was used to determine the optimal cutting parameters for minimizing the consumption and cost estimation of oxy- acetylene gas and maximizing the …
Instructional Fidelity In Virtual Flight: Applying A Structured Learning Model For Vr-Based Pilot Training,
2026
Louisiana Tech University
Instructional Fidelity In Virtual Flight: Applying A Structured Learning Model For Vr-Based Pilot Training, Lindsay Gouedy, Bryce Jarrell, Mary Fendley, Brandon Wolf
Journal of Aviation/Aerospace Education & Research
As immersive training technologies reshape the future of aviation education, this study explores the impact of integrating Virtual Reality (VR) into a structured instructional model for B-52 pilot training. With the development and implementation of the I-BUFF (Integrated B-52 Unit Flight Familiarization) model, an innovative framework built upon the 4C/ID (Four Component Instructional Design) and SEEV (Salience, Effort, Expectancy, Value) models, this research evaluates whether structured VR environments improve training transfer and accelerate task proficiency for in-air refueling tasks. A sample of 233 pilot trainees was assessed across three groups: traditional training (non-VR unstructured), VR semi-structured, and VR fully structured …
Utilising Video Recordings To Assess Student Pilot Performance: An Exploratory Study During A Simulated Training Flight,
2026
University of Waterloo
Utilising Video Recordings To Assess Student Pilot Performance: An Exploratory Study During A Simulated Training Flight, Bradley Moncion, Shi Cao, Allison Lynch, Suzanne K. Kearns, Elizabeth Irving, Ewa Niechwiej-Szwedo
Journal of Aviation/Aerospace Education & Research
In ab initio flight training, the quality of the feedback a flight instructor provides their student is essential to their success. While other high-performance and safety-critical industries have incorporated the use of video recordings into training and assessments, the aviation industry generally has not. There are some studies addressing the potential benefits of video recordings in training professional pilots, but there is a lack of research at the ab initio level. In this study, five flight instructors assessed the performance of student pilots conducting a simulated training flight using a 4-point marking scale. The flights instructors were then tasked with …
Evaluation Of Tactile Cueing Embedded In An Aviation Headset On Pilot Altitude Control,
2026
University of North Dakota
Evaluation Of Tactile Cueing Embedded In An Aviation Headset On Pilot Altitude Control, Nicholas D. Wilson, Jessica Van Bree, Matthew Cleveland, Sunny Charakuru, Thomas Petros, Richard Ferraro, Kouhyar Tavakolian
Journal of Aviation/Aerospace Education & Research
This study evaluated the effectiveness of tactile cueing integrated into a pilot’s headset on pilot altitude control during simulated instrument conditions. Pilots typically rely on visual and auditory inputs to maintain situational awareness, but in high-workload or instrument meteorological conditions (IMC), these channels can become overloaded. One underutilized alternative for alerting is a tactile cueing apparatus. Using an X-Plane simulation of a Piper Archer equipped with a G-1000 avionics suite, 39 FAA-certified pilots flew two precision approaches. The experimental group (n = 20) received haptic cues via ear seal-embedded tactors when deviating from assigned altitude or glideslope. The control group …
Engineering For Compromise,
2026
Dartmouth College
Engineering For Compromise, Ron Ross
Other Faculty Materials
Modern systems cannot credibly depend on every component, account, service, person, supplier, and supporting dependency remaining trustworthy secure throughout the system life cycle. Prevention-centered cybersecurity remains essential, but for mission-critical systems it is not a sufficient engineering strategy. This paper introduces the concept of Engineering for Compromise (EfC), a systems security engineering strategy that deliberately assumes selected system elements may fail, become malicious, lose integrity, or fall under adversary control and then asks whether the system can continue to prevent unacceptable loss. EfC separates component compromise, system compromise, and mission loss as distinct events and uses architecture to place barriers …
