Operational Research Commons^™

Adaptive Design And Flexible Approval Of Clinical Trials, Saeid Delshad Sisi

All Dissertations

Dose-finding clinical trials are among the most critical cornerstones of the healthcare system. In this broad research area, there are many decision making problems that are extremely challenging to address. However, a small improvement may result in significant benefits to the society. Dose-finding clinical trials are extremely expensive and require multiple time-consuming and complicated R&D phases. Despite all the costs and the long time these trials need to conclude (on average over ten years for each new drug/technology), only less than 15\% of these trials successfully end up in a new approved drug entering the market. This problem is even …

Park Equity Modeling: A Case Study Of Asheville, North Carolina, Anisa Young

All Theses

Parks and greenspaces are publicly available entities that serve the vital purpose of promoting multiple aspects of human welfare. Unfortunately, the existence of park disparities is commonplace within the park setting. Specifically, marginalized individuals encounter limited park access, insufficient amenity provision, and poor maintenance. To remedy these disparities, we propose a process in which we select candidate park facilities and utilize facility location models to determine the optimal primary parks from both existing and candidate sites.

We note that platforms currently exist to identify the geographical areas where residents lack sufficient access to parks. However, these platforms do not yet …

Modeling The Impact And Accelerating The Process Of Transitioning To A Sustainable Healthy Diet Through Decision Support Systems, Prince Agyemang

Graduate Theses and Dissertations

Food production and consumption are essential in human existence, yet they are implicated in the high occurrences of preventable chronic diseases and environmental degradation. Although healthy food may not necessarily be sustainable and vice versa, there is an opportunity to make our food both healthy and sustainable. Attempts have been made to conceptualize how sustainable healthy food may be produced and consumed; however, available data suggest a rise in the prevalence of health-related and negative environmental consequences of our food supply. Thus, the transition from conceptual frameworks to implementing these concepts has not always been effective. This paper explores the …

Implementation Of Lean And Six Sigma Methodologies To Improve The Operations And Efficiencies Of An Inpatient Pharmacy, Brian Ricks

Medical Engineering Theses

Reducing overhead costs and eliminating process waste are important aspects of any successful organization. Hospital processes are frequently interconnected, with many exchanges of both materials and information between departments. The Inpatient Pharmacy, a key component of any hospital, has hundreds of interactions between departments on any given day, and many processes see the pharmacy acting as producers, consumers, and transporters of goods throughout the hospital. Such a varied role provides broad opportunities for process improvement. Within the broader manufacturing world, the philosophies of Lean and Six Sigma have helped many companies increase their process efficiencies, reduce costs, and increase quality. …

Credit Card Fraud Detection Using Machine Learning Techniques, Nermin Samy Elhusseny, Shimaa Mohamed Ouf, Amira M. Idrees Ami

Future Computing and Informatics Journal

This is a systematic literature review to reflect the previous studies that dealt with credit card fraud detection and highlight the different machine learning techniques to deal with this problem. Credit cards are now widely utilized daily. The globe has just begun to shift toward financial inclusion, with marginalized people being introduced to the financial sector. As a result of the high volume of e-commerce, there has been a significant increase in credit card fraud. One of the most important parts of today's banking sector is fraud detection. Fraud is one of the most serious concerns in terms of monetary …

Estimation Of Storage Tank Capacities For Different Roofing Areas For Rainwater Harvesting In Dodoma Urban, Tanzania, Ombeni J. Mdee

Tanzania Journal of Engineering and Technology (TJET)

This study uses a mass balance model and economic analysis technique to present an estimation of roofing areas and storage tank capacity for Rainwater Harvesting (RWH) system. The water-saved benefits were estimated using the monthly rainfall of over 39 years from 1981 to 2020 and five roofing areas. The proposed roof-storage-ratio method presents the minimum requirement of roof area and storage tank size when the ratio value is closer to 1. The benefit-cost ratio and percentage of reliability indicated the optimal roofing areas ranging between 200 and 300 m2 for storage tank capacity between 20 and 25 m3, with a …

Training Thinner And Deeper Neural Networks: Jumpstart Regularization, Carles Riera, Camilo Rey, Thiago Serra, Eloi Puertas, Oriol Pujol

Faculty Conference Papers and Presentations

Neural networks are more expressive when they have multiple layers. In turn, conventional training methods are only successful if the depth does not lead to numerical issues such as exploding or vanishing gradients, which occur less frequently when the layers are sufficiently wide. However, increasing width to attain greater depth entails the use of heavier computational resources and leads to overparameterized models. These subsequent issues have been partially addressed by model compression methods such as quantization and pruning, some of which relying on normalization-based regularization of the loss function to make the effect of most parameters negligible. In this work, …

Reconciliation, Restoration And Reconstruction Of A Conflict Ridden Country, Muhammad S. Riaz

Theses and Dissertations

Conflict has sadly been a constant part of history. Winning a conflict and making a lasting peace are often not the same thing. While a peace treaty ends a conflict and often dictates terms from the winners’ perspective, it may not create a lasting peace. Short of unconditional surrender, modern conflict ends with a negotiated cessation of hostilities. Such accords may have some initial reconstruction agreements, but Reconciliation, Restoration and Reconstruction (RRR) is a long term process. This study maintains that to achieve a lasting peace: 1) The culture and beliefs of the conflict nation must be continuously considered and …

Optimization And Information Problems In Operations, Puping Jiang

Olin Business School Graduate Student Theses and Dissertations

The main purpose of this dissertation is to study the optimization problems and the value of information in various commercial settings, especially in the emerging platform economy.

Chapter 1, “Data-Driven Asset Selling”. Motivated by online asset selling marketplace business (e.g., used cars and real estate), we formulate a data-driven asset selling dynamic pricing framework which utilizes platforms’ access to customers’ online behavioral data. With mild assumptions on the demand model, careful characterization of the problem structure shows that the model admits some ideal properties that facilitate our regret analysis under our dynamic programming setting. Instead of studying the policy performance …

Analyzing Vulnerabilities In The Northwest Arkansas Highway Network Using Mathematical Optimization, Brandon Jerome

Industrial Engineering Undergraduate Honors Theses

The highway and bridge network is a critical infrastructure that allows for the free transportation of citizens and enables truck-borne freight transportation. Disruption of this system could be caused by a terrorist attack, natural disaster, growth of population, required repairs and upgrades, or collapse caused by old age or malfunction. In the event of a disruption cities and regions can experience increased traffic and supply chain shortages, thus causing cascading effects throughout surrounding areas. With this motivation, we develop a network interdiction optimization model to identify a limited subset of roads that, if disrupted, causes the greatest increase in the …

Academic Advising Support Tool: An Optimization Approach, Spencer Loper

Industrial Engineering Undergraduate Honors Theses

More than ever, a college education is necessary to remain competitive in the job market. Therefore, colleges are dedicating numerous resources to ensure student success. Nonetheless, one of the most important factors of student success is proper academic advising. Students at the University of Arkansas and more specifically within the department of Industrial Engineering department are fortunate to have access to fantastic advising. However, given the volume of students, academic advisors do not have the time to talk through the nuance of every student’s long-term academic plan. The department does provide an eight-semester plan; however, students who have deviated from …

Selected Interdiction Games With Uncertain, Risk-Averse, And Simultaneous Play Considerations, Di H. Nguyen

All Dissertations

This dissertation examines two network interdiction problems: a shortest-path interdiction problem under uncertainty and a network interdiction problem in a simultaneous game. Both problems happen in two stages over a directed network, and involve a leader and a follower who have opposing interests.

In the first problem, the leader acts first to lengthen a subset of arcs, and a follower acts second to select a shortest path across the network. The cost for a follower’s arc consists of a base cost if the arc is not interdicted, plus an additional cost that is incurred if the arc is interdicted. The …

Design And Analysis Of Efficient Freight Transportation Networks In A Collaborative Logistics Environment, Vishal Badyal

All Dissertations

The increase in total freight volumes, reducing volume per freight unit, and delivery deadlines have increased the burden on freight transportation systems of today. With the evolution of freight demand trends, there also needs to be an evolution in the freight distribution processes. Today's freight transportation processes have a lot of inefficiencies that could be streamlined, thus preventing concerns like increased operational costs, road congestion, and environmental degradation. Collaborative logistics is one of the approaches where supply chain partners collaborate horizontally or/and vertically to create a centralized network that is more efficient and serves towards a common goal or objective. …

Comparing Actively Managed Mutual Fund Categories To Index Funds Using Linear Regression Forecasting And Portfolio Optimization, Luke Weiner

Industrial Engineering Undergraduate Honors Theses

The global investment industry offers a wide variety of investment products especially for individual investors. One such product, index funds, which are younger than actively managed mutual funds, have typically outperformed managed funds. Despite this phenomenon, investors have displayed a tendency to continue investing in actively managed funds. Although only a small percentage of actively managed funds outperform index funds, the costs of actively managed funds are significantly higher. Also, managed fund performances are most often determined by their fund category such as growth or real estate. I wanted to answer the following question for individual investors: can we …

Supervised Representation Learning For Improving Prediction Performance In Medical Decision Support Applications, Phawis Thammasorn

Graduate Theses and Dissertations

Machine learning approaches for prediction play an integral role in modern-day decision supports system. An integral part of the process is extracting interest variables or features to describe the input data. Then, the variables are utilized for training machine-learning algorithms to map from the variables to the target output. After the training, the model is validated with either validation or testing data before making predictions with a new dataset. Despite the straightforward workflow, the process relies heavily on good feature representation of data. Engineering suitable representation eases the subsequent actions and copes with many practical issues that potentially prevent the …

Predicting The Likelihood And Scale Of Wildfires In California Using Meteorological And Vegetation Data, Matthew Walters

Graduate Theses and Dissertations

Wildfires have devastating ecological, environmental, economical, and public health impacts through the deterioration of water and air quality, CO2 emissions, property damage, and lung illnesses. The early detection and prevention of wildfires allow for the minimization of these risks. The use of Artificial Intelligence (AI) in wildfire detection and prediction has been highly researched as a tool to assist firefighters in stopping wildfires in its early stages. The three common wildfire prediction categories include image and video detection, behavior prediction, and susceptibility prediction. Data such as climate, weather, vegetation, satellite images, and historical wildfire data is most commonly used. Many …

The Impact Of Reliability In Conceptual Design - An Integrated Trade-Off Analysis, Tevari James Barker

Graduate Theses and Dissertations

Research presented in this paper focuses on developing models to estimate the systemreliability of Unmanned Ground Vehicles using knowledge and data from similar systems. Traditional reliability approaches often require detailed knowledge of a system and are used in later design stages as well as development, operational test and evaluation, and operations. The critical role of reliability and its impact on acquisition program performance, cost, and schedule motivate the need for improved system reliability models in the early design stages. Reliability is often a stand-alone requirement and not fully included in performance and life cycle cost models. This research seeks to …

Forecasting Hypotension By Learning From Multivariate Mixed Responses.., Jodie Ritter

Electronic Theses and Dissertations

Blood Pressure is the main determinant of blood flow to organs. Hypotension is defined as a systolic blood pressure less than 90 mmHg or a diastolic blood pressure less than 50 mmHg. The severity and duration of hypotension is associated with low blood flow to organs often result in organ damage and a high mortality rate. Predicting hypotension prior to surgery and during the surgery can reduce the incidence and duration resulting in better patient outcomes. This thesis uses preoperative bloodwork and vital signs as well as perioperative vital signs in 5-minute increments as inputs to forecast hypotension. Hypotension can …

Finding Core Members Of A Hedonic Game, Daniele M. Vernon-Bido

Computational Modeling & Simulation Engineering Theses & Dissertations

Agent-based modeling (ABM) is a frequently used paradigm for social simulation; however, there is little evidence of its use in strategic coalition formations. There are few models that explore coalition formation and even fewer that validate their results against an expected outcome. Cooperative game theory is often used to study strategic coalition formation but solving games involving a significant number of agents is computationally intractable. However, there is a natural linkage between ABM and the study of strategic coalition formation. A foundational feature of ABM is the interaction of agents and their environment. Coalition formation is primarily the result of …

Factors Affecting Hotel Recommendation: Before The Covid-19 Pandemic And After The Reopening, Boran Kim

UNLV Theses, Dissertations, Professional Papers, and Capstones

During the COVID-19 pandemic, numerous people lost their lives, and a lot of industries were affected. The hospitality industry was especially affected due to social distancing, travel restrictions, and safety issues. During that time, not only did customers' expectations change but their recommendation of hotels to friends and colleagues also changed. The current study used five factors (i.e., cleanliness, location, room, service, and value) to discover which factors were affecting hotel recommendation before the COVID-19 pandemic and after the reopening. This study used secondary data (online surveys) from one of the well-known integrated resorts located in the western United States. …