Industrial Engineering Commons^™

Gender-Specific Anterior Cruciate Ligament – Gait Forces, Bharadwaj Cheruvu, Amy Neidhard-Doll, Tarun Goswami

Biomedical, Industrial & Human Factors Engineering Faculty Publications

The purpose of this study was to investigate gender-based differences in gait biomechanics and to evaluate those effects on forces generated on the ACL during walking. Estimation of gender-specific ACL forces in the frontal plane can provide a better understanding of the biomechanical patterns underlying higher female injury risk. The present study used a sample from the Fels Longitudinal Study to test the hypothesis that there are significant gender-differences in frontal plane ACL loading during walking. A cross-sectional sample of 178 participants, including 79 males and 99 females was used to evaluate differences in gait kinetics. Females walked at higher …

Simulation Of Gene Regulatory Elements For Biosensing, Mallory Bates, Svetlana Harbough, Tarun Goswami

Biomedical, Industrial & Human Factors Engineering Faculty Publications

Gene regulatory studies are of significant importance in many scenarios such as mental illness. 21% of U.S adults experience mental illnesses including 1 in 4 active-duty military personnel. Mental health can be identified in the body by different biomarkers. These biomarkers potentially controlled by riboswitches, which are located in mRNA and switch “ON” or “OFF” depending on the concentration of a biomarker. In this research, a known riboswitch reengineered and its response in the presence of a biomarker investigated. We changed computationally PreQ₁, a known riboswitch that has the smallest aptamer, and then experimentally tested against biomarkers, dehydroepiandrosterone-sulfate …

Modeling Multi-Criteria Decision-Making Problems With Applications In Last Mile Delivery And School Safety Assessment, Ayat Alrahahleh

Theses and Dissertations

The last-mile delivery option has become a focal point of academic research and industrial development in recent years. Multiple factors such as increased demands on delivery flexibility, customer requirements, delivery urgency, and many others are enforcing to adopt this option. For fulfilling this paradigm shift in delivery and providing additional flexibility, drones can be considered as a viable option to use for last-mile delivery cases. Numerous drones are available in the market with varying capacities and functionalities, posing a significant challenge for decision-makers to select the most appropriate drone type for a specific application. For this purpose, this study proposes …

Supplier Performance Scorecard Utilization In The Medical Device Manufacturing Healthcare Supply Chain, Justin Cardisco

Theses and Dissertations

The medical device manufacturing industry has a deficiency in determining how to improve supplier performance for the components and systems they purchase. Many complex medical devices require components from superb suppliers. But how does a medical device manufacturer (MDM) impartially assess supplier performance to know which suppliers to continuing with (or even boost purchase volumes) and which suppliers they should exit? This study describes which supplier-specific metrics are most important to medical device manufacturers (MDMs) so they can utilize this supplier performance scorecard backed by real-world inputs. This research will focus on five categories to measure MDM supplier performance (Quality, …

An Optimization Modeling Framework To Evaluate Civilians Response Under Active Shooter Violence Situations, Joseph G. Kerlin

Theses and Dissertations

Workplace safety is under serious threat due to the increasing trend of active shooter violence in recent years. Therefore, it becomes essential that the safety of a workplace is rigorously and, most importantly, methodologically assessed against active shooter violence. To serve this purpose, this study proposes a machine learning-optimization framework to assess the safety of a building against possible active shooter violence. First, several state-of-the-art machine learning models are employed to predict an agent’s movement decisions (with directions) under different violence scenarios. The predictions are then utilized in a mixed-integer linear programming model to maximize the agent’s utility under a …

Center For Manufacturing Excellence Capstone Project: Sec Rivals Checkers, Ward Winstead

Honors Theses

Each year, the seniors in the Haley Barbour Center for Manufacturing Excellence complete a capstone project. A team comprised of seniors in varying disciplines work to develop a business model focused on producing a specific product. This team, SEC Rivals Checkers, chose to produce wooden checker boards where each half of a board is custom to a specific SEC school. These halves were designed to be interchangeable, so a variety of different combination could be created when utilizing the product. Through initial marketing analysis, cost estimation, prototyping, and process development, the original SEC Rivals Checkers idea was developed into a …

In-Vivo Damage Development In Vena Cava Filter: Study Of A Retrieved Device, Anne Marie Lutz, Tarun Goswami

Biomedical, Industrial & Human Factors Engineering Faculty Publications

This article was prepared from a project assigned in a graduate class, BME 7371, Failure Assessment of Medical Devices, taught at Wright State University by the senior author. The device was donated for the study which was successfully retrieved after 93 days in-vivo. Even-though the mechanical integrity of the device held in-tact, the microscopic observations revealed that the damage via corrosion and scratching took place on the surface of the device. The image reconstructed in 3D using image-J software to determine device roughness and depth-of-pits. Results presented in this paper show that damage starts developing in these devices after the …

Mechanical Properties Of Nanoparticles In The Drug Delivery Kinetics, Kaivon Assani, Amy Neidhard-Doll, Tarun Goswami

Biomedical, Industrial & Human Factors Engineering Faculty Publications

Nanoparticle formulation is a recently developed drug delivery technology with enhanced targeting potential. Nanoparticles encapsulate the drug of choice and delivers it to the target via a targeting molecules (ex. antigen) located on the nanoparticle surface. Nanoparticles can even be targeted to deeply penetrating tissue and can be modeled to deliver drugs through the blood brain barrier. These advancements are providing better disease targeting such as to cancer and Alzheimer’s. Various polymers can be manufactured into nanoparticles. The polymers examined in this paper are polycaprolactone (PCL), poly(lactic acid) (PLA), poly(lactic-co-glycolic acid) (PLGA), and poly(glycolic acid) (PGA). The purpose of this …

A Spatiotemporal Analysis Of Food Pantry Accessibility In Washington County, Arkansas, Coleman Warren

Industrial Engineering Undergraduate Honors Theses

Food pantries are an essential resource for impoverished and food insecure communities. Washington County, Arkansas has a food insecurity rate of 14.3% as compared to the national average of 10.9% (Feeding America, 2019). The Northwest Arkansas Food Bank has a robust pantry network in Washington County to support families and individuals who struggle with food insecurity.

We conducted a spatiotemporal analysis of food pantry accessibility in Washington County, Arkansas to evaluate the effectiveness of the food pantry network in Washington County at supporting communities with the most need. This analysis was conducted using the Two-Step Floating Catchment Area (2SFCA) method …

Assessing The Influence Of Health Policy And Population Mobility On Covid-19 Spread In Arkansas, Tayden Barretto

Industrial Engineering Undergraduate Honors Theses

The outbreak of COVID-19 has created a major crisis across the world since its start in 2019, and its influence on every realm of society is undeniable. Globally, more than 500 million cases have been recorded since March 2020, with almost 6 million deaths. In the wake of this crisis, many governments and health organizations have taken steps and precautions to mitigate its spread. These steps involve public mandates of information, reducing frequency of personal contact, and use of masks to minimize the risk of transmission. Current access to mobility data released from Google detailing population movements has provided a …

Analyzing Vulnerabilities In The Northwest Arkansas Highway Network Using Mathematical Optimization, Brandon Jerome

Industrial Engineering Undergraduate Honors Theses

The highway and bridge network is a critical infrastructure that allows for the free transportation of citizens and enables truck-borne freight transportation. Disruption of this system could be caused by a terrorist attack, natural disaster, growth of population, required repairs and upgrades, or collapse caused by old age or malfunction. In the event of a disruption cities and regions can experience increased traffic and supply chain shortages, thus causing cascading effects throughout surrounding areas. With this motivation, we develop a network interdiction optimization model to identify a limited subset of roads that, if disrupted, causes the greatest increase in the …

Interdiction Models To Disrupt The Operations Of Sex Trafficking And Other Forced Illicit Labor Networks, Michael T. Clark

All Theses

Sex traffickers often force their victims to work in both commercial sex markets and perform other illicit activities (e.g., drug dealing, theft, and fraud). Current literature has failed to address interdiction models that aim to disrupt all components of a sex traffickers’ operation, including these other illicit activities. In this thesis, we present a interdiction problem, and its single-level linear optimization reformulation, to reduce the profit of a human trafficking network concurrently operating in the commercial sex market and other illicit activity markets. Our novel formulation aims to investigate the practical implications of interdiction decisions made to disrupt a human …

Implementing The Cms+ Sports Rankings Algorithm In A Javafx Environment, Luke Welch

Industrial Engineering Undergraduate Honors Theses

Every year, sports teams and athletes get cut from championship opportunities because of their rank. While this reality is easier to swallow if a team or athlete is distant from the cut, it is much harder when they are right on the edge. Many times, it leaves fans and athletes wondering, “Why wasn’t I ranked higher? What factors when into the ranking? Are the rankings based on opinion alone?” These are fair questions that deserve an answer. Many times, sports rankings are derived from opinion polls. Other times, they are derived from a combination of opinion polls and measured performance. …

Academic Advising Support Tool: An Optimization Approach, Spencer Loper

Industrial Engineering Undergraduate Honors Theses

More than ever, a college education is necessary to remain competitive in the job market. Therefore, colleges are dedicating numerous resources to ensure student success. Nonetheless, one of the most important factors of student success is proper academic advising. Students at the University of Arkansas and more specifically within the department of Industrial Engineering department are fortunate to have access to fantastic advising. However, given the volume of students, academic advisors do not have the time to talk through the nuance of every student’s long-term academic plan. The department does provide an eight-semester plan; however, students who have deviated from …

Selected Interdiction Games With Uncertain, Risk-Averse, And Simultaneous Play Considerations, Di H. Nguyen

All Dissertations

This dissertation examines two network interdiction problems: a shortest-path interdiction problem under uncertainty and a network interdiction problem in a simultaneous game. Both problems happen in two stages over a directed network, and involve a leader and a follower who have opposing interests.

In the first problem, the leader acts first to lengthen a subset of arcs, and a follower acts second to select a shortest path across the network. The cost for a follower’s arc consists of a base cost if the arc is not interdicted, plus an additional cost that is incurred if the arc is interdicted. The …

Design And Analysis Of Efficient Freight Transportation Networks In A Collaborative Logistics Environment, Vishal Badyal

All Dissertations

The increase in total freight volumes, reducing volume per freight unit, and delivery deadlines have increased the burden on freight transportation systems of today. With the evolution of freight demand trends, there also needs to be an evolution in the freight distribution processes. Today's freight transportation processes have a lot of inefficiencies that could be streamlined, thus preventing concerns like increased operational costs, road congestion, and environmental degradation. Collaborative logistics is one of the approaches where supply chain partners collaborate horizontally or/and vertically to create a centralized network that is more efficient and serves towards a common goal or objective. …

Comparing Actively Managed Mutual Fund Categories To Index Funds Using Linear Regression Forecasting And Portfolio Optimization, Luke Weiner

Industrial Engineering Undergraduate Honors Theses

The global investment industry offers a wide variety of investment products especially for individual investors. One such product, index funds, which are younger than actively managed mutual funds, have typically outperformed managed funds. Despite this phenomenon, investors have displayed a tendency to continue investing in actively managed funds. Although only a small percentage of actively managed funds outperform index funds, the costs of actively managed funds are significantly higher. Also, managed fund performances are most often determined by their fund category such as growth or real estate. I wanted to answer the following question for individual investors: can we …

Investigations Of External Resources And The Impact Of Imaging On Patient Flow In The Emergency Department, Marisa Shehan

All Theses

The problems associated with Emergency Department (ED) crowding are numerous, varied, and complex. Though overcrowded Emergency Departments are frequently attributed to overcrowded hospitals, crowding is also impacted by bottlenecks in patient flow. While discrete-event simulation (DES) is commonly used to model ED flow, external resources are typically excluded from these models due to their complexity and the limited amount of known information for these processes. Instead, external resources such as consults, labs, and imaging are modeled using estimation and/or educated guesswork. In this study, the impact of imaging on patient flow was assessed through data analysis of specific imaging factors, …

Deep Learning Object-Based Detection Of Manufacturing Defects In X-Ray Inspection Imaging, Juan C. Parducci

Mechanical & Aerospace Engineering Theses & Dissertations

Current analysis of manufacturing defects in the production of rims and tires via x-ray inspection at an industry partner’s manufacturing plant requires that a quality control specialist visually inspect radiographic images for defects of varying sizes. For each sample, twelve radiographs are taken within 35 seconds. Some defects are very small in size and difficult to see (e.g., pinholes) whereas others are large and easily identifiable. Implementing this quality control practice across all products in its human-effort driven state is not feasible given the time constraint present for analysis.

This study aims to identify and develop an object detector capable …

Forecasting Hypotension By Learning From Multivariate Mixed Responses.., Jodie Ritter

Electronic Theses and Dissertations

Blood Pressure is the main determinant of blood flow to organs. Hypotension is defined as a systolic blood pressure less than 90 mmHg or a diastolic blood pressure less than 50 mmHg. The severity and duration of hypotension is associated with low blood flow to organs often result in organ damage and a high mortality rate. Predicting hypotension prior to surgery and during the surgery can reduce the incidence and duration resulting in better patient outcomes. This thesis uses preoperative bloodwork and vital signs as well as perioperative vital signs in 5-minute increments as inputs to forecast hypotension. Hypotension can …