Industrial Engineering Commons^™

Therapeutic Efficacies Of Nano Carriers In Delivering Drugs, Bailey Krueger, Taylor Frazier, Sheila Galbreath, Tarun Goswami

Biomedical, Industrial & Human Factors Engineering Faculty Publications

The drug release rates of poorly soluble medications such as doxorubicin has been investigated in this paper. Since the drug was fixed, different carriers used to deliver it and their release rates compiled from literature were evaluated in this paper. Even though targeting of drugs is very important in drug delivery, it is not within the scope of this paper. However, functionalization of the carrier may provide this benefit, those constructs are included for comparison in terms of hybrid constructs. Dendrimer, micelles and hybrid constructs used in the delivery of doxorubicin compared in this paper with respect to carrier size …

A Survey Of Smart Manufacturing For High-Mix Low-Volume Production In Defense And Aerospace Industries, Tanjida Tahmina, Mauro Garcia, Zhaohui Geng, Bopaya Bidanda

Manufacturing & Industrial Engineering Faculty Publications

Defense and aerospace industries usually possess unique high-mix low-volume production characteristics. This uniqueness generally calls for prohibitive production costs and long production lead-time. One of the major trends in advanced, smart manufacturing is to be more responsive and better readiness while ensuring the same or higher production quality and lower cost. This study reviews the state-of-the-art manufacturing technologies to solve these issues and previews two levels of flexibility, i.e., system and process, that could potentially reduce the costs while increasing the production volume in such a scenario. The main contribution of the work includes an assessment of the current solutions …

Safe Zones In Hip-Implant Designs To Resist Dislocation, Himanshu Bhatt, Tarun Goswami

Biomedical, Industrial & Human Factors Engineering Faculty Publications

Major contributing parameters to hip implant dislocation include preoperative, intra-operative and post-operative factors. Implant geometry are design as well as non-design related. Femoral and acetabular component design features causing dislocation and/or resisting it are elucidated. Twelve implants were designed during this investigation were analyzed for dislocation resistance. A safe zone, establishes combinations of implant dimensions, was analyzed for all the 12 implants where implants were dislocation resistant. Head diameters between 26 mm to 32 mm, neck diameters closer to 14 mm, and neck angle between 25 to 35º were examined to be the safest ranges for hip implant designs.

Study Of Stochastic Market Clearing Problems In Power Systems With High Renewable Integration, Saumya Sakitha Sashrika Ariyarathne

Operations Research and Engineering Management Theses and Dissertations

Integrating large-scale renewable energy resources into the power grid poses several operational and economic problems due to their inherently stochastic nature. The lack of predictability of renewable outputs deteriorates the power grid’s reliability. The power system operators have recognized this need to account for uncertainty in making operational decisions and forming electricity pricing. In this regard, this dissertation studies three aspects that aid large-scale renewable integration into power systems. 1. We develop a nonparametric change point-based statistical model to generate scenarios that accurately capture the renewable generation stochastic processes; 2. We design new pricing mechanisms derived from alternative stochastic programming …

Exploring The Effects Of Meaningful Tactile Display On Perception And Preference In Automated Vehicles, Kimberly D. Martinez, Gaojian Huang

Mineta Transportation Institute

There is an existing issue in human-machine interaction, such that drivers of semi-autonomous vehicles are still required to take over control of the vehicle during system limitations. A possible solution may lie in tactile displays, which can present status, direction, and position information while avoiding sensory (e.g., visual and auditory) channels overload to reliably help drivers make timely decisions and execute actions to successfully take over. However, limited work has investigated the effects of meaningful tactile signals on takeover performance. This study synthesizes literature investigating the effects of tactile displays on takeover performance in automated vehicles and conducts a human-subject …

Analysis Of A Queueing Model With Map Arrivals And Heterogeneous Phase-Type Group Services, Srinivas R. Chakravarthy

Industrial & Manufacturing Engineering Publications

Queueing models have proven to be very useful in real-life applications to enable the practitioners to optimize the limited resources to conduct their businesses as well as offer services efficiently. In general, we can group such applications into two sectors: manufacturing and service. These two sectors cover everything we deal with on a day-to-day basis. Queues in which the services are offered in blocks (or groups or batches) are well established in the literature and have a wide variety of applications in practice. In this paper, we look at one such queueing model in which the arrivals occur according to …

Synthesizing And Printing Of Tin Oxide Nanoparticles Using A Single Ultrafast Laser System: A Feasibility Study, Enrique Contreras Lopez, Farid Ahmed, Jianzhi Li

Manufacturing & Industrial Engineering Faculty Publications

In laser-based manufacturing, processing setup customization is one of the popular approaches used to enhance diversity in material processing using a single laser. In this study, we propose setup design modification of an ultrafast laser system to demonstrate both Tin Oxide (SnO2) nanoparticle synthesis from bulk metal, and post printing of said nanoparticles using Laser Induced Forward Transfer (LIFT) method. Using the Pulse Laser Ablation in Liquid (PLA-L) method, nanoparticles were synthesized from a bulk tin metal cube submerged in distilled water. Such nanoparticles dispersed in water can form colloidal ink that can be used for different printed electronics applications. …

A Numerical Study On The Powder Flowability, Spreadability, Packing Fraction In Powder Bed Additive Manufacturing, Yeasir Mohammad Akib, Ehsan Marzbanrad, Farid Ahmed, Jianzhi Li

Manufacturing & Industrial Engineering Faculty Publications

The powder bed fusion (PBF) process is widely adopted in many manufacturing industries because of its capability to 3D print complex parts with micro-scale precision. In PBF process, a thermal energy source is used to selectively fuse powder particles layer by layer to build a part. The build quality in the PBF process primarily depends on the thermal energy deposition and properties of the powder bed. Powder flowability, powder spreading, and packing fraction are key factors that determine the properties of a powder bed. Therefore, the study of these process parameters is essential to better understand the PBF process. In …

Ultrafast Laser Direct Writing Of Conductive Patterns On Polyimide Substrate, Ishrat Jahan Biswas, Enrique Contreras Lopez, Farid Ahmed, Jianzhi Li

Manufacturing & Industrial Engineering Faculty Publications

Laser direct writing (LDW) is a fast and cost-effective method for printing conductive patterns in flexible polymer substrates. The electrical, chemical, and mechanical properties of polyimide (PI) make it an attractive material choice for laser writing of conductive circuits in such polymer. Electrically insulating PI has shown great potential for flexible printed electronics as LDW enables selective carbonization in the bulk of such material leading to the formation of conductive lines. However, existing studies in this area reveal a few key limitations of this approach including limited conductivity of written structures and fragility of carbonized PI. Therefore, more research is …

Turning Of Carbon Fiber Reinforced Polymer (Cfrp) Composites: Process Modeling And Optimization Using Taguchi Analysis And Multi-Objective Genetic Algorithm, S. M. Abdur Rob, Anil K. Srivastava

Manufacturing & Industrial Engineering Faculty Publications

Carbon Fiber Reinforced Polymer (CFRP) composites have been widely used in aerospace, automotive, nuclear, and biomedical industries due to their high strength-to-weight ratio, corrosion resistance, durability, and excellent thermo-mechanical properties in non-oxidative atmospheres. Machining of CFRP composites has always been a challenge for manufacturers. In this research, a comparative study was performed between the optimal machining parameters of coated and uncoated carbide inserts obtained from the Multi-Objective Genetic Algorithm during turning of CFRP composites. It was found that coated carbide inserts provide lower tool wear and surface roughness, but higher cutting forces compared to those of uncoated carbide inserts …

Automated Posture Positioning For High Precision 3d Scanning Of A Freeform Design Using Bayesian Optimization, Zhaohui Geng, Bopaya Bidanda

Manufacturing & Industrial Engineering Faculty Publications

Three-dimensional scanning is widely used for the dimension measurements of physical objects with freeform designs. The output point cloud is flexible enough to provide a detailed geometric description for these objects. However, geometric accuracy and precision are still debatable for this scanning process. Uncertainties are ubiquitous in geometric measurement due to many physical factors. One potential factor is the object’s posture in the scanning region. The posture of target positioning on the scanning platform could influence the normal of the scanning points, which could further affect the measurement variances. This paper first investigates the geometric and spatial factors that could …

Minimax Registration For Point Cloud Alignment, Zhaohui Geng, Mauro Garcia, Bopaya Bidanda

Manufacturing & Industrial Engineering Faculty Publications

The alignment, or rigid registration, of three-dimensional (3D) point clouds plays an important role in many applications, such as robotics and computer vision. Recently, with the improvement in high precision and automated 3D scanners, the registration algorithm has become critical in a manufacturing setting for tolerance analysis, quality inspection, or reverse engineering purposes. Most of the currently developed registration algorithms focus on aligning the point clouds by minimizing the average squared deviations. However, in manufacturing practices, especially those involving the assembly of multiple parts, an envelope principle is widely used, which is based on minimax criteria. Our present work …

Ultrafast Laser Ablation Of Inconel 718 For Surface Improvement, Sampson Canacoo, Enrique Contreras Lopez, Oscar Coronel, Farid Ahmed, Jianzhi Li, Anil K. Srivastava

Manufacturing & Industrial Engineering Faculty Publications

Inconel 718 is considered difficult to machine because of its ability to maintain its properties at high temperatures. The low thermal conductivity of the alloy causes accelerated tool deterioration when machining. Selective laser melting (SLM) additive manufacturing introduces a possibility of eliminating these difficulties, and producing complex shapes with this difficult-to-machine material. However, high surface roughness and porosity usually occur at the surface of components produced through additive manufacturing. In this study, the surfaces of Inconel 718 samples produced through selective laser melting were treated using laser ablation. The process parameters for the laser ablation process were analyzed in …

Computation Of Risk Measures In Finance And Parallel Real-Time Scheduling, Yajuan Li

Dissertations

Many application areas employ various risk measures, such as a quantile, to assess risks. For example, in finance, risk managers employ a quantile to help determine appropriate levels of capital needed to be able to absorb (with high probability) large unexpected losses in credit portfolios comprising loans, bonds, and other financial instruments subject to default. This dissertation discusses the computation of risk measures in finance and parallel real-time scheduling.

Firstly, two estimation approaches are compared for one risk measure, a quantile, via randomized quasi-Monte Carlo (RQMC) in an asymptotic setting where the number of randomizations for RQMC grows large, but …

Optimizing Incentives For Systems With Heterogeneous Agents, Chen Chen

Dissertations

This dissertation explores new models and applications based on the game theory of incentives. This exploration starts with controlling an invasive insect problem to address one of the most significant challenges facing our forests, the invasion of the Emerald ash borer (EAB), a non-native, wood-boring insect that threatens to kill most ash trees in North America, through designing two new cost-sharing programs between the landowners and local governments. Ash trees are one of North America’s most widely distributed tree genera and a vital part of the green infrastructure of cities, where they provide residents with numerous social, economic, and ecological …

Evaluating Safety And Productivity Relationship In Human-Robot Collaboration, Aayush Jain, Shakra Mehak, Philip Long, John D. Kelleher, Michael Guilfoyle, Maria Chiara Leva

Conference papers

Collaborative robots can improve ergonomics on factory floors while allowing a higher level of flexibility in production. The evolution of robotics and cyber-physical systems in size and functionality has enabled new applications which were never foreseen in traditional industrial robots. However, the current human-robot collaboration (HRC) technologies are limited in reliability and safety, which are vital in risk-critical scenarios. Certainly, confusion about European safety regulations has led to situations where collaborative robots operate behind security barriers, thus negating their advantages while reducing overall application productivity. Despite recent advances, developing a safe collaborative robotic system for performing complex industrial or daily …

Artificial Neural Networks And Gradient Boosted Machines Used For Regression To Evaluate Gasification Processes: A Review, Owen Sedej, Eric Mbonimpa, Trevor Sleight, Jeremy M. Slagley

Faculty Publications

Waste-to-Energy technologies have the potential to dramatically improve both the natural and human environment. One type of waste-to-energy technology that has been successful is gasification. There are numerous types of gasification processes and in order to drive understanding and the optimization of these systems, traditional approaches like computational fluid dynamics software have been utilized to model these systems. The modern advent of machine learning models has allowed for accurate and computationally efficient predictions for gasification systems that are informed by numerous experimental and numerical solutions. Two types of machine learning models that have been widely used to solve for quantitative …

Bayesian Network Development For Depots Location Selection With Biomass Supply System Excellence, Alaa Ashraf Abulhamail

Theses and Dissertations

The renewable energy of the wood pellet market has taken great attention over the last few periods. However, the returns from the pellet business depend largely on how well the quality of biomass. The objective is to economically harvest pellets matching pellet standards set forward by the U.S. markets. The single-mindedness of this study is to develop a Bayesian network model to ensure a high-quality flow through the supply chain of the pallet industry in the top ten counties in Mississippi state. Multiple critical decisions (harvesting, storage, transportation, and quality control) of a biomass-to-pellet supply system could potentially affect the …

A Biomechanical Approach To Prevent Falls In Ergonomic Settings, Sachini Kodithuwakku Arachchige

Theses and Dissertations

Introduction: Fall-related injuries are exceptionally prevalent in occupational settings. While endangering the workers’ health, falls cause poor productivity and increased economic burden in the workplace. Hence, identifying these threats and training workers to achieve proper postural control is crucial. Purpose: Study 1: To investigate the ankle joint kinematics in unexpected and expected trip responses during single-tasking (ST), dual-tasking (DT), and triple-tasking (TT), before and after a physically fatiguing exercise. Study 2: To investigate the impact of virtual heights, DT, and training on static postural stability and cognitive processing. Methods: Study 1: Twenty collegiate volunteers (10 males and females, one left …

Assessing Readiness For Implementation Of Prognostics And Health Management In Small And Medium Enterprises, Sara C. Fuller

Theses and Dissertations

Prognostics and Health Management (PHM) refers to using robust sensing, monitoring, and control to detect, assess, and track system health degradation and failure modes, allowing for enhanced management and operational decisions. The need for PHM within a manufacturing facility has increased due to a variety of reasons, such as the increasing complexity of manufacturing equipment.

A lack of readiness for digital implementations is linked to failure. The literature highlights certain barriers and enablers that can signal whether a technology implementation will be successful, such as management and maintenance employees’ desire to change the existing process, an understanding and willingness to …