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Distinct And Shared Determinants Of Cardiomyocyte Contractility In Multi-Lineage Competent Ethnically Diverse Human Ipscs, Martin L. Tomov, Zachary T. Olmsted, Haluk Dogan, Eda Gongorurler, Maria Tsompana, Hasan H. Otu, Michael Buck, Eun-Ah Chang, Jose Cibelli, Janet L. Paluh 2016 State University of New York Polytechnic Institute

Distinct And Shared Determinants Of Cardiomyocyte Contractility In Multi-Lineage Competent Ethnically Diverse Human Ipscs, Martin L. Tomov, Zachary T. Olmsted, Haluk Dogan, Eda Gongorurler, Maria Tsompana, Hasan H. Otu, Michael Buck, Eun-Ah Chang, Jose Cibelli, Janet L. Paluh

Department of Electrical and Computer Engineering: Faculty Publications

The realization of personalized medicine through human induced pluripotent stem cell (iPSC) technology can be advanced by transcriptomics, epigenomics, and bioinformatics that inform on genetic pathways directing tissue development and function. When possible, population diversity should be included in new studies as resources become available. Previously we derived replicate iPSC lines of African American, Hispanic-Latino and Asian self-designated ethnically diverse (ED) origins with normal karyotype, verified teratoma formation, pluripotency biomarkers, and tri-lineage in vitro commitment. Here we perform bioinformatics of RNA-Seq and ChIP-seq pluripotency data sets for two replicate Asian and Hispanic-Latino ED-iPSC lines that reveal differences in generation of …


Recognizing Pain Using Novel Simulation Technology, Justin C. Grace 2016 University of Central Florida

Recognizing Pain Using Novel Simulation Technology, Justin C. Grace

Honors Undergraduate Theses

Effective pain management and time to treatment is essential in patient care. Despite scientific evidence supporting the need to treat pain and an emphasis on addressing pain as a priority, pain management continues to be an unresolved issue. As a member of the health care team, nurses are integral to optimal pain management. Currently, nursing schools have limited innovative or alternative methods for teaching pain assessment and management. Simulation in nursing education provides a unique opportunity to expose students to realistic patient situations and allow them to learn and make mistakes without causing harm. However, modern low- and high-fidelity simulation …


Probabilistic-Based Computing Transformation With Reconfigurable Logic Fabrics, Mohammed Alawad 2016 University of Central Florida

Probabilistic-Based Computing Transformation With Reconfigurable Logic Fabrics, Mohammed Alawad

Electronic Theses and Dissertations

Effectively tackling the upcoming "zettabytes" data explosion requires a huge quantum leap in our computing power and energy efficiency. However, with the Moore's law dwindling quickly, the physical limits of CMOS technology make it almost intractable to achieve high energy efficiency if the traditional "deterministic and precise" computing model still dominates. Worse, the upcoming data explosion mostly comprises statistics gleaned from uncertain, imperfect real-world environment. As such, the traditional computing means of first-principle modeling or explicit statistical modeling will very likely be ineffective to achieve flexibility, autonomy, and human interaction. The bottom line is clear: given where we are headed, …


Fast And De-Noise Support Vector Machine Training Method Based On Fuzzy Clustering Method For Large Real World Datasets, OMID NAGHASH ALMASI, MODJTABA ROUHANI 2016 TÜBİTAK

Fast And De-Noise Support Vector Machine Training Method Based On Fuzzy Clustering Method For Large Real World Datasets, Omid Naghash Almasi, Modjtaba Rouhani

Turkish Journal of Electrical Engineering and Computer Sciences

Classifying large and real-world datasets is a challenging problem in machine learning algorithms. Among the machine learning methods, the support vector machine (SVM) is a well-known approach with high generalization ability. Unfortunately, while the number of training data increases and the data contain noise, the performance of SVM significantly decreases. In this paper, a fast and de-noise two-stage method for training SVMs to deal with large, real-world datasets is proposed. In the first stage, data that contain noises or are suspected to be noisy are identified and eliminated from the genuine training dataset. The process of elimination and identification is …


A New Cmos Zc-Cdta Realization And Its Filter Applications, ERSİN ALAYBEYOĞLU, HULUSİ HAKAN KUNTMAN 2016 TÜBİTAK

A New Cmos Zc-Cdta Realization And Its Filter Applications, Ersi̇n Alaybeyoğlu, Hulusi̇ Hakan Kuntman

Turkish Journal of Electrical Engineering and Computer Sciences

The Z copy current differencing transconductance amplifier (ZC-CDTA) is a new current-mode active element that was introduced recently. ZC-CDTA is improved from the current differencing transconductance amplifier (CDTA) and has increased its universality. In the current study, a CMOS implementation of ZC-CDTA is proposed. The first stage of ZC-CDTA consists of a current differencing unit. The output stage consists of a dual output transconductance amplifier. Furthermore, a third-generation current conveyor is used to copy the Z terminal current instead of a classical current mirror. A fourth-order filter application employing ZC-CDTAs is given and simulation results are added. The ZC-CDTA-based filter …


Design And Implementation Of A Man-Overboard Emergency Discovery System Based On Wireless Sensor Networks, ABDULLAH SEVİN, CÜNEYT BAYILMIŞ, İSMAİL ERTÜRK, HÜSEYİN EKİZ, AHMET KARACA 2016 TÜBİTAK

Design And Implementation Of A Man-Overboard Emergency Discovery System Based On Wireless Sensor Networks, Abdullah Sevi̇n, Cüneyt Bayilmiş, İsmai̇l Ertürk, Hüseyi̇n Eki̇z, Ahmet Karaca

Turkish Journal of Electrical Engineering and Computer Sciences

Recently, wireless sensor networks (WSNs) have been widely employed in many different fields such as military, surveillance, health, agricultural, automation, and environmental monitoring. This paper presents a designed and implemented WSN-based man-overboard emergency discovery system, abbreviated as W-MEDS, that discovers the location of a person in emergency circumstances and runs an alarm system on a ship. The developed W-MEDS carries out a fast man-overboard (MOB) discovery and initiates the vital rescue procedure. It mainly consists of a WSN and a control and discovery system. When a MOB accident occurs, this situation is easily detected through the WSN nodes capable of …


Residential Electricity Pricing Using Time-Varying And Non-Time-Varying Scenarios: An Application Of Game Theory, NAJME KHALEGHIFAR, HAMID AMADEH, MOHAMMAD HOSEIN REZAEIAN KOOCHI 2016 TÜBİTAK

Residential Electricity Pricing Using Time-Varying And Non-Time-Varying Scenarios: An Application Of Game Theory, Najme Khaleghifar, Hamid Amadeh, Mohammad Hosein Rezaeian Koochi

Turkish Journal of Electrical Engineering and Computer Sciences

residential consumer and the power network. With the growth of power systems and the advent of new energy sources, such as solar energy, it seems to be more essential to investigate how the network and the consumer can interact with each other to achieve more financial benefits. To do that, a static game is defined considering the fact that there is a direct relationship between the amount of load shifted by the consumer and the incentive offered by the network. It is concluded that the Nash equilibrium of this game is when the consumer decides to cooperate with the network …


A Robust Undervoltage Load Shedding Scheme Against Voltage Instability, IMAN KAFFASHAN, SEYED MOHAMMAD TAGHI MIRALI MORTEZAEE, TURAJ AMRAEE 2016 TÜBİTAK

A Robust Undervoltage Load Shedding Scheme Against Voltage Instability, Iman Kaffashan, Seyed Mohammad Taghi Mirali Mortezaee, Turaj Amraee

Turkish Journal of Electrical Engineering and Computer Sciences

No abstract provided.


Predicting Acute Hypotensive Episode By Using Hybrid Features And A Neuro-Fuzzy Network, MARZIEH ABBASINIA, FARDAD FAROKHI, SHAHRAM JAVADI 2016 TÜBİTAK

Predicting Acute Hypotensive Episode By Using Hybrid Features And A Neuro-Fuzzy Network, Marzieh Abbasinia, Fardad Farokhi, Shahram Javadi

Turkish Journal of Electrical Engineering and Computer Sciences

This paper presents an approach for acute hypotensive episode (AHE) time series forecasting based on hybrid feature space and a neuro-fuzzy network. Prediction was accomplished through a combination of time domain and wavelet features by using six vital time series of each patient, obtained from MIMIC-II and available in the context of the Physionet-Computers in Cardiology 2009 Challenge. At first, statistical time domain features were used and then the wavelet coefficient was utilized for extracting time scale features. Further UTA feature selection was applied and 30 effective features were determined and achieved to predict AHE with 96.30 accuracy 1.5 h …


Energy Efficient Multiconstrained Optimization Using Hybrid Aco And Ga In Manet Routing, NIVETHA SENTHIL KUMARAN, ASOKAN RAMASAMY 2016 TÜBİTAK

Energy Efficient Multiconstrained Optimization Using Hybrid Aco And Ga In Manet Routing, Nivetha Senthil Kumaran, Asokan Ramasamy

Turkish Journal of Electrical Engineering and Computer Sciences

Nodes in mobile ad hoc networks (MANET) suffer from limited battery power and bandwidth. Particularly for real time multimedia communications through MANET, metrics like residual node energy, bandwidth, and end-to-end delay have major impacts. In MANET, designing a dynamic routing algorithm to satisfy quality of service (QoS) requirements is a challenging task. Additionally, multiconstrained QoS routing aims to optimize multiple QoS metrics while providing required network resources and is an admittedly complex problem. It has been proved to be NP-complete when a combination of additive, concave, and multiplicative metrics are considered. Hence, this problem can be solved using metaheuristic methods …


A Centralized Self-Adaptive Fault Tolerance Approach Based On Feedback Control For Multiagent Systems, ŞEBNEM BORA, OĞUZ DİKENELLİ 2016 TÜBİTAK

A Centralized Self-Adaptive Fault Tolerance Approach Based On Feedback Control For Multiagent Systems, Şebnem Bora, Oğuz Di̇kenelli̇

Turkish Journal of Electrical Engineering and Computer Sciences

Our research introduces a self-adaptive fault tolerance approach for multiagent systems that enables the system to avoid crash failures. It is a replication-based approach that exploits a feedback control loop and a proportional (P) controller within a replication infrastructure. Thus, we are able to both observe the agents' behaviors to estimate criticalities and determine the number of replicas in replica groups with respect to the agents' criticalities and the number of available resources. Thus, agents that are to be replicated and the numbers of replicas in replica groups are automatically and adaptively identified in dynamic environments. We implement this approach …


Exploring Deviant Hacker Networks (Dhm) On Social Media Platforms, Samer Al-khateeb, Kevin J. Conlan, Nitin Agarwal, Ibrahim Baggili, Frank Breitinger 2016 University of Arkansas, Little Rock

Exploring Deviant Hacker Networks (Dhm) On Social Media Platforms, Samer Al-Khateeb, Kevin J. Conlan, Nitin Agarwal, Ibrahim Baggili, Frank Breitinger

Journal of Digital Forensics, Security and Law

Online Social Networks (OSNs) have grown exponentially over the past decade. The initial use of social media for benign purposes (e.g., to socialize with friends, browse pictures and photographs, and communicate with family members overseas) has now transitioned to include malicious activities (e.g., cybercrime, cyberterrorism, and cyberwarfare). These nefarious uses of OSNs poses a significant threat to society, and thus requires research attention. In this exploratory work, we study activities of one deviant groups: hacker groups on social media, which we term Deviant Hacker Networks (DHN). We investigated the connection between different DHNs on Twitter: how they are connected, identified …


Personalized And Adaptive Semantic Information Filtering For Social Media, Pavan Kapanipathi 2016 Wright State University

Personalized And Adaptive Semantic Information Filtering For Social Media, Pavan Kapanipathi

Browse all Theses and Dissertations

Social media has experienced immense growth in recent times. These platforms are becoming increasingly common for information seeking and consumption, and as part of its growing popularity, information overload pose a significant challenge to users. For instance, Twitter alone generates around 500 million tweets per day and it is impractical for users to have to parse through such an enormous stream to find information that are interesting to them. This situation necessitates efficient personalized filtering mechanisms for users to consume relevant, interesting information from social media. Building a personalized filtering system involves understanding users' interests and utilizing these interests to …


Detecting Php-Based Cross-Site Scripting Vulnerabilities Using Static Program Analysis, Steven M. Kelbley 2016 Wright State University

Detecting Php-Based Cross-Site Scripting Vulnerabilities Using Static Program Analysis, Steven M. Kelbley

Browse all Theses and Dissertations

With the widespread adoption of dynamic web applications in recent years, a number of threats to the security of these applications have emerged as significant challenges for application developers. The security of developed applications has become a higher priority for both developers and their employers as cyber attacks become increasingly more prevalent and damaging. Some of the most used web application frameworks are written in PHP and have become major targets due to the large number of servers running these applications worldwide. A number of tools exist to evaluate PHP code for issues, however most of these applications are not …


Miniatured Inertial Motion And Position Tracking And Visualization Systems Using Android Wear Platform, Dhruvkumar Navinchandra Patel 2016 Wright State University

Miniatured Inertial Motion And Position Tracking And Visualization Systems Using Android Wear Platform, Dhruvkumar Navinchandra Patel

Browse all Theses and Dissertations

In this thesis, we have designed and developed a motion tracking and visualization system using the latest motion tracking sensory technologies. It is one of the enabling technologies for our novel visual-inertial odometer and human anatomy based 3D Locating, Mapping and Navigation system for endoscopy and drug delivery capsules used inside GI tract. In particular, we have: i) designed and completed a cloud-based sensory data collecting, processing and storage system to provide the reliable computing and storage platform; ii) explored different data processing methods to obtain improved-quality motion results from extremely noisy raw data, e.g., by using a low pass …


Emerging Adaptive Architectures For Biomolecular Computation, Matthew Fleetwood 2016 Portland State University

Emerging Adaptive Architectures For Biomolecular Computation, Matthew Fleetwood

Maseeh Summer Undergraduate Research Experience

The goal of this work is to explore applications of reservoir computing in biomolecular computation. Reservoir computing is a unique model for representing a mapping from one instance in time to a specific output. A neural network of randomly connected neurons is linked with a single output neuron or multiple output neurons. The output neurons are capable of mapping inputs to desired outputs using adaptable algorithms. This framework is investigated by using the Python programming language and object oriented design and programming. Neurons are created in programs by bundling information like input data and attributes of the network, which utilize …


High-Performance Computing For Drought Prediction, Henry Cooney 2016 Portland State University

High-Performance Computing For Drought Prediction, Henry Cooney

Maseeh Summer Undergraduate Research Experience

In recent decades, there has been considerable interest in using satellite soil moisture data to examine the global water-energy cycle and manage water resources. Current satellites are limited in their sensing depth, and can only directly measure top soil layers. Using a particle filter, this data may be fused with the output of a hydrologic simulation to improve simulation results, and characterize a hydrologic system at the watershed level. However, this approach increases computational requirements dramatically, and requires rethinking to accommodate data scaling and achieve good performance.

We present a detailed performance study of several alternative implementations of the hybrid …


G-Code Generation For Multi-Process 3d Printing, Callum Peter Bailey 2016 University of Texas at El Paso

G-Code Generation For Multi-Process 3d Printing, Callum Peter Bailey

Open Access Theses & Dissertations

Since the inception of stereolithography in the 1980s, interest in 3D printing has exploded, with desktop 3D printers now commercially accessible to the general public. In recent years, next-generation multifunctional technologies have been developed, which combine 3D printing with other technologies such as wire embedding, foil embedding, CNC machining, and robotic component placement, enabling complex parts to be made on a single multifunctional machine.

However, the complexity of these integrated processes exceeds the capabilities of established design tools. To this end, this Thesis aims to develop a multi-functional design solution that can automatically generate final control code for next-generation multifunctional …


Robots As Legal Metaphors, Ryan Calo 2016 University of Washington School of Law

Robots As Legal Metaphors, Ryan Calo

Articles

This Article looks at the specific role robots play in the judicial imagination. The law and technology literature is replete with examples of how the metaphors and analogies that courts select for emerging technology can be outcome determinative. Privacy law scholar Professor Daniel Solove argues convincingly, for instance, that George Orwell's Big Brother metaphor has come to dominate, and in ways limit, privacy law and policy in the United States. Even at a more specific, practical level, whether a judge sees email as more like a letter or a postcard will dictate the level of Fourth Amendment protection she is …


Computational Methods For Comparative Non-Coding Rna Analysis: From Secondary Structures To Tertiary Structures, Ping Ge 2016 University of Central Florida

Computational Methods For Comparative Non-Coding Rna Analysis: From Secondary Structures To Tertiary Structures, Ping Ge

Electronic Theses and Dissertations

Unlike message RNAs (mRNAs) whose information is encoded in the primary sequences, the cellular roles of non-coding RNAs (ncRNAs) originate from the structures. Therefore studying the structural conservation in ncRNAs is important to yield an in-depth understanding of their functionalities. In the past years, many computational methods have been proposed to analyze the common structural patterns in ncRNAs using comparative methods. However, the RNA structural comparison is not a trivial task, and the existing approaches still have numerous issues in efficiency and accuracy. In this dissertation, we will introduce a suite of novel computational tools that extend the classic models …


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