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Non-Parametric Combination Analysis Of Multiple Data Types Enables Detection Of Novel Regulatory Mechanisms In T Cells Of Multiple Sclerosis Patients., Sunjay Jude Fernandes, Hiromasa Morikawa, Ewoud Ewing, Sabrina Ruhrmann, Rubin Narayan Joshi, Vincenzo Lagani, Nestoras Karathanasis, Mohsen Khademi, Nuria Planell, Angelika Schmidt, Ioannis Tsamardinos, Tomas Olsson, Fredrik Piehl, Ingrid Kockum, Maja Jagodic, Jesper Tegnér, David Gomez-Cabrero 2019 Karolinska Institutet; Science for Life Laboratory

Non-Parametric Combination Analysis Of Multiple Data Types Enables Detection Of Novel Regulatory Mechanisms In T Cells Of Multiple Sclerosis Patients., Sunjay Jude Fernandes, Hiromasa Morikawa, Ewoud Ewing, Sabrina Ruhrmann, Rubin Narayan Joshi, Vincenzo Lagani, Nestoras Karathanasis, Mohsen Khademi, Nuria Planell, Angelika Schmidt, Ioannis Tsamardinos, Tomas Olsson, Fredrik Piehl, Ingrid Kockum, Maja Jagodic, Jesper Tegnér, David Gomez-Cabrero

Computational Medicine Center Faculty Papers

Multiple Sclerosis (MS) is an autoimmune disease of the central nervous system with prominent neurodegenerative components. The triggering and progression of MS is associated with transcriptional and epigenetic alterations in several tissues, including peripheral blood. The combined influence of transcriptional and epigenetic changes associated with MS has not been assessed in the same individuals. Here we generated paired transcriptomic (RNA-seq) and DNA methylation (Illumina 450 K array) profiles of CD4+ and CD8+ T cells (CD4, CD8), using clinically accessible blood from healthy donors and MS patients in the initial relapsing-remitting and subsequent secondary-progressive stage. By integrating the output of a …


Recent Trends, Current Research In Cyberpsychology: A Literature Review, Amarjit Kumar Singh, Pawan Kumar Singh 2019 Library Assistant, Central Library, Central University of South Bihar (CUSB), Gaya (Bihar)

Recent Trends, Current Research In Cyberpsychology: A Literature Review, Amarjit Kumar Singh, Pawan Kumar Singh

Library Philosophy and Practice (e-journal)

Cyberpsychology refers to the study of the mind and behavior in the context of interactions with technology. It is an emerging branch, which has focused on the psychological aspects connected to the increasing presence and usages of technology in modern lives. This paper traces recent advancement and trends of Cyberpsychology is an emerging domain of knowledge and goes on the give a literature review of the same. An analysis of the recent research and literature covering 300 most relevant research papers from the period of 2012 to 15, August 2019 was conducted to determine and shape the research pattern based …


A Tutorial On Detecting Security Attacks On Cyber-Physical Systems, Paul Griffioen, Sean Weerakkody, Bruno Sinopoli, Omur Ozel, Yilin Mo 2019 Dordt University

A Tutorial On Detecting Security Attacks On Cyber-Physical Systems, Paul Griffioen, Sean Weerakkody, Bruno Sinopoli, Omur Ozel, Yilin Mo

Faculty Work Comprehensive List

Cyber-physical systems (CPSs) have become targets for malicious adversaries, creating new challenges for attaining reliable CPS performance. Achieving CPS security requires tools which extend beyond what is offered in state of the art software and cyber security. In this tutorial, we consider a science of CPS security which combines tools from both cyber security and system theory to defend against adversarial behavior. We discuss realistic and intelligent attack models from an adversarial perspective and then present mechanisms for defenders to achieve resilience by recognizing and responding to such malicious behavior. The focus of this tutorial is particularly on the recognition …


Polarization Division Multiplexing For Optical Data Communications, Darko Ivanovich 2019 Washington University in St. Louis

Polarization Division Multiplexing For Optical Data Communications, Darko Ivanovich

McKelvey School of Engineering Graduate Student Theses & Dissertations

Multiple parallel channels are ubiquitous in optical communications, with spatial division multiplexing (separate physical paths) and wavelength division multiplexing (separate optical wavelengths) being the most common forms. In this research work, we investigate the viability of polarization division multiplexing, the separation of distinct parallel optical communication channels through the polarization properties of light. We investigate polarization division multiplexing based optical communication systems in five distinct parts. In the first part of the work, we define a simulation model of two or more linearly polarized optical signals (at different polarization angles) that are transmitted through a common medium (e.g., air), filtered …


Decoupling Information And Connectivity Via Information-Centric Transport, Hila Ben Abraham 2019 Washington University in St. Louis

Decoupling Information And Connectivity Via Information-Centric Transport, Hila Ben Abraham

McKelvey School of Engineering Graduate Student Theses & Dissertations

The power of Information-Centric Networking architectures (ICNs) lies in their abstraction for communication --- the request for named data. This abstraction was popularized by the HyperText Transfer Protocol (HTTP) as an application-layer abstraction, and was extended by ICNs to also serve as their network-layer abstraction. In recent years, network mechanisms for ICNs, such as scalable name-based forwarding, named-data routing and in-network caching, have been widely explored and researched. However, to the best of our knowledge, the impact of this network abstraction on ICN applications has not been explored or well understood. The motivation of this dissertation is to address this …


Knn Optimization For Multi-Dimensional Data, Arialdis Japa 2019 Kennesaw State University

Knn Optimization For Multi-Dimensional Data, Arialdis Japa

Master of Science in Computer Science Theses

The K-Nearest Neighbors (KNN) algorithm is a simple but powerful technique used in the field of data analytics. It uses a distance metric to identify existing samples in a dataset which are similar to a new sample. The new sample can then be classified via a class majority voting of its most similar samples, i.e. nearest neighbors. The KNN algorithm can be applied in many fields, such as recommender systems where it can be used to group related products or predict user preferences. In most cases, the performance of the KNN algorithm tends to suffer as the size of the …


Optimizing Impression Counts For Outdoor Advertising, Yipeng ZHANG, Yuchen LI, Zhifeng BAO, Songsong MO, Ping ZHANG 2019 Singapore Management University

Optimizing Impression Counts For Outdoor Advertising, Yipeng Zhang, Yuchen Li, Zhifeng Bao, Songsong Mo, Ping Zhang

Research Collection School Of Computing and Information Systems

In this paper we propose and study the problem of optimizing theinfluence of outdoor advertising (ad) when impression counts aretaken into consideration. Given a database U of billboards, each ofwhich has a location and a non-uniform cost, a trajectory databaseT and a budget B, it aims to find a set of billboards that has themaximum influence under the budget. In line with the advertisingconsumer behavior studies, we adopt the logistic function to takeinto account the impression counts of an ad (placed at differentbillboards) to a user trajectory when defining the influence measurement. However, this poses two challenges: (1) our problemis …


Coresets For Minimum Enclosing Balls Over Sliding Windows, Yanhao WANG, Yuchen LI, Kian-Lee TAN 2019 Singapore Management University

Coresets For Minimum Enclosing Balls Over Sliding Windows, Yanhao Wang, Yuchen Li, Kian-Lee Tan

Research Collection School Of Computing and Information Systems

Coresets are important tools to generate concise summaries of massive datasets for approximate analysis. A coreset is a small subset of points extracted from the original point set such that certain geometric properties are preserved with provable guarantees. This paper investigates the problem of maintaining a coreset to preserve the minimum enclosing ball (MEB) for a sliding window of points that are continuously updated in a data stream. Although the problem has been extensively studied in batch and append-only streaming settings, no efficient sliding-window solution is available yet. In this work, we first introduce an algorithm, called AOMEB, to build …


Subsurface Mimo: A Beamforming Design In Internet Of Underground Things For Digital Agriculture Applications, Abdul Salam 2019 Purdue University

Subsurface Mimo: A Beamforming Design In Internet Of Underground Things For Digital Agriculture Applications, Abdul Salam

Computer Information Technology Faculty Publications

In underground (UG) multiple-input and multiple-output (MIMO), the transmit beamforming is used to focus energy in the desired direction. There are three different paths in the underground soil medium through which the waves propagates to reach at the receiver. When the UG receiver receives a desired data stream only from the desired path, then the UG MIMO channel becomes three path (lateral, direct, and reflected) interference channel. Accordingly, the capacity region of the UG MIMO three path interference channel and degrees of freedom (multiplexing gain of this MIMO channel requires careful modeling). Therefore, expressions are required for the degree of …


Bleeding Out: The Case For Strengthening Healthcare Client Portal Data Privacy Regulations, Matthew D. McCord 2019 University of Minnesota Law School

Bleeding Out: The Case For Strengthening Healthcare Client Portal Data Privacy Regulations, Matthew D. Mccord

Minnesota Journal of Law, Science & Technology

No abstract provided.


Centralizing Energy Consumption Data In State Energy Data Centers, Zach Sibley 2019 University of Minnesota Law School

Centralizing Energy Consumption Data In State Energy Data Centers, Zach Sibley

Minnesota Journal of Law, Science & Technology

No abstract provided.


Guest Editorial Special Issue On Toward Securing Internet Of Connected Vehicles (Iov) From Virtual Vehicle Hijacking, Yue Cao, Houbing Song, Omprakash Kaiwartya, Sinem Coleri Ergen, Jaime Lloret, Naveed Ahmad 2019 Lancaster University

Guest Editorial Special Issue On Toward Securing Internet Of Connected Vehicles (Iov) From Virtual Vehicle Hijacking, Yue Cao, Houbing Song, Omprakash Kaiwartya, Sinem Coleri Ergen, Jaime Lloret, Naveed Ahmad

Publications

Today’s vehicles are no longer stand-alone transportation means, due to the advancements on vehicle-tovehicle (V2V) and vehicle-to-infrastructure (V2I) communications enabled to access the Internet via recent technologies in mobile communications, including WiFi, Bluetooth, 4G, and even 5G networks. The Internet of vehicles was aimed toward sustainable developments in transportation by enhancing safety and efficiency. The sensor-enabled intelligent automation of vehicles’ mechanical operations enhances safety in on-road traveling, and cooperative traffic information sharing in vehicular networks improves traveling efficiency.


Designing Cloud Computing Architecture For Bank Industry The Case Of Dashen Bank, Melaku Yenew 2019 Ambo University

Designing Cloud Computing Architecture For Bank Industry The Case Of Dashen Bank, Melaku Yenew

African Conference on Information Systems and Technology

Technology makes life easy. People contact banks in their day to day life activity. And also the banks are committed to serve their customers with the help of currently advanced technology. The aim of a bank is to give consistent and satisfactory banking services for the customers. The use of advanced technology in banking requires sophisticated knowledge of the technology and expertise and a large number of employees are required for implementation and management of that system.

Cloud computing makes easy the management of IT infrastructure and the bank sector systems. Cloud service providers provide three basic types of services: …


Model-Driven Engineering For Big Data, Belachew Regane 2019 Addis Ababa University

Model-Driven Engineering For Big Data, Belachew Regane

African Conference on Information Systems and Technology

Accessing heterogeneous and huge amount of data through different sources heavily impacts users of data nowadays worldwide. Thus, Big Data has now become a hot emerging paradigm in computing environments. Issues in scalability, interoperability, platform independency, adaptability and reusability in big data systems are considered the main current challenges. This raises the need for appropriate software engineering approaches to develop effective and efficient Big Data system models, i.e. an approach which reduce investment cost and development time. Today, software engineering has emerged advanced methodologies to solve problems from different perspectives, while still further research is needed to overcome new challenges …


A Study Of The Electron Regeneration Efficiency Of Solar Cells Fabricated Using Cmc/Pva-, Alginate-, And Xanthan-Based Electrolytes, Nur Farha Shaafi, Saifful Kamaluddin Muzakir, Bouchta Sahraoui 2019 Material Technology Program, Faculty of Industrial Sciences & Technology, Universiti Malaysia Pahang, Lebuhraya Tun Razak, Gambang 26300, Kuantan, Pahang, Malaysia

A Study Of The Electron Regeneration Efficiency Of Solar Cells Fabricated Using Cmc/Pva-, Alginate-, And Xanthan-Based Electrolytes, Nur Farha Shaafi, Saifful Kamaluddin Muzakir, Bouchta Sahraoui

Makara Journal of Technology

A photovoltaic (PV) mechanism consists of three important steps, i.e., (i) electron excitation upon absorption of photon with energy higher than the bandgap of fluorophore, (ii) excited-state electron injection from the fluorophore to the pho-toelectrode, and (iii) electron regeneration from the electrolyte to the fluorophore. An efficient electron regeneration could be achieved upon fulfillment of the requirements of energy alignment, i.e., lowest unoccupied molecular orbital of fluorophore (LUMOfluorophore) > redox potential of electrolyte > highest occupied molecular orbital of fluorophore (HOMOfluorophore). This study investigated the electron regeneration efficiency of excitonic solar cells fabricated using three polymer-based electrolytes, i.e., (i) 60% carboxymethyl cellulose …


Study Of Ecological Design Of Residential Complexes Using Spss To Elevate Resident Satisfaction, Soheil Malekpour Kolbadinejad, V. Malekpour Ravasjan, A. Darvish 2019 Department of Architecture, University of Marlik, Mazandaran 46134, Iran

Study Of Ecological Design Of Residential Complexes Using Spss To Elevate Resident Satisfaction, Soheil Malekpour Kolbadinejad, V. Malekpour Ravasjan, A. Darvish

Makara Journal of Technology

This article reports the general residential satisfaction, affecting ecological factors, and their importance in area in Tehran. The collected field data was analyzed using SPSS. Cronbach's alpha variable was used to determine the reliability of the questionnaire and the Friedman test was used to assess priorities that influence residential satisfaction. The results show that the quality of residential environments and general satisfaction of their residents may be enhanced by identifying these criteria and making appropriate plans for their improvement.


Adsorption Of Heavy Metal Ions By Oil Palm Decanter Cake Activated Carbon, Mohd. Ezreeza Mohamed Yusoff, Juferi Idris, Nahrul Hayawin Zainal, Mohamad Faizal Ibrahim, Suraini Abd-Aziz 2019 Department of Bioprocess Technology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia

Adsorption Of Heavy Metal Ions By Oil Palm Decanter Cake Activated Carbon, Mohd. Ezreeza Mohamed Yusoff, Juferi Idris, Nahrul Hayawin Zainal, Mohamad Faizal Ibrahim, Suraini Abd-Aziz

Makara Journal of Technology

Adsorption processes are widely used for the removal of heavy metals from waste streams. Oil palm decanter cake (OPDC) is used as a bioadsorbent because of its compositional properties for activated carbon production; moreover, it is a readily available raw material produced in palm oil mills and is thus abundant and cheap. In this study, the OPDC was carbonized at 700 °C and activated using steam at 700 °C to produce oil palm decanter cake activated carbon (AC-OPDC). Batch adsorption experiments were carried out to compare the adsorption capacities of the raw OPDC and the AC-OPDC for heavy metals removal. …


Use Of The “Dnachecker” Algorithm For Improving Bioinformatics Research, Nausheen Bhat, Ezra Bernadus Wijaya, Arli Aditya Parikesit 2019 Department of Bioinformatics, School of Life Sciences, Indonesia International Institute for Life Sciences, Jakarta Timur 13210, Indonesia

Use Of The “Dnachecker” Algorithm For Improving Bioinformatics Research, Nausheen Bhat, Ezra Bernadus Wijaya, Arli Aditya Parikesit

Makara Journal of Technology

Basic Local Alignment Sequencing Tool (BLAST) is a bioinformatics tool used for analyzing nucleotide sequences with regards to their similarity. BLAST can be found online on biological databases such as the National Center for Biotechnology Information (NCBI) and other such repositories. The mechanism of BLAST allows the target sequence to be compared with other sequences to find regions of local similarity, and thus, a comparability quotient that determines the resemblance between the sequences is created. Due to the open-platform nature of the online databanks, several sequences can be accepted with little to no interjections regarding the quality of sequence submitted. …


Component Analysis And Antiangiogenic Activity Of Thailand Stingless Bee Propolis, Eriko Ishizu, Sari Honda, Tosihro Ohta, Boonyadist Vongsak, Shigenori Kumazawa 2019 Department of Food and Nutritional Sciences, University of Shizuoka, Shizuoka 424-0414, Japan

Component Analysis And Antiangiogenic Activity Of Thailand Stingless Bee Propolis, Eriko Ishizu, Sari Honda, Tosihro Ohta, Boonyadist Vongsak, Shigenori Kumazawa

Makara Journal of Technology

Propolis is a natural resin produced by honey bees from certain plants, has gained popularity as a food and alternative medicine. However, to the best of our knowledge, few studies on native Thailand stingless bee propolis are available. Information on the chemical composition and biological activities of propolis is needed to investigate its potential utility. Recently we have reported the possible plant origin of Thailand stingless bee propolis, Garcinia mangostana. In this study, further component analysis, functional evaluation, and identification of the plant origin of Thailand stingless bee propolis are conducted. Nine xanthones, including α-mangostin, garcinone C, γ-mangostin, cochinchinone T, …


3d Fdtd Method For Modeling Of Seismo-Electromagnetics Disturbance On Crustal Earth, Nabila Husna Shabrina, Yasuhide Hobara, Achmad Munir 2019 Faculty of Engineering and Informatics, Universitas Multimedia Nusantara, Tangerang 15811, Indonesia

3d Fdtd Method For Modeling Of Seismo-Electromagnetics Disturbance On Crustal Earth, Nabila Husna Shabrina, Yasuhide Hobara, Achmad Munir

Makara Journal of Technology

The paper deals with the modelling of seismo-electromagnetics disturbance on the crustal earth by use of threedimensional (3D) finite-difference time-domain (FDTD) method. The model is built up by discretizing the frontier geographical region between Java Island and Sumatra Island in a cylindrical coordinate system-based 3D object. The proposed method is applied to compute and analyze electromagnetics (EM) fields of the observed very low frequency (VLF) wave used for the investigation. Boundary condition of uniaxial perfectly matched layer (UPML) are applied surrounding the area of computation for truncating the object of simulation. The investigation are focused on the propagation time of …


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