Therapeutic Plasma Exchange To Alleviate Ventricular Tachycardia After Diphenhydramine Ingestion,
2023
Children's Mercy Kansas City
Therapeutic Plasma Exchange To Alleviate Ventricular Tachycardia After Diphenhydramine Ingestion, Kaushal Dosani, Lejla Music Aplenc, Stephen Pfeiffer
Research Days
Background: The Covid-19 pandemic has adversely affected the mental health of children causing an increased incidence of suicide attempts. Diphenhydramine is a common household medication and is frequently ingested by children. Toxic doses of diphenhydramine can affect the cardiovascular and central nervous system. In the heart, diphenhydramine blocks fast sodium channels and potassium channels which can result in conduction abnormalities including sinus tachycardia, widening of QRS duration, ventricular tachycardia and torsades de pointes. Massive ingestion can cause severe cardiovascular collapse which may require ECMO support
Objectives/Goal: To describe a novel method of clearing highly protein-bound diphenhydramine molecules from circulation after …
Genes Predictive Of Aggressive Infant Acute Lymphoblastic Leukemia,
2023
Children's Mercy Kansas City
Genes Predictive Of Aggressive Infant Acute Lymphoblastic Leukemia, Meghana Bhumireddy
Research Days
Background: Acute Lymphoblastic Leukemia (ALL) is a rapidly progressive cancer in which the bone marrow makes too many immature leukocytes that divide uncontrollably. KMT2A, or MLL, is a methyltransferase found in many types of leukemia, whose rearrangement (KMT2A-r) is present in approximately 2/3 of infants with ALL. KMT2A-r is associated with a very poor prognosis: roughly ⅔ of patients relapse within 1 year of diagnosis, and the relapsed KMT2A-r ALL is resistant to treatment (having nearly 100% morality). We explored gene expression in patient samples from three groups at diagnosis: KMT2A-r patients who relapsed, KMT2A-r patients who did not relapse, …
Drug Metabolizing Enzymes And Transporters May Help Determineeffective Budesonide Dosing In Eoe,
2023
Children's Mercy Kansas City
Drug Metabolizing Enzymes And Transporters May Help Determineeffective Budesonide Dosing In Eoe, Laurie Mccann, Lisa Harvey, Norah Almahbub, Wendy Y. Wang, Erin C. Boone, Janelle R. Noel-Macdonnell Phd, Rachel Chevalier
Research Days
Background: Eosinophilic esophagitis (EoE) is a chronic inflammatory disorder diagnosed in children with painful or difficult swallowing, vomiting, or poor weight gain. Current treatment models adopt a trial-and-error approach in regard EoE treatment, including restrictive elimination diets, proton pump inhibitors, and topical budesonide. This approach can delay effective treatment which increases risk of disease progression and increases medical costs to families for frequent clinic visits and endoscopy.
Objectives/Goal: The objective of this study is to determine the CYP3A5 genotype and expression of patients with eosinophilic esophagitis to discover which patients will respond to standard dosing of topical budesonide treatment (1, …
Degree Of Uncertainty In Reporting Imaging Findings For Necrotizing Enterocolitis: A Secondary Analysis From A Pilot Randomized Diagnostic Trial,
2023
Kansas City University
Degree Of Uncertainty In Reporting Imaging Findings For Necrotizing Enterocolitis: A Secondary Analysis From A Pilot Randomized Diagnostic Trial, Disa Rathore, Kira Bourrett, Sherwin S. Chan, Erin Opfer, Alain Cuna
Research Days
Background: Uncertainty in reporting of imaging findings for necrotizing enterocolitis (NEC) can be challenging for clinicians and result in ambiguity, miscommunication, and potential diagnostic errors. The degree to which uncertainty complicates diagnostic imaging for NEC has not been characterized.
Objective: To determine the degree of uncertainty in diagnostic imaging for NEC.
Methods: We conducted a retrospective study using data from a previously completed pilot diagnostic randomized clinical trial (RCT). The study population comprised of preterm infants with suspected NEC who were randomized to either standard imaging with abdominal radiographs (AXR) alone or experimental imaging with AXR + add-on bowel ultrasound …
Reevaluating Student Engagement: Exploring And Applying Alternative Assignments In Higher Education Undergraduate Applied Saxophone,
2023
James Madison University
Reevaluating Student Engagement: Exploring And Applying Alternative Assignments In Higher Education Undergraduate Applied Saxophone, Anthony S. Cincotta Ii
Dissertations, 2020-current
Undergraduate applied saxophone study revolves around the conservatory model. This inflexible model, often referred to as a master-apprentice relationship, can create an instructor-centric power dynamic which does not address the needs of the modern student. A classroom where the power lies so heavily with the instructor can stifle student engagement and can create a sense of disenfranchisement. In this setting, students have limited input on their assignment selections. While curricula have evolved with regards to being more culturally diverse, relevant, and inclusive, the approach that educators use to deliver the material has remained largely unchanged. There is limited research on …
Management Of Primary Spontaneous Pneumothorax In Children: A Single Institution Protocol Analysis,
2023
Children's Mercy Hospital
Management Of Primary Spontaneous Pneumothorax In Children: A Single Institution Protocol Analysis, Shai Stewart Md, James Fraser, Nelimar Cruz-Centeno, Derek Marlor, Rebecca M. Rentea, Pablo Aguayo, David Juang, Jason D. Fraser, Charles L. Snyder, Richard J. Hendrickson, Tolulope A. Oyetunji, Shawn D. St.Peter
Research Days
Background: Primary spontaneous pneumothorax (PSP) affects 3.4 per 100,000 children in the United States. Regardless of the initial management, additional procedures, and prolonged hospital length of stay (LOS) may occur. There is currently no consensus in the pediatric surgical community on the optimal management of these patients, which has resulted in marked variability in management. The Midwest Pediatric Surgery Consortium (MWPSC), of which our site is a participant, suggested a management algorithm to include simple aspiration upon presentation, and if this fails, VATS should be considered.
Objectives/Goal: The purpose of this study was to evaluate the outcomes of instituting a …
Toward A Social Justice Emphasis In Preservice Teachers’ Inquiries In Small Liberal Arts Contexts,
2023
Smith College
Toward A Social Justice Emphasis In Preservice Teachers’ Inquiries In Small Liberal Arts Contexts, Lucy Mule
Journal of Practitioner Research
Scholars underscore the need to study core features and outcomes of preservice teacher (PST) inquiry. This qualitative study identifies facilitation as a key feature, and a social justice inquiry stance as an important outcome. The author analyzed PST inquiry reports from a graduate-level course, noting that fewer than half of the reports were focused on social justice and, despite a weak program emphasis, PSTs were adopting this inquiry stance. Analysis of student feedback surveys and instructor notes revealed that providing clear and structured processes, consistent written feedback, and frequent meetings with facilitator and peers were effective facilitation strategies. Additional strategies …
Institutional Outcomes Of Blunt Liver & Splenic Injury In The Atomac Era,
2023
Children's Mercy Hospital
Institutional Outcomes Of Blunt Liver & Splenic Injury In The Atomac Era, Shai Stewart Md, James Fraser, Rebecca M. Rentea, Pablo Aguayo, David Juang, Jason D. Fraser, Charles L. Snyder, Richard J. Hendrickson, Shawn D. St.Peter, Tolulope A. Oyetunji
Research Days
Background: The Arizona-Texas-Oklahoma-Memphis-Arkansas Consortium (ATOMAC) practice management guideline (PMG) was created to standardize management of blunt liver or spleen injury (BLSI) across pediatric trauma centers. Evaluations of institutional outcomes after its adoption remain scarce. We describe our outcomes since PMG adoption at our institution.
Objectives/Goal: The purpose of this study was to assess patient outcomes and resource utilization after implementation of this protocol. We hypothesized there is no difference in length of stay (LOS) or complications regardless of grade of isolated injuries to the liver or spleen. In addition, there is limited guidance on the management of concurrent injuries to …
A Novel Approach For Laparoscopic Direct Inguinal Hernia Repair In Children,
2023
Children's Mercy Hospital
A Novel Approach For Laparoscopic Direct Inguinal Hernia Repair In Children, Shai Stewart Md, Charlene Dekonenko, Nelimar Cruz-Centeno, Derek Marlor, Jason D. Fraser
Research Days
Background: Inguinal hernia repair is one of the most common operations performed by pediatric surgeons, and the frequency of laparoscopy for repair is increasing. The vast majority of these are indirect hernias and therefore how to best repair a direct defect when seen during laparoscopy is still unknown. Simple high ligation of the hernia sac (as is done in an indirect hernia) does not repair the inguinal floor weakness/defect seen in a direct hernia.
Objectives/Goal: We therefore present a case of laparoscopic bilateral indirect and direct inguinal hernia repair, commonly known as pantaloon hernia, repaired without mesh and utilizing the …
Antibiotic Monotherapy Vs Dual-Drug Therapy In Perforated Appendicitis: Single Center Retrospective Review,
2023
Children's Mercy Hospital
Antibiotic Monotherapy Vs Dual-Drug Therapy In Perforated Appendicitis: Single Center Retrospective Review, Shai Stewart Md, Nelimar Cruz-Centeno, Derek Marlor, Dae H. Kim, Shawn D. St Peter, Tolulope A. Oyetunji Md Mph
Research Days
Background: The optimal antibiotic regimen in perforated appendicitis to reduce intraabdominal abscess (IAA) formation has not yet been agreed upon in the pediatric surgery community. We aimed to evaluate the outcomes of patients with perforated appendicitis when intravenous antibiotic monotherapy with Piperacillin-Tazobactam (PT) versus dual-drug therapy with Ceftriaxone and Metronidazole (CM) are administered. We hypothesized there is no difference in the rate of IAA formation with antibiotic monotherapy, as opposed to our once-daily dosed, institutional standard dual-drug therapy.
Objectives/Goal: The goal was to determine if our current management protocols for acute appendicitis were delivering the best possible results for our …
Wearing Two Different Hats In Partnership Work – Student Partner And A Researcher At Lahore University Of Management Services,
2023
Syed Ahsan Ali and Syed Maratib Ali School of Education
Wearing Two Different Hats In Partnership Work – Student Partner And A Researcher At Lahore University Of Management Services, Arslan Abdullah
Teaching and Learning Together in Higher Education
No abstract provided.
Challenges In Pedagogical Partnership Focused On An Urdu Language Course,
2023
Lahore University of Management Sciences
Challenges In Pedagogical Partnership Focused On An Urdu Language Course, Aneeqa Khalid
Teaching and Learning Together in Higher Education
No abstract provided.
Working With Students, Learning From Students Through A Special Programme In Science At National University Of Singapore,
2023
National University of Singapore
Working With Students, Learning From Students Through A Special Programme In Science At National University Of Singapore, Linda Sellou, Ryan Seow, Kellie S. H. Wong, Kellisa J. L. Goh
Teaching and Learning Together in Higher Education
No abstract provided.
Academic Coaching For The Development Of Transferable Skills Through Work-Based Learning In A Singapore University,
2023
Singapore Institute of Technology
Academic Coaching For The Development Of Transferable Skills Through Work-Based Learning In A Singapore University, Chee M. Ong
Teaching and Learning Together in Higher Education
No abstract provided.
Partnership In The Age Of Generative Artificial Intelligence,
2023
Nanyang Technological University
Partnership In The Age Of Generative Artificial Intelligence, Emmanuel Tan
Teaching and Learning Together in Higher Education
No abstract provided.
Reflecting On The Influence Of Involution To The Shaping Of Pedagogical Partnerships In Chinese Universities,
2023
University of Queensland
Reflecting On The Influence Of Involution To The Shaping Of Pedagogical Partnerships In Chinese Universities, Yifei Liang
Teaching and Learning Together in Higher Education
No abstract provided.
Exploring The Development Of Pedagogical Partnerships In Asian Contexts,
2023
Bryn Mawr College
Exploring The Development Of Pedagogical Partnerships In Asian Contexts, Alison Cook-Sather
Teaching and Learning Together in Higher Education
No abstract provided.
Percepción De Docentes En Integración De Herramientas Tecnológicas Utilizando El Modelo Picrat En Una Institución De Nivel Superior,
2023
Nova Southeastern University
Percepción De Docentes En Integración De Herramientas Tecnológicas Utilizando El Modelo Picrat En Una Institución De Nivel Superior, Marangely Perez Montalvo
Theses and Dissertations
Este estudio tuvo como propósito analizar la percepción de los profesores sobre el modelo de integración tecnológica PICRAT y cómo este evalúa los niveles de reemplazo, amplificación y transformación que se le realizan a las herramientas tecnológicas para lograr una interacción pasiva, interactiva y creativa con el estudiante durante el proceso de enseñanza y aprendizaje. Se utilizó un enfoque cuantitativo con un diseño transeccional no experimental con un alcance descriptivo y correlacional. La muestra estuvo compuesta por 23 profesores universitarios que imparten al menos un curso de manera remota en el nivel académico de maestría con especialidades en Ciencias de …
A Comparison Of Large Tbsa Scald Versus Flame Burns In Young Children,
2023
Children's Mercy Hospital
A Comparison Of Large Tbsa Scald Versus Flame Burns In Young Children, Ashley Daniel
Research Days
Background: It is generally accepted that of children with the same total body surface area of burns, those with flame burns seem to have longer lengths of stay and more complications than those with scald burns. Anecdotally we have seen the opposite to be true. Among a consortium of five US pediatric burn centers participating in the Pediatric Injury Quality Improvement Collaborative (PIQIC), young children with scald burns seem to experience disproportionately more frequent and severe complications compared to their older counterparts and compared to patients of a similar age with flame burns.
Objectives/Goal: In this multi-institutional study, we compared …
Relationship Between Rurality And Access To Care For Families Of Hospitalized Children,
2023
Children's Mercy Kansas City
Relationship Between Rurality And Access To Care For Families Of Hospitalized Children, Zoetta L. Mcloughlin Md
Research Days
Background: At Children’s Mercy Hospital, greater than 1 in 5 hospitalized children are from rural areas. Rural families often travel long distances for hospitalization at free-standing children’s hospitals, a median of 70 miles according to recent work. Rural families are more likely than non-rural families to experience financial insecurity, and these baseline hardships may be intensified during hospitalization due to out-of-pocket costs, lost work, inability to meet family needs, and removal from social support. However, little is known about the differences in healthcare access and resulting burdens between rural and non-rural families.
Objectives/Goal: To describe differences in demographics, health care …
