American Studies Commons^™

Disparities In Survival And Mortality Among Infants With Congenital Aortic, Pulmonary, And Tricuspid Valve Defects By Maternal Race/Ethnicity And Infant Sex, Colleen Conklin

USF Tampa Graduate Theses and Dissertations

Background: The etiology of congenital heart valve defects is not well understood; little is known about the risk factors that contribute to the survival and mortality outcomes of children with these defects.

Methods: Using data from the Texas Birth Defects Registry (TBDR) we conducted a retrospective cohort study of 2070 singleton infants with congenital aortic, pulmonary, or tricuspid valve atresia or stenosis born in Texas between January 1, 1996 and December 31, 2007 to Hispanic, Non-Hispanic (NH) black, and NH white women. TBDR data were death-to-birth matched by the Texas Vital Statistics Unit for deaths between January 1, 1996 and …

A Tale Of Two Kings: The Use Of King David In The Chronicle Of Pere Iii Of Catalonia, Marrissa Lynne Cook

USF Tampa Graduate Theses and Dissertations

Pere III of Catalonia (1319-1387) began his reign in 1336. As count-king, he reigned over Aragon, Catalonia, and Valencia. The Chronicle of Pere III of Catalonia covers the years 1319-1369, fifty years of a nearly seventy year life. Pere wrote this chronicle in collaboration with his chancery office. Bernat Descoll was the main contributor from the chancery, and he consulted with the king as he wrote it. The chronicle reflects spiritual justifications for actions that occurred during Pere's reign, such as his conflict with the Uniòns of Aragon and Valencia, as well as his conflict with Pedro I of Castile. …

When Does The Straw Break The Camel's Back?: Examination Of The Exclusion-Elicited Anti-Social Behavior Model, Douglas Phillip Cooper

USF Tampa Graduate Theses and Dissertations

Being excluded should motivate pro-social behaviors. Yet, exclusion can incite aggressive and anti-social responses. Two studies were conducted to examine how frequent experiences of exclusion impact self-esteem, perceptions that exclusion is typical of social experiences, and anti-social behaviors. In Study 1, participants completed pre and post-measures of exclusion typicality and self-esteem and reported, over eight weeks, feelings of exclusion and state self-esteem. Results supported the hypotheses in that experiences feeling excluded have direct and indirect effects on state and trait self-esteem as well as on exclusion typicality. In Study 2, participants were exposed to an exclusion manipulation and subsequent aggressive …

Lead Discovery And Optimization Strategies Towards The Development Of 4(1h)-Quinolones And 1,2,3,4-Tetrahydroacridone Analogs With Antimalarial Activity, Richard Matthew Cross

USF Tampa Graduate Theses and Dissertations

The goal of our research endeavor was to successfully employ modern lead discovery and optimization strategies towards the development and identification of compounds possessing antimalarial activity. Preliminary data from in vitro screening at the Walter Reed Army Institute of Research identified several chemotypes including 4(1H)-quinolones and 1,2,3,4-tetrahydroacridones to have potent antimalarial activities. Multiple synthetic routes were devised and implemented which enabled the rapid preparation and isolation of over 400 structurally diverse 4(1H)-quinolones and 1,2,3,4-tetrahydroacridones.

Our research towards discovering and optimizing antimalarials was inspired from the severe impact malaria has had on our planet especially on impoverished countries. There are over …

Guanidines, Amidines And Carbamides As Novel Sigma Receptor Ligands For Post-Stroke Therapeutics, Michelle Yolanda Cortes-Salva

USF Tampa Graduate Theses and Dissertations

Stroke is the 3^rd leading cause of death in the United States. For this reason, it has become our goal to find a drug that is capable of reestablishing intracellular and extracellular Ca⁺² flux upon direct binding to the sigma receptor, which can be delivered easily and efficiently. Our active research focuses the development of guanidine analogues that can serve as therapeutic drugs which target sigma 1 and sigma 2 receptors having a direct effect on Ca⁺² levels on the cell. The use of symmetrical guanidine analogues such as N,N'-di-o-tolyl guanidine (o-DTG) as therapeutic drugs for ischemic …

Mechanistic Modeling Of Photocatalytic Water Disinfection, Omatoyo Kofi Dalrymple

USF Tampa Graduate Theses and Dissertations

The main goal of this research was to develop a mechanism-based model for photocatalytic disinfection of bacteria in water using suspended catalyst pthesiss in batch reactors. The photocatalytic disinfection process occurs as a semiconductor photocatalyst, most commonly titanium dioxide (TiO₂), is irradiated with light of wavelength less than 380 nm to produce hydroxyl radicals and other highly reactive oxidants which can inactivate microorganisms. Photocatalytic disinfection involves a complex interaction of many fundamental mechanisms such as light absorption and scattering by semiconductor pthesiss, electrochemical surface reactions, and heterogeneous colloidal stability. Current models, based largely on chemical reacting systems, do …

"A Blaze Of Light And Finery": The Victorian Theater And The Victorian Theatrical Novel, Dorinda Mari Davis

USF Tampa Graduate Theses and Dissertations

The concept of the Victorian antitheatrical prejudice is both well-established and well-respected. This paper, however, examining the Victorian theatrical novel and the Victorian theater in terms of that prejudice, finds the ready assumption of the prejudice to be problematic at best. A close look at three novels that together span the early to mid-nineteenth century shows that, far from being ubiquitous and unilateral, antitheatricality was in many cases an anomaly; indeed, many of those novelistic elements that have long been assumed to be antitheatrical address different issues altogether. Employing close readings of the novels--Jane Austen's Mansfield Park, Charles Dickens's …

"Can't Buy Me Wealth": Racial Segregation And Housing Wealth In Hillsborough County, Florida, Natalie Marie Delia Deckard

USF Tampa Graduate Theses and Dissertations

Informed by the literature regarding the gap in wealth between white and non-white households in the United States, as well as the literature on segregation and neighborhood preference, this research explores the home value component of the wealth gap in Hillsborough County, Florida. It finds that homes in Predominantly Black or Hispanic neighborhoods are not only undervalued compared to Predominantly White and heterogeneous neighborhoods, but have appreciated more slowly at least since 2000. The research also finds that buyers identifying as black or Hispanic are more likely than those identifying as white or "other" to purchase homes in Predominantly Black …

Role Of Protein Kinase C-Iota In Glioblastoma, Shraddha R. Desai

USF Tampa Graduate Theses and Dissertations

The focus of this research was to investigate the role of protein kinase C-iota (PKC-é) in the regulation of Bad function, a pro-apoptotic member of the Bcl-2 family and Cdk7 function, a master cell cycle regulator in glioblastoma.

The results were obtained from the human glial tumor derived cell lines, T98G and U87MG. In these cells, PKC-é co-localized and directly associated with Bad as shown by immunofluorescence, immunoprecipitation, and Western blotting. Furthermore, in-vitro kinase activity assay showed that PKC-é directly phosphorylated Bad at phospho specific residues, S112, S136 and S155 which in turn induced inactivation of Bad and disruption of …

Population Genetics Of Amphiuma Means And Siren Lacertina In Central Florida, Anna C. Deyle

USF Tampa Graduate Theses and Dissertations

Population structure can be defined as a difference in the frequencies of alleles among populations, and it is often caused by barriers to dispersal. I used mitochondrial DNA sequences to examine the population structure of two large, aquatic salamanders, Amphiuma means (the Two-Toed Amphiuma) and Siren lacertina (the Greater Siren), at two spatial scales in peninsular Florida. Both species appear to have similar life histories, including poor dry land dispersal capabilities, and I hypothesized that they would exhibit significant population structure at both broad and fine scales. Wetland loss and landscape fragmentation are certain to have caused decreases in abundance …

Philosophical Precursors To The Radical Enlightenment: Vignettes On The Struggle Between Philosophy And Theology From The Greeks To Leibniz With Special Emphasis On Spinoza, Anthony John Desantis

USF Tampa Graduate Theses and Dissertations

My dissertation lays out some of the chief philosophical precursors to Jonathan Israel's Radical Enlightenment. It investigates the principal question of Will Durant's The Age of Voltaire: "How did it come about that a major part of the educated classes in Europe and America has lost faith in the theology that for fifteen centuries gave supernatural sanctions and supports to the precarious and uncongenial moral code upon which Western civilization has been based?" The aim of this project is both broad and specific: the first is to provide a general history of the philosophical precursors to the Radical Enlightenment up …

Theoretical And Experimental Analysis Of Power And Cooling Cogeneration Utilizing Low Temperature Heat Sources, Gökmen Demirkaya

USF Tampa Graduate Theses and Dissertations

Development of innovative thermodynamic cycles is important for the efficient utilization of low-temperature heat sources such as solar, geothermal, and waste heat sources. Binary mixtures exhibit variable boiling temperatures during the boiling process, which leads to a good thermal match between the heating fluid and working fluid for efficient heat source utilization. This study presents a theoretical and an experimental analysis of a combined power/cooling cycle, which combines the Rankine and absorption refrigeration cycles, uses ammonia-water mixture as the working fluid and produces power and refrigeration, while power is the primary goal. This cycle, also known as the Goswami Cycle, …

The Integration Of African Muslim Minority: A Critique Of French Philosophy And Policy, Amber Nichole Dillender

USF Tampa Graduate Theses and Dissertations

The numerous images of violence perpetrated by radicalized followers of Islam, has highlighted the complexities surrounding assimilation and integration of Muslims in Western society. Since the guest worker recruitment from French African colonies initiated after World War II, France has been witness to the unanticipated development of permanent communities of African laborers, many of whom are Muslim. Despite consistent promotion of French monoculture and specifically the use of the assimilation model for integration, segregation of African Muslims has occurred. Through the construction of a single country case study, I explore integration issues surrounding the French Muslim minority communities. I seek …

A National Survey Of Instructional Strategies Used To Teach Information Systems Courses: An Exploratory Investigation, Yenni Merlin Djajalaksana

USF Tampa Graduate Theses and Dissertations

Many universities and colleges have placed increased emphasis on teaching excellence in higher education. Efforts to promote teaching excellence vary from the development of alternative new pedagogies as well as research exploring strategies to improve existing teaching practices. Logically, different disciplines employ different instructional strategies to prepare their graduates with specific skills, knowledge, and attitudes. This study examined the instructional strategies used most frequently in the information systems discipline and was inspired by Shulman's (2005) concept of signature pedagogies - the unique but pervasive ways of teaching within a discipline or profession.

This dissertation reports a national survey of instructional …

Steady And Transient Heat Transfer For Jet Impingement On Patterned Surfaces, Mark Michael Dobbertean

USF Tampa Graduate Theses and Dissertations

Free liquid-jet impingement is well researched due to its high heat transfer ability and ease of implementation. This study considers both the steady state and transient heating of a patterned plate under slot-free-liquid jet impingement. The primary working fluid was water (H2O) and the plate material considered was silicon. Calculations were done for Reynolds number (Re) ranging from 500 to 1000 and indentation depths from 0.000125 to 0.0005 m for three different surface configurations. The effect of using different plate materials and R-134a as the working fluid were explored for the rectangular step case. The distributions of the local and …

Population Biology, Ecology, And Ecosystem Contributions Of The Eastern Oyster (Crassostrea Virginica) From Natural And Artificial Habitats In Tampa Bay, Florida, Michael Drexler

USF Tampa Graduate Theses and Dissertations

The objective of this project was to document the status of oysters, Crassostrea virginica, from non-reef habitats throughout Tampa Bay, Florida, and assess the ecosystem contributions of those populations relative to reef-dwelling oysters. The aspects of oyster ecology studied here include condition, prevalence and intensity of disease (Perkinsus marinus - dermo), reproductive activity (including stage, fecundity, and juvenile recruitment), adult oyster density, and the faunal community associated with the oysters.

The predominant source of variation was seasonal, with lesser contributions among sites, and in most cases, little or no effect of the habitat type. Oysters populations from each habitat …

Up In The Air: The Global Economy, Economic Development, And Air Transportation In Tampa Bay, Florida, Clinton M. Elbow

USF Tampa Graduate Theses and Dissertations

A globally integrated economy is one of the most prominent features of globalization and how city stakeholders respond to the global economy varies from city to city. Connecting to the global economy is often portrayed to be necessary for the continued economic development of a metropolitan area. Large transportation infrastructures such as airports represent one of the most visible ways of connecting to the global economy. Decisions made by city stakeholders regarding airports in order to reposition their city in the global economy have profound consequences for its residents. This thesis aims to examine the role played by air transportation …

Shifting Blackness: How The Arts Revolutionize Black Identity In The Postmodern West, Reginald Eldridge Jr

USF Tampa Graduate Theses and Dissertations

The contemporary experiences of racially marginalized people in the West are affected deeply by the hegemonic capitalist Orthodox cultural codes, or episteme, in which blackness operates as the symbol of Chaos. As it relates to people of African descent, these affects are marked by a denial of the black person's full status as an unproblematic subject, by ontological voids arising from the practice of enslavement over the past centuries, and by problems of representation within the West, where examples and points of reference for black identity are always tied up with conflicting interests.

Utilizing Sylvia Wynter's model of the Ceremony …

Regulation Of Cell Adhesion Strength By Spatial Organization Of Focal Adhesions, Kranthi Kumar Elineni

USF Tampa Graduate Theses and Dissertations

Cell adhesion to extracellular matrix (ECM) is critical to various cellular processes like cell spreading, migration, growth and apoptosis. At the tissue level, cell adhesion is important in the pathological and physiological processes that regulate the tissue morphogenesis. Cell adhesion to the ECM is primarily mediated by the integrin family of receptors. The receptors that are recruited to the surface are reinforced by structural and signaling proteins at the adhesive sites forming focal adhesions that connect the cytoskeleton to further stabilize the adhesions. The functional roles of these focal adhesions extend beyond stabilizing adhesions and transduce mechanical signals at the …

Multivariate Anti-Inflammatory Approaches To Rescue Neurogenesis And Cognitive Function In Aged Animals, Sandra Antonieta Acosta

USF Tampa Graduate Theses and Dissertations

Studies have shown that there is a strong correlation between aging and neurodegenerative diseases. Aging is considered the number one risk factor to develop neuropathologies such as memory loss, senile dementia, Alzheimer's disease (AD), and Parkinson's disease. Neurodegenerative diseases tend to start during adulthood, and aggravate over time, making them difficult to prevent and to treat. In the Unites States, demographic studies by U.S. Bureau of the Census have determined that our aging population of >65 years is expected to increase from the present 35 million to 78 million in 2030. This would result, not only to an increase of …