Experimental Analysis of Behavior Commons^™

Association Of Anxiety And Executive Function With Attendance And Fitness Improvement In Cardiac Rehabilitation, William A. Middleton

Graduate College Dissertations and Theses

Psychological factors such as anxiety and executive function (EF) may impact patient health outcomes from cardiac rehabilitation (CR). High anxiety and low executive function could reduce attendance or impede fitness improvements yielded from CR. Other research on exercise performance suggests, in certain circumstances, moderate levels of anxiety can be beneficial towards fitness gains. The current study evaluated the associations of anxiety and EF with attendance and fitness improvement in CR through retrospective analyses of two datasets from studies conducted at the University of Vermont Medical Center CR program. One sample contained a representative sample of CR patients, and the other, …

Examining Antepartum Quit Attempts Using A Latent Factor Model Of A Hypothetical Cigarette Purchase Task, Carolyn Grace Evemy

Graduate College Dissertations and Theses

Previous research has validated the use of hypothetical purchase tasks to measure smoking demand among pregnant women. This study extends that research by (1) examining the factor loading pattern of a hypothetical cigarette purchase task (CPT) in a sample of pregnant women who smoke, and (2) comparing the ability of the latent factor solution to predict antepartum quit attempts relative to more conventional predictors. Participants were 665 pregnant women seeking enrollment in a smartphone-based smoking-cessation trial. Data were taken from an intake assessment that included the CPT, the Kirby delayed discounting task, sociodemographic and smoking-history questionnaires, and assessment of antepartum …

Examining Sucrose Subjective Response Among Individuals With Opioid Use Disorder, Taylor Anne Ochalek

Graduate College Dissertations and Theses

Aims: Opioid use disorder (OUD) is associated with significant morbidity and mortality, and opioid agonist treatment (OAT) with methadone or buprenorphine represents the most efficacious treatment. However, data suggest that chronic administration of opioids may be associated with significant weight gain, possibly by altering an organism’s perception of and preference for sweet foods. The primary aim of this laboratory study was to rigorously examine sucrose subjective response among adults receiving OAT and a comparison sample without OUD. As secondary outcomes, we also sought to compare the groups on additional baseline characteristics that may influence subjective sucrose response and weight gain …

Cost-Effectiveness Analysis Of Two Contraceptive Services Interventions For Women Receiving Medication For Opioid Use Disorder And At Risk Of Unintended Pregnancy, Heidi S. Melbostad

Graduate College Dissertations and Theses

Background: In the BCII randomized clinical trial, women receiving medication for opioid use disorder (OUD) and at risk of unintended pregnancy who received contraceptive services interventions co-located with an OUD treatment facility had significantly higher rates of prescription contraceptive use than those who received usual care. To support informed decision-making about using these interventions in community-based settings, I conducted a cost-effectiveness analysis to determine the costs and health benefits associated with these interventions.

Methods: I used the standard practice of calculating incremental cost effectiveness ratios (ICERs) between the trial conditions (i.e., usual care, contraceptive services, and contraceptive services + incentives) …

Examining The Malleability Of Cigarette Product Preference, Danielle Rose Davis

Graduate College Dissertations and Theses

Introduction: Cigarette preference increases as a function of nicotine content, but preference can be shifted by manipulating cigarette cost. The aim of the present study is to model whether the behavioral-economic metric of unit price (cigarette cost/nicotine content) accounts for cigarette preference shifts and whether preference changes to very low nicotine content cigarettes (VLNCs) are associated with corresponding changes in smoking rate.

Methods: 169 daily smokers from populations vulnerable to smoking completed sessions in which choices between smoking normal nicotine content (NNC) (15.8mg/g) and VLNC (0.4mg/g) cigarettes were concurrently available. In Condition 1, choices for both products were available ad-lib …

Biobehavioral Predictors Of Cannabis Use In Adolescence, Philip Aaron Spechler

Graduate College Dissertations and Theses

Cannabis use initiated during adolescence may precipitate lasting consequences on the brain and behavioral health of the individual. However, research on the risk factors for cannabis use during adolescence has been largely cross-sectional in design. Despite the few prospective studies, even less is known about the neurobiological predictors. This dissertation improves on the extant literature by leveraging a large longitudinal study to uncover the predictors of cannabis use in adolescent samples collected prior to exposure. All data were drawn from the IMAGEN study and contained a large sample of adolescents studied at age 14 (N=2,224), and followed up at age …

A Social Identity Threat To Merit: The Effects Of Similar Experience On Empathic Concern, Asia Mccleary-Gaddy

Graduate College Dissertations and Theses

Past research indicates that having a similar life experience as another person leads to greater empathic concern towards that person. Two studies empirically investigated if similar experiences of race-based social identity threat can increase the empathic concern of White Americans toward African Americans. Study 1 revealed that White Americans randomly assigned to think about White privilege and then randomly assigned to read a passage about an African American whose accomplishments are attributed to Affirmative Action policies (versus an African American whose accomplishments are attributed to his hard work and merit) felt greater empathic concern toward the African American described in …

Examining The Roles Of Sex, Methamphetamine, And Degree Of Training In Habit Formation In Rats, Hannah Schoenberg

Graduate College Dissertations and Theses

Addiction is characterized by a progressive loss of executive control over drug-seeking and consumption, and may be associated with a behavioral shift from instrumental goal-directed actions to stimulus-response habits. Sex differences in drug addiction have been linked to changing hormone levels across the estrous cycle, and females exhibit a particular vulnerability to psychostimulants such as cocaine and amphetamines. Psychostimulants and estrogen both influence dopaminergic activity in the dorsal striatum, a region of the brain in which dopamine activity is thought to mediate the shift from action to habit. In the present set of experiments, we examined the roles of sex, …

A Novel Mhealth Application For Improving Hiv And Hepatitis C Knowledge In Individuals With Opioid Use Disorder, Taylor A. Ochalek

Graduate College Dissertations and Theses

Aims: Untreated opioid use disorder (OUD) is associated with overdose, premature death and infectious disease, including human immunodeficiency virus (HIV) and Hepatitis C (HCV). While prior studies have shown that educational interventions are associated with improvements in HIV and HCV knowledge and reductions in risk behaviors, those examined to date have typically been time- and resource-intensive. We recently developed an HIV+HCV Education intervention which aims to improve HIV and HCV knowledge in a single visit using an automated iPad platform. In this project, we examined its ability, using a within-subject evaluation, to improve knowledge of HIV and HCV transmission and …

Renewal In The Context Of Stress: A Potential Mechanism Of Stress-Induced Reinstatement, Scott Timothy Schepers

Graduate College Dissertations and Theses

In the animal laboratory, stressors can produce the relapse of drug-seeking behaviors after the behavior has been inhibited by extinction. This type of relapse has been called stress-induced reinstatement, and it models the relapse that is commonly reported in human populations. Interestingly, in the laboratory, stress does not typically reinstate extinguished behaviors that have been reinforced by food. One account of the discrepancy is that drugs of abuse may induce stress; therefore, when organisms learn to respond for drugs, they might learn to make the response in the “context” of stress. If so, then stress-induced reinstatement may be better described …

Cues Associated With Alternative Reinforcement Can Attenuate Resurgence Of An Extinguished Instrumental Response, Sydney Trask

Graduate College Dissertations and Theses

In resurgence, a target behavior (R1) is acquired in an initial phase and extinguished in a second phase while an alternative behavior (R2) is reinforced. When reinforcement for the second response is removed, however, R1 behavior returns or “resurges.” The resurgence paradigm may have implications for understanding relapse after behavioral interventions in humans such as contingency management, or CM, in which (for example) drug users can earn vouchers contingent upon drug abstinence. The present experiments examined the effectiveness of a putative retrieval cue for treatment in attenuating the resurgence effects and determined the likely mechanism by which this cue functions. …

Comparing The Effects Of Menthol Status On The Behavioral Pharmacology Of Smoking Reduced Nicotine Content Cigarettes, Danielle Davis

Graduate College Dissertations and Theses

Introduction: An active area of tobacco regulatory science research focuses on examining the effects of varying the nicotine content of cigarettes as part of a potential national policy to lower their nicotine content levels to reduce addiction potential. The present study examines differences in the behavioral effects of reduced nicotine content cigarettes related to their menthol status. Menthol is the only cigarette flavoring that is still legally permissible according to Food and Drug administration regulations.

Methods: Participants were 26 current adult smokers from three populations especially vulnerable to tobacco use and addiction (economically disadvantaged women, opioid-dependent individuals, individuals with affective …

The Effects Of Self-Threats And Affirmations On Romantic Relationship Functioning: The Moderating Roles Of Self-Esteem And Relationship-Contingent Self-Esteem, Jennifer Lynn Zangl

Graduate College Dissertations and Theses

Although romantic relationships are an important source of self-esteem, individuals vary in the degree to which romantic relationships determine their self-esteem. For individuals with relationship-contingent self-esteem (RCSE), self-esteem is based on the quality of perceived romantic relationship functioning. In contrast, global self-esteem is derived from a variety of domains, not specifically relationship quality. The present study investigated the moderating effects of RCSE and global self-esteem on the effects of relationship specific or relationship-unrelated threats and self-affirmations. Individuals with low global self-esteem react to threats by distancing themselves from their romantic partners. For those low in RCSE, this should occur only …

Learning Related Regulation Of A Voltage-Gated Ion Channel In The Cerebellum, Jason R. Fuchs

Graduate College Dissertations and Theses

The neural mechanisms that support learning and memory are still poorly understood. Much work has focused on changes in neurotransmitter receptor expression, while changes in voltage-gated ion channel expression have been largely unexplored, despite the fact that voltage-gated ion channels govern neuronal excitability. Here we used eyeblink conditioning (EBC) in rats, a model of learning and memory with a well-understood neural circuit, to examine regulation of voltage-gated ion channels as a consequence of learning. EBC is a form of classical conditioning that involves pairings of a behaviorally neutral conditioned stimulus (CS) and an eyeblink eliciting unconditioned stimulus (US) over many …

Understanding Everyday Decisions: An Examination Of Biases In Decision-Making, Educational Attainment, And Use Of Tobacco And Nicotine Delivery Products Among Women Of Reproductive Age, Laura L. Chivers

Graduate College Dissertations and Theses

The aim of this study was to examine associations between biases in decision-making (delay discounting [DD], opportunity cost neglect [OCN], status quo bias [SQB]), educational attainment, and use of cigarettes and other tobacco and nicotine delivery products among women of reproductive age. Women of reproductive age are of special interest because of the additional risks that cigarette smoking or use of these other products represents should they become pregnant. Data were collected anonymously online in survey format using Amazon Mechanical Turk [AMT]. Participants were 800 women of reproductive age (24-44 years) from across the US. Half (n = 400) were …