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Full-Text Articles in Clinical Psychology

Gender Differences In Relations Between Social Comparison, Social Support, And Sleep Disturbance Among Midlife And Older Adults., Iris Bercovitz, Gabrielle M Salvatore, Jacqueline A Mogle, Danielle Arigo Aug 2024

Gender Differences In Relations Between Social Comparison, Social Support, And Sleep Disturbance Among Midlife And Older Adults., Iris Bercovitz, Gabrielle M Salvatore, Jacqueline A Mogle, Danielle Arigo

College of Science & Mathematics Departmental Research

OBJECTIVE: To examine associations between sleep disturbance, social support, and social comparison among midlife and older adults, including the moderating role of gender.

METHODS: Adults ages ≥40 years (N = 557, MAge = 57, 53% men) completed a cross-sectional survey including validated measures of sleep disturbance, perceptions of social support, and social comparison orientation.

RESULTS: Sleep disturbance was negatively associated with social support (rs = −0.42 to–0.33, ps = 0.001) and associations were stronger for men than women–particularly perceived support from friends (η 2= 0.01). Sleep disturbance was also associated with upward comparison orientation (r = 0.12, p = 0.003), …


The Relationship Between Amygdala And Orbitofrontal Cortex Volume In The Context Of Oppositional Defiant Disorder, Rahul Alla May 2024

The Relationship Between Amygdala And Orbitofrontal Cortex Volume In The Context Of Oppositional Defiant Disorder, Rahul Alla

Honors Scholar Theses

Disobedient and rebellious attitude in children is on the rise and this type of behavior is categorized as Oppositional Defiant Disorder (ODD). ODD in children can be identified as a persistent pattern of angry or irritable mood, argumentative or defiant behavior or vindictiveness toward others according to the Diagnostic and Statistical Manual (DSM-5, Fifth Edition) of Mental Disorders.1 Children with ODD typically have difficulty regulating and processing their emotions. Issues with regulating emotions is defined as the process by which individuals “influence which emotions they have, when they have them, and how they experience and express them”.2 Dysregulation of emotions …


Denial Of Pregnancy Or Cryptic Pregnancy, Nadia N. Shuriah, Elaine Mcfarland, Bethany Spenn, Kaisha Butz Mcmanus Apr 2024

Denial Of Pregnancy Or Cryptic Pregnancy, Nadia N. Shuriah, Elaine Mcfarland, Bethany Spenn, Kaisha Butz Mcmanus

BIO4960: Practicum in Biology I

Denial of pregnancy, or cryptic pregnancy, presents a complex situation where individuals are unaware of their pregnancy until the late stages of labor. This study delves into the multifaceted nature of concealed and denied pregnancies, exploring their prevalence, factors contributing to them, and their implications for both individuals and healthcare systems. By reviewing relevant literature and case studies, we aim to illuminate the difficulties healthcare providers face in identifying and managing cases of denial of pregnancy. Additionally, we stress the significance of proactive screening and comprehensive care to ensure the well-being of mothers and infants. This research endeavors to deepen …


The Relationship Between Cognitive Impairment In Psychiatric Patients And Readmission Rate To An Inpatient Facility, Cherilyn Isis Schuff Feb 2024

The Relationship Between Cognitive Impairment In Psychiatric Patients And Readmission Rate To An Inpatient Facility, Cherilyn Isis Schuff

Theses and Dissertations

The primary intention of this study was to further understand the impact of assessing cognitive impairment in psychiatric patients, as a mediating factor on readmission rates. Mild cognitive dysfunction impacts a patient’s functional outcomes (Bowie & Harvey, 2006; Davis et al., 2012; Marcantonio, et al., 2001). Little information exists to guide best practices in the treatment of adults with cognitive impairment who are hospitalized for acute conditions (Davis et al., 2012). A cognitive impairment may impact patient prognosis and ability to function outside of a setting focused on stabilization. Neuropsychological testing is a valuable tool in predicting a patient’s cognitive …


Characterizing Resting Cerebral Blood Flow In Obsessive-Compulsive Disorder With Arterial Spin Labeling, Hannah R. Wild Jan 2024

Characterizing Resting Cerebral Blood Flow In Obsessive-Compulsive Disorder With Arterial Spin Labeling, Hannah R. Wild

Theses and Dissertations--Psychology

Obsessive-compulsive disorder (OCD) is a condition characterized by intrusive thoughts (obsessions) and ritualistic behaviors (compulsions) profoundly impacting daily functioning and quality of life. Neuroimaging studies using various techniques have revealed inconsistent resting cerebral blood flow (rCBF) patterns in OCD patients, particularly within the cortico-striatal-thalamo-cortical (CSTC) circuit and sensorimotor network. Arterial Spin Labeling (ASL) MRI offers a promising, noninvasive method for directly measuring rCBF. This study, using data from the Yale HCP Trio study, analyzed unmedicated OCD patients and healthy controls, who underwent two consecutive resting pulsed-ASL scans. OCD patients with lower obsessional severity exhibited higher perfusion in the pre- and …


Cerebrospinal Fluid Biomarkers Not Associated With Neurologic Compromise Among Mild Cognitively Impaired Reverters With Parkinson's Disease, Cameron Ryczek Dec 2023

Cerebrospinal Fluid Biomarkers Not Associated With Neurologic Compromise Among Mild Cognitively Impaired Reverters With Parkinson's Disease, Cameron Ryczek

Electronic Theses, Projects, and Dissertations

Parkinson's Disease (PD) is a neurodegenerative disease characterized by motor (e.g. tremors) and non-motor symptoms (e.g. cognitive impairment). PD patients' change in cognitive functioning can be observed using the following classifications: cognitively intact, mild cognitive impairment (MCI), or dementia (PDD). MCI has many subtypes, one of which is MCI reversion which is defined as those with MCI at one time point reverting to cognitively intact later. While there is limited research into the utility of MCI reversion and its relationship with cerebrospinal fluid (CSF) biomarkers in PD, this study will begin to elucidate this relationship. To this end, data from …


Affect, Mind-Body Factors, And Disordered And Intuitive Eating Behaviors: Examining Naturalistic Associations Among Young Women With Elevated Eating Disorder Symptoms, Kelly A. Romano Aug 2023

Affect, Mind-Body Factors, And Disordered And Intuitive Eating Behaviors: Examining Naturalistic Associations Among Young Women With Elevated Eating Disorder Symptoms, Kelly A. Romano

Psychology Theses & Dissertations

Objective: The present study examined whether three mind-body factors—emotion dysregulation, interoceptive sensibility, and mindfulness—that are theorized to be implicated in the onset and maintenance of eating disorder (ED) pathology mediated (Aim 1) and moderated (Aim 2) within-person associations between affect and women with elevated ED symptoms’ disordered and intuitive eating behavior use. Method: Participants included 150 young women with elevated ED symptoms who completed a 10-day ecological momentary assessment protocol. To address Aim 1, multilevel structural equation models examined whether the mindbody factors (separately) mediated momentary associations between negative and positive affect, and women’s disordered (dietary restriction, loss of control …


Peer-Supervision Of Nursing Professionals: A Shield Against Burnout, Kyle Gamache, Sarah Gamache, Joseph Robillard Apr 2023

Peer-Supervision Of Nursing Professionals: A Shield Against Burnout, Kyle Gamache, Sarah Gamache, Joseph Robillard

Journal of Wellness

Introduction: Burnout is a major risk in healthcare professions and is a significant contributor to the current nursing shortage. Strategies to combat burnout of healthcare professionals are in desperate need. The purpose of this project is to introduce the clinical peer supervision model as a method to alleviate burnout in nursing professionals.

Approach: Eight nurses from in-patient settings participated in a peer-supervision support group, modeled after existing European nursing and mental health provider-support protocols. To assess the effect of this intervention, qualitative data analysis was conducted on the transcripts of session and the results described. All participants reported statistically high …


Executive Functioning Among The Karyotypes In Turner Syndrome And Implications For Interventions, Sara Scull Jan 2023

Executive Functioning Among The Karyotypes In Turner Syndrome And Implications For Interventions, Sara Scull

Antioch University Dissertations & Theses

Turner syndrome (TS) is a genetic disorder seen in phenotypically female (pf) individuals who have either a complete or partial absence of the second sex (X) chromosome. TS includes different karyotypes, and it presents with a variety of phenotypic and genotypic features. In general, the neuropsychological profiles for individuals diagnosed suggest that TS can contribute to challenges in various aspects of daily life, including social and emotional functioning. With regard to academic performances, individuals with TS often present with relative strengths in a range of verbal abilities and relative weakness in visual-spatial/perceptual abilities, nonverbal memory, motor function, processing speed, executive …


Complex Narratives Of Individuals Living With Alpha-Gal Syndrome (Ags). A Mixed-Methods Investigation: Examined Through Self-Reported Data, In-Person Interviews, And A Group Body Mapping Art Therapy Intervention, Sylvan Streightiff Jan 2023

Complex Narratives Of Individuals Living With Alpha-Gal Syndrome (Ags). A Mixed-Methods Investigation: Examined Through Self-Reported Data, In-Person Interviews, And A Group Body Mapping Art Therapy Intervention, Sylvan Streightiff

Art Therapy | Master's Theses

Alpha-gal (galactose-α-1,3-galactose) Syndrome or AGS is an under-recognized chronic condition which coincides with tick-bite exposure, resulting in a unique allergy to non-primate mammalian products and byproducts (in addition to other items caring the α-gal epitope such as carrageenan, agar-agar, and nori). This paper explores the experiences of individuals with this illness, establishing psychological context for expressed symptomatology, while emphasizing the complex trauma rooted in the population’s experiences of the life-altering and life-threatening contexts associated with managing AGS. This research is structured with Acceptance and Commitment Therapy (ACT) theory and utilizes a mixed-methods approach to arts-based research with the goal of …


Examining Genetically-Informed Etiologic Models Of Co-Occurring Posttraumatic Stress Disorder And Recreational Cannabis Use Among College Students, Terrell A. Hicks Jan 2023

Examining Genetically-Informed Etiologic Models Of Co-Occurring Posttraumatic Stress Disorder And Recreational Cannabis Use Among College Students, Terrell A. Hicks

Theses and Dissertations

The college years encompass a period of increased risk recreational cannabis use (RCU), as well as a time of increased risk for trauma exposure and developing posttraumatic stress disorder (PTSD). Given the high co-occurrence between RCU and PTSD, and the potentially negative consequences of the two (e.g., worse academic outcomes), there is a need to understand the etiologic mechanisms of these commonly co-occurring conditions. Two primary phenotypic models exist: self-medication model (i.e., PTSD to RCU) and the high-risk model (i.e., RCU to PTSD). To date, there are two existing studies longitudinally examining the etiologic models proposed to explain co-occurring RCU …


Psychophysiological Effects Of Increasing Awareness Of Nondual Consciousness In Young Adults With Depression And Anxiety, Milena Braticevic Oct 2022

Psychophysiological Effects Of Increasing Awareness Of Nondual Consciousness In Young Adults With Depression And Anxiety, Milena Braticevic

CONSCIOUSNESS: Ideas and Research for the Twenty-First Century

Young adults increasingly suffer from anxiety and depression during the time of transition into adulthood. This research study examined the effects of increasing awareness of nondual consciousness in young adults who were experiencing various levels of anxiety and depression. The methodology was mixed-method and included four 1-hour group-based sessions over 4 weeks. Increasing awareness of nondual consciousness through educational, experiential, and behavioural components resulted in reduction in the average depression score from 19.4 (borderline clinical depression) to 10 (normal), and reduction in the average anxiety score from 12.7 (moderate anxiety) to 6.9 (mild). Participants reported increased mental, emotional, physical, and …


Cognitive Testing For Sport Concussion: The Immediate Post-Concussion Assessment And Cognitive Testing (Impact), Julia E. Maietta Aug 2022

Cognitive Testing For Sport Concussion: The Immediate Post-Concussion Assessment And Cognitive Testing (Impact), Julia E. Maietta

UNLV Theses, Dissertations, Professional Papers, and Capstones

Sport concussion is among the most common injuries for an athlete to experience during sport participation. Because of the complex pathophysiological process that affects the brain during and after concussion, symptoms can be heterogeneous in presence and severity. Although most acute symptoms (e.g., headache, slowed processing speed, loss of consciousness, irritability, depression, anxiety) resolve within seven to 10 days for most athletes, there is evidence that higher initial symptom burden and other genetically based differences can lead to longer symptom duration and complicated recovery post-concussion. Because structural changes that commonly occur as a result of concussion (e.g., diffuse axonal injury) …


Temporal Dynamics Of Attention Bias In Anxiety: An Eye Tracking Study, Abel Mathew Aug 2022

Temporal Dynamics Of Attention Bias In Anxiety: An Eye Tracking Study, Abel Mathew

Theses and Dissertations

Behavioral reaction time (RT) measures, like the dot-probe and spatial cueing tasks, have shown that individuals with anxiety tend to bias their attention toward threat as compared to neutral stimuli. However, the literature has revealed mixed findings due to the simplistic calculation of attention bias (AB; i.e., Mean RT Threat – Mean RT Neutral). Research has shown that attention bias fluctuation (i.e., patterns of both vigilance and avoidance), is indicative of attention dyscontrol, which is evident in those with psychopathology. As such, the purpose of this study was to evaluate whether AB fluctuation via behavioral RT measures and eye-tracking, stands …


Evaluating The Impact Of A Safe Exercise Training Workshop On Knowledge And Self-Efficacy To Manage Dysfunctional Exercise Among Eating Disorders Clinicians At Alsana Eating Disorders Center, Danika A. Quesnel Jun 2022

Evaluating The Impact Of A Safe Exercise Training Workshop On Knowledge And Self-Efficacy To Manage Dysfunctional Exercise Among Eating Disorders Clinicians At Alsana Eating Disorders Center, Danika A. Quesnel

Electronic Thesis and Dissertation Repository

Engaging in dysfunctional exercise (DEX) is detrimental to eating disorders (EDs) prognosis, although common amongst clients. Though nutritionally supported exercise can improve ED treatment outcomes, without negatively impacting weight restoration, clinicians remain hesitant to address DEX, perhaps due to a lack of information and training. The current study examined the effects of a Safe Exercise at Every Stage (SEES) training on clinician knowledge and self-efficacy in managing DEX in ED treatment. Eating disorders clinicians completed measures before (n = 96) and after (n = 44) SEES training to assess their knowledge and self-efficacy around treating DEX, with a …


The Relationship Between Perceived Stress And Disordered Eating In Undergraduate Students During The Covid-19 Pandemic, Caroline G. Martin May 2022

The Relationship Between Perceived Stress And Disordered Eating In Undergraduate Students During The Covid-19 Pandemic, Caroline G. Martin

Gettysburg College Headquarters

The COVID-19 pandemic has affected and imposed challenges on nearly everyone, including college students. Despite their already stressful situations, previous research has demonstrated increased stress levels among college students during the COVID-19 pandemic. Additionally, research has also shown an increase in disordered eating for college students during the pandemic. However, few studies have investigated the relationship between both perceived stress and disordered eating during the COVID-19 pandemic. Therefore, the present study used a correlational design to investigate a potential association between perceived stress and disordered eating among undergraduate college students during the COVID-19 pandemic. By administering the EAT-26, the CSSEC, …


Trauma Healing With The Neurosequential Model Of Therapy And Bal-A-Vis-X, Becky Johnston May 2022

Trauma Healing With The Neurosequential Model Of Therapy And Bal-A-Vis-X, Becky Johnston

Educational Specialist, 2020-current

Stigma related to childhood trauma is shifting with the help of advancements in the understanding of neurobiology and interventions that are proving to be effective for healing. There are immense costs and consequences for survivors of childhood trauma and their loved ones that were not so long ago considered irrelevant and the notion that kids bounce back from adversity was previously popular in the psychological community (Perry & Szalavitz, 2017). The broad strokes of Dr. Bruce Perry’s clinical intervention model, The Neurosequential Model of Therapy (NMT) describes a trauma-sensitive, sequential approach to changing the stress response within mental health counseling. …


Effects Of Music Exposure On Autobiographical Memory In Alzheimer's Patients: A Systematic Review And Meta-Analysis, Gregory Vance May 2022

Effects Of Music Exposure On Autobiographical Memory In Alzheimer's Patients: A Systematic Review And Meta-Analysis, Gregory Vance

Honors Theses

The progression of Alzheimer’s disease is primarily characterized by a loss of memory concerning past events, as well as a lack in ability to create new memories. While this spans across many subsets of memory, such as recognition, recall, and autobiographical memory, there seems to be a lesser impact on musical memory in those with Alzheimer’s. Multiple studies have suggested that exposure to music and introduction of music therapy can even improve other aspects of memory in Alzheimer’s patients. This systematic review and meta-analysis sought to examine the relationship between music exposure and autobiographical memory specifically. A pool of electronic …


Investigation Into The Comorbidities Of Disordered Eating And Social Anxiety Disorder In College Students, Alice Mccraney May 2022

Investigation Into The Comorbidities Of Disordered Eating And Social Anxiety Disorder In College Students, Alice Mccraney

Honors Theses

In recent years, psychiatrists have reported a trend that individuals with social anxiety disorders are more likely to also have disordered eating and vice versa. Research into this connection has suggested that risk factors, such as stress reactivity, negative self- esteem, perfectionism and fear of negative evaluation are potential links. This is important because understanding the correlation between the two disorders could help develop better treatments plans for people who suffer from these disorders. This study investigates the relationship between the two. A total of 257 college students between ages 18-22 completed a questionnaire using the Disordered Eating Attitude Scale …


Mindfulness And Physical Activity As Moderators Of Behavioral Inhibition Sensitivity And Psychological Distress, Edward Silber Mar 2022

Mindfulness And Physical Activity As Moderators Of Behavioral Inhibition Sensitivity And Psychological Distress, Edward Silber

LSU Master's Theses

Framed in Reinforcement Sensitivity Theory, the current study examined the moderating effects of mindfulness and moderate-to-vigorous physical activity (MVPA) on the relationship between behavioral inhibition system (BIS) sensitivity and psychological distress. Participants (N=183) were college students at a large public university in the Southeastern United States. Data were collected using an online survey with self-report questionnaires that demonstrated acceptable reliability. Data analysis utilized multiple linear regression models to test study hypotheses. Findings revealed a significant positive relationship between BIS sensitivity and psychological distress, with mindfulness and MVPA significantly moderating this association. Specifically, increased reports of mindfulness and MVPA …


Reducing Fear Overgeneralization With Safety Learning: Attention Bias As A Moderator, Boyang Fan Feb 2022

Reducing Fear Overgeneralization With Safety Learning: Attention Bias As A Moderator, Boyang Fan

Dissertations, Theses, and Capstone Projects

Anxiety disorders are the most prevalent mental health condition and affect one out of nine individuals around the world. Fear generalization is a neurocognitive mechanism thought to maintain and exacerbate anxiety, and thus is an important target of therapeutic interventions. Yet, intervention research and practice place relatively little emphasis on its importance. Given that a significant proportion of individuals do not respond to extant treatments of anxiety disorders, a strengthened focus on fear generalization may inform the development and personalization of new treatment approaches. Recent notions have linked fear generalization to failures in distinguishing between signals that predict the occurrence …


Parent-Prompted Dysregulation: Do Parents Serve As Cues For Dysregulation In Some Children?, Daniel Lee Jan 2022

Parent-Prompted Dysregulation: Do Parents Serve As Cues For Dysregulation In Some Children?, Daniel Lee

Pitzer Senior Theses

Children occasionally encounter dysregulation when interacting with their parents in relatively neutral or positive scenarios. Given that the cause of dysregulation is usually relational, meaning it is often cued by someone who is seen to have power or control over the person, children could be particularly susceptible to dysregulation in the presence of their parents. However, when examining the existing literature, there appeared to be a lack of research and knowledge concerning this topic, with much of the literature focusing on the effect of child stressors on parental dysregulation. As a result, the term parent-prompted dysregulation was developed to refer …


The Predictive Influence Of Challenging Behavior On Parent Stress In Young Children With Autism Spectrum Disorder, Paige Weir Nov 2021

The Predictive Influence Of Challenging Behavior On Parent Stress In Young Children With Autism Spectrum Disorder, Paige Weir

LSU Master's Theses

Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by deficits in social communication, restricted interest, and repetitive patterns of behavior. Individuals with ASD also exhibit challenging behaviors that affect parent and caregiver stress directly. However, researchers have not yet examined the predictive influence of specific challenging behaviors on parent stress, particularly in young children (i.e., infants and toddlers) with ASD. Therefore, the current study expands existing literature by a) investigating the influence that challenging behaviors of young children with ASD have on parent stress and b) examining the unique contribution that each behavior (i.e., aggressive/disruptive behavior, stereotypy, and self-injurious …


A Randomized Controlled Trial Of Psychological Outcomes Of Mobile Guided Resonant Frequency Breathing In Young Adults With Elevated Stress During The Covid-19 Pandemic, Al Amira Safa Shehab Sep 2021

A Randomized Controlled Trial Of Psychological Outcomes Of Mobile Guided Resonant Frequency Breathing In Young Adults With Elevated Stress During The Covid-19 Pandemic, Al Amira Safa Shehab

Dissertations, Theses, and Capstone Projects

Deep breathing practices have shown promise in reducing stress, anxiety, and depression in different populations, including young adults. Specifically, resonant frequency breathing can exert an impact on stress response systems through the vagus nerve and the hypothalamo-pituitary-adrenal (HPA) axis. This may induce reductions in stress and improvement in emotion regulation. Young adults, including college students, tend to be at a higher risk for psychological distress, as they face several psychosocial challenges. The COVID-19 pandemic has imposed new and unique stressors that resulted in higher levels of stress and emotional symptoms and it has been shown that this may have placed …


Does Aberrant Connectivity Underlie The Experience Of Misophonia?, Kate Raymond Aug 2021

Does Aberrant Connectivity Underlie The Experience Of Misophonia?, Kate Raymond

Electronic Thesis and Dissertation Repository

Misophonia is a condition characterized by an extreme aversion to certain ordinary sounds, such as chewing or breathing. These sounds are typically innocuous but elicit strong feelings of anger, anxiety, and disgust as well as physiological stress in people with misophonia. This misophonic reaction to “trigger” sounds is also marked by increased activity in regions of the brain that process sound, ascribe salience, and regulate emotion (Kumar et al., 2017; Schroder et al., 2019). It has therefore been theorized that aberrant connectivity between these brain regions (particularly the anterior insula, auditory cortex, amygdala, and hippocampus) may underlie the experience of …


Altered Network Organization And Screen Time Use In Childhood Attention-Deficit / Hyperactivity Disorder (Adhd), Elizabeth Jane Hawkey Aug 2021

Altered Network Organization And Screen Time Use In Childhood Attention-Deficit / Hyperactivity Disorder (Adhd), Elizabeth Jane Hawkey

Arts & Sciences Electronic Theses and Dissertations

Introduction: Symptoms of attention-deficit/hyperactivity disorder (ADHD) have been associated with alterations in functional connectivity involving networks in the developing brain that support optimal cognitive control. However, a clear profile of altered connectivity has yet to emerge, and it remains unclear whether changes in behavioral patterns such as screen time (ST) contribute to ADHD symptomatology and altered connectivity in networks that support cognitive control. The current study examined connectivity between large-scale networks associated with cognitive control (CC), measures of executive function (EF) which index CC, and ST in children with ADHD. Methods: Our sample included 11,874 children (ages 9-11, 52% male) …


Having A High-Activity Catechol-O-Methyltransferase Allele Is Associated With Elevated Anxiety And Lower Salivary Dehydroepiandrosterone But Also Lower Alpha Amylase In Children With Chromosome 22q11.2 Deletion Syndrome., Jessie Beebe Aug 2021

Having A High-Activity Catechol-O-Methyltransferase Allele Is Associated With Elevated Anxiety And Lower Salivary Dehydroepiandrosterone But Also Lower Alpha Amylase In Children With Chromosome 22q11.2 Deletion Syndrome., Jessie Beebe

University of New Orleans Theses and Dissertations

Chromosome 22q11.2 deletion syndrome (22q11.2DS) results from a hemizygous deletion located on the long arm of chromosome 22. The most common deletion sizes affect between 30 and 90 genes. Individuals with 22q11.2DS may develop serious developmental and psychiatric disorders. The phenotype is highly variable, however, and may be influenced by allelic variation of the retained copies of genes covered by the deletion. I set out to examine the effects of two genes, catechol-O-methyltransferase (COMT) and proline dehydrogenase (PRODH), in relation to anxiety in children and adolescents with 22q11.2DS. Individuals with the major COMT allele (higher activity) have significantly higher anxiety …


Resting State Functional Connectivity In The Default Mode Network: Relationships Between Cannabis Use, Gender, And Cognition In Adolescents And Young Adults, Megan Ritchay Aug 2021

Resting State Functional Connectivity In The Default Mode Network: Relationships Between Cannabis Use, Gender, And Cognition In Adolescents And Young Adults, Megan Ritchay

Theses and Dissertations

Introduction: Cannabis is the most commonly used illicit substance in the United States, and nearly 1 in 4 young adults are current cannabis users. The psychoactive component of cannabis, THC, is active at cannabinoid receptors, type 1, or CB1 receptors. CB1 receptors play a critical role in neural development, and chronic cannabis use causes desensitization and downregulation of these receptors. Chronic cannabis use is associated with changes in resting state functional connectivity (RSFC) in the default mode network (DMN) in adolescents and young adults, although results are somewhat inconsistent across studies, likely due to differing methodologies. Additionally, cannabis effects appear …


Cerebellum-Seeded Functional Connectivity Changes In Trait-Anxious Individuals Undergoing Attention Bias Modification Training, Katherine Elwell Jul 2021

Cerebellum-Seeded Functional Connectivity Changes In Trait-Anxious Individuals Undergoing Attention Bias Modification Training, Katherine Elwell

All NMU Master's Theses

Anxiety and anxiety related disorders are increasing at a drastic rate in the past decade, with the NIMH reporting that 31.1% of U.S. adults will experience an anxiety disorder at some point in their lives. Anxiety is commonly characterized by increased attention bias to threat. Attention Bias Modification (ABM) is a new treatment used to reduce individual’s attention bias towards threat. The extent to which ABM leads to underlying neural changes is still unknown. The cerebellum is a neglected brain structure, with new research provides evidence that cerebellum’s functional connectivity and shared networks with threat processing regions has a direct …


Learning To Feel Safe: A Translational Study Of The Influence Of Safety Learning On Anxiety-Related Overgeneralized Fear, Hyein Cho Jun 2021

Learning To Feel Safe: A Translational Study Of The Influence Of Safety Learning On Anxiety-Related Overgeneralized Fear, Hyein Cho

Dissertations, Theses, and Capstone Projects

Anxiety disorders are among the most common mental health diagnoses, affecting about a third of the population in their lifetime. However, approximately a third of individuals with anxiety do not respond to current treatment approaches, highlighting the need to identify additional potential therapeutic mechanisms. Safety learning is one such mechanism, but methodological challenges and a dearth of research have prevented the field from advancing the understanding of the role of safety learning in the etiology and remediation of anxiety disorders. Animal research, using single-cued safety learning paradigms, has yielded promising early findings, demonstrating that safety learning directly reduces anxiety-related behaviors …