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Full-Text Articles in Social and Behavioral Sciences
Intermolecular Addition Reactions Of N-Acyliminium Ions (Part I), Arife Yazici, Stephen G. Pyne
Intermolecular Addition Reactions Of N-Acyliminium Ions (Part I), Arife Yazici, Stephen G. Pyne
Faculty of Science - Papers (Archive)
This review highlights the advances in the literature up to July 2008 on the intermolecular reactions of acyclic and cyclic N-acyliminium ions. This is an update of an earlier review in 2000 on this topic and does not include intramolecular addition reactions to N-acyliminium ions which was recently reviewed. This review is presented in two parts, with the first part dealing with acyclic and pyrrolidinone-based N-acyliminium ions. Part II continues with other five-membered heterocyclic derivatives and higher systems.
What I Have Done, What Was Done To Me: Confession And Testimony In Stolen Life: Journey Of A Cree Woman, Michael Jacklin
What I Have Done, What Was Done To Me: Confession And Testimony In Stolen Life: Journey Of A Cree Woman, Michael Jacklin
Faculty of Arts - Papers (Archive)
Yvonne Johnson’s life narrative, written over a six-year period in collaboration with Rudy Wiebe, tells the story of how Johnson came to be the only First Nations woman in Canada serving a life-twenty-five sentence for first degree murder. Stolen Life: Journey of a Cree Woman (1998) relates the circumstances of Johnson’s involvement with three others – Dwayne Wenger, Ernest Jensen and Shirley Anne Salmon – in the killing of Leonard Charles Skwarok in Wetaskiwin, Alberta, in 1989. In a night of excessive drinking, the two men and two women participated in the confinement, beating, sexual abuse, strangulation and killing of …
Beta-2 Glycoprotein I And Its Role In Antiphospholipid Syndrome: Lessons From Knockout Mice, Spyridon Miyakis, Sarah A. Robertson, S A. Krilis
Beta-2 Glycoprotein I And Its Role In Antiphospholipid Syndrome: Lessons From Knockout Mice, Spyridon Miyakis, Sarah A. Robertson, S A. Krilis
Faculty of Science, Medicine and Health - Papers: part A
The antiphospholipid syndrome is characterized by the presence in serum of autoantibodies against h2GPI. Although the role of h2GPI in the pathogenesis of antiphospholipid antibody syndrome (APS) is well recognized, its exact physiological functions still remain undisclosed. Several interactions of h2GPI with components of the coagulation cascade have been proposed, resulting in both procoagulant and anticoagulant effects. Additionally, h2GPI has been implicated in the mechanism of recurrent fetal loss entailed in APS. Recently, using a homologous recombination approach, reproduction of mice homozygous for deletion of the b2GPI gene has been feasible. h2GPI knockout mice offer a valuable tool for revealing …
'I Don't Really Know, So It's A Guess': Women's Reasons For Breast Cancer Risk Estimation., Nancy Humpel, Sandra C. Jones
'I Don't Really Know, So It's A Guess': Women's Reasons For Breast Cancer Risk Estimation., Nancy Humpel, Sandra C. Jones
Faculty of Social Sciences - Papers (Archive)
Women of all ages have been found to overestimate both the incidence and the mortality rate from breast cancer and the reasons for this are unclear. A qualitative study asked eighty three women (mean age = 44 years) how likely they thought they were to get breast cancer and to explain the reasoning behind their choice. Based on their responses, women's perceptions were categorised as: no risk (5%); reasonably accurate (30%); overestimated (22%); and greatly overestimated (43%). Four main themes emerged from the reasons given: 'Don't know/guess', 'family history' of breast cancer, 'age' related reasoning, and making their decision from …
Evolution Of Sfbi Encoding Streptococcal Fibronectin-Binding Protein I: Horizontal Genetic Transfer And Gene Mosaic Structure, Rebecca J. Towers, Peter K. Fagan, Susanne R. Talay, Bart J. Currie, Kadaba S. Sriprakash, Mark J. Walker, Gursharan S. Chhatwal
Evolution Of Sfbi Encoding Streptococcal Fibronectin-Binding Protein I: Horizontal Genetic Transfer And Gene Mosaic Structure, Rebecca J. Towers, Peter K. Fagan, Susanne R. Talay, Bart J. Currie, Kadaba S. Sriprakash, Mark J. Walker, Gursharan S. Chhatwal
Faculty of Science, Medicine and Health - Papers: part A
Streptococcal fibronectin-binding protein is an important virulence factor involved in colonization and invasion of epithelial cells and tissues by Streptococcus pyogenes. In order to investigate the mechanisms involved in the evolution of sfbI, the sfbI genes from 54 strains were sequenced. Thirty-four distinct alleles were identified. Three principal mechanisms appear to have been involved in the evolution of sfbI. The amino-terminal aromatic amino acid-rich domain is the most variable region and is apparently generated by intergenic recombination of horizontally acquired DNA cassettes, resulting in a genetic mosaic in this region. Two distinct and divergent sequence types that …
Characterization Of The Domain Of Fibronectin-Binding Protein Of I Of Streptococcus Pyogenes Responsible For Elicitation Of A Protective Immune Response, Kai Schulze, Eva Medina, Susanne R. Talay, Rebecca J. Towers, Gursharan S. Chhatwal, Carlos A. Guzman
Characterization Of The Domain Of Fibronectin-Binding Protein Of I Of Streptococcus Pyogenes Responsible For Elicitation Of A Protective Immune Response, Kai Schulze, Eva Medina, Susanne R. Talay, Rebecca J. Towers, Gursharan S. Chhatwal, Carlos A. Guzman
Faculty of Science, Medicine and Health - Papers: part A
Fibronectin-binding protein I (SfbI) represents a major adhesin ofStreptococcus pyogenes. Mice were intranasally immunized with recombinant proteins spanning different portions of SfbI to identify the minimal fragment able to elicit a protective response against a lethal challenge with S. pyogenes. The strongest cellular responses and the highest levels of antigen-specific secretory immunoglobulin A (IgA) were detected in mice immunized with the fibronectin-binding region of SfbI. In contrast, animals vaccinated with a polypeptide spanning the aromatic and proline-rich regions showed the highest titers and fastest IgG response in serum. Vaccination with either SfbI without a membrane anchor and …
'I Think Condoms Are Good But, Aai, I Hate Those Things': Condom Use Among Adolescents And Young People In A Southern African Township, Catherine L. Mac Phail, Catherine Campbell
'I Think Condoms Are Good But, Aai, I Hate Those Things': Condom Use Among Adolescents And Young People In A Southern African Township, Catherine L. Mac Phail, Catherine Campbell
Faculty of Social Sciences - Papers (Archive)
Levels of heterosexually transmitted HIV infection are high amongst South African youth, with one recent survey reporting levels of 18.9% amongst 17-20 year olds and 43.1% amongst 21-25 year olds. In these groups levels of knowledge about HIV are high, but perceived vulnerability and reported condom use are low. Much existing research into youth HIV in developing countries relies on survey measures which use individual knowledge, attitudes and reported behaviour as variables in seeking to explain HIV transmission amongst this group. This paper reports on a focus group study that seeks to complement existing individual-level quantitative findings with qualitative findings …
Benang: From The Heart: 'I Found Myself Among Paper', Lisa Slater
Benang: From The Heart: 'I Found Myself Among Paper', Lisa Slater
Faculty of Arts - Papers (Archive)
In his first novel True Country. Kim Scon esrablished himself as a writer who is determi ned to investigate the continued traumatic effects of colonial violence. Harley, the protagonist of Scott's second novel Benang: from the Heart (thc co-winner of the Miles Franklin award), takes up a pen in response to reductionist assimilationist records. He states: But I found myself among paper, words not formed by an intention corresponding to my own, and I read a world weak in creative spirit.
What Do I Do With The Rest Of The Class? The Nature Of Teaching Learning Activities, Brian L. Cambourne
What Do I Do With The Rest Of The Class? The Nature Of Teaching Learning Activities, Brian L. Cambourne
Faculty of Social Sciences - Papers (Archive)
Cambourne discusses using teaching-learning activities that revolve around the use of small groups. He relates how teachers can keep the rest of their class productively engaged in learning as the teacher works with individuals or small groups.