Design of Experiments and Sample Surveys Commons^™

Nonparametric Tests For Replicated Latin Squares, Joseph Yang

Dissertations

Two classes of nonparametric procedures for a replicated Latin square design that test for both general and increasing alternatives are developed. The two classes of procedures are similar in the sense that both transform the data so that existing well-known tests for randomized complete block designs can be utilized. On the other hand, the two classes differ in the way that the data is transformed - one class essentially aggregates the data while the other class aligns the data. Within these contexts, the exact distributions and asymptotic distributions are discussed, when applicable. The exact distributions are easily computed using the …

Orthogonal Arrays And Legendre Pairs, Kristopher N. Kilpatrick

Theses and Dissertations

Well-designed experiments greatly improve test and evaluation. Efficient experiments reduce the cost and time of running tests while improving the quality of the information obtained. Orthogonal Arrays (OAs) and Hadamard matrices are used as designed experiments to glean as much information as possible about a process with limited resources. However, constructing OAs and Hadamard matrices in general is a very difficult problem. Finding Legendre pairs (LPs) results in the construction of Hadamard matrices. This research studies the classification problem of OAs and the existence problem of LPs. In doing so, it makes two contributions to the discipline. First, it improves …

Experimental Design On High-Speed Sliding Wear, Irene D. Liew

Theses and Dissertations

The purpose of this research is to develop, conduct, and analyze an experimental design that characterizes wear rates of various materials sliding at high speeds along AISI 4340 steel. This work is in support of Holloman Air Force Base, which is invested in engineering a more wear-resistant rocket slipper for its high-speed test track. This research uses a design of experiments approach to systematically identify and evaluate potential slipper attributes that mitigate wear according to a heat transfer model. Final findings include recommendations of slipper materials that theoretically perform similar to or better than the baseline Vascomax®C300 maraging steel material. …

Tuning Optimization Software Parameters For Mixed Integer Programming Problems, Toni P. Sorrell

Theses and Dissertations

The tuning of optimization software is of key interest to researchers solving mixed integer programming (MIP) problems. The efficiency of the optimization software can be greatly impacted by the solver’s parameter settings and the structure of the MIP. A designed experiment approach is used to fit a statistical model that would suggest settings of the parameters that provided the largest reduction in the primal integral metric. Tuning exemplars of six and 59 factors (parameters) of optimization software, experimentation takes place on three classes of MIPs: survivable fixed telecommunication network design, a formulation of the support vector machine with the ramp …

The Usefulness Of Systematic Reviews Of Animal Experiments For The Design Of Preclinical And Clinical Studies, Rob B.M. De Vries, Kimberley E. Weaver, Marc T. Avey, Martin Stephens, Emily S. Sena, Marlies Leenaars

Martin Stephens, PhD

The question of how animal studies should be designed, conducted, and analyzed remains underexposed in societal debates on animal experimentation. This is not only a scientific but also amoral question. After all, if animal experiments are not appropriately designed, conducted, and analyzed, the results produced are unlikely to be reliable and the animals have in effect been wasted. In this article, we focus on one particular method to address this moral question, namely systematic reviews of previously performed animal experiments. We discuss how the design, conduct, and analysis of future (animal and human) experiments may be optimized through such systematic …

Empirical Evaluation Of Different Features Of Design In Confirmatory Factor Analysis, Deyab Almaleki

Dissertations

Factor analysis (FA) is the study of variance within a group. Within-subject variance (WSV) is affected by multiple features in a study context, such as: the study experimental design (ED) and sampling design (SD), thus anything that influences or changes variance may affect the conclusions related to FA.

The aim of this study was to provide empirical evaluation of the influence of different aspects of ED and SD on WSV in the context of FA in terms of model precision and model estimate stability. Four Monte Carlo population correlation matrices were hypothesized based on different communality magnitudes (high, moderate, low, …

The Usefulness Of Systematic Reviews Of Animal Experiments For The Design Of Preclinical And Clinical Studies, Rob B.M. De Vries, Kimberley E. Weaver, Marc T. Avey, Martin Stephens, Emily S. Sena, Marlies Leenaars

Experimentation Collection

The question of how animal studies should be designed, conducted, and analyzed remains underexposed in societal debates on animal experimentation. This is not only a scientific but also amoral question. After all, if animal experiments are not appropriately designed, conducted, and analyzed, the results produced are unlikely to be reliable and the animals have in effect been wasted. In this article, we focus on one particular method to address this moral question, namely systematic reviews of previously performed animal experiments. We discuss how the design, conduct, and analysis of future (animal and human) experiments may be optimized through such systematic …

Some Problems And Solutions In The Experimental Science Of Technology: The Proper Use And Reporting Of Statistics In Computational Intelligence, With An Experimental Design From Computational Ethnomusicology, Mehmet Vurkaç

Systems Science Friday Noon Seminar Series

Statistics is the meta-science that lends validity and credibility to The Scientific Method. However, as a complex and advanced Science in itself, Statistics is often misunderstood and misused by scientists, engineers, medical and legal professionals and others. In the area of Computational Intelligence (CI), there have been numerous misuses of statistical techniques leading to the publishing of insupportable results, which, in addition to being a problem in itself, has also contributed to a degree of rift between the Statistics/Statistical Learning community and the Machine Learning/Computational Intelligence community. This talk surveys a number of misuses of statistical inference in CI settings, …

Design Considerations For Efficient And Effective Microarray Studies, M. Kathleen Kerr

UW Biostatistics Working Paper Series

This paper describes the theoretical and practical issues in experimental design for gene expression microarrays. Specifically, this paper (1) discusses the basic principles of design (randomization, replication, and blocking) as they pertain to microarrays, and (2) provides some general guidelines for statisticians designing microarray studies.

A Messy, But Instructive, Case Study In Design Of Experiments, Leroy A. Franklin, Belva J. Cooley, Gary Elrod

Mathematical Sciences Technical Reports (MSTR)

A company manufacturing fans wished to conduct an experimental design to determine the best combination of three factors affecting the breaking torque of the fans. Analysis of the data ceased to be straightforward when the authors found that the data failed the test for homogeneity of variances. After unsuccessfully attempting to transform the data and thereby meet the assumptions necessary to carry on the analysis, the authors relied upon a graphical analysis and a careful study of the means for each design point. This paper describes a statistically sound but novel strategy used to complete the analysis.