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Condensed Matter Physics Commons

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Full-Text Articles in Condensed Matter Physics

Intramolecular Cross-Linking Of Beta Subunits And Pegylation Of Bovine Stroma Free Hemoglobin For Use As A Hemoglobin Based Oxygen Carrier, Gil Salazar Apr 2016

Intramolecular Cross-Linking Of Beta Subunits And Pegylation Of Bovine Stroma Free Hemoglobin For Use As A Hemoglobin Based Oxygen Carrier, Gil Salazar

GS4 Georgia Southern Student Scholars Symposium

Purified Bovine Stroma-Free Hemoglobin's (BSFHb) two beta subunits where intramolecularly cross-linked (BXLHb) using bis(3,5-dibromosalicyl) fumarate (DBBF) and further modified with Polyethylene glycol (BPEGXLHb) for possible use as a Hemoglobin Based Oxygen Carrier (HBOC). Each stage of modification was characterized by size exclusion chromatography and fluorescence methods. We prepared several different molar ratios of DBBF and BSFHb to acquire the highest yield of BXLHb. Cross-linking of the beta subunits will stabilize the whole Hb tetramer from dissociation and prevent unwanted degradation of the HBOC. We prepared a sample modified with PEG (PEGylation) that had a molecular weight of 5kDa. PEGylation increases …


Stereographic Visualization Of Bose-Einstein Condensate Clouds To Measure The Gravitational Constant, Ed Wesley Wells Jan 2016

Stereographic Visualization Of Bose-Einstein Condensate Clouds To Measure The Gravitational Constant, Ed Wesley Wells

Electronic Theses and Dissertations

This thesis describes a set of tools that can be used for the rapid design of atom interferometer schemes suitable for measuring Newton's Universal Gravitation constant also known as "Big G". This tool set is especially applicable to Bose--Einstein--condensed systems present in NASA's Cold Atom Laboratory experiment to be deployed to the International Space Station in 2017. These tools include a method of approximating the solutions of the nonlinear Schrödinger or Gross--Pitaevskii equation (GPE) using the Lagrangian Variational Method. They also include a set of software tools for translating the approximate solutions of the GPE into images of the optical …