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Life Sciences

2011

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Articles 1 - 25 of 25

Full-Text Articles in Physics

Mathematical Modeling Of Peristaltic Flow Of Chyme In Small Intestine, Daniel N. Riahi, Ranadhir Roy Dec 2011

Mathematical Modeling Of Peristaltic Flow Of Chyme In Small Intestine, Daniel N. Riahi, Ranadhir Roy

Applications and Applied Mathematics: An International Journal (AAM)

Mathematical models based on axisymmetric Newtonian incompressible fluid flow are studied for the peristaltic flow of chyme in the small intestines, which is an axisymmetric cylindrical tube. The flow is modeled more realistically modeled by assuming that the peristaltic rush wave is a non-periodic mode composed of two sinusoidal waves of different wavelengths, which propagate at the same speed along the outer boundary of the tube. Both cases of flow in a tube and in an annulus that are modeled and investigated in the present paper correspond respectively to the cases of flow of chyme in the small intestine in …


Photolithographic Surface Micromachining Of Polydimethylsiloxane (Pdms), Weiqiang Chen, Raymond H. W. Lam, Jianping Fu Nov 2011

Photolithographic Surface Micromachining Of Polydimethylsiloxane (Pdms), Weiqiang Chen, Raymond H. W. Lam, Jianping Fu

Weiqiang Chen

A major technical hurdle in microfluidics is the difficulty in achieving high fidelity lithographic patterning on polydimethylsiloxane (PDMS). Here, we report a simple yet highly precise and repeatable PDMS surface micromachining method using direct photolithography followed by reactive ion etching (RIE). Our method to achieve surface patterning of PDMS applied an O2 plasma treatment to PDMS to activate its surface to overcome the challenge of poor photoresist adhesion on PDMS for photolithography. Our photolithographic PDMS surface micromachining technique is compatible with conventional soft lithography techniques and other silicon-based surface and bulk micromachining methods. To illustrate the general application of our …


Evolution Of Spur-Length Diversity In Aquilegia Petals Is Achieved Solely Through Cell-Shape Anisotropy, Joshua R. Puzey, Sharon J. Gerbode, Scott A. Hodges, Elena M. Kramer, L. Mahadevan Nov 2011

Evolution Of Spur-Length Diversity In Aquilegia Petals Is Achieved Solely Through Cell-Shape Anisotropy, Joshua R. Puzey, Sharon J. Gerbode, Scott A. Hodges, Elena M. Kramer, L. Mahadevan

All HMC Faculty Publications and Research

The role of petal spurs and specialized pollinator interactions has been studied since Darwin. Aquilegia petal spurs exhibit striking size and shape diversity, correlated with specialized pollinators ranging from bees to hawkmoths in a textbook example of adaptive radiation. Despite the evolutionary significance of spur length, remarkably little is known about Aquilegia spur morphogenesis and its evolution. Using experimental measurements, both at tissue and cellular levels, combined with numerical modelling, we have investigated the relative roles of cell divisions and cell shape in determining the morphology of the Aquilegia petal spur. Contrary to decades-old hypotheses implicating a discrete meristematic zone …


Schrödinger And Nietzsche On Life: The Eternal Recurrence Of The Same, Babette Babich Sep 2011

Schrödinger And Nietzsche On Life: The Eternal Recurrence Of The Same, Babette Babich

Working Papers

Schrödinger and Nietzsche on Life: The Eternal Recurrence of the Same

This essay explores Schrödinger’s reflections on measurement, consciousness, and personal identity. Schrödinger’s, What Is Life? is read together with Nietzsche’s own reflections on the same question, in his aphorism What is Life? together with Nietzsche’s teaching of the eternal return of the selfsame. Schrödinger’s own thinking is influenced as is Nietzsche’s by Schopenhauer but Schrödinger also has the Vedic tradition as this influenced Schopenhauer himself in view.


Exploring Bacterial Nanowires: From Properties To Functions And Implications, Kar Man Leung Aug 2011

Exploring Bacterial Nanowires: From Properties To Functions And Implications, Kar Man Leung

Electronic Thesis and Dissertation Repository

The discovery of electrically conductive bacterial nanowires from a broad range of microbes provides completely new insights into microbial physiology. Shewanella oneidensis strain MR-1, a dissimilatory metal-reducing bacterium, produces extracellular bacterial nanowires up to tens of micrometers long, with a lateral dimension of ~10 nm. The Shewanella bacterial nanowires are efficient electrical conductors as revealed by scanning probe techniques such as CP-AFM and STM.

Direct electrical transport measurements along Shewanella nanowires reveal a measured nanowire resistivity on the order of 1 Ω∙cm. With electron transport rates up to 109/s at 100 mV, bacterial nanowires can serve as a …


Six Types Of Multistability In A Neuronal Model Based On Slow Calcium Current, Tatiana Malashchenko, Andrey Shilnikov, Gennady Cymbalyuk Jul 2011

Six Types Of Multistability In A Neuronal Model Based On Slow Calcium Current, Tatiana Malashchenko, Andrey Shilnikov, Gennady Cymbalyuk

Neuroscience Institute Faculty Publications

Background: Multistability of oscillatory and silent regimes is a ubiquitous phenomenon exhibited by excitable systems such as neurons and cardiac cells. Multistability can play functional roles in short-term memory and maintaining posture. It seems to pose an evolutionary advantage for neurons which are part of multifunctional Central Pattern Generators to possess multistability. The mechanisms supporting multistability of bursting regimes are not well understood or classified.

Methodology/Principal Findings: Our study is focused on determining the bio-physical mechanisms underlying different types of co-existence of the oscillatory and silent regimes observed in a neuronal model. We develop a low-dimensional model typifying the dynamics …


Adaptation And Stochasticity Of Natural Complex Systems, Roy David Dar May 2011

Adaptation And Stochasticity Of Natural Complex Systems, Roy David Dar

Doctoral Dissertations

The methods that fueled the microscale revolution (top-down design/fabrication, combined with application of forces large enough to overpower stochasticity) constitute an approach that will not scale down to nanoscale systems. In contrast, in nanotechnology, we strive to embrace nature’s quite different paradigms to create functional systems, such as self-assembly to create structures, exploiting stochasticity, rather than overwhelming it, in order to create deterministic, yet highly adaptable, behavior. Nature’s approach, through billions of years of evolutionary development, has achieved self-assembling, self-duplicating, self-healing, adaptive systems. Compared to microprocessors, nature’s approach has achieved eight orders of magnitude higher memory density and three orders …


Impact Of The Solvent Capacity Constraint On E. Coli Metabolism, Alexei Vazquez, Qasim Beg, Marcio Demenezes, Jason Ernst, Ziv Bar-Joseph, Albert-László Barabási, László Boros, Zoltán Oltvai Jan 2011

Impact Of The Solvent Capacity Constraint On E. Coli Metabolism, Alexei Vazquez, Qasim Beg, Marcio Demenezes, Jason Ernst, Ziv Bar-Joseph, Albert-László Barabási, László Boros, Zoltán Oltvai

Albert-László Barabási

Background: Obtaining quantitative predictions for cellular metabolic activities requires the identification and modeling of the physicochemical constraints that are relevant at physiological growth conditions. Molecular crowding in a cell's cytoplasm is one such potential constraint, as it limits the solvent capacity available to metabolic enzymes. Results: Using a recently introduced flux balance modeling framework (FBAwMC) here we demonstrate that this constraint determines a metabolic switch in E. coli cells when they are shifted from low to high growth rates. The switch is characterized by a change in effective optimization strategy, the excretion of acetate at high growth rates, and a …


Using Adi To Quantify A Color Change In Crayfish, Jennifer Welborn Jan 2011

Using Adi To Quantify A Color Change In Crayfish, Jennifer Welborn

STEM Digital

Do Crayfish Change Color If Their Environment Changes? A Guided Inquiry Lab for 7th grade Life Science

Background: There is anecdotal evidence from bass fisherman that crayfish are able to change color depending on their surroundings. A (cursory) literature review of this phenomenon showed that no formal research has been done in this area. Students had an additional informal lesson about research funding (or lack thereof) because of this finding.

Students designed and conducted a controlled experiment to see the effect of changing environment color on crayfish color.

ADI was used to quantify a color change.


Arsenic Project Topics, Julian Tyson Jan 2011

Arsenic Project Topics, Julian Tyson

STEM Digital

How do analytical chemists make light work in tracking potentially harmful chemicals?


A Cell Electrofusion Microfluidic Device Integrated With 3d Thin-Film Microelectrode Arrays, Ning Hu, Jun Yang, Shizhi Qian, Sang W. Joo, Xiaolin Zheng Jan 2011

A Cell Electrofusion Microfluidic Device Integrated With 3d Thin-Film Microelectrode Arrays, Ning Hu, Jun Yang, Shizhi Qian, Sang W. Joo, Xiaolin Zheng

Mechanical & Aerospace Engineering Faculty Publications

A microfluidic device integrated with 3D thin film microelectrode arrays wrapped around serpentine-shaped microchannel walls has been designed, fabricated and tested for cell electrofusion. Each microelectrode array has 1015 discrete microelectrodes patterned on each side wall, and the adjacent microelectrodes are separated by coplanar dielectric channel wall. The device was tested to electrofuse K562 cells under a relatively low voltage. Under an AC electric field applied between the pair of the microelectrode arrays, cells are paired at the edge of each discrete microelectrode due to the induced positive dielectrophoresis. Subsequently, electric pulse signals are sequentially applied between the microelectrode arrays …


President's Message, Justin K. Wyatt Jan 2011

President's Message, Justin K. Wyatt

Journal of the South Carolina Academy of Science

No abstract provided.


Scas Officers And Council Members 2010 - 2011 Jan 2011

Scas Officers And Council Members 2010 - 2011

Journal of the South Carolina Academy of Science

No abstract provided.


Properties And Uses Of Sodium Titanates And Peroxotitanates, David Hobbs Jan 2011

Properties And Uses Of Sodium Titanates And Peroxotitanates, David Hobbs

Journal of the South Carolina Academy of Science

No abstract provided.


Scas Officers And Council Members 2010-2011 Jan 2011

Scas Officers And Council Members 2010-2011

Journal of the South Carolina Academy of Science

No abstract provided.


Epoxi: Comet 103p/Hartley 2 Observations From A Worldwide Campaign ; Astrophysical Journal Letters, K. Meech, M. A'Hearn, J. Adams, P. Bacci, J. Bai, L. Barrera, M. Battelino, J. Bauer, E. Becklin, B. Bhatt, N. Biver, D. Bockelee-Morvan, D. Bodewits, H. Bohnhardt, J. Boissier, B. Bonev, W. Borghini, J. Brucato, E. Bryssinck, M. Buie, H. Canovas, D. Castellano, S. Charnley, W. Chen, P. Chiang, Y. Choi, D. Christian, Y. Chuang, Anita Cochran, P. Colom, M. Combi, I. Coulson, J. Crovisier, N. Russo, K. Dennerl, K. Dewahl, M. Disanti, M. Facchini, T. Farnham, Y. Fernandez, H. Floren, U. Frisk, T. Fujiyoshi, R. Furusho, T. Fuse, G. Galli, D. Garcia-Hernandez, A. Gersch, Z. Getu Jan 2011

Epoxi: Comet 103p/Hartley 2 Observations From A Worldwide Campaign ; Astrophysical Journal Letters, K. Meech, M. A'Hearn, J. Adams, P. Bacci, J. Bai, L. Barrera, M. Battelino, J. Bauer, E. Becklin, B. Bhatt, N. Biver, D. Bockelee-Morvan, D. Bodewits, H. Bohnhardt, J. Boissier, B. Bonev, W. Borghini, J. Brucato, E. Bryssinck, M. Buie, H. Canovas, D. Castellano, S. Charnley, W. Chen, P. Chiang, Y. Choi, D. Christian, Y. Chuang, Anita Cochran, P. Colom, M. Combi, I. Coulson, J. Crovisier, N. Russo, K. Dennerl, K. Dewahl, M. Disanti, M. Facchini, T. Farnham, Y. Fernandez, H. Floren, U. Frisk, T. Fujiyoshi, R. Furusho, T. Fuse, G. Galli, D. Garcia-Hernandez, A. Gersch, Z. Getu

Physics Faculty Works

Earth- and space-based observations provide synergistic information for space mission encounters by providing data over longer timescales, at different wavelengths and using techniques that are impossible with an in situ flyby. We report here such observations in support of the EPOXI spacecraft flyby of comet 103P/Hartley 2. The nucleus is small and dark, and exhibited a very rapidly changing rotation period. Prior to the onset of activity, the period was ~16.4 hr. Starting in 2010 August the period changed from 16.6 hr to near 19 hr in December. With respect to dust composition, most volatiles and carbon and nitrogen isotope …


Physical Models Of Amyloid Fibril Assembly, Shannon Elizabeth Hill Jan 2011

Physical Models Of Amyloid Fibril Assembly, Shannon Elizabeth Hill

USF Tampa Graduate Theses and Dissertations

Formation of large fibers and plaques by amyloid proteins is recognized as the molecular hallmark of an increasing number of human disorders, including Parkinson's disease, Alzheimer's disease and even type II diabetes. The broader objective of my research is to unravel the basic mechanisms that initiate and regulate fibril formation by amyloidogenic proteins. This objective is significant because even basic aspects of how fibril formation proceeds from a soluble, monomeric protein to an insoluble amyloid fibril remain much debated. Furthermore, there is increasingly strong evidence suggesting that intermediates of the aggregation process, with properties distinct from those of mature fibrils, …


Table Of Contents Jan 2011

Table Of Contents

Journal of the South Carolina Academy of Science

No abstract provided.


Effect Of Substrate Composition And Alignment On Corneal Cell Phenotype, Donna Phu '09, Lindsay S. Wray '08, Robert V. Warren '10, Richard C. Haskell, Elizabeth J. Orwin Jan 2011

Effect Of Substrate Composition And Alignment On Corneal Cell Phenotype, Donna Phu '09, Lindsay S. Wray '08, Robert V. Warren '10, Richard C. Haskell, Elizabeth J. Orwin

All HMC Faculty Publications and Research

Corneal blindness is a significant problem treated primarily by corneal transplants. Donor tissue supply is low, creating a growing need for an alternative. A tissue-engineered cornea made from patient-derived cells and biopolymer scaffold materials would be widely accessible to all patients and would alleviate the need for donor sources. Previous work in this lab led to a method for electrospinning type I collagen scaffolds for culturing corneal fibroblasts ex vivo that mimics the microenvironment in the native cornea. This electrospun scaffold is composed of small-diameter, aligned collagen fibers. In this study, we investigate the effect of scaffold nanostructure and composition …


A Study Of Complex Systems: From Magnetic To Biological, Douglas Carroll Lovelady Jan 2011

A Study Of Complex Systems: From Magnetic To Biological, Douglas Carroll Lovelady

USF Tampa Graduate Theses and Dissertations

This work is a study of complex many-body systems with non-trivial interactions. Many such systems can be described with models that are much simpler than the real thing but which can still give good insight into the behavior of realistic systems. We take a look at two such systems. The first part looks at a model that elucidates the variety of magnetic phases observed in rare-earth heterostructures at low temperatures: the six-state clock model. We use an ANNNI-like model Hamiltonian that has a three dimensional parameter space and yields two-dimensional multiphase regions in this space. A low-temperature expansion of the …


Laser-Induced Breakdown Spectroscopy (Libs): An Innovative Tool For Studying Bacteria, Qassem I. Mohaidat Jan 2011

Laser-Induced Breakdown Spectroscopy (Libs): An Innovative Tool For Studying Bacteria, Qassem I. Mohaidat

Wayne State University Dissertations

Laser-induced breakdown spectroscopy (LIBS) has gained a reputation as a flexible and convenient technique for rapidly determining the elemental composition of samples with minimal or no sample preparation. In this dissertation, I will describe the benefits of using LIBS for the rapid discrimination and identification of bacteria (both pathogenic and non-pathogenic) based on the relative concentration of trace inorganic elements such as Mg, P, Ca, and Na. The speed, portability, and robustness of the technique suggest that LIBS may be applicable as a rapid point-of-care medical diagnostic technology.

LIBS spectra of multiple genera of bacteria such as Escherichia, Streptococcus, Mycobacterium, …


Table Of Contents Jan 2011

Table Of Contents

Journal of the South Carolina Academy of Science

No abstract provided.


Removal And Sequestration Of Iodide From Alkaline Solutions Using Silver-Doped Carbon Nanotubes, Adrian L. Pishko, Steven M. Serkiz, Apparao M. Rao Jan 2011

Removal And Sequestration Of Iodide From Alkaline Solutions Using Silver-Doped Carbon Nanotubes, Adrian L. Pishko, Steven M. Serkiz, Apparao M. Rao

Journal of the South Carolina Academy of Science

No abstract provided.


Table Of Contents, David D. Nolte Dec 2010

Table Of Contents, David D. Nolte

David D Nolte


Light is at once the most sensitive and the most gentle probe of matter.  It is commonplace for light to measure a picometer displacement far below the nanometer scale of atoms, or to capture the emission of a single photon from a fluorescent dye molecule.  Light is easy to generate using light-emitting diodes or lasers, and to detect using ultrasensitive photodetectors as well as the now ubiquitous digital cameras.  Light also has the uncanny ability to penetrate living tissue harmlessly and deeply, while capturing valuable information on the health and function of cells.  For these reasons, light has become an …


Epoxi: Comet 103p/Hartley 2 Observations From A Worldwide Campaign ; Astrophysical Journal Letters, K. J. Meech, M. F. A'Hearn, J. A. Adams, P. Bacci, J. Bai, L. Barrera, M. Battelino, J. M. Bauer, E. Becklin, B. Bhatt, N. Biver, D. Bockelee-Morvan, D. Bodewits, H. Bohnhardt, J. Boissier, B. P. Bonev, W. Borghini, J. R. Brucato, E. Bryssinck, M. W. Buie, H. Canovas, D. Castellano, S. B. Charnley, W. P. Chen, P. Chiang, Y. J. Choi, D. J. Christian, Y. L. Chuang, Anita L. Cochran, P. Colom, M. R. Combi, I. M. Coulson, J. Crovisier, N. Dello Russo, K. Dennerl, K. Dewahl, M. A. Disanti, M. Facchini, T. L. Farnham, Y. Fernandez, H. G. Floren, U. Frisk, T. Fujiyoshi, R. Furusho, T. Fuse, G. Galli, D. A. Garcia-Hernandez, A. Gersch, Z. Getu Dec 2010

Epoxi: Comet 103p/Hartley 2 Observations From A Worldwide Campaign ; Astrophysical Journal Letters, K. J. Meech, M. F. A'Hearn, J. A. Adams, P. Bacci, J. Bai, L. Barrera, M. Battelino, J. M. Bauer, E. Becklin, B. Bhatt, N. Biver, D. Bockelee-Morvan, D. Bodewits, H. Bohnhardt, J. Boissier, B. P. Bonev, W. Borghini, J. R. Brucato, E. Bryssinck, M. W. Buie, H. Canovas, D. Castellano, S. B. Charnley, W. P. Chen, P. Chiang, Y. J. Choi, D. J. Christian, Y. L. Chuang, Anita L. Cochran, P. Colom, M. R. Combi, I. M. Coulson, J. Crovisier, N. Dello Russo, K. Dennerl, K. Dewahl, M. A. Disanti, M. Facchini, T. L. Farnham, Y. Fernandez, H. G. Floren, U. Frisk, T. Fujiyoshi, R. Furusho, T. Fuse, G. Galli, D. A. Garcia-Hernandez, A. Gersch, Z. Getu

Erika Gibb

Earth- and space-based observations provide synergistic information for space mission encounters by providing data over longer timescales, at different wavelengths and using techniques that are impossible with an in situ flyby. We report here such observations in support of the EPOXI spacecraft flyby of comet 103P/Hartley 2. The nucleus is small and dark, and exhibited a very rapidly changing rotation period. Prior to the onset of activity, the period was ~16.4 hr. Starting in 2010 August the period changed from 16.6 hr to near 19 hr in December. With respect to dust composition, most volatiles and carbon and nitrogen isotope …