Inorganic Chemistry Commons^™

Mechanistic Investigation Of C—C Bond Activation Of Phosphaalkynes With Pt(0) Complexes, Roberto M. Escobar, Abdurrahman C. Ateşin, Christian Müller, William D. Jones, Tülay Ateşin

Research Symposium

Carbon–carbon (C–C) bond activation has gained increased attention as a direct method for the synthesis of pharmaceuticals. Due to the thermodynamic stability and kinetic inaccessibility of the C–C bonds, however, activation of C–C bonds by homogeneous transition-metal catalysts under mild homogeneous conditions is still a challenge. Most of the systems in which the activation occurs either have aromatization or relief of ring strain as the primary driving force. The activation of unstrained C–C bonds of phosphaalkynes does not have this advantage. This study employs Density Functional Theory (DFT) calculations to elucidate Pt(0)-mediated C–CP bond activation mechanisms in phosphaalkynes. Investigating the …

Alkylthiocarbamate Metal Complexes With Antiproliferation Activity., Kritika Bajaj

Electronic Theses and Dissertations

Bis(thiosemicarbazones) (BTSCs) and their metal complexes have been extensively studied for various applications including catalysis for hydrogen evolution reactions, treatment of neurodegenerative diseases, hypoxia imaging, and a wide range of pharmacological purposes including antitumor, antiviral, antibacterial, and antifungal agents. The paramount property that makes BTSC metal complexes interesting for their use in these applications is the reduction potential of the coordinated metal, which can be selectively tuned by varying the substituents present on the ligand framework. Although the BTSCs have shown a great deal of success as potential cancer therapeutic agents, they lack selectivity towards cancer cells. For this matter, …

Metal Complexes Of Bis(Pyrazolyl)Methane-Based Ditopic Ligands, Pubudu Nuwan Perera Hapuarachchige

Masters Theses

No abstract provided.

Synthesis And Characterization Of Starburst Pseudorotaxanes And Their Metallic Derivatives, Shalini D. Kadinappulige

Masters Theses

Mechanically Interlocked Molecules (MIMs) are interlocked molecular architectures, characterized by the fact that they are linked through a mechanical bond. Catenanes, rotaxanes, molecular knots, and Borromean rings are typical examples for these molecules. Since MIMs are not connected by covalent bonds, hydrogen bonding, π- π stacking, and/or electrostatic interactions help bring the components together. Dialkyl-ammonium centers, bis(pyridinium)ethane dications, viologen species, and naphthalenediimide π-deficient groups are well known as recognition motifs for crown ethers. In the research described here, we have synthesized several pseudorotaxanes and their tricyclohexyltin metallic derivatives, based on benzobis(imidazolium) (BBI) salts as axles, in combination with the 15DN38C10 …

Bimetallic Complexes: The Fundamental Aspects Of Metal-Metal Interactions, Ligand Sterics And Application, Michael Bernard Pastor

University of the Pacific Theses and Dissertations

Metal containing complexes have been used to catalyze various organic transformations for the past few decades. The success of several mononuclear catalysts led to transition metal catalysts used in pharmaceuticals, environmental, and industrial processes. While mononuclear complexes have been used extensively, bimetallic systems have received far less attention. Bimetallic or polynuclear sites are commonly found in metalloenzymes that perform elegant transformation in biological systems, underlying their significance. Inorganic chemists take inspiration from nature and design model bimetallic complexes to further study this cooperativity effect. A bimetallic platform offers many structural and functional differences such as the identity of the metal …

Homo- And Heterometallic Bis(Pentafluorobenzoyl)Methanide Complexes Of Copper(Ii) And Cobalt(Ii), Janell Crowder

Legacy Theses & Dissertations (2009 - 2024)

β-Diketones are well known to form metal complexes with practically every known metal and metalloid. Metal complexes of fluorinated β-diketones generally exhibit increased volatility and thermal stability compared to the non-fluorinated analogues, and thus are used extensively in various chemical vapor deposition (CVD) processes for the deposition of metal, simple or mixed metal oxides, and fluorine-doped metal oxide thin films. Furthermore, the electron-withdrawing nature of the fluorinated ligand enhances the Lewis acidity of a coordinatively unsaturated metal center which facilitates additional coordination reactions. The physical and structural properties of fluorinated β-diketonate complexes are discussed in Chapter 1 …

Mixed Ligand Approach To Design Heterometallic Single-Source Precursors For Low-Temperature Preparation Of Oxide Materials, Craig Matthew Lieberman

Legacy Theses & Dissertations (2009 - 2024)

There is a considerable interest in the use of metal oxides for development of novel high-technological materials such as gas sensors, multiferroics, and electrocatalysts. In particular, the design of complex oxides, which incorporate more than one type of metal atom, is focused on enriching chemical and physical properties of the target materials and allowing for increased functionality. In order to replace the harsh conditions associated with traditional synthetic routes that often require high temperatures and/or pressures, new soft chemistry methods for the preparation of mixed-metal oxide materials have been developed. One of the most promising directions is the emergence of …

Enhanced Structural Support Of Metal Sites As Nodes In Metal-Organic Frameworks Compared To Metal Complexes, Sanjit Das

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Crystalline porous materials have gained long-standing interest for their application in gas storage, separation and catalysis. These materials have been useful for domestic, scientific and industrial purposes for many decades. Zeolites are a well known example of such materials.

Metal-organic frameworks are a new class of crystalline porous materials. They have many advantages over the more widely known zeolites. Though metal-organic frameworks are relatively new, their basic structure, known as the secondary building unit, very closely resembles the structure of metal complexes. Such metal complexes have been characterized in chemistry for more than a century.

Chemical catalysis is a process …

Developing Dimetal Paddlewheel Complexes For Catalytic Applications, Margaret E. Napier

Legacy Theses & Dissertations (2009 - 2024)

Although there are countless examples of rhodium-catalyzed organic reactions in the chemical literature, the field continues to develop at a steady pace, as focus shifts taking advantage of economy of resources while maintaining efficiency of the catalytic reactions. The work presented is separated into three chapters, with each describing a specific approach to the development of new materials which can provide either a direct economy of resources and reagents or can be used for heterogenization of catalytic systems.

Bowl-Shaped Polyaromatic Hydrocarbons (Buckybowls) : Crystal Packing And Metal Binding Reactions, Alexander S. Filatov

Legacy Theses & Dissertations (2009 - 2024)

This work is a part of a broad program in our laboratory dedicated to the investigation of a new class of non-planar polyaromatic hydrocarbons that map onto the surfaces of fullerenes (and referred to as buckybowls). It focuses on the preparation of buckybowls, their molecular and solid state structures, and reactivity in metal binding reactions. For the first time, the structures of all available buckybowls have been analyzed using X-ray diffraction data collected in the course of this work, as well as data previously obtained in our group or reported by others (and dearchived from the Cambridge Structural Database). Forces …

In-Vivo Delivery Of Dna Vaccines Using Metallo-Lipid Nanoparticles, Clarissa Sara Gomez

Open Access Theses & Dissertations

There has been a rapidly growing area of research in the design and synthesis of molecules that self-organize in water to form functional nanosystems and due to the high interest in the area metal ligand complexes were tested as drug delivery systems with a Leishmania vaccine. Herein, we present the design, synthesis and functional activity of Cu(II) and Zn(II) complexes that self-assemble in water to form spherical nanoscale structures that exhibit an affinity to bind DNA and deliver it into eukaryotic cells with a high percent efficiency in-vitro. In order to assess the effectiveness of these nanoparticles to deliver DNA …

Synthesis And Reactivity Of Gold Thiolate Cluster Complexes, Hanan Abdou

Electronic Theses and Dissertations

Chemical oxidation of dinuclear gold(I) thiolates of the formula LLAu₂(SC₆H₄CH₃)₂ [LL= dppp, bis(dipheny1phosphine)propane and dppb, bis(dipheny1phosphine)butane] and dinuclear gold(I) thiolate complexes with bridging a propane dithiolate ligand of the formula LLAu₂(SC₃H₆S) [LL = dppp and dppb] was carried out using the mild oxidizing agent, ferrocenium, [Cp₂Fe]PF6). Spectroscopic studies and elemental analysis showed the formation of gold(I) clusters, disulfide, and ferrocene as products of this oxidation reaction. The clusters, [(dppp)AU₂(SC₆H₄CH₃)](PF₆) and [(dppb)Au₂(SC …