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Full-Text Articles in Inorganic Chemistry
Spectroscopic Investigation Into The Heme Binding And The Heme Degradation By Mycobacterium Tuberculosis Mhud, Biswash Thakuri
Spectroscopic Investigation Into The Heme Binding And The Heme Degradation By Mycobacterium Tuberculosis Mhud, Biswash Thakuri
Graduate College Dissertations and Theses
MhuD is a heme degrading enzyme found across mycobacteria. In the heme uptake machinery of Mycobacterium Tuberculosis, MhuD is a heme oxygenase (HO) involved in catalyzing the degradation of heme. Canonical HOs, such as human HO, have been shown to degrade heme to non-heme iron, carbon monoxide (CO) and biliverdin. However, MhuD has been demonstrated to degrade heme to non-heme iron and mycobilin without the release of CO. Formation of a novel chromophore by MhuD revealed that it follows a unique heme degradation mechanism compared to that of canonical HOs. Binding of heme to MhuD is the first step in …
Investigations Of Pnictogen And Boron-Group Compounds Towards The Synthesis Of Group Iii/V Pre-Ceramic Molecules, Brandon James Ackley
Investigations Of Pnictogen And Boron-Group Compounds Towards The Synthesis Of Group Iii/V Pre-Ceramic Molecules, Brandon James Ackley
Graduate College Dissertations and Theses
Semiconductor ceramics have been the subject of study for many years due to their usefulness in applications ranging from LED devices to computer chips. Despite the ubiquity of semiconductor ceramics in daily life, the synthesis and manufacturing of such devices is tedious, energy intensive, or have a high potential for danger. Manufacturing methods such as deposition require the use of toxic or pyrophoric gases as well as requiring the temperatures often exceeding 1,000 °C. One way to address the issues of toxicity and high thermal barriers can be found in the implementation of pre-ceramic materials; materials which are either molecular …