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Full-Text Articles in Analytical Chemistry
The Analysis Of Cyanide And Its Breakdown Products In Biological Samples, Brian A. Logue, Diane M. Hinkens, Steven I. Baskin, Gary A. Rockwood
The Analysis Of Cyanide And Its Breakdown Products In Biological Samples, Brian A. Logue, Diane M. Hinkens, Steven I. Baskin, Gary A. Rockwood
Brian Logue
Cyanide is a toxic chemical that may be introduced into living organisms as a result of natural processes and/or anthropogenic uses (legal or illicit). Exposure to cyanide can be verified by analysis of cyanide or one of its breakdown products from biological samples. This verification may be important for medical, law-enforcement, military, forensic, research, or veterinary purposes. This review will discuss current bioanalytical techniques used for the verification of cyanide exposure, identify common problems associated with the analysis of cyanide and its biological breakdown products, and briefly address the metabolism and toxicokinetics of cyanide and its breakdown products in biological …
Silicone Wristbands As Passive Samplers For Quantitative Measurement Of Wood Smoke Exposure, Hannah J. Wright
Silicone Wristbands As Passive Samplers For Quantitative Measurement Of Wood Smoke Exposure, Hannah J. Wright
Graduate Student Theses, Dissertations, & Professional Papers
Human exposure to biomass smoke is a health concern worldwide. Although many studies have measured particulate matter in wood smoke as a health concern, exposure to mutagenic and carcinogenic volatile and semivolatile compounds remains understudied. This research introduces a novel method of quantitative measurement of exposure to these compounds using silicone wristbands. The study developed a method to extract analytes of interest from the wristbands and quantify a few volatile organic compounds and polycyclic aromatic hydrocarbons with known ill health effects, and then performed linear regressions between extracted levels and exposure to those analytes using controlled exposure studies. Results indicate …