Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Organic Chemistry (12)
- Analytical Chemistry (8)
- Engineering (5)
- Materials Chemistry (5)
- Polymer Chemistry (5)
-
- Inorganic Chemistry (4)
- Medicine and Health Sciences (4)
- Physical Chemistry (4)
- Environmental Chemistry (3)
- Environmental Sciences (3)
- Life Sciences (3)
- Materials Science and Engineering (3)
- Atomic, Molecular and Optical Physics (2)
- Chemicals and Drugs (2)
- Medicinal-Pharmaceutical Chemistry (2)
- Other Materials Science and Engineering (2)
- Physics (2)
- Structural Materials (2)
- Sustainability (2)
- Biochemistry (1)
- Biochemistry, Biophysics, and Structural Biology (1)
- Catalysis and Reaction Engineering (1)
- Chemical Engineering (1)
- Computer Sciences (1)
- Data Science (1)
- Education (1)
- Educational Assessment, Evaluation, and Research (1)
- Fluid Dynamics (1)
- Institution
- Keyword
-
- Cancer (3)
- Energy storage (2)
- Glioblastoma (2)
- Materials (2)
- Metal (2)
-
- Polymers (2)
- Synthesis (2)
- (Bisdiisopropylphospino)ethanehane (1)
- 1-perfluoroheptene (1)
- 2D-NMR of isosorbide (1)
- 5-Fluorouracil (1)
- AHR airway hyperresponsiveness (1)
- AP-4 4-Aminopyridine (1)
- ARN14988 (1)
- ARN14988-M (1)
- ASM airway smooth muscle (1)
- AUC area under curve (1)
- Abuse potential (1)
- Ach acetylcholine (1)
- Acid Ceramidase Inhibitor (1)
- Activated biochar (1)
- Adsorption (1)
- Alkylating agent (1)
- Alleneamide (1)
- Analytical chemistry (1)
- Anion Exchange (1)
- Antibiotics (1)
- Anticancer drugs (1)
- Assessment Validity Issues (1)
- Atmospheric science (1)
Articles 61 - 66 of 66
Full-Text Articles in Chemistry
Molten Salt Technologies For Advanced Nuclear Fuel Cycles And Molten Salt Reactors, Dimitris Killinger
Molten Salt Technologies For Advanced Nuclear Fuel Cycles And Molten Salt Reactors, Dimitris Killinger
Theses and Dissertations
This dissertation provides five topics—an assessment of different monitoring and analytical techniques often cited in the literature for molten salt systems and designs for nuclear engineering applications. First, we explored commonly used materials for quasi-reference electrodes in molten chloride salts. Second, the limitations of the electrochemical analysis known as cyclic voltammetry due to the concentration of uranium(III) present were being investigated. Third, we provided an experimental assessment on the development of a spectroelectrochemical cell for interrogating various spectroelectrochemical techniques, namely chronoabsorptometry and chronofluorometry, and their limitations due to the presence of uranium(III) ions. Fourth, a study on the corrosion resistance …
Antiviral Effects Of Metalloshielding: Differential Antiviral Activity Of Polynuclear Platinum And Cobalt Compounds, Mary Zoepfl
Antiviral Effects Of Metalloshielding: Differential Antiviral Activity Of Polynuclear Platinum And Cobalt Compounds, Mary Zoepfl
Theses and Dissertations
The majority of antiviral drug development has focused on virus-specific discovery targeting discrete steps in the individual life cycles. Although great strides have been made for a number of clinically relevant diseases such as human immunodeficiency virus, influenza virus, and hepatitis B, broad spectrum antivirals do not exist. Broad spectrum antivirals would offer (1) treatment for viruses without specifically-targeted antivirals, (2) treatment for viruses which have developed resistance to their available treatments, and (3) a rapidly deployable treatment option in viral epidemics. Many viruses including human cytomegalovirus (HCMV), HIV, and SARS-CoV-2. rely on heparan sulfate (HS), a highly sulfated glycosaminoglycan …
Metal Nanoparticle Synthesis Via Laser-Induced Photochemical Reduction Of Metal Salts, Laysa M. Frias Batista
Metal Nanoparticle Synthesis Via Laser-Induced Photochemical Reduction Of Metal Salts, Laysa M. Frias Batista
Theses and Dissertations
Significant attention has been focused on metal nanoparticles (MNPs) due to their unique optical, catalytic, and electronic properties. In the last two decades, laser synthesis techniques have emerged as versatile routes to MNPs that enable control over particle size, shape, and surface chemistry without the use of chemical reducing agents or surface-blocking capping ligands. A method gaining increasing attention is the direct laser-driven reduction of metal salts, called Laser Reduction in Liquid (LRL). LRL typically involves the use of intense laser pulses of picosecond or femtosecond duration to ionize and dissociate solvent molecules, generating plasmas with reactive chemical species such …
Synthesis And Modeling Of Manganese Ferrite Nanoparticles For Magnetic Hyperthermia Applications, Margaret E. Thornton
Synthesis And Modeling Of Manganese Ferrite Nanoparticles For Magnetic Hyperthermia Applications, Margaret E. Thornton
Theses and Dissertations
Biologically targeted magnetic hyperthermia (MH) is a promising cancer therapeutic that is both non-invasive and has the potential to serve as a single-modality cancer treatment. MH operates through the elevation of temperatures between 40-43 °C to induce apoptosis in malignant tumor cells, while the small size of the magnetic nanoparticles preserves the healthy surrounding tissue. At present, MH is limited by low heating efficiency and heterogenous outcomes, and treatment requires direct-injection of the nanoparticles, excluding deep-tissue and metastatic tumors from the therapy. The most popular candidates for MH are the spinel ferrites iron oxide and manganese iron oxide (MFO). These …
Behavioral Screening And Chiral Bioanalysis Of Emerging Stimulant-Type Drugs In Rats, Tyson R. Baird
Behavioral Screening And Chiral Bioanalysis Of Emerging Stimulant-Type Drugs In Rats, Tyson R. Baird
Theses and Dissertations
The epidemic of drug use in the United States and elsewhere in the world has resulted in tragic loss of life and substantial economic costs. Novel psychoactive substances (NPS) are one of the contributors to this problem, and the lack of information about many of these drugs compounds their risk. This dissertation proposes a strategy to use intracranial self-stimulation (ICSS) as a behavioral screening tool to assess emerging drugs of abuse for their abuse potential in order to generate a proactive threat assessment. A series of stimulant-type drugs including methcathinone, α-pyrrolidinohexanophenone (α-PHP), cocaine, and the phenyltropane analogs of cocaine WIN35428 …
Asymmetric Cuh-Catalyzed Reductive Coupling Of Alleneamides With Carbonyl Electrophiles And The Mechanistic Investigation Into The Suzuki-Miyaura Cross-Couplings Of Electron-Deficient Systems, Samantha L. Gargaro
Theses and Dissertations
Most natural products and other biologically active small molecules contain multiple stereogenic heteroatoms throughout their carbon scaffold. As a result, methods to install these multi-heteroatom functionalities efficiently are highly desirable. Reductive coupling reactions have been studied extensively, and reductive allylation has been a key method for generating chiral secondary and tertiary allylic alcohols. This work focuses on utilizing naturally abundant and inexpensive Cu for the asymmetric reductive coupling of alleneamides with carbonyl electrophiles to access highly functionalized multi-heteroatom scaffolds that are difficult to produce via traditional methods. Described herein are methods for these asymmetric reductive coupling reactions. Chapter 1 describes …