Open Access. Powered by Scholars. Published by Universities.®

Articles 1 - 30 of 51

Full-Text Articles in Ordinary Differential Equations and Applied Dynamics

Modeling Fast Information And Slow(Er) Disease Spreading: A Geometric Analysis, Iulia Martina Bulai, Mattia Sensi, Sara Sottile May 2024

Modeling Fast Information And Slow(Er) Disease Spreading: A Geometric Analysis, Iulia Martina Bulai, Mattia Sensi, Sara Sottile

Biology and Medicine Through Mathematics Conference

No abstract provided.


Information Feedback Delays Within Epidemic Models And Their Effect On Model Dynamics., Maria K. Bouka, Christopher Strickland Dr May 2024

Information Feedback Delays Within Epidemic Models And Their Effect On Model Dynamics., Maria K. Bouka, Christopher Strickland Dr

Biology and Medicine Through Mathematics Conference

No abstract provided.


Modeling An Infection Outbreak With Quarantine: The Sibkr Model, Mikenna Dew, Amanda Langosch, Theadora Baker-Wallerstein Apr 2024

Modeling An Infection Outbreak With Quarantine: The Sibkr Model, Mikenna Dew, Amanda Langosch, Theadora Baker-Wallerstein

Rose-Hulman Undergraduate Mathematics Journal

Influenza is a respiratory infection that places a substantial burden in the world population each year. In this project, we study and interpret a data set from a flu outbreak in a British boarding school in 1978 with mathematical modeling. First, we propose a generalization of the SIR model based on the quarantine measure in place and establish the long-time behavior of the model. By analyzing the model mathematically, we determine the analytic formulas of the basic reproduction number, the long-time limit of solutions, and the maximum number of infection population. Moreover, we estimate the parameters of the model based …


A Tale Of Two Viruses: Why Smallpox Was Eradicated And Polio Persists, Katherine G. Mcgough, Erin N. Bodine Jan 2024

A Tale Of Two Viruses: Why Smallpox Was Eradicated And Polio Persists, Katherine G. Mcgough, Erin N. Bodine

Spora: A Journal of Biomathematics

The smallpox and poliomyelitis (polio) viruses were, at a time, one of the largest threats to global public health killing millions until global eradication campaigns were put into effect. Vaccination led to the eradication of smallpox and the elimination of polio for most of the world. However, polio continues to persist at endemic levels in Pakistan and Afghanistan. We developed ODE models of smallpox and polio to explore differences in transmission dynamics and determine if the underlying biology has made poliomyelitis more difficult to eradicate. Our model analysis shows there are multiple factors which should allow polio to have a …


An Ode Model For Investigating The Sleep-Pain Relationship In Sickle Cell Disease, Quindel Jones, Angela Reynolds, Rebecca Segal, Reginald Mcgee Nov 2023

An Ode Model For Investigating The Sleep-Pain Relationship In Sickle Cell Disease, Quindel Jones, Angela Reynolds, Rebecca Segal, Reginald Mcgee

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Physics-Informed Neural Networks For Agent-Based Epidemiological Model Calibration, Alvan C. Arulandu, Padmanabhan Seshaiyer Nov 2023

Physics-Informed Neural Networks For Agent-Based Epidemiological Model Calibration, Alvan C. Arulandu, Padmanabhan Seshaiyer

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Modeling Immune System Dynamics During Hiv Infection And Treatment With Differential Equations, Nicole Rychagov Apr 2023

Modeling Immune System Dynamics During Hiv Infection And Treatment With Differential Equations, Nicole Rychagov

CODEE Journal

An inquiry-based project that discusses immune system dynamics during HIV infection using differential equations is presented. The complex interactions between healthy T-cells, latently infected T-cells, actively infected T-cells, and the HIV virus are modeled using four nonlinear differential equations. The model is adapted to simulate long term HIV dynamics, including the AIDS state, and is used to simulate the long term effects of the traditional antiretroviral therapy (ART). The model is also used to test viral rebound over time of combined application of ART and a new drug that blocks the reactivation of the viral genome in the infected cells …


Physics-Informed Neural Networks For Informed Vaccine Distribution In Heterogeneously Mixed Populations, Alvan Arulandu, Padmanabhan Seshaiyer Nov 2022

Physics-Informed Neural Networks For Informed Vaccine Distribution In Heterogeneously Mixed Populations, Alvan Arulandu, Padmanabhan Seshaiyer

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Humanizing Mathematical Biology Research And Education, Carrie Diaz Eaton, Ognyan Simeonov Nov 2022

Humanizing Mathematical Biology Research And Education, Carrie Diaz Eaton, Ognyan Simeonov

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


The Effect Of Vaccine Misinformation On Disease Spread, Anthony Delegge, Yina Wang Nov 2022

The Effect Of Vaccine Misinformation On Disease Spread, Anthony Delegge, Yina Wang

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Stochastic Models Of Zoonotic Avian Influenza With Multiple Hosts, Environmental Transmission, And Migration In The Natural Reservoir, Kaia Smith Nov 2022

Stochastic Models Of Zoonotic Avian Influenza With Multiple Hosts, Environmental Transmission, And Migration In The Natural Reservoir, Kaia Smith

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


The Effect Of Prep Uptake And Adherence On The Spread Of Hiv In The Presence Of Casual And Long-Term Partnerships, Sylvia J. Gutowska, Katharine Gurski, Kathleen Hoffman May 2022

The Effect Of Prep Uptake And Adherence On The Spread Of Hiv In The Presence Of Casual And Long-Term Partnerships, Sylvia J. Gutowska, Katharine Gurski, Kathleen Hoffman

Biology and Medicine Through Mathematics Conference

No abstract provided.


Modeling, Analysis And Simulation Of Covid-19 Interaction Dynamics Between Local Community In Saudi Arabia And Visiting Sub-Population, Manal Badgaish, Padmanabhan Seshaiyer Nov 2021

Modeling, Analysis And Simulation Of Covid-19 Interaction Dynamics Between Local Community In Saudi Arabia And Visiting Sub-Population, Manal Badgaish, Padmanabhan Seshaiyer

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Mathematical Modeling, Analysis, And Simulation Of The Covid-19 Pandemic With Behavioral Patterns And Group Mixing, Comfort Ohajunwa, Padmanabhan Seshaiyer Jul 2021

Mathematical Modeling, Analysis, And Simulation Of The Covid-19 Pandemic With Behavioral Patterns And Group Mixing, Comfort Ohajunwa, Padmanabhan Seshaiyer

Spora: A Journal of Biomathematics

Due to the rise of COVID-19 cases, many mathematical models have been developed to study the disease dynamics of the virus. However, despite its role in the spread of COVID-19, many SEIR models neglect to account for human behavior. In this project, we develop a novel mathematical modeling framework for studying the impact of mixing patterns and social behavior on the spread of COVID-19. Specifically, we consider two groups, one exhibiting normal behavior who do not reduce their contacts and another exhibiting altered behavior who reduce their contacts by practicing non-pharmaceutical interventions such as social distancing and self-isolation. The dynamics …


Predicting Tumor Response To Radiotherapy Based On Estimation Of Non-Treatment Parameters, Yutian Huang, Allison L. Lewis Apr 2021

Predicting Tumor Response To Radiotherapy Based On Estimation Of Non-Treatment Parameters, Yutian Huang, Allison L. Lewis

Spora: A Journal of Biomathematics

Though clinicians can now collect detailed information about a variety of tumor characteristics as a tumor evolves, it remains difficult to predict the efficacy of a given treatment prior to administration. Additionally, the process of data collection may be invasive and expensive. Thus, the creation of a framework for predicting patient response to treatment using only information collected prior to the start of treatment could be invaluable. In this study, we employ ordinary differential equation models for tumor growth and utilize synthetic data from a cellular automaton model for calibration. We investigate which parameters have the most influence upon treatment …


Long-Term Dynamics Of The Kidney Disease Epidemic Among Hiv-Infected Individuals, Heather Gudaz, Henry A. Ogu, Elissa J. Schwartz Feb 2021

Long-Term Dynamics Of The Kidney Disease Epidemic Among Hiv-Infected Individuals, Heather Gudaz, Henry A. Ogu, Elissa J. Schwartz

Spora: A Journal of Biomathematics

One of many risks facing HIV+ individuals is the development of kidney dysfunction and end stage kidney disease (ESKD). A differential equation-based mathematical model was developed to assess the impact of antiretroviral therapy on the progression to kidney disease and on reducing mortality due to kidney failure. Analytical and numerical predictions of long-term HIV+ ESKD prevalence show that therapy can lead to either extremely low levels of disease prevalence or increased prevalence, depending on drug efficacy levels and mechanisms of action. Maintenance of HIV+ ESKD prevalence below one individual is possible with sufficient efficacy (e.g., 99%) against the progression from …


Applying Immuno-Epidemiology Principles To Violence, Anna H. Sisk, Nina H. Fefferman, Judy Day, Patricia Bamwine Nov 2020

Applying Immuno-Epidemiology Principles To Violence, Anna H. Sisk, Nina H. Fefferman, Judy Day, Patricia Bamwine

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Analyzing The Control Measures For The Homeless Population And Quantifying Their Impact On The Covid-19 Epidemic In New York City, Steven Manns Nov 2020

Analyzing The Control Measures For The Homeless Population And Quantifying Their Impact On The Covid-19 Epidemic In New York City, Steven Manns

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Mathematical Modeling And Analysis Of The Zika Virus Epidemic With Human Mobility And Parameter Estimation For Localities In Puerto Rico, Carmen Caiseda Nov 2020

Mathematical Modeling And Analysis Of The Zika Virus Epidemic With Human Mobility And Parameter Estimation For Localities In Puerto Rico, Carmen Caiseda

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Mathematical Modeling, Analysis, And Simulation Of The Covid-19 Pandemic With Behavioral Patterns, Risk Perception, And Group Mixing, Comfort Ohajunwa, Padmanabhan Seshaiyer Nov 2020

Mathematical Modeling, Analysis, And Simulation Of The Covid-19 Pandemic With Behavioral Patterns, Risk Perception, And Group Mixing, Comfort Ohajunwa, Padmanabhan Seshaiyer

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


In Silico Modelling For The Treatment Of Gastric Cancer, Leonardo F. Martinez, Diana Gamboa, Paul A. Valle Nov 2020

In Silico Modelling For The Treatment Of Gastric Cancer, Leonardo F. Martinez, Diana Gamboa, Paul A. Valle

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Using Network Modeling To Understand The Relationship Between Sars-Cov-1 And Sars-Cov-2, Elizabeth Brooke Haywood, Nicole A. Bruce May 2020

Using Network Modeling To Understand The Relationship Between Sars-Cov-1 And Sars-Cov-2, Elizabeth Brooke Haywood, Nicole A. Bruce

Biology and Medicine Through Mathematics Conference

No abstract provided.


Modeling The Effects Of Fentanyl And Narcan On The Opioid Epidemic In Allegheny County Using Mathematics, Lindsay Moskal, Lauren Sines, Rachael Neilan Ph.D. May 2020

Modeling The Effects Of Fentanyl And Narcan On The Opioid Epidemic In Allegheny County Using Mathematics, Lindsay Moskal, Lauren Sines, Rachael Neilan Ph.D.

Undergraduate Research and Scholarship Symposium

Starting in the 1990s, physicians across the United States have increasingly prescribed opioid pain relievers, which has given rise to the current opioid epidemic. As a result, there has been a drastic increase in the number of overdose fatalities. In 2017, the number of opioid overdose deaths peaked and the U.S. declared the crisis as a public health emergency. One state that has contributed significantly to this epidemic is Pennsylvania, which ranks first for the greatest number of overdose deaths and third for the highest death rate. In fact, Allegheny County has witnessed an overdose death rate that is three …


Modeling The Effects Of Fentanyl And Narcan On The Opioid Epidemic In Allegheny County Using Mathematics, Lindsay Moskal, Lauren Sines, Rachael Neilan Ph.D. May 2020

Modeling The Effects Of Fentanyl And Narcan On The Opioid Epidemic In Allegheny County Using Mathematics, Lindsay Moskal, Lauren Sines, Rachael Neilan Ph.D.

Undergraduate Research and Scholarship Symposium

Starting in the 1990s, physicians across the United States have increasingly prescribed opioid pain relievers, which has given rise to the current opioid epidemic. As a result, there has been a drastic increase in the number of overdose fatalities. In 2017, the number of opioid overdose deaths peaked and the U.S. declared the crisis as a public health emergency. One state that has contributed significantly to this epidemic is Pennsylvania, which ranks first for the greatest number of overdose deaths and third for the highest death rate. In fact, Allegheny County has witnessed an overdose death rate that is three …


A Study Of Cholera Transmission, Urmi Ghosh-Dastidar Apr 2020

A Study Of Cholera Transmission, Urmi Ghosh-Dastidar

Open Educational Resources

A recent cholera outbreak in Haiti brought public attention to this disease. Cholera, a diarrheal disease, is caused by an intestinal bacterium, and if not addressed in a timely manner may become fatal. During the project described here, the students will learn how to solve and address a practical problem such as cholera transmission using various mathematical tools. Students will learn to develop a differential equation model based on practical scenarios, analyze the model using mathematics as well as numerical simulation, and finally describe the results in words that are understandable by the people who are not specialists in this …


Evaluation Of Age- And Risk-Based Mass Drug Administration Policies To Control Soil-Transmitted Helminths: A Mathematical Modeling Study Of Ghana, Mugdha Thakur Oct 2019

Evaluation Of Age- And Risk-Based Mass Drug Administration Policies To Control Soil-Transmitted Helminths: A Mathematical Modeling Study Of Ghana, Mugdha Thakur

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Transient Dynamics Of Infection Transmission In An Intensive Care Unit, Christopher Short, Matthew S. Mietchen, Eric T. Lofgren Oct 2019

Transient Dynamics Of Infection Transmission In An Intensive Care Unit, Christopher Short, Matthew S. Mietchen, Eric T. Lofgren

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Characterizing The Permanence And Stationary Distribution For A Family Of Malaria Stochastic Models, Divine Wanduku May 2019

Characterizing The Permanence And Stationary Distribution For A Family Of Malaria Stochastic Models, Divine Wanduku

Biology and Medicine Through Mathematics Conference

No abstract provided.


A Mathematical Model Of The Inflammatory Response To Pathogen Challenge, Lester Caudill, Fiona Lynch Oct 2018

A Mathematical Model Of The Inflammatory Response To Pathogen Challenge, Lester Caudill, Fiona Lynch

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Mathematical Modeling And Simulation With Deep Learning Methods Of Cancer Growth For Patient-Specific Therapy, Vishal Kobla, Joshua P. Smith, Pranav Unni, Padmanabhan Seshaiyer Oct 2018

Mathematical Modeling And Simulation With Deep Learning Methods Of Cancer Growth For Patient-Specific Therapy, Vishal Kobla, Joshua P. Smith, Pranav Unni, Padmanabhan Seshaiyer

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.