Physical Sciences and Mathematics Commons^™

Structural Studies On A Mitochondrial Glyoxalase Ii, Gishanthi P. K. Marasinghe, Ian M. Sander, Brian Bennett, Gopal R. Periyannan, Ke-Wu Yang, Christopher A. Makaroff, Michael W. Crowder

Physics Faculty Research and Publications

Glyoxalase 2 is a β-lactamase fold-containing enzyme that appears to be involved with cellular chemical detoxification. Although the cytoplasmic isozyme has been characterized from several organisms, essentially nothing is known about the mitochondrial proteins. As a first step in understanding the structure and function of mitochondrial glyoxalase 2 enzymes, a mitochondrial isozyme (GLX2-5) from Arabidopsis thaliana was cloned, overexpressed, purified, and characterized using metal analyses, EPR and ¹H NMR spectroscopies, and x-ray crystallography. The recombinant enzyme was shown to bind 1.04 ± 0.15 eq of iron and 1.31 ± 0.05 eq of Zn(II) and to exhibit k_cat and …

Estimation Of Iron Solubility From Observations And A Global Aerosol Model, Chao Luo, N. M. Mahowald, N. Meskhidze, Y. Chen, R. L. Siefert, A. R. Baker, Anne M. Johansen

All Faculty Scholarship for the College of the Sciences

Mineral aerosol deposition is the dominant source of iron to the open ocean. Soil iron is typically insoluble and understanding the atmospheric processes that convert insoluble iron to the more soluble forms observed over the oceans is crucial. In this paper, we model several proposed processes for the conversion of Fe(III) to Fe(II), and compare with cruise observations. The comparisons show that the model results in similar averaged magnitudes of iron solubility as measured during 8 cruises in 2001–2003. Comparisons show that results of cases including cloud, SO₂ and hematite processing are better than the other approaches used using …

Intrinsic Conformational Preferences Of Substituted Cyclohexanes And Tetrahydropyrans Evaluated At The Ccsd(T) Complete Basis Set Limit: Implications For The Anomeric Effect, Abby Jones Weldon, Trisha L. Vickrey, Gregory S. Tschumper

Chemistry Faculty Research & Creative Works

A series of MP2 and CCSD(T) computations have been carried out with correlation consistent basis sets as large as aug-cc-pV5Z to determine the intrinsic equatorial-axial conformational preference of CH 3-, F-, OCH 3-, and OH-substituted cyclohexane and tetrahydropyran rings. The high-accuracy relative electronic energies reported here shed new light on the intrinsic energetics of these cyclic prototypes for the anomeric effect. At the CCSD(T) complete basis set (CBS) limit, the energy of the equatorial conformation relative to the axial position (ΔE CCSD(T)CBC) is -0.75, -0.20, -0.21, and -0.56 kcal mol -1 in methyl-, fluoro-, methoxy-, and hydroxy cyclohexane, respectively, while …

Empirical Likelihood Inference For The Area Under The Roc Curve, Gengsheng Qin, Xiao-Hua Zhou

UW Biostatistics Working Paper Series

For a continuous-scale diagnostic test, the most commonly used summary index of the receiver operating characteristic (ROC) curve is the area under the curve (AUC) that measures the accuracy of the diagnostic test. In this paper we propose an empirical likelihood approach for the inference of AUC. We first define an empirical likelihood ratio for AUC and show that its limiting distribution is a scaled chi-square distribution. We then obtain an empirical likelihood based confidence interval for AUC using the scaled chi-square distribution. This empirical likelihood inference for AUC can be extended to stratified samples and the resulting limiting distribution …

Interval Estimation For The Ratio And Difference Of Two Lognormal Means, Yea-Hung Chen, Xiao-Hua Zhou

UW Biostatistics Working Paper Series

Health research often gives rise to data that follow lognormal distributions. In two sample situations, researchers are likely to be interested in estimating the difference or ratio of the population means. Several methods have been proposed for providing confidence intervals for these parameters. However, it is not clear which techniques are most appropriate, or how their performance might vary. Additionally, methods for the difference of means have not been adequately explored. We discuss in the present article five methods of analysis. These include two methods based on the log-likelihood ratio statistic and a generalized pivotal approach. Additionally, we provide and …

Inferences In Censored Cost Regression Models With Empirical Likelihood, Xiao-Hua Zhou, Gengsheng Qin, Huazhen Lin, Gang Li

UW Biostatistics Working Paper Series

In many studies of health economics, we are interested in the expected total cost over a certain period for a patient with given characteristics. Problems can arise if cost estimation models do not account for distributional aspects of costs. Two such problems are 1) the skewed nature of the data and 2) censored observations. In this paper we propose an empirical likelihood (EL) method for constructing a confidence region for the vector of regression parameters and a confidence interval for the expected total cost of a patient with the given covariates. We show that this new method has good theoretical …

Confidence Intervals For Predictive Values Using Data From A Case Control Study, Nathaniel David Mercaldo, Xiao-Hua Zhou, Kit F. Lau

UW Biostatistics Working Paper Series

The accuracy of a binary-scale diagnostic test can be represented by sensitivity (Se), specificity (Sp) and positive and negative predictive values (PPV and NPV). Although Se and Sp measure the intrinsic accuracy of a diagnostic test that does not depend on the prevalence rate, they do not provide information on the diagnostic accuracy of a particular patient. To obtain this information we need to use PPV and NPV. Since PPV and NPV are functions of both the intrinsic accuracy and the prevalence of the disease, constructing confidence intervals for PPV and NPV for a particular patient in a population with …

College Of Engineering Senior Design Competition Fall 2005, University Of Nevada, Las Vegas

Fred and Harriet Cox Senior Design Competition Projects

Part of every UNLV engineering student’s academic experience, the senior design project stimulates engineering innovation and entrepreneurship. Each student in their senior year chooses, plans, designs and prototypes a product in this required element of the curriculum. A capstone to the student’s educational career, the senior design project encourages the student to use everything learned in the engineering program to create a practical, real world solution to an engineering challenge.

The senior design competition helps to focus the senior students in increasing the quality and potential for commercial application for their design projects. Judges from local industry evaluate the projects …

Self Consistent Bathymetric Mapping Using Sub-Maps: Survey Results From The Tag Hydrothermal Structure, C. Roman, R. Reves-Sohn, H. Singh, S. Humphris

Christopher N. Roman

The spatial resolution of microbathymetry maps created using robotic vehicles such as ROVs, AUVs and manned submersibles in the deep ocean is currently limited by the accuracy of the vehicle navigation data. Errors in the vehicle position estimate commonly exceed the ranging errors of the acoustic mapping sensor itself, which creates inconsistency in the map making process and produces artifacts that lower resolution and distort map integrity. We present a methodology for producing self-consistent maps and improving vehicle position estimation by exploiting accurate local navigation and utilizing terrain relative measurements. The complete map is broken down into individual "sub-maps'', which …

Model Checking For Roc Regression Analysis, Tianxi Cai, Yingye Zheng

Harvard University Biostatistics Working Paper Series

The Receiver Operating Characteristic (ROC) curve is a prominent tool for characterizing the accuracy of continuous diagnostic test. To account for factors that might invluence the test accuracy, various ROC regression methods have been proposed. However, as in any regression analysis, when the assumed models do not fit the data well, these methods may render invalid and misleading results. To date practical model checking techniques suitable for validating existing ROC regression models are not yet available. In this paper, we develop cumulative residual based procedures to graphically and numerically assess the goodness-of-fit for some commonly used ROC regression models, and …

Access Policy Sheet For Access Control In Fine-Grained Xml, Jing Wu, Yi Mu, Jennifer Seberry, Chun Ruan

Faculty of Informatics - Papers (Archive)

We propose an access control scheme for developing authorization rules for XML documents, allowing flexible data granularity and authorization propagation. To simplify the complex access control policies in XML, we introduce a new tool: Authorization Policy Sheet (APS). Complex access control rules can be easily described in an APS. The administrator of a system can easily manage the access control of the system. With aid of Data Type Definitions(DTD), the policies given in an APS can be converted into a standard XML code that can be implemented in a normal XML environment.

Living With Trees – Perspectives From The Suburbs, Lesley M. Head, Pat Muir

Faculty of Science - Papers (Archive)

A study of suburban backyards and backyarders in Sydney and Wollongong revealed evidence of attitudes and behaviours in relation to trees. Attitudes are characterised under themes that indicate conditions of tolerance and belonging. They include attachment/risk, order/freedom and nativeness/alienness. While love is common, high levels of suspicion and intolerance towards trees in the suburban context are more common. Our findings confirm and throw further light on previous work indicating that many Australians have very partitioned views of the world in relationto where humans and nonhuman lifeforms belong. This partitioning must be understood in conceptual as well as spatial terms.

Industrial Technology Education Teachers Perceptions Of National Standards For Technological Literacy In The State Of Arizona, Allan R. Mcrae

Theses and Dissertations

Today, it is becoming increasingly clear that there is a growing interest, concern, and need for technological literacy. To this end, the International Technology Education Association (ITEA) through the Technology for All Americans Project, has developed and promulgated the Standards for Technological Literacy: Content for the Study of Technology. This effort is part of the ongoing initiative to develop technology standards on a national level, and to focus on what every student in grades K-12 should know and be able to do in order to achieve technological literacy (ITEA, 2000). The purpose of this study was to investigate the perceived …

Fluid And Kinetic Structure Of Magnetic Merging In The Swarthmore Spheromak Experiment, W. H. Matthaeus, C. D. Cothran, Matthew Joseph Landreman , '03, Michael R. Brown

Physics & Astronomy Faculty Works

Measurement of the in-plane Lorentz force and the out-of-plane magnetic field associated with the Hall electric field near the reconnection zone in the Swarthmore Spheromak Experiment (SSX) confirms expectations, based on simulation, theory and spacecraft data, that the quadrupolar out-of-plane magnetic field is a signature of collisionless effects in magnetic reconnection with a weak guide field.

Red Rock Desert Learning Center Core Group Meeting: December 6, 2005, Red Rock Desert Learning Center

Reports (RRLC)

1. Introductions & Announcements (5 min.)
2. Approval of Minutes from October 18, 2005 Meeting (5 min.)
3. Update on Project Schedule – Michael Reiland (10 min.)
   A. Utilities
   B. Water Line
   C. Parking
   D. Operator
4. Update on Design Development – Michael Reiland (10 min.)
5. Cultural Treatment Plan – Michael Reiland (10 min.)
6. Environmental Assessment Update – Otak Inc. (10 min.)
7. Curriculum Update – Jeanne Klockow (10 min.)
8. Standing Reports (10 min.)
   A. BLM Capital Improvements – Michael Reiland
   B. Community Outreach – LaNelda Rolley
9. Committee Reports (5 min.)
   A. Building Committee
   B. Design Oversight
   C. Educational Programs
   D. Fund-raising and Partnerships
   E. …

Multiple Channel Laser Beam Combination And Phasing Using Stimulated Brillouin Scattering In Optical Fibers, Brent W. Grime

Theses and Dissertations

Brightness scaling lasers using stimulated Brillouin scattering (SBS) in optical fibers is explored. A multiple-channel amplifier approach is used to increase the total power of a laser system while avoiding a significant burden on a single channel. The work explores two approaches utilizing both SBS beam cleanup and SBS piston error conjugation. A unique beam combiner that takes advantage of the SBS beam cleanup properties of a long, gradient-index multimode fiber was designed and tested. The beam combiner was developed to combine multiple-channel laser beams simultaneously with high input and output coupling efficiency. The design for the SBS beam combiner …

Preliminary Survey Of Rattlesnake Brook

Watershed Access Lab Projects

Rattlesnake Brook is located in Assonet, MA, passing under Rte 24 near exit #9 and under South Main Street. The stream was accessed at three sites: NSTAR (just upstream from the South Main St. culvert), Rapoza (downstream at 114 South Main St.) and Narrows Road (just upstream from the Narrows Rd culvert prior to the stream’s confluence with the Assonet River). One major change in land use is the addition of the Stop & Shop distribution center on South Main St. behind the Rapoza site.

Initial data for temperature and DO indicate that dissolved oxygen is high at the first …

A Water Quality Study Of Germany Brook, A Tributary Of The Neponset River

Watershed Access Lab Projects

Germany Brook is a first-order stream that originates in Westwood and travels two miles emptying into Ellis Pond in Norwood. Earlier sampling conducted by volunteers affiliated with the Neponset River Watershed Association on the lower reaches of the stream had indicated marginal water quality characterized by high nutrient and bacterial levels. In order to assess the potential impact of surrounding land uses on water quality in the stream, the benthic macroinvertebrate community was sampled at two stations during October, 2005.

It was hypothesized that the upstream station should have better water quality than its downstream counterpart as the upper reaches …

A Comparison Study: Fall Book And A Natural Spring; Focus: Water Chemistry

Watershed Access Lab Projects

The purpose of the study was to compare two fresh water resources in the Freetown Lakeville area. One site found was a natural spring located in Lakeville near Morgan Reserves off Long Pont Road. The Spring is located in the woods and in a remote location. The water from the spring enters into Little Quittacas Pond, a reservoir for New Bedford drinking water. The other freshwater site was a brook called Fall Brook in Freetown located off Gurney Road. The brook is located near Still Water Fastener Factory and flows under Gurney Road.

The focus of the study was on …

Macro Invertebrates Of Kirby Brook

Watershed Access Lab Projects

The purpose of our project was to compare the relative abundance of Macroinvertebrates at two sites on Kirby Brook in Westport MA. One site was in the woods behind our high school approximately 1/4 of a mile along an overgrown trail. These woods are frequented in the winter for hunting purposes. At the time of the study, the water was stagnant due to lack of rain. The second site was across from a farm on Drift Rd. The water was low but flowing.

At both sites, Oligochaetes made up the majority of Macroinvertebrates (231 at site 1, 71 at site …

The Taunton River's Last Major Tributary: Chemical Analysis Of A Freshwater Dam System In The Upper Assonet River

Watershed Access Lab Projects

No abstract provided.

Comparative Study Of Leonard Washburn Brook And Poquoy Brook

Watershed Access Lab Projects

Leonard Washburn Brook is a tributary of Poquoy Brook. It is located in Lakeville, MA and was accessed on Cross Street. We considered this our pristine river environment. Poquoy Brook, also of Lakeville, MA was accessed on Taunton Street. We considered this our river with many land uses as it passes through both a cranberry bog and a golf course.

Initial data for temperature and DO indicate that dissolved oxygen is higher at the Leonard Washburn than Poquoy Brook. Poquoy follows a normal diurnal curve while Leonard Washburn fluctuates with temperature due to lack of vegetation in the water column. …

A Comparison Of Divergent Sites On The Farm River: Wetlands Vs. Industry

Watershed Access Lab Projects

The Fore River Watershed initiates in the Blue Hills of Milton, Massachusetts. The Farm River, which flows through Braintree, Massachusetts, is one of the tributaries. It is a first order river that contributes to Great Pond, the major water supply for Braintree, Randolph and Avon. As the Farm River proceeds beyond Great Pond, it passes within thirty feet of an industrial park and shopping mall for approximately 1km. It also passes under a heavily traveled road, Granite Street. The amount of imperviousness in the area is considerable

The purpose of this study was to determine if a river flows through …

A River With History: Evaluating The Aberjona River

Watershed Access Lab Projects

No abstract provided.

The Effect Of Autumn Leaf Drop On Water Quality At Turner's Pond Outlet

Watershed Access Lab Projects

The purpose of this study was to determine the impact that the autumn leaf drop associated with the changing seasons has on water quality. Students in the senior elective, Botany, participated in this study of the main outlet of Turner’s Pond in Dartmouth, Massachusetts. The students designated two test sites downstream from the dam that holds back Turner’s Pond. Testing was done October 6 and 7, 2005 and October 27 and 28, 2005. The first dates were prior to the leaf drop and the second dates occurred after leaf drop had started but not yet been completed. The macroinvertebrate sampling …

The Runnins Report

Watershed Access Lab Projects

For the past 4 years, students in AP Biology have performed summer Ecology research studies at Burr’s Pond in Seekonk. One goal of the summer research has been to provide the students with a relevant, meaningful inquiry-based learning experience. At the start of the school year, the students measure the dissolved oxygen as part of the required AP Laboratory Exercise 12. A second goal of the summer research has been to sustain an annual evaluation of the dissolved oxygen as well as the diversity and distribution of organisms in and around the pond. Unfortunately, the data is not very accurate …

Service Discovery In Wireless Ad-Hoc Control Networks, Shengrong Bu, F. Naghdy

Faculty of Informatics - Papers (Archive)

A new concept in distributed control systems called Wireless Ad-hoc Control Networks (WACNets) is developed. WACNets is formed by a collection of nodes with the ability to sense, actuate and control. The network does not have a fixed structure, but evolves and self organises itself according to the control requirements of the system. The service discovery developed for WACNets is reported. A review of the existing Service Discovery Protocol (SDPs) including Jini, Salutation, Universal Plug and Play (UPnP), and Bluetooth technology is carried out. An overview of WACNets is provided. The service discovery protocol developed for WACNets is introduced and …

Making Sense Of Nanocrystal Lattice Fringes, Phil Fraundorf, Wentao Qin, Peter Moeck, Eric Mandell

Physics Faculty Works

The orientation dependence of thin-crystal lattice fringes can be gracefully quantified using fringe-visibility maps, a direct-space analog of Kikuchi maps [Nishikawa and Kikuchi, Nature (London) 121, 1019 (1928)]. As in navigation of reciprocal space with the aid of Kikuchi lines, fringe-visibility maps facilitate acquisition of crystallographic information from lattice images. In particular, these maps can help researchers to determine the three-dimensional lattice of individual nanocrystals, to “fringe-fingerprint” collections of randomly oriented particles, and to measure local specimen thickness with only a modest tilt. Since the number of fringes in an image increases with maximum spatial-frequency squared, these strategies (with help …

On The Use Of Non-Euclidean Isotropy In Geostatistics, Frank C. Curriero

Johns Hopkins University, Dept. of Biostatistics Working Papers

This paper investigates the use of non-Euclidean distances to characterize isotropic spatial dependence for geostatistical related applications. A simple example is provided to demonstrate there are no guarantees that existing covariogram and variogram functions remain valid (i.e.\ positive definite or conditionally negative definite) when used with a non-Euclidean distance measure. Furthermore, satisfying the conditions of a metric is not sufficient to ensure the distance measure can be used with existing functions. Current literature is not clear on these topics. There are certain distance measures that when used with existing covariogram and variogram functions remain valid, an issue that is explored. …

Cornhusker Army Ammunition Plant Nebraska, Bryant Burnett, Karla Asberry

United States Environmental Protection Agency: Publications

The 19-square mile Cornhusker Army Ammunition Plant is a former U.S. Army Armament, Munitions, and Chemical Command facility. On standby status since 1973, the operation leases land for agriculture, grazing, and wildlife management activities. The plant was built in 1942 to produce munitions and provide support functions during World War II. It has been in and out of production over the years. The plant consists of five main components: five major production areas where munitions were loaded, assembled, and packed; a fertilizer manufacturer; two major storage facilities; a sanitary landfill; and a burning ground where materials contaminated with explosives were …