Physical Sciences and Mathematics Commons^™

Optimization Of Electrode Alignment For Electrochemical Detection In Capillary Electrophoresis Using A Scanning Electrochemical Microscope, David Roach, Stephanie Hooper, Mark Anderson

Mark R. Anderson

Electrochemical detection in capillary electrophoresis requires decoupling the voltage applied to the working electrode from the separation voltage applied across the capillary. End-capillary electrochemical detection achieves this by placing the electrode just outside the ground end of the separation capillary. Obtaining adequate signal-to-noise in this arrangement requires using small inner diameter capillaries. Decreasing the inner diameter of the separation capillary, however, increases the difficulty of aligning the microelectrode with the open end of the capillary. Using scanning electrochemical microscopy (SECM), the position of the capillary opening is determined while electroactive material is continuously emerging from the end of the capillary. …

Scaling Laws For Rotating Rayleigh-Bénard Convection, Janet Scheel, M. Cross

Janet D. Scheel

Numerical simulations of large aspect ratio, three-dimensional rotating Rayleigh-Bénard convection for no-slip boundary conditions have been performed in both cylinders and periodic boxes. We have focused near the threshold for the supercritical bifurcation from the conducting state to a convecting state exhibiting domain chaos. A detailed analysis of these simulations has been carried out and is compared with experimental results, as well as predictions from multiple scale perturbation theory. We find that the time scaling law agrees with the theoretical prediction, which is in contradiction to experimental results. We also have looked at the scaling of defect lengths and defect …

A Pair Of General Series-Transformation Formulas, Tian-Xiao He, Leetsch Hsu, Peter Shiue

Tian-Xiao He

No abstract provided.

Numb3rs: The Intersection Between Mathematics And Hollywood Is Not Empty, Ron Buckmire

Ron Buckmire

No abstract provided.

Defect Structure Of Sb2−Xmnxte3 Single Crystals., Jaromír Horák, Petr LošŤÁK, Čestmír Drašar, Jeffrey Dyck, Zengzua Zhou, Cterid Uher

Jeffrey Dyck

Incorporation of the transition metal elements in the tetradymite structure of Sb2Te3 has a strong influence on electronic properties. Recent studies have indicated that Mn substitutes on the Sb sublattice increases the carrier concentration of holes. However, the doping efficiency of Mn appears rather low in comparison to what it should be based on the measurements of magnetization, structural analysis, and transport properties. In this paper we address this issue by making detailed studies of the Hall effect and electrical resistivity and we explain the results with the aid of a model that takes into account interactions of the Mn …

Unraveling The Mechanism Of A Potent Transcriptional Activator, Brian Brennan, Zhen Lu, Steven Rowe, Sarah Davis, Renee Metzler, Johnathan Nau, Chinmay Majmudar, Anna Mapp, Aseem Ansari

Brian B. Brennan

Despite their enormous potential as novel research tools and therapeutic agents, artificial transcription factors (ATFs) that up-regulate transcription robustly in vivo remain elusive. In investigating an ATF that does function exceptionally well in vivo, we uncovered an unexpected relationship between transcription function and a binding interaction between the activation domain and an adjacent region of the DNA binding domain. Disruption of this interaction leads to complete loss of function in vivo, even though the activation domain is still able to bind to its target in the transcriptional machinery. We propose that this interaction parallels those between natural activation domains and …

Decoherence As A Measure Of Entanglement, Padmanabhan Aravind, Denis Tolkunov, Vladimir Privman

Padmanabhan K. Aravind

For a solvable pure-decoherence model, we confirm by an explicit model calculation that the decay of entanglement of two state systems (two quibits) is approximately governed by the product of the suppression factors describing decoherence of the subsystems, provided that they are subject to uncorrelated sources of quantum noise. This demonstrates an important physical property that separated open quantum systems can evolve quantum mechanically on time scales larger than the times for which they remain entangled.

The Air Is Always Cleaner On The Other Side: Race, Space, And Ambient Air Toxics Exposures In California, Manuel Pastor, Rachel Morello-Frosch, James Sadd

James Sadd

Environmental justice advocates have recently focused attention on cumulative exposure in minority neighborhoods due to multiple sources of pollution. This article uses U.S. EPA’s National Air Toxics Assessment (NATA) for 1996 to examine environmental inequality in California, a state that has been a recent innovator in environmental justice policy. We first estimate potential lifetime cancer risks from mobile and stationary sources. We then consider the distribution of these risks using both simple comparisons and a multivariate model in which we control for income, land use, and other explanatory factors, as well as spatial correlation. We find large racial disparities in …

Transport Coefficients Of Titanium-Doped Sb2te3 Single Crystals., Č. Drašar, M. Steinhart, P. Lošťák, H.-K. Shin, Jeffrey Dyck, C. Uher

Jeffrey Dyck

Titanium-doped single crystals (cTi=0–2×1020atomscm−3) were prepared from the elements Sb, Ti, and Te of 5N purity by a modified Bridgman method. The obtained crystals were characterized by measurements of the temperature dependence of the electrical resistivity, Hall coefficient, Seebeck coefficient and thermal conductivity in the temperature range of 3–300K. It was observed that with an increasing Ti content in the samples the electrical resistivity, the Hall coefficient and the Seebeck coefficient increase. This means that the incorporation of Ti atoms into the Sb2Te3 crystal structure results in a decrease in the concentration of holes in the doped crystals. For the …

Low-Temperature Ferromagnetic Properties Of The Diluted Magnetic Semiconductor Sb2-X Crx Te3 ., Jeffrey Dyck, Č. Drašar, P. LošŤÁK, C. Uher

Jeffrey Dyck

We report on magnetic and electrical transport properties of Sb2-x Crx Te3 single crystals with 0⩽x⩽0.095 over temperatures from 2 K to 300 K . A ferromagnetic state develops in these crystals at low temperatures with Curie temperatures that are proportional to x (for x>0.014 ), attaining a maximum value of 20 K for x=0.095 . Hysteresis below TC for the applied field parallel to the c axis is observed in both magnetization and Hall-effect measurements. Magnetic as well as transport data indicate that Cr takes the 3+ (3 d3 ) valence state, substituting for antimony in the host …

Thermal And Conductivity Studies Of Chitosan Acetate-Based Polymer Electrolytes, Zurina Osman

Zurina Osman

Thermogravimetric Analysis (TGA) and Differential Scanning Calorimetry (DSC) have been employed to study the thermal stability of the chitosan acetate-based polymer electrolyte films. The glass transition temperature, T-g measurements confirm the conductivity enhancement effect by adding the plasticizer and salt in the chitosan acetate films

Constraint Programming, John Hooker

John Hooker

No abstract provided.

Applications Of Mickens Finite Differences To Several Related Boundary Value Problems, Ron Buckmire

Ron Buckmire

No abstract provided.

Effects Of Electron Irradiation On The Ferroelectric Properties Of Langmuir-Blodgett Copolymer Films, Christina Othon, Fred Bateman, Stephen Ducharme

Christina M Othon

The effect of irradiation on the ferroelectric properties of Langmuir-Blodgett films of the copolymer poly(vinylidene fluoride-trifluoroethylene) was investigated using 1‐MeV electrons for doses from 0.16 to 1.10 MGy, where 1 Gray (Gy) = 100 rad. Irradiation causes a systematic decrease in the phase-transition temperature, crystallinity, and spontaneous polarization of the films. The crystallinity and spontaneous polarization of the films decreased by amounts proportional to the dose, both tending toward zero near a dose of 1.30 MGy. The ferroelectric-paraelectric phase-transition temperature, however, was only reduced by about 12%, indicating that the primary effect of irradiation was to convert a crystalline ferroelectric …

Stereochemical Promiscuity In Artificial Transcriptional Activators, Brian Brennan, Sara Buhrlage, Aaron Minter, Anna Mapp

Brian B. Brennan

Small molecule replacements of transcriptional activation domains are highly desirable targets due to their utility as mechanistic tools and their long-term therapeutic potential for a variety of human diseases. Here, we examine the ability of amphipathic isoxazolidines differing only in the placement of constituent side chains to function as transcriptional activation domains. The results reveal that precise positioning of functional groups within a conformationally constrained small molecule scaffold is not required for transcription function; rather, the balance of polarity and hydrophobicity within the scaffold is the more important determinant of transcription function. This suggests that a number of different organic …

Amyloid Fibril Formation By Bovine Milk Kappa-Casein And Its Inhibition By The Molecular Chaperones Alpha-S And Beta-Casein, Mark Wilson, David Thorn, Agata Rekas, S. L Gras, Christopher Dobson, Sarah Meehan, Cait Macphee, M Sunde

Mark R Wilson

No abstract provided.

Heat Shock Protein 70 Inhibits Alpha-Synuclein Fibril Formation Via Preferential Binding To Prefibrillar Species, Mark Wilson, M. M. Dedmon, J. Christodoulou, Christopher Dobson

Mark R Wilson

No abstract provided.

Lymphotoxin-Beta Receptor-Dependent Genes In Lymph Node And Follicular Dendritic Cell Transcriptomes, Mark Wilson, C. Huber, C. Thielen, Y. Fu, E. Heinen, A Aguzzi, G Miele

Mark R Wilson

No abstract provided.

Approximate Solutions For Magmon Propagation From A Reservoir, Tim Marchant

Tim Marchant

A 1D partial differential equation (pde) describing the flow of magma in the Earth's mantle is considered, this equation allowing for compaction and distension of the surrounding matrix due to the magma. The equation has periodic travelling wave solutions, one limit of which is a solitary wave, called a magmon. Modulation equations for the magma equation are derived and are found to be either hyperbolic or of mixed hyperbolic/elliptic type, depending on the specific values of the wave number, mean height and amplitude of the underlying modulated wave. The periodic wave train is stable in the hyperbolic case and unstable …

Overview Of Radiometric Ages In Three Allochthonous Belts Of Northern Venezuela: Old Ones, New Ones, And Their Impact On Regional Geology, V Sisson, H Lallemant, M Ostos, Ann Blythe, L Snee, P Copeland, J Wright, R Donelick, L Guth

Ann Blythe

No abstract provided.

The Acute Phase Protein Haptoglobin Is A Mammalian Extracellular Chaperone With An Action Similar To Clusterin, Justin Yerbury, Mark S Rybchyn, Simon B Easterbrook-Smith, C. Henriques, Mark Wilson

Mark R Wilson

Haptoglobin (Hp) is an acidic glycoprotein present in most body fluids of humans and other mammals. Although the functions of Hp are not yet fully understood, the available evidence indicates that it is likely to play an important role in suppressing inflammatory responses. Some earlier work suggested that Hp might be a newly identified member of a small group of extracellular chaperones found at significant levels in human body fluids. Previously, the only well-characterized member of this group was clusterin, which shares functional similarities with the small heat-shock proteins. We report here that Hp specifically inhibited the precipitation of a …

Exploring The Persistence Of Sorted Bedforms On The Inner-Shelf Of Wrightsville Beach, North Carolina, Benjamin Gutierez, George Voulgaris, Robert Thieler

George Voulgaris

Geological studies offshore of Wrightsville Beach, North Carolina reveal subtle large-scale regions of coarse sand with gravel and shell hash (widths between 100 and 200 m and negative relief of ∼1 m) that trend obliquely to the coast. It was previously suggested that these regions serve as conduits for sand exchange between the shoreface and inner shelf during storm-associated downwelling. Consequently they were classified as rippled scour depressions. More recently, the role of alongshore flows and self-organization as a result of inhibited settling of fine sand has been discussed. In this study, 45 days of near-bed current measurements were analyzed …

Effect Of Channel Bifurcation On Residual Estuarine Circulation: Winyah Bay, South Carolina, Yong Kim, George Voulgaris

George Voulgaris

The residual circulation pattern of Winyah Bay, the fourth largest estuary on the eastern coast of the US, is examined using stationary and shipborne current measurements during periods of low freshwater discharge. The estuary has a complex morphology with a single channel and narrow banks at the river entrance and the bay mouth, and a bifurcated channel system (main and western channels, respectively) in the middle part that appears to affect the residual circulation. Overall, the upper (single channel morphology) and middle (dual-channel morphology) parts of the estuary exhibit a baroclinic residual circulation. The presence of bifurcated channels in the …

A Solvent-Free Baeyer–Villiger Lactonization For The Undergraduate Organic Laboratory: Synthesis Of Γ-T-Butyl-Ε-Caprolactone, John Esteb, James Hohman, Diana Schlamadinger, Anne Wilson

John Esteb

We present an experiment involving the Baeyer–Villiger oxidation reactionfor a first-year organic chemistry class. The Baeyer–Villiger reactionprovides an efficient method to convert ketones to esters or lactones. Most organictextbooks cover the Baeyer–Villiger reaction but owing to a lack of suitableexperiments, students seldom get to explore the reaction in the undergraduateteaching laboratory. In this experiment, m-chloroperoxybenzoic acid(m-CPBA) and4-tert-butylcyclohexanone are mixed together for 30 minutes under solvent-freeconditions to produce γ-t-butyl-ε-caprolactone in 95%yield. The solvent-free nature of this procedure greatly limits the quantityof waste generated by students and keeps costs low by removing the need for solvent.

Note:Link is to the article …

Systematic Studies In Pattern Avoidance, Lara Pudwell, Shalosh Ekhad, Vince Vatter

Lara K. Pudwell

No abstract provided.

Sustainable Development And Natural Governance: The Challenges Ahead, John Dernbach, Dan Tarlock

John C. Dernbach

No abstract provided.

Integrating High-Precision Aftershock Locations And Geodetic Observations To Model Coseismic Deformation Associated With The 1995 Kozani-Grevena Earthquake, Greece, Phillip G. Resor, David Pollard, T J. Wright, G C. Beroza

Phillip G Resor

We integrate high-precision aftershock locations with geodetic inverse modeling to create a more complete kinematic model for the Kozani-Grevena earthquake sequence. Using the double-difference algorithm, we have improved relative hypocentral locations by a factor of ∼7 and thus imaged the details of the fault network associated with the seismic sequence. The interpreted fault network consists of multiple segments including (1) a master normal fault that strikes nearly due west and dips toward the north at 43°, extending from 6 to 15 km depth; (2) an upper segment that connects the top of the seismicity to the observed surface ruptures and …

Inverting For Slip On Three-Dimensional Fault Surfaces Using Angular Dislocations, Phillip G. Resor, David Pollard, Frantz Maerten, Laurent Maerten

Phillip G Resor

The increasing quality of geodetic data (synthetic aperture radar interferometry [INSAR] dense Global Positioning System [GPS] arrays) now available to geophysicists and geologists are not fully exploited in slip-inversion procedures. Most common methods of inversion use rectangular dislocation segments to model fault ruptures and therefore oversimplify fault geometries. These geometric simplifications can lead to inconsistencies when inverting for slip on earthquake faults, and they preclude a more complete understanding of the role of fault geometry in the earthquake process. We have developed a new three-dimensional slip-inversion method based on the analytical solution for an angular dislocation in a linear-elastic, homogeneous, …

Hartford Basin Cross Section – Southington To Portland, Ct, Phillip G. Resor, J Z. Deboer

Phillip G Resor

No abstract provided.

Laramie Peak Shear System, Central Laramie Mountains, Wyoming, Usa: Regeneration Of The Archean Wyoming Province During Palaeoproterozoic Accretion, Phillip G. Resor, Arthur W. Snoke

Phillip G Resor

The Laramie Peak shear system (LPSS) is a 10 km-thick zone of heterogeneous general shear (non-coaxial) that records significant tectonic regeneration of middle-lower crustal rocks of the Archean Wyoming province. The shear system is related to the 1.78–1.74 Ga Medicine Bow orogeny that involved the collision of an oceanic-arc terrane (Colorado province or Green Mountain block or arc) with the rifted, southern margin of the Wyoming province. The style and character of deformation associated with the LPSS is distinctive: a strong, penetrative (mylonitic) foliation commonly containing a moderately steep, SW-plunging elongation lineation. In mylonitic quartzo-feldspathic gneisses of the Fletcher Park …