Physical Sciences and Mathematics Commons^™

Embedding Information Literacy Practices In An Upper Division Chemistry Lab Class At A University In The United States Of America, Christopher Randles, Matilynn Lamm, Katy A. Miller

Faculty Scholarship and Creative Works

This poster discusses the implementation of information literacy into an upper division inorganic chemistry lab and the strategies employed to develop students’ information literacy in the laboratory course.

Ex-Vivo Hippocampus Segmentation Using Diffusion-Weighted Mri, Haoteng Tang, Siyuan Dai, Eric M. Zou, Guodong Liu, Ryan Ahearn, Ryan Krafty, Michel Modo, Liang Zhan

Computer Science Faculty Publications and Presentations

The hippocampus is a crucial brain structure involved in memory formation, spatial navigation, emotional regulation, and learning. An accurate MRI image segmentation of the human hippocampus plays an important role in multiple neuro-imaging research and clinical practice, such as diagnosing neurological diseases and guiding surgical interventions. While most hippocampus segmentation studies focus on using T1-weighted or T2-weighted MRI scans, we explore the use of diffusion-weighted MRI (dMRI), which offers unique insights into the microstructural properties of the hippocampus. Particularly, we utilize various anisotropy measures derived from diffusion MRI (dMRI), including fractional anisotropy, mean diffusivity, axial diffusivity, and radial diffusivity, for …

Artificial Intelligence Usage And Data Privacy Discoveries Within Mhealth, Jennifer Schulte

Research & Publications

Advancements in artificial intelligence continue to impact nearly every aspect of human life by providing integration options that aim to supplement or improve current processes. One industry that continues to benefit from artificial intelligence integration is healthcare. For years now, elements of artificial intelligence have been used to assist in clinical decision making, helping to identify potential health risks at earlier stages, and supplementing precision medicine. An area of healthcare that specifically looks at wearable devices, sensors, phone applications, and other such devices is mobile health (mHealth). These devices are used to aid in health data collection and delivery. This …

Doubly Charged Dimers And Trimers Of Heavy Noble Gases, Gabriel Schöpfer, Stefan Bergmeister, Milan Ončák, Ianessa Stromberg, Masoomeh Mahmoodi-Darian, Paul Scheier, Olof Echt, Elisabeth Gruber

Faculty Publications

Many doubly charged heteronuclear dimers are metastable or even thermodynamically stable with respect to charge separation. Homonuclear dicationic dimers, however, are more difficult to form. He₂²⁺ was the first noble gas dimer predicted to be metastable and, decades later, observed. Ne₂²⁺ is the only other dicationic noble gas dimer that has been detected so far. Here, we present a novel approach to form fragile dicationic species, by post-ionization of singly charged ions that are embedded in helium nanodroplets (HNDs). Bare ions are then extracted by colliding the HNDs with helium gas. We detect homonuclear doubly charged …

Estimating Polarization Purity With Noise, Alex Kostinski, Dan Kestner, Jothiram Vivekanandan

Michigan Tech Publications, Part 2

We formulate a problem of estimating and monitoring mismatch (unwanted departure from orthogonality) of two ostensibly orthogonal polarization channels in a fully polarimetric general device such as a polarimetric weather radar. A statistical approach is proposed by using thermal noise or, more generally, a 'polarimetric noise' class of sources. The suitable noise class of distributions is shown to be rooted in the complex multivariate Gaussian probability density function (pdf), the latter possessing a uniform pdf on the Poincare sphere (PS), with a probability measure given by a fractional surface area. To that end, we develop a parameter to estimate polarization …

2024 March 21 - Tennessee Weekly Drought Summary, Tennessee Climate Office, East Tennessee State University

Tennessee Climate Office Weekly Drought Summaries

No abstract provided.

Second Inflection Point Of Supercooled Water Surface Tension Induced By Hydrogen Bonds: A Molecular-Dynamics Study, Fawaz Hrahsheh, Inshad Jum'h, Gerald Wilemski

Physics Faculty Research & Creative Works

Surface Tension Of Supercooled Water Is A Fundamental Property In Various Scientific Processes. In This Study, We Perform Molecular Dynamics Simulations With The TIP4P-2005 Model To Investigate The Surface Tension Of Supercooled Water Down To 220 K. Our Results Show A Second Inflection Point (SIP) In The Surface Tension At Temperature TSIP ≈ 267.5 ± 2.3 K. Using An Extended IAPWS-E Functional Fit For The Water Surface Tension, We Calculate The Surface Excess Internal-Energy And Entropy Terms Of The Excess Helmholtz Free Energy. Similar To Prior Studies [Wang Et Al., Phys. Chem. Chem. Phys. 21, 3360 (2019); Gorfer Et Al., …

Sustainability And Careers In The 21st Century, Phyllis J. Schoen, Amanda Baker

Sustainability Research & Practice Seminar Presentations

Phyllis Schoen and Amanda Baker of the West Chester University Career Center present on "Sustainability and Careers in the 21st Century."

Using Chatgpt To Generate Gendered Language, Shweta Soundararajan, Manuela Nayantara Jeyaraj, Sarah Jane Delany

Conference papers

Gendered language is the use of words that denote an individual's gender. This can be explicit where the gender is evident in the actual word used, e.g. mother, she, man, but it can also be implicit where social roles or behaviours can signal an individual's gender - for example, expectations that women display communal traits (e.g., affectionate, caring, gentle) and men display agentic traits (e.g., assertive, competitive, decisive). The use of gendered language in NLP systems can perpetuate gender stereotypes and bias. This paper proposes an approach to generating gendered language datasets using ChatGPT which will provide data for data-driven …

Will Saf Turbocharge The Corn Ethanol Market?, Richard Perrin, Lilyan Fulginiti, Felipe Miranda De Souza Almeida

Cornhusker Economics

The long-run outlook for the corn ethanol industry is questionable, due to a transition to electric and hybrid vehicles. One source of hope for the long run is the potential demand for producing Sustainable Aviation Fuel (SAF). SAF is a key component in the United States Aviation Climate Action Plan, a path to net-zero greenhouse gas (GHG) emissions in the aviation industry by 2050. Demand for ethanol for SAF offers hope to the ethanol industry, but it depends a great deal on policy decisions that are being made now. Here we sketch out this story.

Based on the information available …

Residential Metals Abatement Program Investigation Summary Report (Non-Residential Parcels – Indoor Dust) - Emerson Elementary School, Environmental Resource Management (Erm)

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Neutrino’S Non-Zero Electric Potential As An Origin Of Gravitation, Domain Structure And Expansion Of The Universe., Polievkt Perov

College of Arts & Sciences Faculty Works

The axial electric potentials of neutrinos as neutral composite structures, while being very small at large distances, do not vanish, and the same can be said about the neutrino “asymmetric dipoles” (paired neutrinos of not the same kind). Depending on the orientation of the “asymmetric dipole”, its far-field electric potential in some direction can be positive or negative, interacting with other “dipoles” at that large distance attractively or repulsively depending on their mutual orientation. The mutual orientation of the dipoles locally (inside a galaxy) might be such that they are aligned and experience the attractive force toward the local center …

A Multi-Omics Investigation Into The Mechanism Of Action Of An Anti-Tubercular Fatty Acid Analog, Isin T. Sakallioglu, Amith S. Maroli, Aline De Lima Leite, Darrell D. Marshall, Boone W. Evans, Denise K. Zinniel, Patrick H. Dussault, Raul G. Barletta, Robert Powers

Patrick Dussault Publications

The mechanism of action (MoA) of a clickable fatty acid analogue 8-(2-Cyclobuten-1-yl)octanoic acid (DA-CB) has been investigated for the first time. Proteomics, metabolomics, and lipidomics were combined with a network analysis to investigate the MoA of DA-CB against Mycobacterium smegmatis (Msm). The metabolomics results showed that DA-CB has a general MoA related to that of ethionamide, a mycolic acid inhibitor that targets enoyl-ACP reductase (InhA), but DA-CB likely inhibits a step downstream from InhA. Our combined multi-omics approach showed that DA-CB appears to disrupt the pathway leading to the biosynthesis of mycolic acids, an essential mycobacterial fatty acid …

Leveraging The Hmbc To Facilitate Metabolite Identification, Fatema Bhinderwala, Thao Vu, Thomas G. Smith, Julian Kosacki, Darrell D. Marshall, Yuhang Xu, Martha D. Morton, Robert Powers

Chemistry Department: Faculty Publications

The accuracy and ease of metabolite assignments from a complex mixture are expected to be facilitated by employing a multi-spectral approach. The 2D ¹H-¹³C HSQC and 2D ¹H-¹H-TOCSY are the experiments commonly used for metabolite assignments. The 2D ¹H-¹³C HSQC-TOCSY and 2D ¹H-¹³C HMBC are routinely used by natural products chemists but have seen minimal usage in metabolomics despite the unique information, the nearly complete ¹H-¹H and ¹H-¹³C and spin systems provided by these experiments that may improve the accuracy and reliability …

Beyond Standard Model: Neutrino-Antineutrino Pairs In Nuclear Reactions Of Beta-Decay And Proton-Neutron Transmutation., Polievkt Perov

College of Arts & Sciences Faculty Works

On examples of different beta-decay reactions, we show that the neutrino-antineutrino pairs should be added as necessary reagents to the equations of the decay reactions where a neutrino or an antineutrino is among the products of the reaction. In our models, quarks and leptons are all made of basic fractional +-e/3 charges. Transfer of basic charges between reagents forms the products of the reaction. We suggest that there is no direct conversion of u-quark to d-quark and visa versa. Each transmutation involves a transfer of basic charges from a neutrino to a quark so the structure of remaining charges in …

Role Of Electronegativity In Environmentally Persistent Free Radicals (Epfrs) Formation On Zno, Syed Monjur Ahmed, Reuben Oumnov, Orhan Kizilkaya, Randall W. Hall, Philip T. Sprunger, Robert L. Cook

Natural Sciences and Mathematics | Faculty Scholarship

Environmentally persistent free radicals (EPFRs), a group of emerging pollutants, have significantly longer lifetimes than typical free radicals. EPFRs form by the adsorption of organic precursors on a transition metal oxide (TMO) surface involving electron charge transfer between the organic and TMO. In this paper, dihalogenated benzenes were incorporated to study the role of electronegativity in the electron transfer process to obtain a fundamental knowledge of EPFR formation mechanism on ZnO. Upon chemisorption on ZnO nanoparticles at 250 °C, electron paramagnetic resonance (EPR) confirms the formation of oxygen adjacent carbon-centered organic free radicals with concentrations between 1016 and 1017 spins/g. …

Asymptotics Of The Rate Function In The Large Deviation Principle For Sums Of Independent Identically Distributed Random Variables, Iosif Pinelis

Michigan Tech Publications, Part 2

Let Λ∗be the rate function in the large deviation principle for the sums X1 + · · · + Xn of independent identically distributed random variables X1, X2, …. It is shown that Λ∗(x) ∼ − ln P(X1 ≥ x) (as x → ∞) if and only if ln P(X1 ≥ x) ∼ L0(x) for some concave function L0. The main ingredient of the proof is the general, explicit expression of a suitable quasi-minimizer in t ≥ 0 of the Bernstein–Chernoff upper bound e−txEetX1 on P(X1 ≥ x), which is amenable to analysis and, at the same time, is close …

Terry Riley's "In C" For Mobile Ensemble, David B. Wetzel, Griffin Moe, George K. Thiruvathukal

Computer Science: Faculty Publications and Other Works

This workshop presents a mobile-friendly Web Audio application for a “technology ensemble play-along” of Terry Riley’s 1964 composition In C. Attendees will join in a reading of In C using available web-enabled devices as musical instruments. We hope to demonstrate an accessible music-technology experience that relies on face-to-face interaction within a shared space. In this all-electronic implementation, no special musical or technical expertise is required.

Accepted for presentation and publication at WAC 2024.

Enhanced Route Navigation Control System For Turtlebot Using Human-Assisted Mobility And 3-D Slam Optimization, Ankit Kumar, Kamred Udham Singh, Pankaj Dadheech, Aditi Sharma, Ahmed I. Alutaibi, Ahed Abugabah, Arwa Mohsen Alawajy

All Works

An autonomous, power-assisted Turtlebot is presented in this paper in order to enhance human mobility. The turtlebot moves from its initial position to its final position at a predetermined speed and acceleration. We propose an intelligent navigation system that relies solely on individual instructions. When there is no individual present, the Turtlebot remains stationary. Turtlebot utilizes a rotating Kinect sensor in order to perceive its path. Various angles were examined in order to demonstrate the effectiveness of the system in experiments conducted on a U-shaped experimental pathway. The Turtlebot was used as an experimental device during these trials. Based on …

Re: Comments For The Butte Priority Soils Operable Unit (Bpsou) Butte Reclamation Evaluation System (Bres) Draft 2023 Bres Field Evaluation Summary Report And Technical Recommendations Proposal (Dated November 15, 2023) And 2023 Corrective Action Plans For Reclaimed Sites (Dated January 31, 2024), Molly Roby

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

2024 March 14 - Tennessee Weekly Drought Summary, Tennessee Climate Office, East Tennessee State University

Tennessee Climate Office Weekly Drought Summaries

No abstract provided.

Alternative Robust Ways Of Witnessing Nonclassicality In The Simplest Scenario, Massy Khoshbin, Lorenzo Catani, Matthew Leifer

Mathematics, Physics, and Computer Science Faculty Articles and Research

In this paper we relate notions of nonclassicality in what is known as the simplest nontrivial scenario (a prepare and measure scenario composed of four preparations and two binary-outcome tomographically complete measurements). Specifically, we relate the established method developed by Pusey [M. F. Pusey, Phys. Rev. A 98, 022112 (2018)] to witness a violation of preparation noncontextuality, that is not suitable in experiments where the operational equivalences to be tested are specified in advance, with an approach based on the notion of bounded ontological distinctness for preparations, defined by Chaturvedi and Saha [A. Chaturvedi and D. Saha, Quantum …

Re: Approval Letter For The Butte Priority Soils Operable Unit (Bpsou) Draft Final 2024 Type B Borrow Material Submittal #2 (Dated February 14, 2024), Molly Roby

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Β-Sheets Mediate The Conformational Change And Allosteric Signal Transmission Between The Aslov2 Termini, Sian Xiao, Mayar Terek Ibrahim, Gennady M. Verkhivker, Brian D. Zoltowski, Peng Tao

Mathematics, Physics, and Computer Science Faculty Articles and Research

Avena sativa phototropin 1 light-oxygen-voltage 2 domain (AsLOV2) is a model protein of Per-Arnt-Sim (PAS) superfamily, characterized by conformational changes in response to external environmental stimuli. This conformational change begins with the unfolding of the N-terminal A'α helix in the dark state followed by the unfolding of the C-terminal Jα helix. The light state is characterized by the unfolded termini and the subsequent modifications in hydrogen bond patterns. In this photoreceptor, β-sheets are identified as crucial components for mediating allosteric signal transmission between the two termini. Through combined experimental and computational investigations, the Hβ …

Density And Magnetic Field Asymmetric Kelvin‐Helmholtz Instability, Xuanye Ma, Peter Delamere, Katariina Nykyri, Antonius Otto, Stefan Eriksson, Lihui Chai, Brandon Burkholder, Andrew Dimmock, Yu-Lun Liou, Shiva Kavosi

Publications

The Kelvin‐Helmholtz (KH) instability can transport mass, momentum, magnetic flux, and energy between the magnetosheath and magnetosphere, which plays an important role in the solar‐wind‐ magnetosphere coupling process for different planets. Meanwhile, strong density and magnetic field asymmetry are often present between the magnetosheath (MSH) and magnetosphere (MSP), which could affect the transport processes driven by the KH instability. Our magnetohydrodynamics simulation shows that the KH growth rate is insensitive to the density ratio between the MSP and the MSH in the compressible regime, which is different than the prediction from linear incompressible theory. When the interplanetary magnetic field (IMF) …

Final 2024 Butte Priority Soils Operable Unit Type B Borrow Material Submittal #2, Pioneer Technical Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Medical Monitoring Working Group Meeting Minutes, Mike Mcanulty

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Draft Final 2024 Butte Priority Soils Operable Unit Helehan Borrow Submittal #2, Pioneer Technical Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

6d Single-Fluorogen Orientation-Localization Microscopy For Elucidating The Architecture Of Beta-Sheet Assemblies And Biomolecular Condensates, Tingting Wu, Weiyan Zhou, Jai S. Rudra, Rohit V. Pappu, Matthew D. Lew

Electrical & Systems Engineering Publications and Presentations

We develop six-dimensional single-molecule orientation-localization microscopy (SMOLM) to measure the 3D positions and 3D orientations simultaneously of single fluorophores. We show how careful optimization of phase and polarization modulation components can encode phase, polarization, and angular spectrum information from each fluorescence photon into a microscope’s dipole-spread function. We used the transient binding and blinking of Nile red (NR) to characterize the helical structure of fibrils formed by designed amphipathic peptides, KFE8^L and KFE8^D, and the pathological amyloid-beta peptide Aβ42. We also deployed merocyanine 540 to uncover the interfacial architectures of biomolecular condensates.

Novel Inhibitors To Mmpl3 Transporter Of Mycobacterium Tuberculosis By Structure-Based High-Throughput Virtual Screening And Molecular Dynamics Simulations, Hetanshi Choksi, Justin Carbone, Nicholas J. Paradis, Lucas Bennett, Candice Bui-Linh, Chun Wu

College of Science & Mathematics Departmental Research

Tuberculosis (TB)-causing bacterium Mycobacterium tuberculosis (Mtb) utilizes mycolic acids for building the mycobacterial cell wall, which is critical in providing defense against external factors and resisting antibiotic action. MmpL3 is a secondary resistance nodulation division transporter that facilitates the coupled transport of mycolic acid precursor into the periplasm using the proton motive force, thus making it an attractive drug target for TB infection. In 2019, X-ray crystal structures of MmpL3 from M. smegmatis were solved with a promising inhibitor SQ109, which showed promise against drug-resistant TB in Phase II clinical trials. Still, there is a pressing need to discover more …