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Veterinary Toxicology and Pharmacology Commons™
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- Acetaminophen (1)
- Annual ryegrass toxicity (1)
- Antibiotics (1)
- Buserelin (1)
- Developmental toxicity (1)
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- Drug tolerance (1)
- Equine medicine (1)
- FSH (1)
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- Kisspeptin (1)
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- Murrah buffaloes (1)
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Articles 1 - 4 of 4
Full-Text Articles in Veterinary Toxicology and Pharmacology
Kisspeptin Modulates Luteinizing Hormone Release And Ovarian Follicular Dynamics In Pre-Pubertal And Adult Murrah Buffaloes, Vishalkumar Pottapenjera, Srinivasa R. Rajanala, Chandrasekhar Reddy, Arunakumari Gangineni, Kiran Avula, Sandeep K. Bejjanki, Sriravali Sathagopam, Surabhi Kesharwani, Sathya Velmurugan
Kisspeptin Modulates Luteinizing Hormone Release And Ovarian Follicular Dynamics In Pre-Pubertal And Adult Murrah Buffaloes, Vishalkumar Pottapenjera, Srinivasa R. Rajanala, Chandrasekhar Reddy, Arunakumari Gangineni, Kiran Avula, Sandeep K. Bejjanki, Sriravali Sathagopam, Surabhi Kesharwani, Sathya Velmurugan
Pharmacology and Nutritional Sciences Faculty Publications
Kisspeptin is a neuropeptide that governs the reproductive axis upstream to GnRH. We wanted to study whether kisspeptin modulates plasma LH and FSH levels and ovarian follicular dynamics in buffaloes and whether kisspeptin can be used for fixed time artificial insemination (FTAI). We carried out these studies in comparison with buserelin, a potent GnRH agonist. Kisspeptin dose-dependently increased plasma LH levels. However, the kisspeptin-induced increase in LH was short-lived as the peak reached in 15–30 min returned to basal values by 1–2 h. The kisspeptin-induced increase in LH level was less compared to buserelin-induced increase in LH level which sustained …
30-Day Oral Acetaminophen Tolerance In Adult Horses, Sarah E. Foreman
30-Day Oral Acetaminophen Tolerance In Adult Horses, Sarah E. Foreman
Celebration of Learning
There are no controlled studies of acetaminophen toxicity in horses. The objective was to test the hypotheses that oral acetaminophen administered at a dosage 25% higher than that sometimes used in horses would result in measurable hepatic toxicity as seen in humans and other species. Six healthy adult horses were administered 25 mg/kg acetaminophen powder in corn syrup twice daily for 30 days. Three other horses served as negative controls receiving only corn syrup. Jugular venous blood samples were obtained on days 7 and 1 before treatment; on treatment days 1, 2, 5, 8, 12, 15, 19, 22, 26 and …
A Modular One-Generation Reproduction Study As A Flexible Testing System For Regulatory Safety Assessment, Richard Vogel, Troy Seidle, Horst Spielmann
A Modular One-Generation Reproduction Study As A Flexible Testing System For Regulatory Safety Assessment, Richard Vogel, Troy Seidle, Horst Spielmann
Troy Seidle, PhD
The European Union’s Registration, Evaluation and Authorisation of Chemicals (REACH) legislation mandates testing and evaluation of approximately 30,000 existing substances within a short period of time, beginning with the most widely used “high production volume” (HPV) chemicals. REACH testing requirements for the roughly 3000 HPV chemicals specify three separate tests for reproductive toxicity: two developmental toxicity studies on different animal species (OECD Test Guideline 414) and a two-generation reproduction toxicity study (OECD TG 416). These studies are highly costly in both economic and animal welfare terms. OECD TG 416 is a fertility study intended to evaluate reproductive performance of animals …
Argt Caused By Toxic Antibiodies : Research Report, P Vogel
Argt Caused By Toxic Antibiodies : Research Report, P Vogel
Journal of the Department of Agriculture, Western Australia, Series 4
A fortunate coincidence, discovered recently, has provided annual ryegrass toxicity researchers with valuable knowledge which may help them understand how the ARGT toxins affect animals, and further their investigations into vaccine development. A toxic antibiotic, identified years ago, has proved to be closely related to the ARGT toxins. Antibiotics are generally regarded as effective agents for the control of many bacterial and fungal infections. However, some of them are toxic to both the bacteria and the host, whether man or animal.