Other Veterinary Medicine Commons^™

The Past, Present, And Future Of Equine Science, Sarah H. White-Springer, Jason E. Bruemmer, Robert J. Coleman

USDA Wildlife Services: Staff Publications

A core group of 27 equine nutritionists and physiologists joined together in the late 1960s to formally address and enhance the direction of equine research, creating the Equine Nutrition and Physiology Soci- ety. In 2003, that growing society transformed into the Equine Science Society, which now serves as the preeminent, internationally recognized scientific equine organization. In recent years, it has been appre- ciated that equine science encompasses a wide range of focus areas, including exercise science, nutrition, genetics, reproductive physiology, teaching and extension, production and management, and mix of other specialties, qualified as biosciences. Additionally, trainees are highly valued in …

In Vitro Analysis Of Equine Platelet Rich Plasma And In Vivo Effect Of Cytokines After Repeated Intra-Articular Injections In Osteoarthritic Joints, Carlos Aguilar Miranda

LSU Master's Theses

INTRODUCTION- The use of biologic therapies like platelet rich plasma (PRP) has a potential benefit for the treatment of osteoarthritis in horses. However, key parts of it are still unknown. The objective is to evaluate the degree of platelet activation achieved when in contact with exogenous activators. As well as the long-term effect in the anabolism and catabolism of cytokines involved in equine osteoarthritis.

MATERIAL AND METHODS-In one in vitro study PRP was collected from 6-horses using a commercially available kit. Platelets were exposed to PBS as negative control or to varying concentrations of CaCl2. Activation was determined via cell …

The Use Of Papain And Benzyl Isothiocyanate As Anthelmintics For Equine Strongyles, Abigail Maxey

Undergraduate Honors Thesis Projects

Seeds of Carica papaya L. (Caricaceae) are a promising source of investigation for a novel anthelmintic to treat equine strongyle infestation. Strongyles are small redworms that attach to the intestinal wall in the equine. They can cause colic, poor hair coat, poor body condition, and, in severe cases, death. The objective of this study was to determine if benzyl isothiocyanate (BITC) and papain, two compounds found in papaya seeds, could be used to prevent migration of third stage cyathostome larvae (L3) in vitro using larval migration inhibition assays. The assays involved incubating larvae in solution, followed by larval migration through …

Development Of A Novel Ex Vivo Equine Corneal Model, Todd L. Marlo, Elizabeth A. Giuliano, Ajay Sharma, Rajiv R. Mohan

Pharmacy Faculty Articles and Research

Objective

To develop an ex vivo equine corneal organ culture model. Specifically, to assess the equine cornea's extracellular matrix and cellularity after 7 days using two different culture techniques: either (i) immersion system or (ii) air/liquid interface system, to determine the best ex vivo equine corneal model.

Animals Studied

Fourteen healthy equine corneas of various breeds.

Procedures

Equine corneas with 2 mm of perilimbal sclera were freshly harvested from 7 horses undergoing humane euthanasia. One corneal–scleral ring (CSR) from each horse was randomly placed in the (i) immersion condition organ culture system (IC), with the contralateral CSR being placed in …

Isolation And Cultivation Of Equine Corneal Keratocytes, Fibroblasts And Myofibroblasts, Dylan G. Buss, Elizabeth A. Giuliano, Ajay Sharma, Rajiv R. Mohan

Pharmacy Faculty Articles and Research

Objective—To establish an in vitro model for the investigation of equine corneal wound healing. To accomplish this goal, a protocol to isolate and culture equine corneal keratocytes, fibroblasts and myofibroblasts was developed.

Animal material—Equine corneal buttons were aseptically harvested from healthy research horses undergoing humane euthanasia for reasons unrelated to this study. Slit-lamp biomicroscopy was performed prior to euthanasia by a board-certified veterinary ophthalmologist to ensure that all samples were harvested from horses free of anterior segment disease.

Procedure—Equine corneal stroma was isolated using mechanical techniques and stromal subsections were then cultured. Customized media at different culture conditions was used …