Large or Food Animal and Equine Medicine Commons^™

Safety And Immunoreactivity Of A Xenogeneic Dna Plasmid Vaccine Expressing Human Tyrosinase In Tumor-Bearing Horses, Luis Miguel Lembcke Perez Prieto

Doctoral Dissertations

Melanomas are among the most common skin tumors in horses (second only to sarcoids), with prevalence rates reaching as high as 80% in adult gray horses. Despite the wide availability of measures of local control, there are currently no systemic therapies that can effectively prevent spread, or treat metastatic or locally advanced/non-resectable melanoma in horses. A form of gene immunotherapy based on a plasmid DNA construct containing a xenogeneic form of the antigen tyrosinase have been developed and optimized for targeting cancer in both humans and dogs; and have demonstrated significant immunoreactivity and clinical benefit in the treatment of melanocytic …

Determinación De Las Variables Fisiológicas En Potros De Raza Silla Argentina A Una Altitud De 2804 M.S.N.M, Cristy Johanna Sánchez Roa, Julio Cesar Álvarez Sanabria

Medicina Veterinaria

Hoy en día gracias a los avances de la ciencia y tecnología se han obtenido varios beneficios en el mundo equino, los cuales permiten realizar una mejor evaluación, estudio, análisis y seguimiento de la frecuencia cardiaca, respiratoria, temperatura y color de mucosas en equinos. Desafortunadamente estos valores fisiológicos en potros de raza Silla Argentina son escasos y los pocos que se encuentran en la literatura son datos estándar, que muy probablemente no se acoplan a la realidad del medio ya que el origen de esa información es de países con condiciones climáticas y razas muy diferentes a las que hay …

Estudio Retrospectivo Histopatológico De Enfermedades De Bovinos Y Equinos En La Universidad De La Salle, Diana Marcela Sanchez Ardila

Medicina Veterinaria

Se realizó el estudio de los casos de equinos y bovinos que ingresaron durante el periodo 2000 a 2011 para diagnóstico al Laboratorio de Histopatología de la Universidad de La Salle; 190 casos llegaron para estudio durante este periodo. Allí se encontraron 68.42% (130/190) casos pertenecientes a bovinos de los cuales 69.23% (90/130) de los casos fueron de necropsias y 30.76% (40/130) de biopsias. De los equinos se encontraron 31.57% (60/190) casos; 55% (33/60) necropsias y 45% (27/60) biopsias. Entre las causas 7 de muerte de los bovinos, los sistemas mas afectados fueron: El sistema respiratorio 30%, el sistema digestivo …

Kisspeptin Receptor Agonist (Ftm080) Increased Plasma Concentrations Of Luteinizing Hormone In Anestrous Ewes, Brian K. Whitlock, Kelly A. Chameroy, Rebecca R. Payton, Shinya Oishi, Nobutaka Fujii, Joseph A. Daniel

Brian K Whitlock, PhD, DVM, DACT

Kisspeptin (KP) and the KP receptor (Kiss1r) are integral to central regulation of the gonadotropic-axis. The demonstration that intravenous infusion of KP can stimulate gonadotropin secretion and ovulation in seasonally anestrous female sheep offers a means of manipulating the reproductive axis. However, KP may be of limited clinical use because of the short circulating half-life. Kiss1r agonists with increased half-life and similar efficacy to KP in vitro potentially may provide beneficial applications in breeding management of many species. However, many of these agonists have not been tested in vivo. This study was designed to test and compare the effects of …

Effect Of Meloxicam On Gain And Inflammatory Response Of Calves Castrated By Banding Post-Weaning, Brian K. Whitlock, Peter D. Krawczel, Jeff A. Carroll, Nicole C. Burdick Sanchez, Jeff W. Dailey, Joseph A. Daniel, Johann F. Coetzee

Brian K Whitlock, PhD, DVM, DACT

Castration may detrimentally affect the health and performance of weaned calves, and painful procedures are increasingly becoming a public concern. The objective of this study was to determine the effects of castration (by banding) with or without administration of meloxicam, a non-steroid anti-inflammatory, on performance and inflammatory response in weaned beef calves. Forty-eight (weaned) beef calves [10.0±0.2 mo old; 304±6 kg BW] were blocked by age, BW, wither height, scrotal circumference, and source, then randomly assigned to 1 of 3 treatments (n=16 calves per treatment: 1) intact bulls (BULL), 2) castration by banding (BAN), or 3) castration by banding with …

Effect Of Meloxicam On Gain And Behavior Of Calves Castrated By Banding Pre-Weaning, Joseph A. Daniel, Peter D. Krawczel, Brian K. Whitlock

Brian K Whitlock, PhD, DVM, DACT

The objective was to determine if oral meloxicam (M; a non-steroid anti-inflammatory) administered at castration of pre-weaning calves affected ADG or behavior. Prior to castration (14 d), Angus bulls were assigned to bull (BULL; n = 7; age 106 ± 6 d; BW = 174.2 ±7.7 kg; scrotal circumference 17.7 ± 0.4 cm), castrated (BAN; n = 12; age = 105 ± 5 d; BW = 144.5 ± 7.6 kg; scrotal circumference = 16 ± 0.4 cm) or castrated with meloxicam (BAN+M; n = 13; age = 121 ± 6 d; BW = 145.8 ± 6 kg; scrotal circumference = …

Meloxicam Mediates Short-Term Behavioral Changes Of Castrated Calves, Peter D. Krawczel, Jeff A. Carroll, Nicole C. Burdick Sanchez, Jeff W. Dailey, Joseph A. Daniel, Johann F. Coetzee, Brian K. Whitlock

Brian K Whitlock, PhD, DVM, DACT

Castration may detrimentally affect the health and performance of weaned calves and painful procedures are increasingly a public concern. Therefore, practical pain mitigation is critical. The objective was to determine the effects of castration (by banding) with or without administration of NSAID, meloxicam, on the behavior of weaned beef calves. Forty-eight (56 d post-weaning) beef calves [10.0 ± 0.2 (mean ± SE) mo old; 304 ± 6 kg BW] were blocked by multiple factors then randomly assigned to 3 treatments (n = 16 calves per treatment: 1) intact bulls (BULL), 2) castration by banding (BAN), or 3) castration by banding …

Determinación De Anticuerpos Anti-Diarrea Viral Bovina Dvb Mediante Elisa Competitivo En Una Población Cautiva De Venados Cola Blanca Odocoileus Virginianus En Cundinamarca, Colombia, Pedro Enrique Navas Suárez

Medicina Veterinaria

Colombia posee tres géneros de cérvidos: Mazama sp., Odocoileus sp. y Pudu sp.; el venado coliblanco (Odocoileus virginianus) se encuentra distribuido en las regiones Andina y Orinoquia; la lista roja de la Unión Internacional para la Conservación Natural (UICN) lo categoriza como una especie de preocupación menor (LC); dentro de su área de distribución, se encuentran regiones de explotaciones bovinas extensivas, las cuales pueden favorecer el contacto directo entre venados y bovinos, generando un riesgo para la interfaz animal domésticoanimal silvestre, y de esta manera iniciar ciclos de transmisión de patógenos, dentro de los cuales el virus de la Diarrea …

Plan De Acción Para Implementación De Un Banco De Calostro En El Criadero Caballar Mancilla Policía Nacional, Diana Alejandra Pastrana Pacabaque

Medicina Veterinaria

Visando las necesidades de implementar un banco de calostro en el Criadero Caballar Mancilla de la Policía Nacional, se planteó en el presente trabajo el objetivo de suplir las necesidades del potro recién nacido cuando hayan sido detectadas fallas en la trasferencia de la inmunidad pasiva, a partir del análisis de la concentración de inmunoglobulinas en el calostro, y evaluando los niveles de absorción en el potro después de haberlo consumido. Para el desarrollo de este proyecto se recolectó calostro de las mejores yeguas del criadero con las características ideales como condición corporal y peso, se analizó la composición del …

Evaluación Del Folículo Preovulatorio Y Efecto Del Deslorelin Como Inductor De La Ovulación En 12 Yeguas Silla Argentina En El Municipio De Facatativá, Cundinamarca, Martin Jaramillo Londoño, Juan Felipe Perez Mayor

Medicina Veterinaria

La yegua es considerada una especie poliéstrica estacional, de tal manera que exhibe actividad ovárica máxima durante primavera y verano, y periodos de no actividad en los meses de invierno como respuesta a mayor liberación de melatonina, lo que genera una disminución en la liberación de GnRH y, por lo tanto, de FSH y LH. Aunque bajo condiciones tropicales no se ha observado estacionalidad debido a la poca oscilación del fotoperiodo durante el año, otros factores como la nutrición, temperatura e historia de estacionalidad pueden generar disminución en la actividad ovárica, especialmente en las yeguas importadas desde países lejanos a …

Determinación De Géneros De Endoparásitos Gastrointestinales Y Pulmonares Presentes En Los Equinos Del Batallón Gmsil De Bonza, Duitama Boyacá, Carlos Andrés Sánchez Tautiva, Carlos Eduardo Cardona Hernández

Medicina Veterinaria

Los equinos son susceptibles de infecciones parasitarias, las mismas dependen del ciclo biológico de los parásitos, grado de infección, carga parasitaria, género del parásito, susceptibilidad del huésped, clima, geografía, alimentación, entre otros. Una vez establecidas las infecciones en el huésped éste disminuye su productividad, desarrollo y función zootécnica lo que deriva en pérdidas económicas dentro de un sistema productivo. El siguiente trabajo de investigación identificó los géneros de parásitos gastrointestinales y pulmonares presentes en el Batallón General José Miguel Silva Plazas. Para ello se recolectaron muestras de materia fecal directamente del recto de los 80 animales presentes en el Batallón …

Nebraska Bqa: Herd Health Plan/Protocol, Rob Eirich

Nebraska Beef Quality Assurance Program

Nebraska cattlemen have demonstrated a commitment to the integrity of today's beef products by implementing sound cattle management practices. Consumers are looking for beef raised in a healthy and safe environment. An appropriate Herd Health Plan/Protocol ensures that all cattle are raised in the best health.

Nebraska Bqa: Veterinarian Client Patient Relationship, Rob Eirich

Nebraska Beef Quality Assurance Program

Beef producers are committed producing a high quality, safe and wholesome beef product. A commitment to herd health and veterinary input is critical to achieving this goal. To this end, developing a veterinarian client-patient relationship (VCPR) is important and will benefit all aspects of cattle performance. Veterinarians' working understanding of cattle disease and parasites can help cattle raisers develop targeted vaccination and treatment programs.

Determination Of Farm-Specific Lawsonia Intracellularis Seroprevalence In Central Kentucky Thoroughbreds And The Identification Of Factors Contributing To Equine Proliferative Enteropathy, Allen E. Page

Theses and Dissertations--Veterinary Science

Lawsonia intracellularis and the disease it causes in horses, equine proliferative enteropathy (EPE), is an emerging pathogen of increasing importance to the horse industry from both an economic and welfare standpoint. Long recognized as an economically important disease of swine, the hallmark of EPE is a protein-losing enteropathy, where affected horses suffer weight loss and some ultimately succumb to the disease despite aggressive treatment. There are currently no known EPE preventative measures and the epidemiology of the disease remains poorly defined. While EPE is a sporadic disease affecting less than 25% of exposed horses, some farms experience clinical cases year …

Effect Of Beef Heifer Development System On Adg, Reproduction, And Feed Efficiency During First Pregnancy, Adam F. Summers, T. L. Meyer, Stetson P. Weber Weber, Rick N. Funston

Nebraska Beef Cattle Reports

This study evaluated the effect of post-weaning development system on heifer ADG, reproductive performance, and subsequent feed efficiency as a pregnant heifer. Heifers were developed on dormant pasture and grazed corn residue or dormant pasture and placed in a drylot. The following winter, a subset of pregnant heifers were placed in a Calan Broadbent individual feeding system during late gestation. Drylot-developed heifers had greater BW from pre-breeding through pregnancy diagnosis and greater overall ADG during development. However, there was no difference in reproductive performance. Pre-calving BW, ADG, and G:F tended to be greater for drylot heifers. Heifers developed on corn …

Hormonal Residues In Feedlot Pens And Runoff, Terry L. Mader, Leslie J. Johnson, Shannon L. Bartelt-Hunt Hunt, Daniel D. Snow, William L. Kranz, Charles A. Shapiro, Simon Van Donk, David P. Shelton, David Tarkalson, Tian Zhang

Nebraska Beef Cattle Reports

Two identically designed trials were conducted in separate years at the University of Nebraska Haskell Agricultural Laboratory, Concord, Neb., using 192 crossbred heifers (96/trial). Within a trial, heifers were assigned randomly to 2 groups (3 pens/group): 1) treatment (TRT) animals were administered synthetic hormones via subcutaneous implants (Ralgro and Revalor-H) and fed Melengesterol Acetate (MGA), or 2) control (CON) animals with no synthetic hormone provided.

Gains and feed conversions were 18.8 and 7.5% better, respectively, for TRT, while CON had 16.7% greater choice and prime carcasses. In runoff samples, progesterone was greater for CON. With the exception of androsterone, average …

Effect Of Development System On Heifer Performance And Primiparous Heifer Grazing Behavior, Adam F. Summers, T. L. Meyer, Jacqueline Musgrave Musgrave, Stetson P. Weber, Rick N. Funston

Nebraska Beef Cattle Reports

The effect of heifer development system on primiparous heifer performance grazing corn residue during late gestation was investigated. Weaned heifers grazing corn residue tended to have reduced final BW after corn residue grazing compared to heifers grazing winter range. However reproductive performance for the two treatments was similar. When grazing corn residue as pregnant heifers during late gestation, heifers developed on corn residue had improved ADG compared to drylot-developed heifers and tended to have increased ADG compared to winter range-developed heifers. Adaptation to corn residue grazing as a developing heifer improves primiparous heifer performance grazing corn residue during late gestation.

Applying Corn Condensed Distillers Solubles To Hay Windrows Prior To Baling: Ii. Effects On Growing Cattle Performance, Jason M. Warner, Cody J. Schneider, Richard J. Rasby Rasby, Galen E. Erickson, Terry J. Klopfenstein, Mark Dragastin

Nebraska Beef Cattle Reports

Two experiments evaluated the feeding value of grass hay bales previously treated with CCDS in growing cattle diets. In Experiment 1, heifers fed bales treated with 20% CCDS (DM) gained less than those fed an equal level of dried distillers grains plus solubles and nontreated hay. In Experiment 2, ADG and F:G linearly improved with increasing CCDS levels. Furthermore, supplementing cattle to meet metabolizable protein requirements when fed diets of CCDS and hay did not improve ADG at levels greater than 15% CCDS. Data indicate hay bales previously treated with CCDS are adequate for use in growing diets, confirming that …

Field Peas As A Binder For Dried Distillers Grains-Based Range Cubes, Alex H. Titlow, Jacob A. Hansen, Matt K. Luebbe Luebbe, Karla Jenkins

Nebraska Beef Cattle Reports

A grazing study was conducted to determineif field peas are a good naturalbinder for dried distillers grains-based range cubes. Cattle supplemented dried distillers grains in the bunk or a 25% field pea/75% distillers grains cube fed on the ground gained similarly and outgained cattle supplemented dried distillers on the ground. A 25.6% loss of the distillers grains fed loose on the ground was estimated. The similar performance of cattle fed distillers grains in the bunk and those fed pea/distillers cube on the ground suggests field peas reduced distillers grains loss and therefore are an acceptable binder for distillers grains based …

Economic Analysis Update: Supplementing Distillers Grains To Grazing Yearling Steers, Stephanie K. Moore, Andrea K. Watson, Terry Klopfenstein Klopfenstein, Galen E. Erickson, Walter H. Schacht

Nebraska Beef Cattle Reports

A seven-year study from 2005-2011 was conducted to evaluate four grazing management strategies for backgrounding yearling steers on smooth bromegrass pastures. Economic budgets were used to calculate profit differences with current (April 2012) market prices. Overall, cattle receiving supplement had greater net returns, lower cost of gain, and lower breakeven prices. In recent years fertilizer prices have increased at a greater rate than land costs in Nebraska, making it more economical to use a lower stocking rate instead of fertilizing pastures. As land prices increase, the incentive to use either N fertilizer or DDGS supplementation increases.

Corn Residue Removal Effects On Subsequent Yield, Brian J. Wienhold, Gary E. Varvel, Virginia L. Jin Jin, Rob B. Mitchell, Kenneth P. Vogel

Nebraska Beef Cattle Reports

Corn residue is used for forage and feed, but residue removal effects on soil properties and yield is a concern. Residue removal effects on corn yields and soil organic carbon is site specific. Removing 50% of the residue from rain fed sites reduced corn yield by 1.9 bu/ac, whereas removing 40% of the residue from irrigated sites increased corn yield by 15.4 bu/ac. However, removing 53% of the residue increased soil erosion by 30%. Agronomic practices such as reduced tillage, cover crops, or manure may offset residue removal impacts. Residue removal should be based on site-specific characteristics and management, but …

Evaluation Of A New Chemistry For Rangeland Grasshopper Control, Jeffrey Bradshaw, Karla Jenkins, Sean Doyle Whipple Whipple, Rick Patrick

Nebraska Beef Cattle Reports

A grasshopper control study was conducted to evaluate the effectiveness of a new class of systemic chemical. The new pesticide Prevathon^® (high and low levels) was compared to Coragen^®, Dimilin^®, and a nontreated check. Grasshoppers were numerically reduced the most by Coragen and Prevathon, though not significant. The highest level of Prevathon did not numerically impact beneficial insects in general. Biomass and forage quality were not significantly impacted by chemical treatment. However, forage biomass was numericallygreatest for the highest level of Prevathon. Prevathon appears to be an acceptable systemic pesticide for grasshopper control with minimal …

Replacing Steam-Flaked Corn And Dry Rolled Corn With Condensed Distillers Solubles In Finishing Diets, Alex H. Titlow, Adam L. Shreck, Stephanie A. Furman Furman, Karla Jenkins, Matt K. Luebbe, Galen E. Erickson

Nebraska Beef Cattle Reports

The interaction between corn processing method and condensed distillers solubles (CDS) was evaluated using either steam-flaked corn (SFC) or dry rolled corn (DRC). As CDS replaced corn at either 15 or 30% of the diet DM, DMI intake decreased quadratically for both SFC and DRC. Within DRC- based diets, ADG increased quadratically with 15% CDS being greatest and F:G improved quadratically with 30% inclusion being best. When SFC was used as the grain source, ADG increased linearly and F:G improved quadratically with increasing levels of CDS. A greater performance response was observed with SFC compared to DRC when feeding increased …

Effects Of Feeding 44 G/Ton Rumensin® During Grain Adaptation On Animal Performance And Carcass Characteristics, Cody J. Schneider, Matt K. Luebbe, Karla Jenkins Jenkins, Stephanie A. Furman, Galen E. Erickson

Nebraska Beef Cattle Reports

Cattle were adapted to a finishing diet over 20 days while feeding 33 or 44 g/ton (DM) of Rumensin. Following grain adaptation, all cattle were fed a common finishing diet containing 33 g/ton Rumensin for the remainder of the feeding period. Feeding 44 g/ton of Rumensin during the adaptation period did not affect performance during the adaptation period or over the entire feeding period when compared to the 33 g/ton adaptation level.

Including Next Enhance® Essential Oils In Finishing Diets On Performance With Or Without Rumensin® And Tylan®, Curtis J. Bittner, Galen E. Erickson, Karla Jenkins Jenkins, Matt K. Luebbe, Troy Wistuba

Nebraska Beef Cattle Reports

Finishing cattle performance was evaluated using NEXT ENHANCE essential oils in finishing diets. Treatments consisted of 1) control (CON), 2) NEXT ENHANCE at 300 mg/day (NE), 3) Rumensin and Tylan at 360 and 90 mg/day, respectively (RT), or 4) NEXT ENHANCE plus Rumensin and Tylan (NERT). No NEXT ENHANCE by Rumensin/Tylan interaction was observed. Steers fed Rumensin/Tylan had decreased F:G and increased live final BW and marbling score. The prevalence of liver abscesses decreased 46% when steers were fed Rumensin/Tylan. Including NEXT ENHANCE in finishing diets did not impact performance or carcass characteristics.

The Effect Of Commensal Microbial Communities On The Fecal Shedding Of Shiga Toxin-Producing E. Coli (Stec) In Beef Cattle, Nirosh D. Aluthge, Yoshitha A. Wanniarachchi, Brandon L. Nuttelman Nuttelman, Cody J. Schneider, Terry Klopfenstein, Galen E. Erickson, Jayne E. Stratton, Samodha C. Fernando

Nebraska Beef Cattle Reports

This ongoing study compares the gut microbial community composition between shedding steers high in shiga toxin-producing E. coli (STEC) counts and low-shedding steers. Shedders were identified among 170 beef animals over three time periods using selective microbiological culture media. The isolated bacterial cultures were confirmed to be STEC using PCR, 16s rRNA sequencing and a shiga toxin immunoassay. The most abundant strains found in the cattle feces were those belonging to the serogroups O111 (40.3%) and O157:H7 (37.3%), with O103 (8.3%), O26 (6.0%), O83 (4.5%), and O55 (3.0%) being detected in much lower numbers . Out of the 52 animals …

Anaerobic Digestion Of Finishing Cattle Manure, Andrea K. Watson, Galen E. Erickson, Terry Klopfenstein Klopfenstein, Samodha C. Fernando, Jana L. Harding

Nebraska Beef Cattle Reports

Utilizing manure from cattle fed distillers grains in anaerobic digesters improved methane production and DM degradation of manure compared to manure from cattle fed no distillers grains. Manure from cattle fed in open lot pens had soil contamination which decreased OM content and led to decreased total methane production (L/day), but not when expressed as methane/g OM. If ash buildup is avoided, open lot manure can be used as anaerobic digester feedstock.

Current Therapeutic Approaches To Equine Protozoal Myeloencephalitis, L. Dirikolu, Jonathan H. Foreman, Thomas Tobin

Maxwell H. Gluck Equine Research Center Faculty Publications

Equine protozoal myeloencephalitis is the most important infectious neurologic disease of horses in the Western Hemisphere. Equine protozoal myeloencephalitis can interfere with a horse's ability to race, work, and perform; untreated, EPM can be lethal. Antemortem diagnosis of EPM is challenging, requiring careful evaluation of the animal's history, clinical signs, and laboratory data, with rigorous exclusion of other causes.

Therapeutic approaches to EPM are evolving. First-generation therapeutic approaches for EPM were based on the classic anti–Toxoplasma gondii pyrimethamine–sulfonamide combinations; treatment is prolonged and can be associated with a considerable relapse rate, which may be associated with the difficulty in …

Chondrodysplasia-Like Dwarfism In The Miniature Horse, John E. Eberth

Theses and Dissertations--Veterinary Science

Dwarfism is considered one of the most recognized congenital defects of animals and humans and can be hereditary or sporadic in cause and expression. There are two general morphologic categories within this vastly diverse disease. These categories are disproportionate and proportionate dwarfism and within each of these there are numerous phenotypes which have been extensively described in humans, and to a lesser extent in dogs, cattle, mice, chickens, and other domestic species. Ponies and Miniature horses largely differ from full size horses only by their stature. Ponies are often defined as those whose height is not greater than 14.2 hands; …

Heifers With Low Antral Follicle Counts Have Low Birth Weights And Produce Progeny With Low Birth Weights, Adam F. Summers, Robert A. Cushman, Karl Moline Moline, Jeff Bergman, Andrea S. Cupp

Nebraska Beef Cattle Reports

To determine the relationship of antral follicle count and heifer BW, reproductive tract characteristics, and first-calf performance, Red Angus-composite heifers were used over three years. High antral follicle count heifers had greater BW from birth through pre-breeding. Progeny birth BW was greater for calves born to high antral follicle count heifers compared to low antral follicle count heifers. Taken together these data indicate a relationship between antral follicle counts and BW through the first breeding season and corresponding progeny, and continues to support a possible link between genes that influence growth and development and establishment of ovarian reserve.