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Translational Medical Research Commons™
Open Access. Powered by Scholars. Published by Universities.®
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Articles 151 - 180 of 208
Full-Text Articles in Translational Medical Research
Remote Video Monitoring Is Another Example Of “Dying On The Machine” For Critically Ill Patients, Noveera A. Mirza, Joshua A. Christian, Christopher M. Lajeunesse
Remote Video Monitoring Is Another Example Of “Dying On The Machine” For Critically Ill Patients, Noveera A. Mirza, Joshua A. Christian, Christopher M. Lajeunesse
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Hardin SR, Dienemann J, Rudisill P, Mills KK. Inpatient fall prevention: use of in-room webcams. J Patient Saf. 2013 Mar;9(1):29-35. doi: 10.1097/PTS.0b013e3182753e4f
Patient-Controlled Analgesia Improves Pain Control In A Vaso-Occlusive Crisis In Sickle Cell Patients, Rujul H. Parikh
Patient-Controlled Analgesia Improves Pain Control In A Vaso-Occlusive Crisis In Sickle Cell Patients, Rujul H. Parikh
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of van Beers EJ, van Tuijn CF, Nieuwkerk PT, Friederich PW, Vranken JH, Biemond BJ. Patient-controlled analgesia versus continuous infusion of morphine during vaso-occlusive crisis in sickle cell disease, a randomized controlled trial. Am J Hematol. 2007;82(11):955-60. doi: 10.1002/ajh.20944
Hydroxyurea Lowers The Frequency Of Sickle Cell Vaso-Occlusive Crises, Corey S. Macrander
Hydroxyurea Lowers The Frequency Of Sickle Cell Vaso-Occlusive Crises, Corey S. Macrander
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Charache S, Terrin ML, Moore RD, et al. Effect of hydroxyurea on the frequency of painful crises in sickle cell anemia. N Engl J Med 1995;(332):1317-1322 doi: 10.1056/nejm199505183322001
Clopidogrel Alone Is Safer Than Clopidogrel And Aspirin For Secondary Prevention Of Acute Ischemic Stroke., Bradford J. Woelke, Daniel Angell Do, Katherine Litow Md
Clopidogrel Alone Is Safer Than Clopidogrel And Aspirin For Secondary Prevention Of Acute Ischemic Stroke., Bradford J. Woelke, Daniel Angell Do, Katherine Litow Md
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Diener HC, Bogousslavsky J, Brass LM, et al. Aspirin and clopidogrel compared with clopidogrel alone after recent ischaemic stroke or transient ischaemic attack in high-risk patients (MATCH): randomised, double-blind, placebo-controlled trial. Lancet. 2004;364(9431):331-337. doi: 10.1016/s0140-6736(04)16721-4
Quality? Safety? Stop Being Naïve., Rana K. Zaban Do, Steven Istephan, Jonathan Serman Md
Quality? Safety? Stop Being Naïve., Rana K. Zaban Do, Steven Istephan, Jonathan Serman Md
Clinical Research in Practice: The Journal of Team Hippocrates
The first day of our inpatient medicine rotation, the Emergency Department (ED) admitted a patient to a general medical floor without notifying our rounding team. We used the institution’s system improvement tracking software to draw attention to communication breakdown in the interest of patient safety. This piece illustrates how there is a prominent hierarchy in medicine; it is inherent to the framework of the way in which hospitals function. A discussion ensues with our attending physician supervisor on our patient medicine service. During this discussion, we ponder whether it is possible to impact quality and safety from our position as …
Treating Diabetic Ketoacidosis With Subcutaneous Insulin?, Marlene Aziza Azar
Treating Diabetic Ketoacidosis With Subcutaneous Insulin?, Marlene Aziza Azar
Clinical Research in Practice: The Journal of Team Hippocrates
The author examines the evidence for treating diabetic ketoacidosis with subcutaneous insulin vs IV insulin.
Reframing Outcome Measures For Thrombolytics In Acute Ischemic Stroke, Brandon Baker, Charles W. Kropf, Nicholus Yee, James Peter Meza
Reframing Outcome Measures For Thrombolytics In Acute Ischemic Stroke, Brandon Baker, Charles W. Kropf, Nicholus Yee, James Peter Meza
Clinical Research in Practice: The Journal of Team Hippocrates
An informed consent conversation examining relevant research and discussing the potential benefits and harms of thrombolytic therapy in acute stroke.
It Is Not Necessary To Use Both An Ivc Filter And Anticoagulation Therapy For Severe Pulmonary Embolism, Radhika Sharma
It Is Not Necessary To Use Both An Ivc Filter And Anticoagulation Therapy For Severe Pulmonary Embolism, Radhika Sharma
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Mismetti P, Laporte S, Pellerin O, et al. Effect of a retrievable inferior vena cava filter plus anticoagulation vs anticoagulation alone on risk of recurrent pulmonary embolism: a randomized clinical trial. JAMA. 2015;313(16):1627–1635. doi: 10.1001/jama.2015.3780
Compared To Maximal Current Management Standards, Oscillating Positive Expiratory Pressure Devices Have Not Been Shown To Improve Clinically Relevant Outcomes In Copd Patients With Acute Exacerbation, Daniel P. Noack, Gaybriel Newton
Compared To Maximal Current Management Standards, Oscillating Positive Expiratory Pressure Devices Have Not Been Shown To Improve Clinically Relevant Outcomes In Copd Patients With Acute Exacerbation, Daniel P. Noack, Gaybriel Newton
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Ambrosino N, Callegari G, Galloni C, Brega S, Pinna G. Clinical evaluation of oscillating positive expiratory pressure for enhancing expectoration in diseases other than cystic fibrosis. Monaldi Arch Chest Dis. 1995;50(4):269-275.
Anticoagulation Increases Survival In Patients With Idiopathic Pulmonary Arterial Hypertension, Marvin L. Kajy
Anticoagulation Increases Survival In Patients With Idiopathic Pulmonary Arterial Hypertension, Marvin L. Kajy
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Olsson KM, Delcroix M, Ghofrani HA, et al. Anticoagulation and survival in pulmonary arterial hypertension: Results from the Comparative, Prospective Registry of Newly Initiated Therapies for Pulmonary Hypertension (COMPERA). Circulation, 2014;129(1):57-65. doi: 10.1161/CIRCULATIONAHA.113.004526
From The Editor: Context Creates Meaning For Evidence, James Peter Meza
From The Editor: Context Creates Meaning For Evidence, James Peter Meza
Clinical Research in Practice: The Journal of Team Hippocrates
Introducing "Informed Consent" manuscripts and an expanded remit for the Journal.
Low Molecular-Weight Heparin Is Better Than Warfarin For Prevention Of Recurrent Venous Thromboembolism In Cancer Patients, Sarah Choi
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Lee AYY, Levin MN, Bake RI, et al. Low-molecular-weight heparin versus a coumarin for the prevention of recurrent venous thromboembolism in patients with cancer. N Engl J Med. 2003;349:146-153. doi: 10.1056/NEJMoa025313
The Ethics Of Offering Futile Treatment, Rebekah L. Eddy, Viktoria Krajnc, Lauren Smith
The Ethics Of Offering Futile Treatment, Rebekah L. Eddy, Viktoria Krajnc, Lauren Smith
Clinical Research in Practice: The Journal of Team Hippocrates
It important to acknowledge our own emotional biases and be cognizant of how we present evidence-based options to patients and their families, so that they may provide truly informed consent.
Stem Cell Therapy For End Stage Copd: A Cautionary Tale Of Direct-To-Consumer Advertising, Blake J. Arthurs, Scott Yaekle
Stem Cell Therapy For End Stage Copd: A Cautionary Tale Of Direct-To-Consumer Advertising, Blake J. Arthurs, Scott Yaekle
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Weiss DJ, Casaburi R, Flannery R, LeRoux-Williams M, Tashkin DP. A placebo-controlled, randomized trial of mesenchymal stem cells in COPD. Chest. 2013;143(6):1590-1598. doi: 10.1378/chest.12-2094
It Is Reasonable To Recommended Intrapleural Alteplase For Loculated Pleural Effusions, Tricia Fernandez
It Is Reasonable To Recommended Intrapleural Alteplase For Loculated Pleural Effusions, Tricia Fernandez
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Thommi G, Shehan J, Robison K, Christensen M, Backemeyer L, McLeay M. A double blind randomized cross over trial comparing rate of decortication and efficacy of intrapleural instillation of alteplase vs placebo in patients with empyemas and complicated parapneumonic effusions. Respir Med. 2012;17(2):716-723. doi: 10.1016/j.rmed.2012.02.005
Combination Octreotide, Midodrine, And Albumin May Improve Survival In Patients With Hepatorenal Syndrome, But The Evidence Is Weak, Jacob Szafranski
Combination Octreotide, Midodrine, And Albumin May Improve Survival In Patients With Hepatorenal Syndrome, But The Evidence Is Weak, Jacob Szafranski
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Skagen C, Einstein M, Lucey MR, Said A. Combination treatment with octreotide, midodrine, and albumin improves survival in patients with type 1 and type 2 hepatorenal syndrome. J Clin Gastroenterol. 2009 Aug;43(7):680-5. doi: 10.1097/MCG.0b013e318188947c
We Have No Real Evidence Related To Anticoagulation Plus Aspirin For Stroke Prevention In Atrial Fibrillation, Yuxiang Wang
We Have No Real Evidence Related To Anticoagulation Plus Aspirin For Stroke Prevention In Atrial Fibrillation, Yuxiang Wang
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Flaker GC, Gruber M, Connolly SJ, et al. Risks and benefits of combining aspirin with anticoagulant therapy in patients with atrial fibrillation: an exploratory analysis of stroke prevention using an oral thrombin inhibitor in atrial fibrillation (SPORTIF) trials. Am Heart J. 2006;152:967-973. doi: 10.1016/j.ahj.2006.06.024
Manage Terminal Ileum Diverticulitis Comparably To Diverticulitis Elsewhere, James Yip
Manage Terminal Ileum Diverticulitis Comparably To Diverticulitis Elsewhere, James Yip
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Park HC, Lee BH. The management of terminal ileum diverticulitis. Am Surg. 2009 Dec;75(12):1199-202.
From The Editor, James Peter Meza
From The Editor, James Peter Meza
Clinical Research in Practice: The Journal of Team Hippocrates
With this issue of the Journal, we expand types of submissions to include generalizable knowledge in the form of brief reports and original research.
Educating Clinician Scientists Once Again—A Societal Need, James Peter Meza
Educating Clinician Scientists Once Again—A Societal Need, James Peter Meza
Clinical Research in Practice: The Journal of Team Hippocrates
The Faculty Editor advocates for the training of clinician scientists again, using the body of clinical research as the laboratory.
Earth Suit, Bowhee Gwak, Young Park
Earth Suit, Bowhee Gwak, Young Park
Clinical Research in Practice: The Journal of Team Hippocrates
The authors reflect on an experience learning at the feet of a spirited patient.
Critical Appraisal Is A Skill That Takes Practice: Our Patients Are Counting On Us, Dorothy Bourdet
Critical Appraisal Is A Skill That Takes Practice: Our Patients Are Counting On Us, Dorothy Bourdet
Clinical Research in Practice: The Journal of Team Hippocrates
A fumbling attempt at critical analysis in support of a clinical decision crystallizes the author's understanding that skillful analysis of research is crucial to good practice.
Early Haart Should Be Used For Treatment-Naive Hiv Patients With Pneumocystis Pneumonia, Maxwell L. Winkler
Early Haart Should Be Used For Treatment-Naive Hiv Patients With Pneumocystis Pneumonia, Maxwell L. Winkler
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Manzardo C, Esteve A, Ortega N, et al. Optimal timing for initiation of highly active antiretroviral therapy in treatment-naïve human immunodeficiency virus-1-infected individuals presenting with AIDS-defining diseases: the experience of the PISCIS Cohort. Clin. Microbiol. Infect. 2013 July;19(7):646-653. doi: 10.1111/j.1469-0691.2012.03991.x
Pharmacologic Diuresis Is Safer Than Ultrafiltration For Cardiorenal Syndrome, Grace Choong
Pharmacologic Diuresis Is Safer Than Ultrafiltration For Cardiorenal Syndrome, Grace Choong
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Bart BA, Goldsmith SR, Lee KL et al. Ultrafiltration in decompensated heart failure with cardiorenal syndrome. N Engl J Med. 2012;367:2296-2304. doi: 10.1056/NEJMoa1210357
Spinal Compression Fractures: No Additional Pain Relief With Use Of Back Braces, Kayla A. Berigan, Brandon Baker, Zakaria Ahmad, Aaron Simpson
Spinal Compression Fractures: No Additional Pain Relief With Use Of Back Braces, Kayla A. Berigan, Brandon Baker, Zakaria Ahmad, Aaron Simpson
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Li M, Law SW, Cheng J, Kee HM, Wong MS. A comparison study on the efficacy of SpinoMed® and soft lumbar orthosis for osteoporotic vertebral fracture. J. Prosthet. Orthot. Int. 2015;39(4):270-276. doi: 10.1177/0309364614528204
Anticoagulation Following Gastrointestinal Bleeding: Assessing Harms And Benefits, Jacob Jeffers
Anticoagulation Following Gastrointestinal Bleeding: Assessing Harms And Benefits, Jacob Jeffers
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Sengupta N, Feuerstein JD, Patwardhan VR, et al. The risks of thromboembolism vs. recurrent gastrointestinal bleeding after interruption of systemic anticoagulation in hospitalized in patients with gastrointestinal bleeding: a prospective study. Am. J. Gastroenterol. 2014;110:328-335. doi: 10.1038/ajg.2014.398
Restriction Therapy In Acute Heart Failure Is Not Shown To Be Effective, Amrit K. Basi, Colleen W. Harkreader, Nicholus H. Yee M.D., Shadia A. Yeihey M.D., Suraiya K. Azom M.D.
Restriction Therapy In Acute Heart Failure Is Not Shown To Be Effective, Amrit K. Basi, Colleen W. Harkreader, Nicholus H. Yee M.D., Shadia A. Yeihey M.D., Suraiya K. Azom M.D.
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Travers B, O’Loughlin C, Murphy NF, et al. Fluid restriction in the management of decompensated heart failure: no impact on time to clinical stability. J Card Fail. 2007;13(2):128-132. doi: 10.1016/j.cardfail.2006.10.012
Vedolizumab Should Be The Next Line Agent For The Treatment Of Refractory Crohn’S Disease, Mitchell Kentor
Vedolizumab Should Be The Next Line Agent For The Treatment Of Refractory Crohn’S Disease, Mitchell Kentor
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Shelton E, Allegretti J, Stevens B et al. Efficacy of Vedolizumab as Induction Therapy in Refractory IBD Patients. Inflammatory Bowel Diseases. 2015 Dec;21(12):2879-2885. doi:10.1097/mib.0000000000000561
Statin Therapy For Elderly Patients Should Be Assessed For Each Individual, Raymond Gong
Statin Therapy For Elderly Patients Should Be Assessed For Each Individual, Raymond Gong
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Shepherd J, Blauw GJ, Murphy MB, et al. Pravastatin in elderly individuals at risk of vascular disease (PROSPER): a randomised controlled trial. Lancet. 2002;360(9346):1623-30. doi:10.1016/S0140-6736(02)11600-X
It Is Reasonable To Treat Patients With Type 1 Hepatorenal Syndrome With Midodrine And Octreotide, William Kane
It Is Reasonable To Treat Patients With Type 1 Hepatorenal Syndrome With Midodrine And Octreotide, William Kane
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Esrailian E, Pantangco ER, Kyulo NL, Hu KQ, Runyon BA. Octreotide/midodrine therapy significantly improves renal function and 30-day survival in patients with type 1 hepatorenal syndrome. Dig Dis Sci. 2007;52(3):742-748. doi: 10.1007/s10620-006-9312-0