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Translational Medical Research Commons

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Wayne State University

Journal

2016

Articles 1 - 23 of 23

Full-Text Articles in Translational Medical Research

Educating Clinician Scientists Once Again—A Societal Need, James Peter Meza Nov 2016

Educating Clinician Scientists Once Again—A Societal Need, James Peter Meza

Clinical Research in Practice: The Journal of Team Hippocrates

The Faculty Editor advocates for the training of clinician scientists again, using the body of clinical research as the laboratory.


Earth Suit, Bowhee Gwak, Young Park Oct 2016

Earth Suit, Bowhee Gwak, Young Park

Clinical Research in Practice: The Journal of Team Hippocrates

The authors reflect on an experience learning at the feet of a spirited patient.


Critical Appraisal Is A Skill That Takes Practice: Our Patients Are Counting On Us, Dorothy Bourdet Sep 2016

Critical Appraisal Is A Skill That Takes Practice: Our Patients Are Counting On Us, Dorothy Bourdet

Clinical Research in Practice: The Journal of Team Hippocrates

A fumbling attempt at critical analysis in support of a clinical decision crystallizes the author's understanding that skillful analysis of research is crucial to good practice.


Early Haart Should Be Used For Treatment-Naive Hiv Patients With Pneumocystis Pneumonia, Maxwell L. Winkler Aug 2016

Early Haart Should Be Used For Treatment-Naive Hiv Patients With Pneumocystis Pneumonia, Maxwell L. Winkler

Clinical Research in Practice: The Journal of Team Hippocrates

A critical appraisal and clinical application of Manzardo C, Esteve A, Ortega N, et al. Optimal timing for initiation of highly active antiretroviral therapy in treatment-naïve human immunodeficiency virus-1-infected individuals presenting with AIDS-defining diseases: the experience of the PISCIS Cohort. Clin. Microbiol. Infect. 2013 July;19(7):646-653. doi: 10.1111/j.1469-0691.2012.03991.x


Pharmacologic Diuresis Is Safer Than Ultrafiltration For Cardiorenal Syndrome, Grace Choong Aug 2016

Pharmacologic Diuresis Is Safer Than Ultrafiltration For Cardiorenal Syndrome, Grace Choong

Clinical Research in Practice: The Journal of Team Hippocrates

A critical appraisal and clinical application of Bart BA, Goldsmith SR, Lee KL et al. Ultrafiltration in decompensated heart failure with cardiorenal syndrome. N Engl J Med. 2012;367:2296-2304. doi: 10.1056/NEJMoa1210357


Spinal Compression Fractures: No Additional Pain Relief With Use Of Back Braces, Kayla A. Berigan, Brandon Baker, Zakaria Ahmad, Aaron Simpson Aug 2016

Spinal Compression Fractures: No Additional Pain Relief With Use Of Back Braces, Kayla A. Berigan, Brandon Baker, Zakaria Ahmad, Aaron Simpson

Clinical Research in Practice: The Journal of Team Hippocrates

A critical appraisal and clinical application of Li M, Law SW, Cheng J, Kee HM, Wong MS. A comparison study on the efficacy of SpinoMed® and soft lumbar orthosis for osteoporotic vertebral fracture. J. Prosthet. Orthot. Int. 2015;39(4):270-276. doi: 10.1177/0309364614528204


Anticoagulation Following Gastrointestinal Bleeding: Assessing Harms And Benefits, Jacob Jeffers Aug 2016

Anticoagulation Following Gastrointestinal Bleeding: Assessing Harms And Benefits, Jacob Jeffers

Clinical Research in Practice: The Journal of Team Hippocrates

A critical appraisal and clinical application of Sengupta N, Feuerstein JD, Patwardhan VR, et al. The risks of thromboembolism vs. recurrent gastrointestinal bleeding after interruption of systemic anticoagulation in hospitalized in patients with gastrointestinal bleeding: a prospective study. Am. J. Gastroenterol. 2014;110:328-335. doi: 10.1038/ajg.2014.398


Restriction Therapy In Acute Heart Failure Is Not Shown To Be Effective, Amrit K. Basi, Colleen W. Harkreader, Nicholus H. Yee M.D., Shadia A. Yeihey M.D., Suraiya K. Azom M.D. Jul 2016

Restriction Therapy In Acute Heart Failure Is Not Shown To Be Effective, Amrit K. Basi, Colleen W. Harkreader, Nicholus H. Yee M.D., Shadia A. Yeihey M.D., Suraiya K. Azom M.D.

Clinical Research in Practice: The Journal of Team Hippocrates

A critical appraisal and clinical application of Travers B, O’Loughlin C, Murphy NF, et al. Fluid restriction in the management of decompensated heart failure: no impact on time to clinical stability. J Card Fail. 2007;13(2):128-132. doi: 10.1016/j.cardfail.2006.10.012


Vedolizumab Should Be The Next Line Agent For The Treatment Of Refractory Crohn’S Disease, Mitchell Kentor Jul 2016

Vedolizumab Should Be The Next Line Agent For The Treatment Of Refractory Crohn’S Disease, Mitchell Kentor

Clinical Research in Practice: The Journal of Team Hippocrates

A critical appraisal and clinical application of Shelton E, Allegretti J, Stevens B et al. Efficacy of Vedolizumab as Induction Therapy in Refractory IBD Patients. Inflammatory Bowel Diseases. 2015 Dec;21(12):2879-2885. doi:10.1097/mib.0000000000000561


Statin Therapy For Elderly Patients Should Be Assessed For Each Individual, Raymond Gong Jul 2016

Statin Therapy For Elderly Patients Should Be Assessed For Each Individual, Raymond Gong

Clinical Research in Practice: The Journal of Team Hippocrates

A critical appraisal and clinical application of Shepherd J, Blauw GJ, Murphy MB, et al. Pravastatin in elderly individuals at risk of vascular disease (PROSPER): a randomised controlled trial. Lancet. 2002;360(9346):1623-30. doi:10.1016/S0140-6736(02)11600-X


It Is Reasonable To Treat Patients With Type 1 Hepatorenal Syndrome With Midodrine And Octreotide, William Kane Jul 2016

It Is Reasonable To Treat Patients With Type 1 Hepatorenal Syndrome With Midodrine And Octreotide, William Kane

Clinical Research in Practice: The Journal of Team Hippocrates

A critical appraisal and clinical application of Esrailian E, Pantangco ER, Kyulo NL, Hu KQ, Runyon BA. Octreotide/midodrine therapy significantly improves renal function and 30-day survival in patients with type 1 hepatorenal syndrome. Dig Dis Sci. 2007;52(3):742-748. doi: 10.1007/s10620-006-9312-0


Salvage Therapy For Non-Acetaminophen-Induced Acute Liver Failure Includes N-Acetylcysteine, David Robinson Jul 2016

Salvage Therapy For Non-Acetaminophen-Induced Acute Liver Failure Includes N-Acetylcysteine, David Robinson

Clinical Research in Practice: The Journal of Team Hippocrates

A critical appraisal and clinical application of Lee WM, Hynan LS, Rossaro L, et al. Intravenous N-acetylcysteine improves transplant-free survival in early stage non-acetaminophen acute liver failure. Gastroenterology. 2009;137(3):856-864. doi: 10.1053/j.gastro.2009.06.006


From The Editors, Thomas C. Bolig, William Kane, Mitchell Kentor Jul 2016

From The Editors, Thomas C. Bolig, William Kane, Mitchell Kentor

Clinical Research in Practice: The Journal of Team Hippocrates

Introduction to Volume 2, Issue 2 by the new Senior Student Editors.


Guidelines Are Not Evidence, James P. Meza Md, Phd, Nicholus H. Yee Md Jun 2016

Guidelines Are Not Evidence, James P. Meza Md, Phd, Nicholus H. Yee Md

Clinical Research in Practice: The Journal of Team Hippocrates

Guidelines are inherently flawed when caring for an individual patient, because they apply to populations, not individuals. A strong competency in reading and interpreting clinical research gives doctors the power to evaluate guidelines and make appropriate shared decisions with their patients.


Glucocorticoids Do Not Decrease Mortality In Severe Alcoholic Hepatitis, Thomas C. Bolig Jun 2016

Glucocorticoids Do Not Decrease Mortality In Severe Alcoholic Hepatitis, Thomas C. Bolig

Clinical Research in Practice: The Journal of Team Hippocrates

A critical appraisal and clinical application of Thursz MR, Richardson P, Allison M, et al. Prednisolone or pentoxifylline for alcoholic hepatitis. N Engl J Med. 2015;372(17):1619-28. doi: 10.1056/NEJMoa1412278


There Is Relief For Constipated Patients Taking Opioids., Ahmad Mohammadieh, James Choi, Md, Chelsea Gonzalez, Do, Diyanah Elyaman, Md May 2016

There Is Relief For Constipated Patients Taking Opioids., Ahmad Mohammadieh, James Choi, Md, Chelsea Gonzalez, Do, Diyanah Elyaman, Md

Clinical Research in Practice: The Journal of Team Hippocrates

A critical appraisal and clinical application of Tack J, Lappalainen J, Diva U, Tummala R, Sostek M. Efficacy and safety of naloxegol in patients with opioid-induced constipation and laxative-inadequate response. United European Gastroenterol J. 2015 Oct;3(5):471-80. doi: 10.1177/2050640615604543


Carotid Ultrasound Is Not Helpful In Simple Syncope, Nicholus Yee M.D., Shilin Patel M.D., Raymond Gong May 2016

Carotid Ultrasound Is Not Helpful In Simple Syncope, Nicholus Yee M.D., Shilin Patel M.D., Raymond Gong

Clinical Research in Practice: The Journal of Team Hippocrates

A critical appraisal and clinical application of Scott JW, Schwartz AL, Gates JD, Gerhard-Herman M, Havens JM. Choosing wisely for syncope: low-value carotid ultrasound use. J Am Heart Assoc. 2014 Aug 13;3(4). pii: e001063. doi: 10.1161/JAHA.114.001063


Advocating For Our Patients Using Clinical Research, Brandon Baker Apr 2016

Advocating For Our Patients Using Clinical Research, Brandon Baker

Clinical Research in Practice: The Journal of Team Hippocrates

This reflection is about experiences trying to relate medical research evidence to actual patient care. This piece talks about shared decision-making about screening mammography.


Splenic Biopsies Are Underutilized Due To Overestimation Of Bleeding Risks, Nicholas Destefano Apr 2016

Splenic Biopsies Are Underutilized Due To Overestimation Of Bleeding Risks, Nicholas Destefano

Clinical Research in Practice: The Journal of Team Hippocrates

A critical appraisal and clinical application of Civardi G, Vallisa D, Berte R, et al. Ultrasound-guided fine needle biopsy of the spleen: high clinical efficacy and low risk in a multicenter Italian study. Am J Hematol. 2001 Jun;67(2):93-9. doi:10.1002/ajh.1085


Abnormal Uterine Bleeding Guidelines And Clinical Practice Are Based On Poor Quality Evidence, Mirek Mychajlowycz Feb 2016

Abnormal Uterine Bleeding Guidelines And Clinical Practice Are Based On Poor Quality Evidence, Mirek Mychajlowycz

Clinical Research in Practice: The Journal of Team Hippocrates

A critical appraisal and clinical application of Munro MG, Mainor N, Basu R, Brisinger M, Barreda L. Oral medroxyprogesterone acetate and combination oral contraceptives for acute uterine bleeding: A randomized controlled trial. Obstet Gynecol. 2006 Oct;108(4):924-929. doi:10.1097/01.AOG.0000238343.62063.22


Induced Hypothermia Post Cardiac Resuscitation Works In Hospitalized Patients But Not During Transport To Hospital, A Logical Inconsistency Of Evidence, Joshua Frederick Feb 2016

Induced Hypothermia Post Cardiac Resuscitation Works In Hospitalized Patients But Not During Transport To Hospital, A Logical Inconsistency Of Evidence, Joshua Frederick

Clinical Research in Practice: The Journal of Team Hippocrates

A critical appraisal and clinical application of Kim F, Nichol G, Maynard C, et al. Effect of prehospital induction of mild hypothermia on survival and neurological status among adults with cardiac arrest. JAMA 2013;311(1):45-52. doi:10.1001/jama.2013.282173


Defining Quality In Medical Practice, Nicholas E. Boggs Feb 2016

Defining Quality In Medical Practice, Nicholas E. Boggs

Clinical Research in Practice: The Journal of Team Hippocrates

We need physicians who are willing to participate in creating the standard of care, and to hold insurance companies accountable for real evidence-based quality markers. Only then will patients receive adequate care and we as educators in medicine be able to adequately teach the next generation of physicians.


From The Editors, John Dawdy, J. Timothy Caldwell Feb 2016

From The Editors, John Dawdy, J. Timothy Caldwell

Clinical Research in Practice: The Journal of Team Hippocrates

Editorial introduction to the third issue of Clinical Research in Practice: The Journal of Team Hippocrates.