Mental Disorders Commons^™

Research Brief: "Psychopathology, Iraq And Afghanistan Service, And Suicide Among Veterans Health Administration Patients", Institute For Veterans And Military Families At Syracuse University

Institute for Veterans and Military Families

This brief is about the connections between being a OIF/OEF veteran who receives care from the VHA and suicide mortality. In policy and practice, mental health screenings for OIF/OEF veterans should be implemented in non-VHA healthcare settings and families of OIF/OEF veterans should encourage veterans to seek treatment if they exhibit signs of a mental health condition. The VHA should implement policies that promote its healthcare to veterans in order to decrease suicide risks among veterans and should also offer more mental health screenings for recently returned veterans. Suggestions for future research include looking at risks for suicide after traumatic …

Septohippocampal Gabaergic Neurons Mediate The Altered Behaviors Induced By N-Methyl-D-Aspartate Receptor Antagonists., Jingyi Ma, Siew Kian Tai, L Stan Leung

Physiology and Pharmacology Publications

We hypothesize that selective lesion of the septohippocampal GABAergic neurons suppresses the altered behaviors induced by an N-methyl-D-aspartate (NMDA) receptor antagonist, ketamine or MK-801. In addition, we hypothesize that septohippocampal GABAergic neurons generate an atropine-resistant theta rhythm that coexists with an atropine-sensitive theta rhythm in the hippocampus. Infusion of orexin-saporin (ore-SAP) into the medial septal area decreased parvalbumin-immunoreactive (GABAergic) neurons by ~80%, without significantly affecting choline-acetyltransferase-immunoreactive (cholinergic) neurons. The theta rhythm during walking, or the immobility-associated theta induced by pilocarpine, was not different between ore-SAP and sham-lesion rats. Walking theta was, however, more disrupted by atropine sulfate in ore-SAP than …

Sexual Reward And Depression, Andrea R. Di Sebastiano

Electronic Thesis and Dissertation Repository

Sexual behavior in male rats is a complex rewarding behavior and many neurotransmitters and neuropeptides play an important role in mediation of sexual performance, motivation and reward. The hypothalamic neuropeptide orexin has been shown play a key role in reward associated with food and drugs of abuse, but the role of this neuropeptide in control of sexual performance, motivation and reward is currently unclear. First, it was shown that orexin neurons in the hypothalamus are activated during sexual performance and reward. Next, using cell specific lesions of orexin neurons it was demonstrated that orexin is involved in arousal and anxiety, …

Research Brief: "Impact Of The Seeking Safety Program On Clinical Outcomes Among Homeless Female Veterans With Psychiatric Disorders", Institute For Veterans And Military Families At Syracuse University

Institute for Veterans and Military Families

This brief is about the effect of the Seeking Safety program's services on improvement in PTSD, psychiatric symptoms, and social support among homeless female veterans. In policy and practice, clinicians should be trained on how to use the program to better serve homeless female veterans, and policymakers should push for clinician training for those who work with homeless veterans. Suggestions for future research include applying this study and the Seeking Safety program to non-VA healthcare systems, assessing substance use within the program, and assessing the long-term effects of the Seeking Safety program.

Research Brief: "Web-Based Post-Traumatic Stress Disorder Education For Military Family Members", Institute For Veterans And Military Families At Syracuse University

Institute for Veterans and Military Families

In this study, researchers introduced an educational website to assess and improve knowledge of PTSD, and also help to engage family members in positive actions to assist service members struggling with PTSD. Web-based content can serve as a valuable method of providing care and information to military service members without the risk of being stigmatized; therefore, policy makers should focus on creating and maintaining structural and financial support for programs that provide military service members, and their families, tools to manage post-deployment issues. Future studies should focus on providing an increased range of services for military families using the educational …

Understanding The Functionality Of Depression Among Australian Breast Cancer Patients: Implications For Cognitive And Behavioural Interventions, Christopher Sharpley, Vicki Bitsika, David Christie

Vicki Bitsika

Background: Depression in breast cancer (BCa) patients can reduce quality of life, relationships and treatment compliance, thus constituting a major target for cognitive behavioural (CBT) interventions. Although CBT treatments, which are built upon consideration of the roles of antecedents and consequences for depressive behaviour, are effective, the nature of those antecedents which trigger depression among BCa patients has received relatively little attention.

Purpose: Hypotheses were (1) to determine if BCa patients were experiencing either or both of punishment type I and II and (2) to identify if these aspects of punishment were related to overall depression.

Method: Two hundred fifty-three …

How Is Resilience Associated With Anxiety And Depression? Analysis Of Factor Score Interactions Within A Homogeneous Sample, Vicki Bitsika, Christopher Sharpley, Kylie Peters

Vicki Bitsika

Aim: To explore the ways in which resilience is associated with anxiety and depression within a homogenous sample.Methods: 401 Australian university students completed the Connor-Davidson Resilience Scale and the Zung SelfratingAnxiety and Depression Scales. Factor scores from the resilience scale were regressed against total anxiety and depression scores, combined anxiety-depression scores and the underlying factors of the combined anxiety-depression construct.Results: Self-confidence and optimism were most strongly negatively associated with anxiety and depression, followed by being decisive and solution-focussed and seeking challenges, having a strong purpose and being persistent, although different combinations of factors predicted anxiety than did depression. Spiritual beliefs …

Impact Of Sunlight On The Age Of Onset Of Bipolar Disorder, Michael Bauer, Tasha Glenn, Martin Alda, Ole A. Andreassen, Raffaella Ardau, Frank Bellivier, Michael Berk, Thomas D. Bjella, Letizia Bossini, Maria Del Zompo, Seetal Dodd, Andrea Fagiolini, Mark A. Frye, Ana Gonzalez-Pinto, Chantal Henry, Flávio Kapczinkski, Sebastian Kliwicki, Barbara König, Mauricio Kunz, Beny Lafer, Carlos Lopez-Jaramillo, Mirko Manchia, Wendy Marsh, Monica Martinez-Cengotitabengoa, Ingrid Melle, Gunnar Morken, Rodrigo Munoz, Fabiano G. Nery, Claire O'Donovan, Andrea Pfennig, Danilo Quiroz, Natalie Rasgon, Andreas Reif, Janusz Rybakowski, Kemal Sagduyu, Christian Simhandi, Carla Torrent, Eduard Vieta, Mark Zetin, Peter C. Whybrow

Marriage and Family Therapy Faculty Articles and Research

Objective: Although bipolar disorder has high heritability, the onset occurs during several decades of life, suggesting that social and environmental factors may have considerable influence on disease onset. This study examined the association between the age of onset and sunlight at the location of onset.

Method: Data were obtained from 2414 patients with a diagnosis of bipolar I disorder, according to DSM-IV criteria. Data were collected at 24 sites in 13 countries spanning latitudes 6.3 to 63.4 degrees from the equator, including data from both hemispheres. The age of onset and location of onset were obtained retrospectively, from …

Characteristics, Management, And Depression Outcomes Of Primary Care Patients Who Endorse Thoughts Of Death Or Suicide On The Phq-9, Amy M. Bauer, Ya-Fen Chan, Hsiang Huang, Steven D. Vannoy, Jurgen Unuzter

Steven D Vannoy

BACKGROUND: With increasing emphasis on integrat- ing behavioral health services, primary care providers play an important role in managing patients with suicidal thoughts. OBJECTIVE: To evaluate whether Patient Health Questionnaire-9 (PHQ-9) Item 9 scores are associated with patient characteristics, management, and depres- sion outcomes in a primary care-based mental health program. DESIGN: Observational analysis of data collected from a patient registry. PARTICIPANTS: Eleven thousand fifteen adults en- rolled in the Mental Health Integration Program (MHIP). INTERVENTIONS: MHIP provides integrated mental health services for safety-net populations in over 100 community health centers across Washington State. Key elements of the team-based model …

Taking The Perspective That A Depressive State Reflects Inflammation: Implications For The Use Of Antidepressants, Jill Littrell

SW Publications

This paper reviews both the evidence that supports the characterization of depression as an inflammatory disorder and the different biochemical mechanisms that have been postulated for the connection between inflammation and depression. This association offers credible explanation for the short term efficacy of antidepressants, which have short term anti-inflammatory effects. Evidence for those anti-inflammatory effects is discussed. Evidence of the contrary long-term effects of antidepressants, which increase rather than decrease inflammation, is also reviewed. It is argued that this increase in inflammation would predict an increase in chronicity among depressed patients that have been treated with antidepressants drugs, which has …

Opinion: Bias Is Unavoidable, Lisa Cosgrove

Counseling and School Psychology Faculty Publication Series

It is part of the human condition to have implicit biases—and remain blissfully ignorant of them. Academic researchers, scientists, and clinicians are no exception; they are as marvelously flawed as everyone else. But it is not the cognitive bias that’s the problem. Rather, the denial that there is a problem is where the issues arise. Indeed, our capacity for self-deception was beautifully captured in the title of a recent book addressing researchers’ self-justificatory strategies, Mistakes Were Made (But Not by Me).

Affect Identification And Interpersonal Skills: An In-Depth Evaluation Of Social Cognition In Schizophrenia, Griffin Pollock Sutton

UNLV Theses, Dissertations, Professional Papers, and Capstones

The presence of deficits in various sub-domains of social cognition has been investigated to a degree in individuals with schizophrenia. Some of the most commonly researched and documented deficits have included impairments in the identification of affect portrayed in faces. Research has indicated that the performance of individuals with schizophrenia on such tasks is generally impaired as compared to normal controls. However, some have questioned the generalizability of such findings to real-world situations, as day-to-day interactions generally necessitate a constant, fluid assessment of the thoughts and feelings of others and are rarely, if ever, limited to still images of others. …

Research Brief: "Civilian Employment Among Recently Returning Afghanistan And Iraq National Guard Veterans", Institute For Veterans And Military Families At Syracuse University

Institute for Veterans and Military Families

This brief shows the impact of OIF and OEF National Guard and Reserve veterans' mental health problems on their likelihood of employment. This study, unusually, found that less than half of the surveyed National Guard and Reserve service members had obtained employment by 45-60 days post-mobilization, despite their possible mental health problems. Suggestions for future research include gathering information from all potential survey participants, as well as service members entering the civilian workforce, beyond the first 45-60 days post-deactivation, rather than within this period.

Primary Care Behavioral Health Consultation Reduces Depression Levels Among Mood-Disordered Patients, Bill Mcfeature, Thomas W. Pierce

Journal of Health Disparities Research and Practice

The purpose of this study was to examine the effects of behavioral health consultative services on levels of depressive symptoms in patients diagnosed with a mood disorder. Two-hundred fifty-one patients with a form of mood disorder completed the PHQ-9 screening tool for depression both before and after a treatment period lasting an average of three months, during which patients received behavioral health consultation services. Results showed that 49.8% of patients participating in this integrated behavioral health care program experienced improvements of at least 50% in PHQ-9 scores from pre- to post-test. Improvements in PHQ-9 scores of at least a five …

Prospective Investigation Of A Ptsd Personality Typology Among Individuals With Personality Disorders, Meghan E. Mcdevitt-Murphy, M. Tracie Shea, Shirley Yen, Carlos M. Grilo, Charles A. Sanislow, John C. Markowitz, Andrew E. Skodol

Charles A. Sanislow, Ph.D.

This study investigated the replicability of a previously proposed personality typology of posttraumatic stress disorder (PTSD, and explored stability of cluster membership over a 6-month period. Participants with current PTSD (n = 156) were drawn from the Collaborative Longitudinal Personality Disorders Study (CLPS). The CLPS project tracked a large sample of individuals who met criteria for 1 of 4 target diagnoses (borderline, schizotypal, avoidant, and obsessive-compulsive) and a contrast group of individuals who met criteria for depression but no personality disorder. A cluster analysis using scales from the Schedule of Nonadaptive and Adaptive Personality yielded 3 clusters: “internalizing,” “externalizing,” and …

Research Brief: "Psychiatric Status And Work Performance Of Veterans Of Operations Enduring Freedom And Iraqi Freedom", Institute For Veterans And Military Families At Syracuse University

Institute for Veterans and Military Families

This study examines the relationship between psychiatric status and work impairment among OEF/OIF veterans enrolled in VA healthcare. In practice, mental health services are a high priority for the Veterans Administration, which is now focused on integrating behavioral health services into primary care so OEF/OIF veterans face fewer obstacles in obtaining and sustaining psychiatric care. In policy, policymakers should integrate veterans’ health programs with systematic assessment functioning, and develop treatment geared towards addressing impaired job performance. Suggestions for future study include focusing on whether workers with depression and other psychiatric conditions participate fully in the labor market and function effectively …

The Prevalence And Characteristics Of Suicidality In Hiv/Aids As Seen In An African Population In Entebbe District, Uganda, Eugene Kinyanda, Susan Hoskins, Juliet Nakku, Saira Nawaz, Vikram Patel

Dartmouth Scholarship

Suicidality in HIV/AIDS is not only a predictor of future attempted suicide and completed suicide, it is also associated with poor quality of life and poor adherence with antiretroviral therapy. This paper examines the prevalence and correlates of suicidality in HIV/AIDS in the African nation of Uganda.

Help-Negation For Suicidal Thoughts In Sub-Clinical Samples Of Young People, Coralie Joy Wilson

Coralie J Wilson

Across the popular and academic literature, it is widely recognised that young people with persistent suicidal thoughts are at high risk for suicide completion. It is also accepted that seeking and receiving appropriate help offers protection against the development of acute forms of suicidality, along with suicide completion. Yet, as promising as appropriate help-seeking appears for suicide prevention, a growing number of studies suggest that suicidal ideation itself may impede the help-seeking process. There is evidence that acutely suicidal samples will negate or avoid available help, and there are indications that the help-negation process may occur in samples before levels …

Research Brief: "Employment Outcomes And Ptsd Symptom Severity", Institute For Veterans And Military Families At Syracuse University

Institute for Veterans and Military Families

This study investigates how the severity of PTSD symptoms relates to employment and earnings. It found that veterans with more severe symptoms of PTSD were more likely to work part-time or not at all rather than have full-time work. In practice, treating PTSD, even if some symptoms remain, could result in better employment outcomes for veterans. In policy, policymakers should consider providing previously successful programs focused on veterans with PTSD for individuals with other mental health conditions. Suggestions for future research include a large, controlled, longitudinal survey that would allow researchers to investigate more thoroughly how PTSD symptoms relate to …

Medical Oxymoron Or Necessary Prevention Of Repeat Sex Offenses: An Examination Of The Appropriateness Of Existing Chemical Castration Statutes, Robert Watters

Robert Watters

The current chemical castration statutes in six states are full of logical constitutional, medical and ethical questions and concerns. The basis for the criticism can be traced to how the schemes were developed compared to the those used in Europe. The castration statutes enacted after long trial and error periods are, therefore, easily discernible from those signed into law quickly as a reaction to some outside event.

Predictors Of Depression For Low-Income African American Single Mothers, Jennifer Hatcher, Mary K. Rayens, Ann R. Peden, Lynne A. Hall

Journal of Health Disparities Research and Practice

Purpose: To test a model of predictors of depression in low-income single African American mothers. Design: Secondary analysis of existing data collected as part of a study of women at risk for clinical depression.

Methods: Cross sectional secondary data analysis of a study of low-income African American single mothers with children ages 2-6. Path analysis was used to test a model of the potential mediating role of negative thinking. It was hypothesized that negative thinking mediates the effects of chronic stressors, general health status, and self-esteem on depressive symptoms

Finding: Negative thinking mediated the relationships of chronic stressors and self-esteem …

Housing And Housing Services Program Measure – Veterans Version (Hhspm-V), Colleen Clark, M. Scott Young, Sarah R. Moody, Gregory Teague, Rhonda Ort, James Winarski, Kathleen Moore, Minnie Norton, Blake Barrett

Mental Health Law & Policy Faculty Publications

No abstract provided.

The Delivery System Design Of A Community Mental Health Center And Provision Of Quality: Cardiometabolic Screening For Persons With A Severe Mental Illness Prescribed Atypical Antipsychotic Medication, Dawn Marie Vanderhoef

Theses and Dissertations (ETD)

Background: Persons with a severe mental illness (SMI) prematurely lose up to 25 years of life when compared to the general population. This patient population has increased morbidity and mortality due to higher than normal rates of obesity, hypertension, diabetes, and cardiovascular disease. Treatment of SMI often includes the use of atypical antipsychotic (AA) medication which has been associated with the development of cardiometabolic illnesses. In response to the higher rates of co-morbid, chronic physical illness, monitoring guidelines for cardiometabolic illness have been published. Despite these guidelines, screening rates for cardiometabolic illness in this population remain low. Neither community mental …

Using Negative Feedback To Guide Behavior: Impairments On The Wisconsin Card Sorting Test Relates To Psychosis, Sally Barney

UNLV Theses, Dissertations, Professional Papers, and Capstones

There is increasing controversy regarding the distinction between schizophrenia and bipolar disorder as separate diagnostic categories because these disorders share many features in common. These and other findings suggest that bipolar disorder and schizophrenia may be better conceptualized along a continuum or within more homogeneous subsets of affective, psychotic, and mixed symptomatology.

Dopamine dysregulation has been found in schizophrenia and bipolar disorder, particularly those that experience psychosis during the acute phases of their bipolar illness. Dopamine has been found to play a role in reward and reward learning. Recently, research has found that individuals with schizophrenia experience deficits in reward …

Teaching Language To Children With Developmental Disabilities Using Combined Direct Reinforcement And Stimulus-Stimulus Pairing, Brighid Helene Fronapfel-Sonderegger

Dissertations

Several researchers have used stimulus-stimulus pairing (the pairing of speech sounds with established reinforcers) to increase the frequency of specific vocalizations in children with disabilities. However, only a few addressed the utility of stimulus-stimulus pairing to increase functional language, and none combined stimulus-stimulus pairing and direct reinforcement. The present study combined stimulus-stimulus pairing and direct reinforcement to successfully teach 2 to 10 functional mands in 21–49 7-minute sessions with four children with developmental disabilities with low verbal repertoires. Following mand training, two children were taught 10 tacts for pictures using the combined direct reinforcement and stimulus-stimulus pairing procedure in a …

Stereological Assessment Of The Thalamus In A Rat Model Of Periventricular Nodular Heterotopia, Jason Lennox

Honors Projects

Malformations of neocortical development such as microgyria (MG) and periventricular nodular heterotopia (PNH) have been observed in the brains of language learning impaired (LLI) humans. Rats with MG have shown rapid auditory processing (RAP) deficits similar to acoustic deficits observed in some human LLI populations. Threlkeld et al., (2009) previously reported RAP and other learning impairments in rats with PNH resulting from disruption to embryonic neuronal cell division by way of Methylazoxymethanol (MAM) treatment on embryonic day 15 (E15). The thalamus and its subnuclei may be vulnerable to neurodevelopmental disruptions. Studies of MG rats have shown changes in cell size …

Avoidant Personality Disorder, Traits, And Type, Charles A. Sanislow, Katelin Da Cruz, May O. Gianoli, Elizabeth M. Reagan

Charles A. Sanislow, Ph.D.

In this chapter, the evolution of the avoidant personality disorder (AVPD) diagnosis, its current status, and future possibilities are reviewed. AVPD is a chronic and enduring condition involving a poor sense of self and anxiety in social situations, and it is marked by fears of rejection and a distant interpersonal stance. AVPD may be conceptualized at the severe end of a continuum of social anxiety. In the extreme, traits, mechanisms, and symptoms become integral to chronic dysfunction in personality and interpersonal style. While AVPD is a valid diagnostic construct, the optimal organization of AVPD criteria for the diagnosis, and the …

The American Psychiatric Association’S Guideline For Major Depressive Disorder: A Commentary, Lisa Cosgrove, Allen F. Shaughnessy, Emily E. Wheeler, Kirsten E. Austad, Irving Kirsch, Harold J. Bursztajn

Counseling and School Psychology Faculty Publication Series

The American Psychiatric Association (APA) published a new guideline for Major Depressive Disorder (MDD) which will undoubtedly be used by many practitioners to guide clinical decision-making. In fact, it is non-psychiatrist clinicians who prescribe the majority of antidepressants (AD). We review the APA’s most recent guideline on MDD and report on our observations.

A Comparison Of Dsm-Iv And Dsm-5 Panel Members’ Financial Associations With Industry: A Pernicious Problem Persists, Lisa Cosgrove, Sheldon Krimsky

Counseling and School Psychology Faculty Publication Series

All medical subspecialties have been subject to increased scrutiny about the ways by which their financial associations with industry, such as pharmaceutical companies, may influence, or give the appearance of influencing, recommendations in review articles and clinical practice guidelines. Psychiatry has been at the epicenter of these concerns, in part because of high-profile cases involving ghostwriting and failure to report industry-related income, and studies highlighting conflicts of interest in promoting psychotropic drugs. The revised Diagnostic and Statistical Manual of Mental Disorders (DSM), scheduled for publication in May 2013 by the American Psychiatric Association (APA), has created a firestorm of controversy …

Bungy Jump Into The Unknown - Women Escaping Domestic Violence, Megan Levy

Megan Levy

What happens to those women coming out of a women’s refuge? Can they live away from Domestic Violence? Do they have parenting skills? To answer these questions a case study methodology combined with theories from Humanistic, Social and Community Psychology was implemented to analyse the contents of the meetings held by the refuge’s Self-Help Group,. This group consisted of 11 women, ages 29 to 48 yo: Five of them still in domestic violence; and the rest escaping DV: two, in the refuge, and four who had left 12 to 36 months ago. The first finding: When a woman is still …