Mental Disorders Commons^™

Ethnicity And Mental Health Treatment Utilization By Patients With Personality Disorders, Donna S. Bender, Andrew E. Skodol, Ingrid R. Dyck, John C. Markowitz, M. Tracie Shea, Shirley Yen, Charles A. Sanislow, Anthony Pinto, Mary C. Zanarini, Thomas H. Mcglashan, John G. Gunderson, Maria T. Daversa, Carlos M. Grilo

Charles A. Sanislow, Ph.D.

The authors examined the relationship between ethnicity and treatment utilization by individuals with personality disorders (PDs). Lifetime and prospectively determined rates and amounts of mental health treatments received were compared in over 500 White, African American, and Hispanic participants with PDs in a naturalistic longitudinal study. Minority, especially Hispanic, participants were significantly less likely than White participants to receive a range of outpatient and inpatient psychosocial treatments and psychotropic medications. This pattern was especially pronounced for minority participants with more severe PDs. A positive support alliance factor significantly predicted the amount of individual psychotherapy used by African American and Hispanic …

The Effects Of Nicotine Conditioned Place Preference In D2 Primed Adolescent Rats: Age-Related And Gender Effects., Yoko Emily Ogawa

Electronic Theses and Dissertations

This study investigated nicotine conditioned place preference (CPP) in two different ages of adolescence using a rodent model of schizophrenia. Both 2- and 3-chambered CPP apparatuses were used to test whether the CPP was due to an aversion to the white chamber. Animals were neontally treated with the dopamine D₂/D₃ agonist, quinpirole, or saline and raised to either early postweanling age (P 22) or adolescence (P 29). Rats were conditioned to prefer the white chamber using nicotine. Results showed that nicotine induced CPP and appeared to alleviate an increased stress response in D₂ primed animals, which …

Posttraumatic And Parent Stress In Parents Of Infant Heart Transplant Recipients, Jessie Rose Stevens

Loma Linda University Electronic Theses, Dissertations & Projects

Heart transplantation during infancy is a life-threatening event, and when successful, the treatment is a life-long process and the potential for life-threatening consequences never ceases. As a result, parents can be impacted in many ways by this traumatic and demanding experience that begins with the initial diagnosis of their infant and continues into the long-term life course of these children. This life-long process has the potential to cause symptoms of posttraumatic stress disorder as well as elevated levels of stress in parents. This study examined parental self-reported post-traumatic stress symptoms and parental stress in parents of children who received a …

Effects Of Distress On Health Care Utilization In Cancer Survivors (Nhis 2004), Natalie Christine Kaiser

Loma Linda University Electronic Theses, Dissertations & Projects

Distress rates have been found to be around 43%, as indicated by a study of five comprehensive cancer centers and as measured by the Distress Thermometer (Jacobsen, et ah, 2005). Furthermore, few studies have examined the current health care utilization among cancer patients as predicted by distress. Thus, population-based data from the NHIS (2004) was analyzed using SUDAAN software 1) to ascertain the current levels of distress as measured by the Kessler 6 scale experienced by cancer survivors based upon demographic characteristics, family structure, physical comorbitities, and cancer-related variables, and 2) to determine whether distress rates reported among cancer survivors …

Comparison Of Alternative Models For Personality Disorders, Leslie C. Morey, Christopher J. Hopwood, John G. Gunderson, Andrew E. Skodol, M. Tracie Shea, Shirley Yen, Robert L. Stout, Mary C. Zanarini, Carlos M. Grilo, Charles A. Sanislow, Thomas H. Mcglashan

Charles A. Sanislow, Ph.D.

BACKGROUND: The categorical classification system for personality disorder (PD) has been frequently criticized and several alternative dimensional models have been proposed.

METHOD: Antecedent, concurrent and predictive markers of construct validity were examined for three models of PDs: the Five-Factor Model (FFM), the Schedule for Nonadaptive and Adaptive Personality (SNAP) model and the DSM-IV in the Collaborative Study of Personality Disorders (CLPS) sample.

RESULTS: All models showed substantial validity across a variety of marker variables over time. Dimensional models (including dimensionalized DSM-IV) consistently outperformed the conventional categorical diagnosis in predicting external variables, such as subsequent suicidal gestures and hospitalizations. FFM facets …

Positive Childhood Experiences: Resilience And Recovery From Personality Disorder In Early Adulthood, Andrew E. Skodol, Donna S. Bender, Maria E. Pagano, M. Tracie Shea, Shirley Yen, Charles A. Sanislow, Carlos M. Grilo, Maria T. Daversa, Robert L. Stout, Mary C. Zanarini, Thomas H. Mcglashan, John G. Gunderson

Charles A. Sanislow, Ph.D.

OBJECTIVE: Recent follow-along studies of personality disorders have shown significant improvement in psychopathology over time. The purpose of this study was to prospectively investigate the association between positive childhood experiences related to resiliency and remission from personality disorder.

METHOD: Five hundred twenty patients with DSM-IV-based semistructured interview diagnoses of schizotypal, borderline, avoidant, or obsessive-compulsive personality disorders were evaluated 6 times over 4 years between September 1996 and June 2002. Positive childhood experiences, including achievements, positive interpersonal relationships with others, and caretaker competencies, were measured using the Childhood Experiences Questionnaire-Revised. The effects of positive childhood experiences on clinically significant remission from …

Psychosocial Impairment And Treatment Utilization By Patients With Borderline Personality Disorder, Other Personality Disorders, Mood And Anxiety Disorders, And A Healthy Comparison Group, Emily B. Ansell, Charles A. Sanislow, Thomas H. Mcglashan, Carlos M. Grilo

Charles A. Sanislow, Ph.D.

This study compared psychosocial functioning and treatment utilization in 130 participants who were diagnosed with a borderline personality disorder (BPD), a non-BPD personality disorder (OPD), a mood and/or anxiety disorder (MAD), or had no current psychiatric diagnosis and served as a healthy comparison group. Diagnostic and Statistical Manual of Mental Disorders (4th Edition) diagnoses, psychosocial functioning, and treatment utilization were determined by using well-established semistructured research interviews conducted by trained doctoral-level clinicians. Analysis of variance revealed the most severe deficits in functioning characterized the BPD group across areas of global functioning with more moderate impairments in functioning occurring in OPD …

The Relations Of Pain, Religious Coping, And Depression In Fibromyalgia Patients, Derek O. Bacchus

Loma Linda University Electronic Theses, Dissertations & Projects

This study attempted to examine the relationship between Fibromyalgia Syndrome (FMS) pain, religious coping, and depression. The Fibromyalgia Impact Questionnaire (FIQ), Short-Form McGill Pain Questionnaire (SF-MPQ), RCOPE, and the Center for Epidemiologic Studies Depression Scale (CES-D) were used to assess these constructs in 50 participants. The sample was primarily middle aged and female, which is typical of the FMS population. This study used multiple regression to make assumptions about the causal progression of the variables. Study findings show that religious coping does not appear to significantly mediate the strong relationship between FMS pain and depression. This research served to uncover …

Longitudinal Diagnostic Efficiency Of Dsm-Iv Criteria For Borderline Personality Disorder: A 2-Year Prospective Study, Carlos M. Grilo, Charles A. Sanislow, Andrew E. Skodol, John G. Gunderson, Robert L. Stout, Donna S. Bender, Shirley Yen, M. Tracie Shea, Leslie C. Morey, Mary C. Zanarini, Thomas H. Mcglashan

Charles A. Sanislow, Ph.D.

OBJECTIVE: To examine the longitudinal diagnostic efficiency of the DSM-IV criteria for borderline personality disorder (BPD). METHODS: At baseline, we used semistructured diagnostic interviews to determine criteria and diagnoses; blinded assessments were performed 24 months later with 550 participants. Diagnostic efficiency indices (specifically, conditional probabilities, total predictive power, and kappa) were calculated for each criterion determined at baseline, with the independent BPD diagnosis at follow-up used as the standard. RESULTS: Longitudinal diagnostic efficiencies for the BPD criteria varied, with the criteria of suicidality or self-injury and unstable relationships demonstrating the most predictive utility. CONCLUSIONS: BPD criteria differ in their predictive …

An Analysis Of Nicotine Exacerbation Of Reductions In Ppi In A Rodent Model Of Schizophrenia., Amanda Marie Maple

Electronic Theses and Dissertations

Prepulse inhibition (PPI) is an operational measure of sensorimotor gating and is known to be reduced when the dopamine D² receptor is activated. We used a rodent model of psychosis in which increases in dopamine D_{2 receptor sensitivity are produced through neonatal quinpirole (a dopamine D2 / D3 agonist) treatment to rats. Rats were administered quinpirole (1mg/kg) or saline from postnatal day (P) 1-21. Rats were raised to adulthood and tested on PPI. Results showed that neonatal quinpirole treatment produced a significant reduction in PPI, and nicotine exacerbated this reduction. This reduction was partially blocked by …}

Nicotine Sensitization In A Rodent Model Of Schizophrenia: A Comparison Of Adolescents, Adults, And Neurotrophic Factors., Marla Kay Perna

Electronic Theses and Dissertations

The behavioral effects of nicotine on locomotor activity in a rodent model of psychosis were analyzed. This model is based on neonatal quinpriole treatment (a dopamine D2/D3 agonist) which causes increased D2 receptor sensitivity, a phenomenon known as D2 priming that is common in schizophrenia. D2-primed adolescent rats did not demonstrate nicotine-induced hypoactivity early in training, and males demonstrated more rapid sensitization to nicotine as compared to controls administered nicotine. D2-primed females administered nicotine demonstrated increased stereotypic behavior. D2-primed adult rats given nicotine demonstrated significantly more robust sensitization to nicotine than controls given nicotine. Brain-derived neurotrophic factor (BDNF) was analyzed …

Natural Course Of Bulimia Nervosa And Of Eating Disorder Not Otherwise Specified: 5-Year Prospective Study Of Remissions, Relapses, And The Effects Of Personality Disorder Psychopathology, Carlos M. Grilo, Maria E. Pagano, Andrew E. Skodol, Charles A. Sanislow, Thomas H. Mcglashan, John G. Gunderson, Robert L. Stout

Charles A. Sanislow, Ph.D.

OBJECTIVE: To examine prospectively the natural course of bulimia nervosa and eating disorder not otherwise specified (EDNOS) and to test for the effects of personality disorder psychopathology on remission and relapse.

METHOD: Subjects were 92 female patients with current bulimia nervosa (N = 23) or EDNOS (N = 69) at baseline enrollment in the Collaborative Longitudinal Personality Disorders Study. Axis I psychiatric disorders (including eating disorders) were assessed with the Structured Clinical Interview for DSM-IV Axis I Disorders-Patient Version, and personality disorders were assessed with the Diagnostic Interview for DSM-IV Personality Disorders (DIPD-IV). The course of eating disorders was assessed …

Binge Eating, Emotion Regulation, And Cognitive Resources, Jennifer A. Tucker

Loma Linda University Electronic Theses, Dissertations & Projects

Research has shown that individuals with binge eating disorder (BED) have difficulty coping with negative emotions, although no research to date has directly investigated emotion regulation and binge eating. In the current study individuals with varying amounts of BED characteristics were measured for accuracy on a computerized task involving attention and working memory. Subsequent to the task, participants were given three self-report measures: the Eating Disorder Examination Questionnaire (EDEQ-I; Fairbum & Celio, 2004), the Positive and Negative Affect Schedule (PANAS; Watson, Clark & Tellgen, 1988), and the Emotion Regulation Questionnaire (ERQ; Gross & John, 2003). It was hypothesized that in …

Personality Traits Predict Current And Future Functioning Comparably For Individuals With Major Depressive And Personality Disorders, Christopher J. Hopwood, Leslie C. Morey, M. Tracie Shea, Thomas H. Mcglashan, Charles A. Sanislow, Carlos M. Grilo, John G. Gunderson, Mary C. Zanarini, Andrew E. Skodol

Charles A. Sanislow, Ph.D.

Axes I and II were separated in DSM-III to encourage the consideration of the influence of both personality and psychopathology on patient behavior, on the assumption that an understanding of personality would increment syndromal diagnosis in treatment decisions. However, in practice the distinction between Axis I and Axis II is less clear. The current report investigates one aspect on which Axis I and Axis II might be expected to differ, that being the the significance of normative personality traits as an influence on functional status. In this study, the contribution of normative personality traits to functioning is presented for 2 …

The Saint Of Worcester: Why Pilgrims Visit Audrey Santo, Mathew N. Schmalz

Religious Studies Faculty Scholarship

No abstract provided.

Longitudinal Effects Of Personality Disorders On Psychosocial Functioning Of Patients With Major Depressive Disorder, John C. Markowitz, Andrew E. Skodol, Eva Petkova, Jianfeng Cheng, Charles A. Sanislow, Carlos M. Grilo, John G. Gunderson, Thomas H. Mcglashan

Charles A. Sanislow, Ph.D.

OBJECTIVE: No previous research has focused on psychosocial functioning in understanding how personality disorders compound the impairment caused by major depressive disorder over time. This report describes the effects of persistent and remitting comorbid personality disorders on the depressive status and functioning of patients with major depressive disorder over the course of 2 years.

METHOD: Longitudinal data on functioning from the first 2 years of the Collaborative Longitudinal Personality Disorders Study were evaluated for 3 groups of subjects with major depressive disorder: subjects with major depressive disorder alone (N = 103), those with persistent comorbid personality disorders (N = 164), …

Integrating Mental Health And Primary Care, Stephen Thielke, Steven D. Vannoy, JüRgen UnüTzer

Steven D Vannoy

No abstract provided.

Models Of Care For Treating Late-Life Depression In Primary Care, Steven D. Vannoy, Diane Powers, JüRgen UnüTzer

Steven D Vannoy

No abstract provided.

The Relationship Between Suicide Ideation And Late-Life Depression, Steven D. Vannoy, Paul Duberstein, Kelly Cukrowicz, Elizabeth Lin, Ming-Yu Fan, Ju ̈Rgen Unu ̈Tzer

Steven D Vannoy

Objective: To describe the course of suicide ideation (SI) in primary-care based late-life depression treatment, identify predictors of SI, characterize the dynamic relationship between depression and SI, and test the hypothesis that collaborative care decreases the likelihood of reporting SI by decreasing the severity of depressive symptoms. Methods: This was a secondary analysis of a randomized controlled trial comparing collaborative care to usual care for late-life depression. Participants were 1,801 adults age 60 and older from eight diverse primary-care systems. Depression was measured using the Hopkins Symptoms Checklist (HSCL-20). SI was operation- alized using one item from the HSCL-20. Predictors …

Practical Approaches To Treating Patients With Bipolar Disorder, Jane E. Neu, Susan M. Denisco

Nursing Faculty Publications

Many patients present to a primary care setting with symptoms of a mood disorder. These symptoms may be indicative of an anxiety disorder or a depressive disorder, but they may also represent bipolar disorder, which is more common than many practitioners think. Correctly diagnosing bipolar disorder can be complex, because patients tend to seek treatment when they are experiencing the symptoms of depression or anxiety rather than mania or hypomania. Comorbid disorders such as substance abuse and anxiety disorders may complicate the clinical presentation. Failing to correctly diagnose bipolar disorder can have serious consequences in terms of patients' morbidity and …

Abuse And Dissociation Disorder, Myrtle Godfrey

Graduate Research Papers

Child sexual abuse is widely regarded as a cause of mental problems in adult life. The damage inflicted by child sexual abuse.has an affect on the child's capacity to develop trust, intimacy and sexuality. Sexually abused children not only encounter assaults on their developing sense of sexual identity, but a blow to their interpretation of the world as a safe environment, and their developing sense of others as trustworthy. In addition, childhood sexual abuse is correlated with higher levels of dissociation. (Fleming, J. & Mullen, P. E., 1998). Of the victims that were abused by someone with whom he or …

Cutting Through The Confusion (Review), Kristina M. Kays

Faculty Publications - Psychology Department

Reviews the video, Self-Injury (with) Wendy Lader (2006). Self-injury behavior (SIB) includes, among other behaviors, "intentional carving or cutting of the skin and subdermal tissue, scratching, burning, ripping or pulling skin or hair, swallowing toxic substances, bruising, and breaking bones" (Cornell Research Program, 2006). Over the last two decades self-injury reports have risen noticeably because of increased SIB in adolescents, more clients seeking help, and increased reliability in diagnosis among professionals. The alarming numbers indicate a desperate need to understand how to diagnose and treat SIB clients effectively. In response to this escalating need, guest expert Wendy Lader is featured …

Ketamine-Enhanced Psychotherapy: Preliminary Clinical Observations On Its Effects In Treating Death Anxiety, Eli Kolp, M. Scott Young, Harris L. Friedman, Evgeny Krupitsky, Karl Jansen, Laurie-Ann O'Connor

Mental Health Law & Policy Faculty Publications

Ketamine, a dissociative anesthetic commonly used by US physicians, has recently been shown to be a powerful anti-depressant and is also capable of eliciting transpersonal experiences that can be transformative. Although currently approved in the US only for use as an anesthetic, physicians there can legally prescribe it off-label to treat various psychological/ psychiatric problems and it has been used for these non-anesthetic purposes in Argentina, Iran, Mexico, Russia, and the UK, as well as in the US. The literature on using ketamine psychotherapeutically is reviewed and two case studies using ketamine-enhanced psychotherapy (KEP) for treating death anxiety in terminally-ill …

Consent Or Coercion? Referral To Alcoholics Anonymous, Louis Charland

Louis C. Charland

No abstract provided.

Does Borderline Personality Disorder Exist?, Louis Charland

Louis C. Charland

No abstract provided.

Anorexia And The Maccat-T Test For Mental Competence: Validity, Value, Emotion. Commentary On Jacinta Tan’S Competence To Make Treatment Decisions In Anorexia Nervosa: Thinking Processes And Values, Louis Charland

Louis C. Charland

No abstract provided.

Affective Neuroscience And Addiction, Louis Charland

Louis C. Charland

No abstract provided.

Cognitive Modularity Of Emotion, Louis Charland

Louis C. Charland

No abstract provided.

Benevolent Theory: Moral Treatment At The York Retreat, Louis Charland

Louis C. Charland

No abstract provided.

Mental Health Parity Laws, Louis Graham, Kisha Braithwaite

Louis F Graham