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Full-Text Articles in Behavior and Behavior Mechanisms

Materials And Methods Developed For The Recording And Analysis Of Behavior In The Common Marmoset (Callithrix Jacchus)., Christian Wintle Mar 2024

Materials And Methods Developed For The Recording And Analysis Of Behavior In The Common Marmoset (Callithrix Jacchus)., Christian Wintle

UNO Student Research and Creative Activity Fair

Materials and methods developed for the recording and analysis of behavior in the common marmoset (Callithrix jacchus).

Christian J. Wintlea, Jordan B. Hernandeza,b,c, Dobromir Dotovd, and Jonathan B. Claytona,b,e,f,g

aDepartment of Biology, University of Nebraska at Omaha, Omaha, NE, USA

bNebraska Food for Health Center, University of Nebraska-Lincoln, Lincoln, NE, USA

cDepartment of Genetics, Cell Biology, and Anatomy, University of Nebraska Medical Center, NE, USA

dDepartment of Biomechanics, University of Nebraska at Omaha, Omaha, NE, USA

eDepartment of Food Science and Technology, University of Nebraska-Lincoln, Lincoln, …


Fornix Volumetric Increase During Aging Associates To Microglia Activation Leading To Defective Cognitive Performance, Marcela Cárdenas Tueme, Luis Ángel Trujillo-Villarreal, Victor Ramírez-Amaya, Eduardo Garza-Villarreal, Alberto Camacho-Morales, Diana Reséndez-Pérez Sep 2023

Fornix Volumetric Increase During Aging Associates To Microglia Activation Leading To Defective Cognitive Performance, Marcela Cárdenas Tueme, Luis Ángel Trujillo-Villarreal, Victor Ramírez-Amaya, Eduardo Garza-Villarreal, Alberto Camacho-Morales, Diana Reséndez-Pérez

Research Symposium

Background: Ageing displays a low-grade pro-inflammatory profile in blood and brain. It has been documented proinflammatory cytokines accumulation leading to neuroinflammation during aging. Aged brains integrate pro inflammatory cytokines accumulation, active microglia and volumetric changes which correlates with defective cognitive performance and neurodegeneration.

Methods: Mice from 2-,12- and 20-months-old of age were submitted to different memory tests: Y-maze, Barnes maze, object location test and object location test. Afterwards, we performed structural MRI to evaluate macrostructural changes related to memory and learning regions. Following this, we also evaluated in peripheral blood and in brain tissue the presence of pro-inflammatory cytokines …


High Illusion Of Control Adolescents: A Moderated Mediation Analyses Of The Effects Of Forms Of Counterfactual Thinking And Gender In Problem Gambling And Gaming, Larry Okechukwu Awo Dr., George Nzeadi Duru Mr. May 2023

High Illusion Of Control Adolescents: A Moderated Mediation Analyses Of The Effects Of Forms Of Counterfactual Thinking And Gender In Problem Gambling And Gaming, Larry Okechukwu Awo Dr., George Nzeadi Duru Mr.

International Conference on Gambling & Risk Taking

Abstract

Three studies (Study 1, N = 322 male adolescents, Study 2, N = 401 male and female adolescents, and Study 3, longitudinal, N = 56 male and female adolescents) analyzed the effects cognitive and psychographic variables in the relationships among illusion of control (IC), problem gambling and problem gaming. Moderated mediation analyses results using PROCESS macro in the three studies confirmed: (1) the positive mediating effect of upward CFT in the association between IC and problem gambling and problem gaming; (2) the negative mediating effect of downward CFT in the association between IC and problem gambling and problem gaming; …


Psychosocial Characteristics Of Gambling Addicts – Does It Matter When They Start Their Treatment?, Neven Ricijas Phd, Dora Dodig Hundric Phd, Sabina Mandic Ma, Sanja Radic Bursac Ma, Davor Bodor Phd May 2023

Psychosocial Characteristics Of Gambling Addicts – Does It Matter When They Start Their Treatment?, Neven Ricijas Phd, Dora Dodig Hundric Phd, Sabina Mandic Ma, Sanja Radic Bursac Ma, Davor Bodor Phd

International Conference on Gambling & Risk Taking

Abstract:

Gambling disorder is well known as a hidden addiction and therefore is subjected to a prolonged time in seeking treatment. During the development of addiction, the psychosocial functioning is more openly or covertly disrupted, and gambling addicts manifest various problems and risky behaviors. At the same time, motivational mechanism for seeking professional help are complex and influenced by different individual circumstances.

This study was conducted with N=315 patients in the Daily Clinic for Gambling Addiction. The psychosocial functioning of the patients is assessed at the beginning of the treatment, while a specific aim of this paper is to explore …


Does Accountability Affect Adherence To Moisturizer Treatment In Atopic Patients With Xerosis?, Stuti Prajapati, Christina Kontzias, Steven Feldman May 2023

Does Accountability Affect Adherence To Moisturizer Treatment In Atopic Patients With Xerosis?, Stuti Prajapati, Christina Kontzias, Steven Feldman

Rowan-Virtua Research Day

Introduction: Xerosis is common in atopic dermatitis (AD). Adherence depends on factors such as complexity of treatments, disease understanding and accountability. Accountability is a psychobehavioral construct, referring to the expectation that one must be responsible for their actions or inactions.

Objective: We sought to assess whether interventions expected to improve accountability would be associated with improved adherence to xerosis treatment.

Method: This is a prospective study of 30 patients diagnosed with xerosis . Patients were given moisturizer with an electronic monitor to record adherence and asked to apply it once daily for three months. Subjects were randomized into one of …


Comorbidities, Behaviors, And Socioeconomic Factors And Mortality From Diseases Of The Heart In New Jersey, Matthew Guariglia, Stephen Poos, Ahmed Gawash, David Lo, Aayush Visaria May 2023

Comorbidities, Behaviors, And Socioeconomic Factors And Mortality From Diseases Of The Heart In New Jersey, Matthew Guariglia, Stephen Poos, Ahmed Gawash, David Lo, Aayush Visaria

Rowan-Virtua Research Day

Mortality from diseases of the heart claimed the lives of 186,074 New Jerseyans from 2010 to 2019. This study aims to establish correlations between each of health-related risk factors and death from heart disease in each of six New Jersey counties. Each of the counties ranked by age-adjusted mortality per 100,000 from diseases of the heart. The six counties were divided by the least (Hunterdon, Somerset, Bergen) and greatest (Cape May, Salem, and Cumberland) mortality rates from heart disease. Additionally, this data was broken down into three main categories that include comorbidities, socioeconomic status, and behavior patterns. Each main category …


Prevalence Of Disordered Eating In Female Athletes Of The New Jersey Athletic Conference, Desiree Brower, Joanna Petrides May 2023

Prevalence Of Disordered Eating In Female Athletes Of The New Jersey Athletic Conference, Desiree Brower, Joanna Petrides

Rowan-Virtua Research Day

Background: In 2018, the American Academy of Child and Adolescent Psychiatry published that, 1 out of every 10 adolescent females suffer from an eating disorder in the United States. Although it is known that eating disorders have an impact on the entire population, there are currently no studies on the prevalence of disordered eating in female athletes of the New Jersey Athletic conference (NJAC). This study aims to determine how many athletes in this population are affected.

Methods: This IRB-approved project utilized a survey-based approach to assess the prevalence of disordered eating among female athletes within the NJAC. To participate, …


Assessing Correlation Between Manual Dexterity, Specialty Choice And Desire To Practice Omt In Newly Admitted Osteopathic Medical Students, Valerie Rome, Nils Brolis May 2023

Assessing Correlation Between Manual Dexterity, Specialty Choice And Desire To Practice Omt In Newly Admitted Osteopathic Medical Students, Valerie Rome, Nils Brolis

Rowan-Virtua Research Day

Is there any relationship between manual dexterity, specialty choice, and the use of osteopathic manipulative treatment (OMT) in newly-admitted osteopathic medical students? Hand dexterity has previously been associated with surgical skill development in medical residents. There is currently a gap in the scientific literature in regards to the use of one’s hands and the career choice they ultimately pursue, in addition to interest in performing OMT in their respective fields. To help elucidate the answer this question, this SMRF project aimed to evaluate the relationship between manual dexterity, specialty choice, and use of osteopathic manipulative treatment (OMT) in newly admitted …


A Clinician's Guide To 23andme: A Survey-Based Study On People’S Attitudes And Actions Towards Direct-To-Consumer Genetic Testing, Julia Kiffel, Rifke Anolik, Alexander Kowalski May 2023

A Clinician's Guide To 23andme: A Survey-Based Study On People’S Attitudes And Actions Towards Direct-To-Consumer Genetic Testing, Julia Kiffel, Rifke Anolik, Alexander Kowalski

Rowan-Virtua Research Day

Background: While direct-to-consumer (DTC) at-home genetic testing like 23andMe provides users with potentially valuable information about their genetics and health risks, consumers might not have the background or knowledge to fully comprehend and interpret the results. This concept is a pressing issue because of the rise in popularity of these DTC genetic tests.

Purpose: The goal of this study is to elucidate the beliefs and attitudes of 23andMe users and determine the relationship between their test results and likelihood for taking medical action. The results from the study will give clinicians and primary care providers (PCPs) insight into how to …


The Correlation Between Traumatic Brain Injury And Incarceration Among Adult Males In The United States, Shadi Shams May 2023

The Correlation Between Traumatic Brain Injury And Incarceration Among Adult Males In The United States, Shadi Shams

Rowan-Virtua Research Day

The United States has one of the largest growing prison populations in the world. A large amount of social and economic resources go towards the cost and maintenance of correctional facilities each year. Additionally, the current correctional programs are insufficient in assisting inmates with getting back to society; especially those with traumatic brain injury (TBI) who often remain undiagnosed and are usually treated unfairly in the prison system instead of receiving the appropriate help. Prior scholarly work has shown that patients in the post-TBI stage are more likely to enter the judicial system. In the recent population-based cohort study, the …


A 5-Year Clinical Course Of Phenocopy Syndrome Of Behavioral Variant Frontotemporal Dementia: Case Report And Literature Review, Joseph Melillo, Keyur Patel, Christian White May 2023

A 5-Year Clinical Course Of Phenocopy Syndrome Of Behavioral Variant Frontotemporal Dementia: Case Report And Literature Review, Joseph Melillo, Keyur Patel, Christian White

Rowan-Virtua Research Day

Frontotemporal dementia is a neurocognitive disease which affects language, behavior, or executive functioning. This disease includes a spectrum of presentations which includes multiple variants. The phenocopy syndrome of behavioral variant frontotemporal dementia is one which mimics the behavioral variant of frontotemporal dementia. Patients with this condition show a decline in personality, social conduct and cognitive ability but often display no signs of neurological imaging and exhibit slow progression. This case focuses on a now 70-year-old male who has shown signs of behavioral changes with a slowly progressive clinical course and minimal findings on PET scan, but moderate changes seen on …


Case Report: Abrupt Psychosis Or Nmda Receptor Encephalitis?, Alexis Dunn, Neelesh Parikh, James Espinosa, Alan Lucerna May 2023

Case Report: Abrupt Psychosis Or Nmda Receptor Encephalitis?, Alexis Dunn, Neelesh Parikh, James Espinosa, Alan Lucerna

Rowan-Virtua Research Day

We report a case of a 46-year-old female who was initially committed to a psychiatric facility for new onset schizophrenia symptoms. She later had an extensive workup in the hospital due to leukocytosis and was believed to have NMDA Receptor Encephalitis as the cause for her new behavioral symptoms. This case report aims to educate EM (emergency medicine) physicians to keep a broad differential diagnosis on patients who present with new onset, unprovoked psychosis later in life.


The Effect Of Perceived Weight Status And Bmi On Food Attitudes And Food Relationships, Sahil Patel, Ryan Gericke, Jaime Dougherty, Adarsh Gupta May 2023

The Effect Of Perceived Weight Status And Bmi On Food Attitudes And Food Relationships, Sahil Patel, Ryan Gericke, Jaime Dougherty, Adarsh Gupta

Rowan-Virtua Research Day

The findings of this study have shed light on the intricate relationship that exists between perceived weight status from a “non-obese/obese” perspective and attitudes towards food and the overconsumption of particular food items. Participants who perceived their weight status as “obese” despite having a calculated BMI below the CDC threshold and classification for “obesity” had poorer relationships with food, consumption behaviors, and on average consumed food items that were detrimental to overall health. Comprehending a patient’s weight status perception and conducting a thorough history of their food intake could play a crucial role in addressing the patient’s overall health and …


Effect Of The Covid-19 Pandemic On Hpv Vaccination Rates, Jennifer Sepede, Kathy Chen May 2023

Effect Of The Covid-19 Pandemic On Hpv Vaccination Rates, Jennifer Sepede, Kathy Chen

Rowan-Virtua Research Day

Human papillomavirus (HPV) is a common sexually transmitted infection that potentiates cancer in both males and females. There are over 200 different types of HPV and while some strains, specifically HPV 6 and 11, may result in genital and skin warts, others remain clinically silent. High risk strains, HPV 16 and 18, are most associated with cervical cancer in women. During the COVID-19 pandemic, there was widespread hesitancy and rejection towards vaccination. Similarly, the Human Papilloma Virus (HPV) vaccine has also been met with distrust since it’s release. Studies have shown that there is a low vaccination rate due to …


Caretaker Burnout In Nj In Response To The Covid-19 Pandemic: A Study Focusing On Quality Of Life, Challenges And Coping Strategies., Abdullah Junayed, Joanna Petrides May 2023

Caretaker Burnout In Nj In Response To The Covid-19 Pandemic: A Study Focusing On Quality Of Life, Challenges And Coping Strategies., Abdullah Junayed, Joanna Petrides

Rowan-Virtua Research Day

There is a scarcity of literature regarding caretaker burnout in response to Covid-19, however one cross section survey study in Italy explored the perceived burden of caretakers of patients with Alzheimer’s disease during the pandemic.1 Maria G. Maggio et al showed that an increase in caregiver burden allowed for a deterioration in personal health conditions causing an increase in perceived stress levels. 1 Along with impaired management of stress and low quality of life, many caretakers were found to utilize avoidance strategies.1 However, the authors pointed out that the dysfunctional coping strategies did not affect stress levels and this study …


Body Dysmorphic-Induced Androgenic Anabolic Steroids Usage And Its Association With Mental Health Outcomes: A Systematic Review, Ahmed Gawash, Hasan Zia, David Lo May 2023

Body Dysmorphic-Induced Androgenic Anabolic Steroids Usage And Its Association With Mental Health Outcomes: A Systematic Review, Ahmed Gawash, Hasan Zia, David Lo

Rowan-Virtua Research Day

This systematic review on body dysmorphic disorder (BDD), anabolic-androgenic steroid (AAS) use, and mental health outcomes aim to examine the relationship between them. While looking at prior research, it has been suggested that individuals with BDD may be more likely to abuse AAS due to their preoccupation with appearance but, unfortunately, AAS use may worsen mental health issues in this population and exacerbate the issue. This systematic review will also discuss treatments that will help mitigate the effects of AAS on individuals with BDD. The review will include only published literature from a variety of databases such as PubMed, Scopus, …


Barriers To Colorectal Cancer Screening For Low-Income Hispanic Men In Urban Areas Between 50-75, Alex Vega May 2023

Barriers To Colorectal Cancer Screening For Low-Income Hispanic Men In Urban Areas Between 50-75, Alex Vega

Rowan-Virtua Research Day

Colorectal cancer (CRC) is the second leading cause of cancer-related deaths in the United States. Although CRC screening rates have improved in non-Hispanic whites (NHW), Hispanic adult males (HAM) aged 50-75 in urban areas continue to experience low screening rates and higher CRC morbidity and mortality. This review aims to identify the barriers to CRC screening among HAM and propose targeted interventions to increase screening rates. A comprehensive literature review was conducted using databases such as PubMed, Scopus, and Google Scholar. Key search terms included "colorectal cancer", "screening", "Hispanic adult males", "urban", "barriers", and "interventions". Factors identified include poverty, language …


Healthcare Disparities In The Lgbtqia+ Community: A Scoping Review Of Community Vs Provider Experiences, Uttara Hardikar, Alisha Vincent, Venkateswar Venkataman, Millicent Channell May 2023

Healthcare Disparities In The Lgbtqia+ Community: A Scoping Review Of Community Vs Provider Experiences, Uttara Hardikar, Alisha Vincent, Venkateswar Venkataman, Millicent Channell

Rowan-Virtua Research Day

Background: It is well-established that healthcare disparities exist in the LGBTQIA+ community. The divide is a growing concern exacerbated by recent changes in the healthcare and sociopolitical climate. To eliminate this divide and find ways to deliver better outcomes to the LGBTQIA+ is a dire need. This report analyzes the possible reasons from the community as well as the providers perspective, with a goal to find best practices that could be implemented in both components.

Methods: A scoping literature review was carried out as described below to collect perspectives from both sides: patients as well as providers.

Results: From patient …


Brief Review: Patient Pill Splitting. What Is The Appropriate Advice To Provide Patients In The Emergency Department?, Mohammad Rattu, James Espinosa, Gabriel Meister, Alan Lucerna May 2023

Brief Review: Patient Pill Splitting. What Is The Appropriate Advice To Provide Patients In The Emergency Department?, Mohammad Rattu, James Espinosa, Gabriel Meister, Alan Lucerna

Rowan-Virtua Research Day

A number of patients have inquired about the practice of pill splitting. Cutting or splitting of pills can be used by patients to create an intermediate dose or to save on money where a higher dose is priced at relatively the same cost as a lower dose. In this review we discuss a number of issues related to medication safety and table splitting.


Factors That Influence The Decision To Get Vaccinated Against Covid-19, Rhea Bhargava, Meghan H. Foos, Brandy M. Gotti, Alexandra L. Mulvenna, Taylor O. Smith, Danielle Cooley, Venkateswar Venkataman May 2023

Factors That Influence The Decision To Get Vaccinated Against Covid-19, Rhea Bhargava, Meghan H. Foos, Brandy M. Gotti, Alexandra L. Mulvenna, Taylor O. Smith, Danielle Cooley, Venkateswar Venkataman

Rowan-Virtua Research Day

Since the start of the COVID-19 pandemic and the launch of the vaccine, healthcare workers have been encouraging people to get vaccinated to prevent the spread of the virus. However, there is a significant number of people who are vaccine hesitant, or uncertain about receiving the COVID-19 vaccine and its booster. Vaccine hesitancy represents a state of opportunity to make positive change; therefore, it is crucial for healthcare workers to identify those who are in this population. When factors contributing to the vaccine hesitancy, including gender, age, ethnicity, education level, and income were studied, it was found that women, those …


Cardiovascular Disease In The Active Service: Incidence Rates And Implications For Intervention, Sophie R. Vincent Apr 2023

Cardiovascular Disease In The Active Service: Incidence Rates And Implications For Intervention, Sophie R. Vincent

Symposium of Student Scholars

Cardiovascular disease (CVD) is the number one cause of death in the United States. Common risk factors associated with CVD are obesity, hypertension, alcohol use, tobacco use, unhealthy diet, and physical inactivity. Other factors such as genetics, race, age, and gender also play a role in the development of CVD. Based on current literature, the increasing trend of obesity impacts even active-duty military service members who are paid to maintain their physical fitness. Due to the lack of literature surrounding incidences of CVDs in active service members, the present study provides insight into this topic. The present research conducted a …


Low-Dose Psilocybin Enhances Novel Object Recognition But Not Inhibitory Avoidance In Adult Rats, Claire E. Miller, Colin R. Del Valle, Margaret M. Naylor, Heather R. Sparkman, Connor M. Cruea, Rachel E. Rice, Brooke E. Bramlage, Lillianna P. Puppel, Madison L. Brown, Aleece K. Al-Olimat, Elizabeth S. Dietz, Phillip R. Zoladz Apr 2023

Low-Dose Psilocybin Enhances Novel Object Recognition But Not Inhibitory Avoidance In Adult Rats, Claire E. Miller, Colin R. Del Valle, Margaret M. Naylor, Heather R. Sparkman, Connor M. Cruea, Rachel E. Rice, Brooke E. Bramlage, Lillianna P. Puppel, Madison L. Brown, Aleece K. Al-Olimat, Elizabeth S. Dietz, Phillip R. Zoladz

ONU Student Research Colloquium

Given the recently renewed interest in using psychedelics to aid in the treatment of psychological disorders, we aimed to examine the impact of psilocybin, a 5-HT2A agonist, on learning and memory in rodents. Previous work has demonstrated that psilocybin and other 5-HT2A agonists can enhance fear conditioning, fear extinction, and novel object recognition (NOR). Thus, we predicted that low doses of psilocybin would enhance inhibitory avoidance (IA) and NOR memory. In the first experiment, adult male and female Sprague-Dawley rats underwent step-through IA training (involving 0.45, 0.65, or 1 mA scrambled footshock) and were injected intraperitoneally (i.p.) with …


Psilocybin Prevents Symptoms Of Hyperarousal And Enhances Novel Object Recognition In Rats Exposed To The Single Prolonged Stress Paradigm, Colin R. Del Valle, Heather R. Sparkman, Margaret M. Naylor, Connor M. Cruea, Rachel E. Rice, Claire E. Miller, Brooke E. Bramlage, Lillianna P. Puppel, Madison L. Brown, Aleece K. Al-Olimat, Elizabeth S. Dietz, Phillip R. Zoladz Apr 2023

Psilocybin Prevents Symptoms Of Hyperarousal And Enhances Novel Object Recognition In Rats Exposed To The Single Prolonged Stress Paradigm, Colin R. Del Valle, Heather R. Sparkman, Margaret M. Naylor, Connor M. Cruea, Rachel E. Rice, Claire E. Miller, Brooke E. Bramlage, Lillianna P. Puppel, Madison L. Brown, Aleece K. Al-Olimat, Elizabeth S. Dietz, Phillip R. Zoladz

ONU Student Research Colloquium

Pharmacotherapy for stress-related psychological disorders remains inadequate. Patients who are treated with conventional pharmacological agents frequently report negligeable symptom reduction, and, in most cases, less than 50% experience full remission. Clearly, there is a need for additional pharmaceutical research into both established and novel approaches to alleviate these conditions. Over the past several years, there has been a renewed interest in the use of psychedelics to aid in the treatment of psychological disorders. Several studies have reported promising results in patients with major depression, anxiety disorders, and post-traumatic stress disorder (PTSD) following treatment with psychedelic agents such as lysergic acid …


Tunnel Vision, False Memories, And Intrusive Memories Following Exposure To The Trier Social Stress Test, Chloe N. Cordes, Cassidy L. Pfister, Kayla M. Boaz, Taylor D. Niese, Sydney L. Parker, Kristen E. Long, Mercedes L. Stanek, Matthew S. Risner, John G. Blasco, Koen N. Suzelis, Kelsey M. Siereveld, Shannon B. Carnes, Boyd R. Rorabaugh, Phillip R. Zoladz Apr 2023

Tunnel Vision, False Memories, And Intrusive Memories Following Exposure To The Trier Social Stress Test, Chloe N. Cordes, Cassidy L. Pfister, Kayla M. Boaz, Taylor D. Niese, Sydney L. Parker, Kristen E. Long, Mercedes L. Stanek, Matthew S. Risner, John G. Blasco, Koen N. Suzelis, Kelsey M. Siereveld, Shannon B. Carnes, Boyd R. Rorabaugh, Phillip R. Zoladz

ONU Student Research Colloquium

Most research examining the impact of stress on learning and memory has exposed participants to a stressor and measured how it affects learning and memory for unrelated material (e.g., list of words). Such work has been helpful, but it has not been the most translational to the human condition. When considering phenomena such as intrusive memories in post-traumatic stress disorder (PTSD) or an eyewitness's memory for a crime, it is most useful to know what an individual remembers about the stress experience itself, not unrelated information. In prior work, investigators used a modified version of the Trier Social Stress Test …


Impact Of Acute Stress, Sex, And Childhood Maltreatment On Fear Learning And Fear Generalization In A Fear-Potentiated Startle Paradigm, Kayla M. Boaz, Chloe N. Cordes, Cassidy L. Pfister, Taylor D. Niese, Sydney L. Parker, Kristen E. Long, Mercedes L. Stanek, Boyd R. Rorabaugh, Seth D. Norrholm, Phillip R. Zoladz Apr 2023

Impact Of Acute Stress, Sex, And Childhood Maltreatment On Fear Learning And Fear Generalization In A Fear-Potentiated Startle Paradigm, Kayla M. Boaz, Chloe N. Cordes, Cassidy L. Pfister, Taylor D. Niese, Sydney L. Parker, Kristen E. Long, Mercedes L. Stanek, Boyd R. Rorabaugh, Seth D. Norrholm, Phillip R. Zoladz

ONU Student Research Colloquium

Many researchers approach the etiology of trauma-, stressor-, and anxiety-related mental disorders from the perspective of classical conditioning processes gone awry. According to this view, abnormal associative relationships between conditioned and unconditioned stimuli may underlie pathological anxiety and result in unusually intense fear memories or fear memories that cannot be properly extinguished. Recent work has expanded on this view by showing that many psychological disorders involving pathological anxiety are associated with an exaggerated form of stimulus generalization, leading individuals with such disorders to respond with fear and anxiety to a variety of contexts and cues that should not be threatening. …


Understanding The Contributions Of Hormonal Contraceptives And Cortisol Levels To Fear Learning In Women, Sahil Bardai Dec 2022

Understanding The Contributions Of Hormonal Contraceptives And Cortisol Levels To Fear Learning In Women, Sahil Bardai

Symposium of Student Scholars

Women are twice as likely to be diagnosed with an anxiety disorder than men. Eighty-five percent of women in the US will use hormonal contraceptives at some point in their lifetime. Women who use hormonal contraceptives show heightened startle reactivity to a threatening stimulus. Previous results from our lab showed a significant increase in fear-potentiated startle (FPS) in women who were on hormonal contraceptives compared to women who were naturally cycling. These results stayed consistent throughout three acquisition trials. Others have shown that the use of OCPs (oral contraceptive pills) is related to the dysregulation of the HPA-axis and elevated …


Bullying Victimization Among Children With Mental, Emotional, Developmental, Or Behavioral Problems - A Us Population-Based Study, Saral Desai Oct 2022

Bullying Victimization Among Children With Mental, Emotional, Developmental, Or Behavioral Problems - A Us Population-Based Study, Saral Desai

Tower Health Research Day

No abstract provided.


The Effects Of Prenatal Cannabis Exposure On The Basolateral Amygdala, Karen Kw Wong Aug 2022

The Effects Of Prenatal Cannabis Exposure On The Basolateral Amygdala, Karen Kw Wong

Undergraduate Student Research Internships Conference

Clinical and preclinical studies indicate prenatal cannabis exposure (PCE) pathologically affects fetal brain development and may increase vulnerability to neuropsychiatric disorders, including schizophrenia and mood/anxiety disorders. In review research from our lab suggests that fetal exposure to Δ9-THC sex-selectively impairs mesocorticolimbic (MCL) circuit function. However, there is a distinct lack of focus on PCE models on the BLA. The BLA plays a central role within the MCL where it directly interacts with the VTA, PFC and HIPP. Importantly, our model exhibits significant VTA hyperdopaminergic activity, and sex-specific alterations to PFC/HIPP glutamate firing, alongside region- and sex-specific changes in dopamine (DA), …


The Effects Of The Aromatase Inhibitor, Letrozole, On Lithium Chloride (Licl)-Induced Conditioned Disgust Behaviour (Anticipatory Nausea) In Male Rats, Vangel Matic Aug 2022

The Effects Of The Aromatase Inhibitor, Letrozole, On Lithium Chloride (Licl)-Induced Conditioned Disgust Behaviour (Anticipatory Nausea) In Male Rats, Vangel Matic

Undergraduate Student Research Internships Conference

Anticipatory Nausea (AN) is a form of classical conditioning in which the effects of a nausea-inducing toxin become associated with a specific environmental context. AN is often experienced by individuals receiving chemotherapy treatment, whereby the emetic effects of the chemotherapy agents become associated with the treatment context (i.e. hospital, clinic), such that exposure to the context alone can cause an individual to experience nausea and potentially withdraw from treatment. Chemotherapy-associated AN is suggested to have a higher incidence in females compared to males.

AN can be represented in a rodent model (conditioned disgust) through the occurrence of conditioned gaping behaviour …


Trends In Pediatric Obesity Of School-Aged Children During The Covid-19 Pandemic, Maryanna Schweininger, Amaani Faizal, Suzanna Hosein May 2022

Trends In Pediatric Obesity Of School-Aged Children During The Covid-19 Pandemic, Maryanna Schweininger, Amaani Faizal, Suzanna Hosein

Rowan-Virtua Research Day

Since the start of the COVID-19 pandemic, children have been more sedentary due to nationwide school closures resulting in classes being held virtually. Due to restrictions, children could no longer participate in physical education classes and after school activities at the same frequency. The pandemic also placed a disproportionate burden on low-income families thus, potentially amplifying food insecurity. The aim of this study was to identify the impact of the COVID-19 pandemic on childhood obesity.