Behavior and Behavior Mechanisms Commons^™

Septohippocampal Gabaergic Neurons Mediate The Altered Behaviors Induced By N-Methyl-D-Aspartate Receptor Antagonists., Jingyi Ma, Siew Kian Tai, L Stan Leung

Physiology and Pharmacology Publications

We hypothesize that selective lesion of the septohippocampal GABAergic neurons suppresses the altered behaviors induced by an N-methyl-D-aspartate (NMDA) receptor antagonist, ketamine or MK-801. In addition, we hypothesize that septohippocampal GABAergic neurons generate an atropine-resistant theta rhythm that coexists with an atropine-sensitive theta rhythm in the hippocampus. Infusion of orexin-saporin (ore-SAP) into the medial septal area decreased parvalbumin-immunoreactive (GABAergic) neurons by ~80%, without significantly affecting choline-acetyltransferase-immunoreactive (cholinergic) neurons. The theta rhythm during walking, or the immobility-associated theta induced by pilocarpine, was not different between ore-SAP and sham-lesion rats. Walking theta was, however, more disrupted by atropine sulfate in ore-SAP than …

The Change Program: Comparing An Interactive Versus Prescriptive Telephone-Based Behavioural Intervention On The Psychological And Physiological Profiles Of University Students With Obesity, Erin S. Pearson

Electronic Thesis and Dissertation Repository

The purpose of the CHANGE (Coaching towards Healthy Actions Naturally through Goal-related Empowerment) Program was to compare the effectiveness of an interactive versus prescriptive 12-week telephone-based behavioural intervention on the psychological and physiological profiles of university students with obesity. Motivational Interviewing administered using Co-Active Life Coaching (MI-via-CALC) and a structured lifestyle treatment following the LEARN (Lifestyle, Exercise, Attitudes, Relationships, Nutrition) Program for Weight Management were examined.

Article 1 provided a methodological account of the CHANGE Program which included a detailed rationale for its development and a comprehensive description of the methods used. Because goal setting has been established as an …

Individual Differences In White Matter Microstructure Predict Mathematical Achievement, Anna A. Matejko

Electronic Thesis and Dissertation Repository

The current study uses diffusion tensor imaging to test whether individual differences in white matter predict performance on the math subtest of the preliminary Scholastic Aptitude Test (PSAT). Grade 10 and 11 PSAT scores were obtained from 30 young adults (ages 17- 18) with wide-ranging math achievement levels. Tract based spatial statistics was used to examine the correlation between PSAT math scores, fractional anisotropy (FA), radial diffusivity (RD) and axial diffusivity (AD). FA in left parietal white matter was positively correlated with math PSAT scores (specifically in the left superior longitudinal fasciculus, left superior corona radiata, and left corticospinal tract). …