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Full-Text Articles in Substance Abuse and Addiction

Brain-Specific Serine/Threonine-Protein Kinase 1 Is A Substrate Of Protein Kinase C Epsilon Involved In Sex-Specific Ethanol And Anxiety Phenotypes, Michael P. Dugan, Rajani Maiya, Caleb Fleischer, Michal Bajo, Angela E. Snyder, Ashwin Koduri, Sathvik Srinivasan, Marisa Roberto, Robert O. Messing Mar 2024

Brain-Specific Serine/Threonine-Protein Kinase 1 Is A Substrate Of Protein Kinase C Epsilon Involved In Sex-Specific Ethanol And Anxiety Phenotypes, Michael P. Dugan, Rajani Maiya, Caleb Fleischer, Michal Bajo, Angela E. Snyder, Ashwin Koduri, Sathvik Srinivasan, Marisa Roberto, Robert O. Messing

School of Graduate Studies Faculty Publications

Protein kinase C epsilon (PKCε) regulates behavioural responses to ethanol and plays a role in anxiety-like behaviour, but knowledge is limited on downstream substrates of PKCε that contribute to these behaviours. We recently identified brain-specific serine/threonine-protein kinase 1 (BRSK1) as a substrate of PKCε. Here, we test the hypothesis that BRSK1 mediates responses to ethanol and anxiety-like behaviours that are also PKCε dependent. We used in vitro kinase assays to further validate BRSK1 as a substrate of PKCε and used Brsk1−/− mice to assess the role of BRSK1 in ethanol- and anxiety-related behaviours and in physiological responses to ethanol. We …


Identifying Associations Between The Family Environment And Anxiety And Depression Among Children Ages 0-17 In The United States, Reagan A. Richardson, Nicole M. Holt Aug 2023

Identifying Associations Between The Family Environment And Anxiety And Depression Among Children Ages 0-17 In The United States, Reagan A. Richardson, Nicole M. Holt

OUR Journal: ODU Undergraduate Research Journal

This study analyzes whether physical, emotional & neurological, family environment, or community-related factors display the strongest association with anxiety and depression among children ages 0-17 in the United States.

Using IBM SPSS v. 27, we conducted a univariate and multivariate logistic regression analysis on data from the 2017 National Survey of Children’s Health (NSCH) with a sample size of 21,599. Our independent variables included 30 questions from the NSCH which were compared to a mental health index score.

Our study shows that about 10.6% of children suffer from either anxiety, depression, or both, and the univariate model found that 19 …


Assessing The Involvement Of Projections From The Prelimbic Prefrontal Cortex To The Paraventricular Nucleus Of The Thalamus In Cocaine Withdrawal-Induced Anxiety, Clinton Coelho Apr 2023

Assessing The Involvement Of Projections From The Prelimbic Prefrontal Cortex To The Paraventricular Nucleus Of The Thalamus In Cocaine Withdrawal-Induced Anxiety, Clinton Coelho

MUSC Theses and Dissertations

Withdrawal from cocaine induces an immediate and powerful negative affective state which is characterized by feelings of agitation and anxiety in humans and anxiety-like behaviors in rodents. It has been hypothesized that the anxiogenic effects associated with cocaine withdrawal play a major role in continued cocaine use and drive relapse to cocaine seeking. The prelimbic (PL) medial prefrontal cortex is not only involved in the processing and regulation of negative emotions such as anxiety but also mediates relapse to cocaine-seeking. Subcortical hubs of the reward system that receive projections from the PL neurons are known to be dysregulated during different …


Mental Health In Pilots Ages 19-26: What Are The New Pilots Telling Us?, Jason T. Lorenzon, Diana Semilia Jan 2023

Mental Health In Pilots Ages 19-26: What Are The New Pilots Telling Us?, Jason T. Lorenzon, Diana Semilia

National Training Aircraft Symposium (NTAS)

Mental Health is stigma that reaches all professional pilots. After spending a considerable amount of money, a pilot is always afraid of losing his/her medical certification. This leads many pilots to not be honest and forthcoming about his/her own health situation or if he/she is forthcoming with any medical deficiency, the regulatory framework at the Federal Aviation Administration may put a further burden on the pilot to provide additional medical documentation, or the FAA may even amend, revoke, or suspend a pilot's medical certificate.

The Federal Aviation Administration (FAA) regulations,14 CFR Parts 61 and 67 and internal protocols creates a …


Mental Health In Sports Media, Samuel Ridgley Jan 2023

Mental Health In Sports Media, Samuel Ridgley

Communication & Media Studies | Senior Theses

This paper looks at the increasingly popular conversation surrounding mental health in sports. It provides a glimpse into how common the struggle of mental health can be for many high-level athletes while also examining the narrative and expectations that society and the media have created. The paper also provides examples of prominent athletes from a variety of different sports and delves into their personal mental health experiences in the eyes of the media. The goal of this paper is to show the progression and change of how the media portrays mental health amongst athletes in today’s ever-changing world.


Law Library Blog (October 2022): Legal Beagle's Blog Archive, Roger Williams University School Of Law Oct 2022

Law Library Blog (October 2022): Legal Beagle's Blog Archive, Roger Williams University School Of Law

Law Library Newsletters/Blog

No abstract provided.


Social Worker Student’S Anxiety, And Alcohol Consumption During The Covid-19 Pandemic, David Adler Jun 2022

Social Worker Student’S Anxiety, And Alcohol Consumption During The Covid-19 Pandemic, David Adler

Electronic Theses, Projects, and Dissertations

The COVID-19 pandemic has been extremely impactful on a vast majority of the population, either from losing a possible loved one, or the pandemonium that arose in its wake. The purpose of this study is to better understand how much of an impact the COVID-19 pandemic has had on social worker students’ mental health, specifically, how it has affected their levels of stress, anxiety, and levels of alcohol consumption. This study is significant because the pandemic has had a substantial impact on the mental health of so many individuals, and it is important to research just how large these effects …


Anxiety And Depression Among Students Using Tobacco In A Selected College Of Sonitpur District, Assam: A Crosssectional Study, Monalisa Saikia, Nurnahar Ahmed, Arunjyoti Baruah Jan 2022

Anxiety And Depression Among Students Using Tobacco In A Selected College Of Sonitpur District, Assam: A Crosssectional Study, Monalisa Saikia, Nurnahar Ahmed, Arunjyoti Baruah

Manipal Journal of Nursing and Health Sciences

Introduction: Tobacco use is one of the major public health concerns around the world, accounting for many deaths and disabilities. The use of tobacco is linked to many physical and mental ailments. A large population of adolescents are enrolled in colleges and universities in India, making them a vulnerable population for the use and abuse of tobacco. Objective: The objective of this study is to assess the level of anxiety and symptoms of depression among college-going students who consume tobacco. Methods: A descriptive cross-sectional approach was selected for the study. The purposive sampling technique was used to select college students …


S5e2: How Can We Address Mental Health Needs In Rural Maine?, Ron Lisnet, Jeff Hecker, Sandy Butler, Emily Haigh Sep 2021

S5e2: How Can We Address Mental Health Needs In Rural Maine?, Ron Lisnet, Jeff Hecker, Sandy Butler, Emily Haigh

The Maine Question

Many people nationwide are experiencing a decline in their mental health. Rates of anxiety, depression, and substance abuse are rising, more so in rural areas. Ten out of 16 Maine counties have a shortage of mental health professionals. Only about half of the state population receives the services they need.

At UMaine, a major effort is underway to recruit more mental health care providers to serve in rural areas. Using federal funding, researchers from the Psychology Department and School of Social Work are working with other experts to increase the number of psychologists, social workers and substance abuse professionals in …


Emergency Medicine Shift Factors Causing The Most Stress Among Emergency Medicine Residents, Mohamad Moussa, Kristen Hayden, Chia-Hao Shih, Sadik Khuder, Zayd Safadi, Connor Parsell Sep 2021

Emergency Medicine Shift Factors Causing The Most Stress Among Emergency Medicine Residents, Mohamad Moussa, Kristen Hayden, Chia-Hao Shih, Sadik Khuder, Zayd Safadi, Connor Parsell

Journal of Wellness

Introduction: Past studies demonstrate that stress and anxiety affect emergency medicine physicians, but the causal factors identified are usually from sources outside the work shift. We attempt to show the relationship between intrinsic factors of a work shift and anxiety perceived by residents, while also examining differing gender responses.

Methods: In 2018, a cross-sectional survey of emergency medicine residents in the United States was distributed anonymously through the Emergency Medicine Residents Association. The survey consisted of demographic questions, novel questions identifying intrinsic factors, and the Generalized Anxiety Disorder 7-item (GAD-7) scale. Spearman correlation, independent t-test, and multivariate analysis of variance …


Anxious Times And Anxiety Drugs, Noah Atlas, Austin Mcneill Brown Jan 2021

Anxious Times And Anxiety Drugs, Noah Atlas, Austin Mcneill Brown

Population Health Research Brief Series

The COVID-19 pandemic has caused rising anxiety and a corresponding increase in benzodiazepine prescriptions. Experts worry that inconsistent access to physicians as a result of stay-at-home orders will lead dependent patients to seek counterfeit or street drugs if their prescriptions lapse. This brief discusses these repercussions and recommends approaches to monitor and support those suffering from anxiety.


The Impact Of Mother And Adolescent Offspring Distress Reduction Training On Maternal Anxiety And Alcohol Related Behaviors Following Conflict, Sarah Ann Bilsky Aug 2019

The Impact Of Mother And Adolescent Offspring Distress Reduction Training On Maternal Anxiety And Alcohol Related Behaviors Following Conflict, Sarah Ann Bilsky

Graduate Theses and Dissertations

Nearly half of people suffering from psychopathology meet criteria for more than one disorder. Scholars have focused on understanding factors that may simultaneously maintain multiple psychiatric problems. Elevated distress during interpersonal conflict is likely to maintain both alcohol use and anxiety psychopathology. Reducing distress elicited by normative mother-adolescent conflict holds particular promise. Conflict is common in families with problematic drinking and anxiety disorders and the affective impact of parent-offspring conflict is malleable. Distress reduction skills, such as cognitive reappraisal, are effective in reducing distress during conflict. The current study examined the unique and combined effects of training mothers and adolescents …


Substance Use Disorders, Violence, Mental Health, And Hiv: Differentiating A Syndemic Factor By Gender And Sexuality, Kiyomi Tsuyuki, Eileen V. Pitpitan, Maria A. Levi-Minzi, Lianne A. Urada, Steven P. Kurtz, Jamila K. Stockman, Hilary L. Surratt Aug 2017

Substance Use Disorders, Violence, Mental Health, And Hiv: Differentiating A Syndemic Factor By Gender And Sexuality, Kiyomi Tsuyuki, Eileen V. Pitpitan, Maria A. Levi-Minzi, Lianne A. Urada, Steven P. Kurtz, Jamila K. Stockman, Hilary L. Surratt

Center for Health Services Research Faculty Publications

This paper measures syndemic substance use disorder, violence, and mental health and compares the syndemic among HIV-infected heterosexual men, heterosexual women, and men who have sex with men (MSM). Data were from a sample of high needs substance-using, HIV-infected people in South Florida between 2010 and 2012 (n = 481). We used confirmatory factor analysis to measure a syndemic latent variable and applied measurement invariance models to identify group differences in the data structure of syndemic co-morbidities among heterosexual men, heterosexual women, and MSM. We found that variables used to measure the syndemic fit each sub-group, supporting that substance use …


Chronic Pancreatitis, Pain, And Anxiety In An Alcohol And High Fat Mouse Model, Tiffanie Clinkinbeard Jan 2016

Chronic Pancreatitis, Pain, And Anxiety In An Alcohol And High Fat Mouse Model, Tiffanie Clinkinbeard

Theses and Dissertations--Gerontology

Homeodynamic space (HDS) shrinks as vulnerability increases with aging and repeated damage to the cells. HDS is lost in alcoholic pancreatitis patients due to overconsumption of alcohol, smoking, and high fat diets. Etiologically relevant animal models for study of chronic pancreatitis (CP) are needed. In order to begin filling this gap a central purpose of this dissertation research was to examine relationships between the alcohol and high fat diet (AHF) and pancreatitis with attention to hypersensitivity and anxiety-like behaviors. The AHF diet induced pancreatitis described here etiologically mimics human risk factors of AHF consumption for advancement to alcoholic CP.

In …


Research Brief: "Alcohol Use And Craving Among Veterans With Mental Health Disorders And Mild Traumatic Brain Injury", Institute For Veterans And Military Families At Syracuse University May 2015

Research Brief: "Alcohol Use And Craving Among Veterans With Mental Health Disorders And Mild Traumatic Brain Injury", Institute For Veterans And Military Families At Syracuse University

Institute for Veterans and Military Families

This brief is about the relation between alcohol craving and mental health disorders among veterans, and how mental health disorders impact alcohol cravings. For policy and practices, the research shows that alcohol cravings and mental health disorders among veterans could be a sign for risk of alcohol use disorder. It also shows that the VA should assess veterans for alcohol use disorder, and also research more ties between mental health disorders and alcohol use. Suggestions for future research include conducting the study in a larger, more representative population, as well as involving families in measuring alcohol use/cravings to ensure less …


Drink Like A Lawyer: The Neuroscience Of Substance Use And Its Impact On Cognitive Wellness, Debra S. Austin Apr 2015

Drink Like A Lawyer: The Neuroscience Of Substance Use And Its Impact On Cognitive Wellness, Debra S. Austin

Sturm College of Law: Faculty Scholarship

Lawyers suffer from higher levels of anxiety and depression than the rest of the population, but most do not enter law school with these mental health issues. Disciplinary actions against attorneys involve substance abuse 50 to 75 percent of the time. However, neuroscience research has shown that both the brain and the genes enjoy the power of plasticity, which means that personal choices and environments shape the development of lawyers throughout their lives. Legal educators need a better understanding of what aspects or characteristics of legal education contribute to the decline in mental health of law students, lawyers, and judges, …


Attachment, Anxiety, And Depression: A Study Of Women In Residential Treatment With Their Children At The Susan B. Anthony Recovery Center (Sbarc) (1995-2010), Gary Miles Forrest Jan 2015

Attachment, Anxiety, And Depression: A Study Of Women In Residential Treatment With Their Children At The Susan B. Anthony Recovery Center (Sbarc) (1995-2010), Gary Miles Forrest

Department of Family Therapy Dissertations and Applied Clinical Projects

The Susan B. Anthony Recovery Center (SBARC) in Pembroke Pines, Florida is a residential center where women live with their children while receiving treatment for a variety of co-occurring substance abuse and mental health issues and while participating in mandatory parenting classes. Unlike most women's residential treatment centers, which address only the woman and her problems, SBARC treats the mother-infant/child dyad. I designed and created a database to examine the data previously available only in the paper client records of over 800 women who received treatment at SBARC from 1995 through 2010 in a previous project. This nonexperimental, retrospective explanatory …


Generalizing Anxiety, Center For Public Service Oct 2013

Generalizing Anxiety, Center For Public Service

SURGE

As she began reading the list of symptoms, I was making mental check marks next to the ones that applied to me.

Fear of interacting with strangers- check. Fear that others will notice that you look anxious- check. Avoiding doing things or talking to people out of fear of embarrassment- check. Fear of situations in which you may be judged- check. Anxiety that disrupts your daily routine, work or school activities- check, check, check. [excerpt]


Help-Negation And Suicidal Ideation: The Role Of Depression, Anxiety And Hopelessness., Coralie J. Wilson Dec 2009

Help-Negation And Suicidal Ideation: The Role Of Depression, Anxiety And Hopelessness., Coralie J. Wilson

Frank Deane

Help-negation is expressed behaviorally by the refusal or avoidance of available help and cognitively by the inverse relationship between self-reported symptoms of psychological distress and help-seeking intentions. The current study is part of a larger multi-cite research program developed and led by the first author. It examines the association between suicidal ideation and intentions to seek help from friends, family and professional mental health sources in a sample of 302 Australian university students. Participants were 77.5% female and aged from 18-25 years old, with 85.4% aged 21 years or younger. Higher levels of suicidal ideation were related to lower help-seeking …


Help-Negation And Suicidal Ideation: The Role Of Depression, Anxiety And Hopelessness., Coralie J. Wilson Dec 2009

Help-Negation And Suicidal Ideation: The Role Of Depression, Anxiety And Hopelessness., Coralie J. Wilson

Coralie J Wilson

Help-negation is expressed behaviorally by the refusal or avoidance of available help and cognitively by the inverse relationship between self-reported symptoms of psychological distress and help-seeking intentions. The current study is part of a larger multi-cite research program developed and led by the first author. It examines the association between suicidal ideation and intentions to seek help from friends, family and professional mental health sources in a sample of 302 Australian university students. Participants were 77.5% female and aged from 18-25 years old, with 85.4% aged 21 years or younger. Higher levels of suicidal ideation were related to lower help-seeking …