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- Anca associated vasculitis (1)
- Ancaassociated vasculitis (1)
- Case reports (1)
- Cyclophosphamide (1)
- Dermatomyositis (1)
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- Drug induced pneumonitis (1)
- Gastrointestinal bleeding (1)
- Ground-glass opacity (1)
- Hispanic female (1)
- Hispanic population (1)
- Intestinal dysmotility (1)
- Myopathy related constipation (1)
- Non-specific interstitial pneumonia (1)
- Panca/mpo (myeloperoxidase)-positive microscopic polyangiitis (mpa) (1)
- Pauci-immune glomerulonephritis (gn) (1)
Articles 1 - 3 of 3
Full-Text Articles in Rheumatology
It Is Not Pneumocystis Jiroveci (Pcp), It Is Cyclophosphamide-Induced Pneumonitis, Mery Bartl, Yilen Karen Ng-Wong, Blesset Alexander, Jose Gomez Casanovas, Josenny L. Rodriguez-Paez, Andres Suarez, Christine Loftis
It Is Not Pneumocystis Jiroveci (Pcp), It Is Cyclophosphamide-Induced Pneumonitis, Mery Bartl, Yilen Karen Ng-Wong, Blesset Alexander, Jose Gomez Casanovas, Josenny L. Rodriguez-Paez, Andres Suarez, Christine Loftis
School of Medicine Publications and Presentations
Cyclophosphamide (CYC) is an immunosuppressive medication used to treat life-threatening complications of various rheumatic diseases like vasculitis and systemic lupus erythematosus. A rare side effect of this medication is pneumonitis, which occurs in less than 1% of patients. We describe a case of an 83-year-old woman with a past medical history of microscopic polyangiitis, who presented with progressive dyspnea at rest, exacerbated on exertion, and associated with orthopnea that was attributed to CYC-induced pneumonitis. Three months before this presentation, the patient was diagnosed with antineutrophil cytoplasmic antibodies (ANCA)-positive pauci-immune crescentic and necrotizing glomerulonephritis and started on CYC. On admission, a …
Acquired Factor Viii Deficiency Presenting As Gross Hematuria In A Hispanic, Pregnant Patient With Previously Undiagnosed Connective Tissue Disease, Christine Loftis, Emilia C. Dulgheru, Rosa White
Acquired Factor Viii Deficiency Presenting As Gross Hematuria In A Hispanic, Pregnant Patient With Previously Undiagnosed Connective Tissue Disease, Christine Loftis, Emilia C. Dulgheru, Rosa White
School of Medicine Publications and Presentations
Acquired factor VIII deficiency is a bleeding disorder caused by the presence of autoantibodies against clotting factor VIII. We report a case of a 24-year-old pregnant woman who presented with gross hematuria secondary to acquired factor VIII deficiency in the presence of a previously undiagnosed connective tissue disease. *is article includes a literature review of pregnancy-related cases of acquired factor VIII deficiency. We also reviewed various therapeutic approaches for the management of the acquired factor inhibitor which include achieving hemostasis and elimination of the inhibitor via immunosuppressive agents. *is case report describes the rare presentation of acquired factor VIII deficiency …
Dermatomyositis- Related Intestinal Dysmotility, Christine Loftis, Rosa White, Emilia C. Dulgheru
Dermatomyositis- Related Intestinal Dysmotility, Christine Loftis, Rosa White, Emilia C. Dulgheru
School of Medicine Publications and Presentations
Dermatomyositis (DM) is an inflammatory myopathy (IIM) characterized by proximal muscle weakness and pathognomonic skin lesions. A 69-year-old woman with a recent diagnosis of DM 1 month prior, treated with corticosteroids and immunomodulators, presented to our inpatient rehabilitation with worsening dysphagia and constipation. At the time of our evaluation, physical examination was notable for erythematous papules over the metacarpophalangeal joints, proximal interphalangeal joints, elbows, and knees as well as a violaceous rash on the face. Muscle strength was diminished bilaterally with proximal distribution being affected greater than distal. Laboratory studies were notable for the creatine kinase (CK) level of 31 …