Medical Specialties Commons^™

Osteoporosis As A Community Health Problem: Lessons Learned From Studying Hypertension, Michael Kleerekoper, Dorothy A. Nelson

Henry Ford Hospital Medical Journal

Campaigns to increase the medical and lay communities' awareness and understanding of the problems of unrecognized and untreated hypertension have led to a progressive decline in morbidity and mortality from hypertension-related diseases. While osteoporosis is also a community health problem, educational and awareness campaigns are still in their infancy and decades may pass before these result in a declining morbidity and mortality from osteoporosis. We identify areas where concepts learned from years of hypertension research might be applicable lo the study of osteoporosis as a community health problem and thereby lessen the time needed to effect a declining morbidity and …

Occurrence Of Alzheimer Disease In Michigan: An Epidemiologic Review Of Rates And Risk Factors, Christine Cole Johnson

Henry Ford Hospital Medical Journal

Alzheimer disease is a progressive degenerative neurological disorder of insidious onset characterized by the deterioration of cognitive functioning. Little is known about the etiology and epidemiology of this condition. The only risk factor consistently associated with Alzheimer disease is advancing age. As the population of the elderly continues to grow, many public agencies, including those in Michigan, are concerned about social, personal, and financial implications and seek estimates of the number of people with dementia. To date, mortality rates based on vital statistics have been noninformative because Alzheimer disease is difficult lo diagnose clinically and has been considered to be …

Conrad Ramsey Lam, Md: Henry Ford Hospital's First Heart Surgeon, Donald J. Magilligan

Henry Ford Hospital Medical Journal

No abstract provided.

Back Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Sensitivity To Sulfited Foods Among Sulfite-Sensitive Subjects With Asthma, Steve L. Taylor, Robert K. Bush, John C. Selner, Julie A. Nordlee, Matthew B. Wiener, Karen Holden, Jerald W. Koepke, William W. Busse

Department of Food Science and Technology: Faculty Publications

Eight individuals with asthma who had been diagnosed as sulfite sensitive on the basis of double-blind capsule-beverage challenges were subjected to challenges with various sulfited foods, including lettuce, shrimp, dried apricots, white grape juice, dehydrated potatoes (as mashed potatoes), and mushrooms. Four of these patients failed to respond to challenges with any of the sulfited foods. The other four patients experienced a decrease in pulmonary function on double-blind challenges with sulfited lettuce. Two of three of these patients reacted to challenges with dried apricots and white grape juice; the fourth patient has not yet been challenged with these products. Only …

The Development And Application Of A Multiple Regression Equation That Predicts The Sum Of Triceps And Subscapular Skinfolds In Children Ages 10-18, Pamela Luna-Raffy

Loma Linda University Electronic Theses, Dissertations & Projects

The purpose of this study was to develop a tool to predict the sum of triceps and subscapular skinfolds in children ages 10-18. In addition, school-based weight management programs were reviewed.

Skinfold calipers are often used to assess body fat percentage, particularly in non-clinical settings, test sites recommended by researchers are the triceps and The subscapular skinfolds. Recently, however, educators have reported two concerns about using skinfold calipers in the schools: (1) Specialized training and equipment are required, and (2) individuals must remove their clothing from selected test sites.

For schools where the use of calipers present problems, it seemed …

Decreased Triiodothyronine Binding To The Hepatic Nuclear Thyroid Hormone Receptor In The Diabetic Mouse, Thomas J. Dewind

Loma Linda University Electronic Theses, Dissertations & Projects

The diabetic C57BL/KsJ-db m mouse has abnormal thyroid hormone levels and indications of thyroid hormone resistance. To investigate the basis of these abnormalities, the hepatic nuclear thyroid hormone receptor was extracted with 0.4 M KCl, 1.1 mM MgCl₂, 20 mM Tris/HCl, pH 7.9 from hepatocyte nuclei of normal C57BL/KsJ, heterozygous C57BL/KsJ-db m (db/m), and diabetic C57BL/KsJ-db m (db/db) mice. Normal and heterozygous mice were grouped together as the controls. Triiodothyronine (T₃) binding studies at 4°C using nitrocellulose filtration to separate free T₃ from receptor bound T₃ demonstrated an …

Treatment Of Periodontal Furcation Defects, Michael Martin, Bernard Gantes

Loma Linda University Electronic Theses, Dissertations & Projects

[Note: Three parts in one.]

I. Review of the Literature and Description of a Regeneration Surgical Technique

This report provides an abbreviated review of the literature on treatment and prognosis of periodontal furcation lesions. In addition, it describes a surgical technique designed to accomplish bone regeneration in class II furcation defects, together with the rationale for the development of this procedure. Results of treatment of 30 defects with this technique are presented in a subsequent report (Gantes et al. 1987).

II. Bone Regeneration in Mandibular Class II Defects

A total of 30 mandibular, buccal class II furcation defects were treated …

Obesity And Hypertension: A Review, Khaled Imam, James R. Sowers

Henry Ford Hospital Medical Journal

Hypertension is an important risk factor for cardiovascular morbidity and mortality. Obesity is often associated with hypertension. This strong association can be attributed to several pathophysiological changes which occur in obese subjects: increased salt and caloric intake, increased blood volume, increased cardiac output, increased basal as well as stress-stimulated sympathetic nervous system activity, hyperinsulinemia, and a relative increase in renin and aldosterone. Obesity usually increases the preload and causes an eccentric cardiac hypertrophy, while hypertension increases the afterload and causes concentric cardiac hypertrophy. When both obesity and hypertension occur in the same patient (as is often the case), they present …

Blood Pressure Changes And Weight Changes In Hypertensive Patients In An Inner-City Clinic, A. David Goldberg, Frits Van Der Kuyp, Pamela C. Keenen

Henry Ford Hospital Medical Journal

The association of obesity and hypertension has been clearly established. Despite evidence that weight loss reduces blood pressure, this aspect of treatment is often not stressed. We studied the effects of nutritional intervention in a group of inner-city, predominantly black, hypertensive patients to determine resultant blood pressure changes. Weight reduction was achieved by 57% of the patients, with a loss of more than 4.5 kg (10 lb) in 18%. Changes in weight were highly correlated with blood pressure changes. Correlations were greater for systolic than diastolic pressures, for pressure measured in the standing than the supine position, and for men …

Surgery For Morbid Obesity: A Continuing Challenge, Brack A. Bivins, Farouck N. Obeid, H. Mathilda Horst, Victor J. Sorensen

Henry Ford Hospital Medical Journal

No abstract provided.

Morbidity And Treatment Of Clinically Important Obesity: An Internal Medicine Perspective, J. David Fachnie

Henry Ford Hospital Medical Journal

Obesity is defined as an excess storage of energy in the form of fat. The internist generates a differential diagnosis of etiologic factors and examines the patient carefully. Obese persons are counseled on all medical risks of obesity. Choices for treatment vary according lo the severity of the obesity, and alternative dietary treatments include a balanced-deficit diet or a very low calorie diet. Weight loss can be predicted by applying specified equations. With severe obesity, multidisciplinary treatment is needed. Anorexic agents have limited value because of their side effects and because of weight increase after discontinuing therapy. Obesity is not …

Significance Of Antinuclear Antibody (Ana) Immunofluorescent Patterns And Titers In Systemic Lupus Erythematosus Nephritis, Syed Akbar, Abel I. Tello, Usana Luvira, Rollin Heinzerling, Raymond Romanski, Nathan W. Levin, Thomas K. H. Burnham

Henry Ford Hospital Medical Journal

Seventy-three patients with systemic lupus erythematosus (SLE) nephritis were studied for up to eight years using sequential serologic and renal function tests and renal biopsies. Antinuclear antibody (ANA) patterns and titers were classified into two systems: nonparticulate and particulate. We found a close relationship between disease activity and changes in titers of the nonparticulate peripheral homogeneous system. These changes predicted imminent flare-up or immunosuppressive induced remission of nephritis. Patients with the thready ANA pattern (part of the particulate system) as the main pattern showed a predominant association with membranous glomerulopathy and better renal function than those without threads. The association …

Prediction Of Intellectual Deficits In Children With Acute Lymphocytic Leukemia, Paul Trautman, Candace Erickson, David Shaffer, Patricia O'Connor, Annaliese Sitarz, Antonio Correra, Irvin Sam Schonfeld

Publications and Research

Possible predictors of reported lower cognitive functioning in irradiated children with acute lymphoblastic leukemia (ALL) were investigated. Thirty-four subjects, 5-14 years old, with ALL in continuous complete remission and without evidence of current or past central nervous system disease, were examined 9-110 months after diagnosis, using standard measures of intelligence and academic achievement. Subjects with a history of post-irradiation somnolence syndrome were significantly older at diagnosis than nonsomnolent subjects. Intelligence (IQ) was found to be unrelated to history of somnolence syndrome. IQ and achievement were unrelated to age at irradiation, irradiation-examination interval, and radiation dosages. The strongest predictor of IQ …

Magnetic Resonance Imaging Of Oromandibular Limb Hypogenesis Syndrome (Olhs) : Type 1a Congenital Hypoglossia With Micrognathia, Edmond H. Henken

Loma Linda University Electronic Theses, Dissertations & Projects

An eighteen-year old female with Oromandibular Limb Hypogenesis Syndrome Type 1A was imaged with Magnetic Resonance in the sagittal, coronal, and transverse planes with the jaws closed. The intrinsic muscles of the tongue, genioglossus, geniohyoid, mylohyoid, medial and lateral pterygoid muscles were identified and compared with a control of the same age and sex. All the muscles in question were present. Combined with the intrinsic muscles of the tongue, the genioglossus were approximately one-half the size of the control in the sagittal plane. The geniohyoid of the OLHS subject was enlarged most probably due to the hyperactivity of the floor …

Volume 31, Issue 3, Canadian Medical Association

Canadian Journal of Surgery

The mission of CJS is to contribute to the effective continuing medical education of Canadian surgical specialists, using innovative techniques when feasible, and to provide surgeons with an effective vehicle for the dissemination of observations in the areas of clinical and basic science research.

Visit the journal website at http://canjsurg.ca/ for more.

Epidemic Non-A Non-B Hepatitis In Urban Karachi, Pakistan, R A Jr Smego, A A. Khaliq

Section of Gastroenterology

An outbreak of icteric non-A non-B (NANB) hepatitis occurred in a residential community of urban Karachi, Pakistan, from August 1986 through October 1986. Of the 114 cases reported from this community during the 1986 calendar year, a clustering of 85 cases was seen during the above period. Twenty-seven percent of 226 households and 9% of 1,250 individuals were affected. Five persons were hospitalized and 1 death occurred in a young pregnant woman. Cases occurred predominantly in the less than or equal to 29-year-old age group (72%), with a male:female ratio of 1.8:1. Thirty-four cases occurred singly within households, while in …

Ua12/2/1 Magazine, Wku Student Affairs

WKU Archives Records

Special magazine edition of the College Heights Herald.

• Poore, Chris. The Jovial Judge – District Court Judge Tom Lewis
• White, Douglas. Dealing with Death
• White, Douglas. Hospice Eases Death Crisis
• Albrecht, Dana. Friends Forever – short story

Vital Signs, April 1988, Boonshoft School Of Medicine

Vital Signs

A twelve page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, alumni profiles, class notes, and more.

Digest Of The Philadelphia College Of Osteopathic Medicine (Spring 1988), Philadelphia College Of Osteopathic Medicine

Digest

The Spring 1988 issue of the Digest of the Philadelphia College of Osteopathic Medicine includes the following articles:

• First Contact
• DO's in the Arts
• How We Do lt!
• Giving & Receiving
• Alumni Notes
• On Campus
• Class Acts
• In Memoriam
• Calendar

Vitamin D And Parotid Gland Function In The Rat, C. Peterfy, A. Tenenhouse, E. Yu

Edward Yu

1. We previously reported that parotid gland secretion is decreased in rats deprived of vitamin D (Glijer, Peterfy & Tenenhouse, 1985). In the present study we examine whether this effect is a direct result of the absence of vitamin D or due to the secondary systemic effects of vitamin D deficiency. 2. Offspring of rats maintained on a calcium-supplemented (1.2%), vitamin-D-deficient diet were weaned onto the same diet and examined after 8 weeks. Using this method it was possible to maintain serum calcium and parathyroid hormone concentrations within normal limits. Serum 25-hydroxyvitamin D (25(OH)D3) was not detectable, but 1,25-dihydroxyvitamin D …

Simple Capsule Pneumograph, Steve S. Kraman

Internal Medicine Faculty Patents

A capsule pneumograph includes an electret microphone connected to a capsule chestpiece attached to a sleeping subject. The output of the microphone is connected to the input of a recorder or monitor in order to provide a system for the detection of respiratory movements in subjects during polysomnographic sleep monitoring. A tube connecting the capsule chestpiece to the microphone functions as a low pass filter to pass only low frequency signals in the range of respiratory movements from the chestpiece to the microphone.

Volume 31, Issue 2, Canadian Medical Association

Canadian Journal of Surgery

The mission of CJS is to contribute to the effective continuing medical education of Canadian surgical specialists, using innovative techniques when feasible, and to provide surgeons with an effective vehicle for the dissemination of observations in the areas of clinical and basic science research.

Visit the journal website at http://canjsurg.ca/ for more.

Virginity And Celibacy As Health Issues, Mary Guinan

Public Health Faculty Publications

Sexual behavior is both a health issue and a moral issue. Hence public education on sexuality has traditionally come from two main sources, those individuals or groups concerned with health and those concerned with morals. In his book No Magic Bullet (Oxford University Press, 1985), Allan Brandt describes the tensions that developed between these groups over the control of sexually transmitted diseases in the United States early in this century. Both groups wanted to control sexual behavior, but for different reasons. Public health personnel wanted to change sexual behavior in order to control infection and disease, while moralists believed that …

Front Matter

Henry Ford Hospital Medical Journal

No abstract provided.

A Double-Blind Trial Of Protriptyline In The Treatment Of Sleep Apnea Syndrome, Edward J. Stepanski, William A. Conway, David K. Young, Frank J. Zorick, Robert M. Wittig, Thomas Roth

Henry Ford Hospital Medical Journal

Eight male subjects with sleep apnea syndrome were given placebo and protriptyline in a double-blind crossover design to evaluate the effects of protriptyline on respiration during sleep. Treatment with protriptyline produced significantly better oxygenation and significantly fewer arousals during sleep, but sleep staging was unchanged. The decreased number of respiratory events approached significance and was much greater in six of eight subjects. A rapid eye movement sleep-suppression explanation of the improvement in oxygenation is not supported. Alternative explanations of these findings are discussed.

Anticoagulant Therapy, Antithrombotic Therapy, Pulmonary Embolism, And The Henry Ford Hospital Perspective, Paul D. Stein

Henry Ford Hospital Medical Journal

No abstract provided.

Familial Childhood Sleep Apnea, Robert M. Wittig, Frank J. Zorick, Timothy A. Roehrs, Jeanne M. Sicklesteel, Thomas Roth

Henry Ford Hospital Medical Journal

We report four siblings who had polysomnographically documented sleep apnea. Two presented with the typical clinical picture of sleep apnea syndrome including daytime somnolence and snoring, had repetitive obstructive apneic episodes during sleep, and were effectively treated with upper airway surgery. The other two were asymptomatic and showed infrequent apneic episodes during sleep. This family illustrates the distinction between the sleep apnea syndrome and infrequent apneic episodes during sleep. The sleep apnea syndrome is associated with daytime symptomatology and requires treatment. The presence of apneic episodes during sleep in all four siblings has implications regarding the predisposing factors (eg, upper …

Sleep-Wake Complaints And Their Relation To Sleep Disturbance, De Ton, Frank J. Zorick, Timothy A. Roehrs, Robert M. Wittig, Jeanne M. Sicklesteel, Thomas Roth

Henry Ford Hospital Medical Journal

This report is a comparison of patients presenting with 1) an insomnia complaint diagnosed as no objective findings. 2) insomnia diagnosed as being associated with a psychiatric disorder, and 3) daytime sleepiness diagnosed as no objective findings. The sleep of patients with insomnia diagnosed as no objective findings is comparable to that of patients with daytime sleepiness diagnosed as no objective findings and is significantly better than that of patients with insomnia associated with a psychiatric disorder. Significant differences were found in sleep induction, sleep maintenance, and overall sleep efficiency. No major differences were found among any of the groups …

A Mathematical Model Of Lung Static Pressure-Volume Relationships: Comparison Of Clinically Derived Parameters Of Elasticity, William Benish, Peggy Harper, Joseph Ward, John Popovich Jr.

Henry Ford Hospital Medical Journal

We constructed a simple model of lung distensibility in which the relationship between pressure (P) and volume (V) is of the exponential form obtained empirically: V = a+ becP , where a, b, and c are constants, and e is the base of the natural logarithm. The model lung is idealized as a frictionless diaphragm moving in a cylinder. Diaphragm movement is impeded by a variable force (F). By assuming that the rate of change of F is proportional to the inverse of the distance of the diaphragm from a maximal distance, the pressure-volume relationship assumes the above exponential form. …