Reproductive and Urinary Physiology Commons^™

Magnesium is an essential nutrient that acts as a cofactor in numerous enzymatic reactions including energy metabolism, protein and nucleic acid biosynthesis. Its supplementation has shown to be advantageous in hypertension and treatment of angina. The intricate mechanistic aspects of excess dietary magnesium in testicular morphology and functions have been investigated, as the available information found insufficient. Adult male Wister strain rats were fed magnesium sulphate (MgSO4) with standard diet at diverse doses for one and two consecutive seminiferous cycles (13 and 26 days respectively). Significant increase in the activities of testicular Δ 5 3β - hydroxysteroid dehydrogenase and 17β …

Calcium is essential for functioning of different systems including male reproduction. However, it has also been reported as chemo-castrative agent. The study has been undertaken to elucidate the effect of excessive dietary calcium on male reproductive system in animals with possible action. Adult male healthy rats fed CaCl2 at different doses (0.5 g %, 1.0 g % and 1.5 g %) in diet for 13 and 26 days to investigate reproductive parameters as well as the markers of oxidative stress. Significant alteration was found (p<0.05) in testicular and accessory sex organs weight, epididymal sperm count, testicular steroidogenic enzyme (Δ5 3β-HSD …