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Full-Text Articles in Neurosciences
The Origins Of Inspiratory And Sigh Breathing Rhythms: Ion Channels, Bursting Mechanisms, And Synaptic Topologies Studied In Vitro And In Silico, Cameron J. Grover
The Origins Of Inspiratory And Sigh Breathing Rhythms: Ion Channels, Bursting Mechanisms, And Synaptic Topologies Studied In Vitro And In Silico, Cameron J. Grover
Dissertations, Theses, and Masters Projects
Breathing is the rhythmic motor behavior which maintains homeostasis by driving gas exchange between our blood and the atmosphere. This behavior is essential for life in all terrestrial mammals. This behavior involves two distinct but coupled rhythms: the inspiratory rhythm, the normal breathing rhythm that occurs on the order of seconds, and the sigh rhythm, which produces large amplitude breaths that occur on the order of minutes and maintain pulmonary function. The rhythm for both behaviors and their control originates in a specialized neuronal region of the ventral medulla called the preBötzinger complex (preBötC). While we know the anatomical region …