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Full-Text Articles in Medical Neurobiology

A Comparison Of Four Electrical Stimulation Types On Staphylococcus Aureus Growth In Vitro, Harold Merriman, Chris Hegyi, Cheryl Albright-Overton, John Carlos, Robert Putnam, Janet Mulcare Feb 2015

A Comparison Of Four Electrical Stimulation Types On Staphylococcus Aureus Growth In Vitro, Harold Merriman, Chris Hegyi, Cheryl Albright-Overton, John Carlos, Robert Putnam, Janet Mulcare

Harold L. Merriman

We evaluated the efficacy of common electrical stimulation (ES) types on bacterial growth in vitro using clinically relevant conditions. Four types of ES-continuous microamperage direct current (µADC), high-voltage pulsed current (HVPC), low-voltage monophasic milliamperage pulsed current (LVMmAPC), and low-voltage biphasic milliamperage pulsed current (LVBmAPC)-were each applied to a separate set of culture plates containing Staphylococcus aureus for 1 h at 37 °C on 3 consecutive days. After ES treatment, the zone of inhibition surrounding each electrode was measured. Zone of inhibition measurements showed a significant inhibitory effect for continuous µADC and HVPC (p < 0.05), but not for LVMmAPC and LVBmAPC. …


Antioxidant Enzyme Gene Transfer For Ischemic Diseases, Jian Wu Jan 2009

Antioxidant Enzyme Gene Transfer For Ischemic Diseases, Jian Wu

jian duan wu

1. Adv Drug Deliv Rev. 2009 Apr 28;61(4):351-63. Epub 2009 Feb 20. Antioxidant enzyme gene transfer for ischemic diseases. Wu J, Hecker JG, Chiamvimonvat N. Department of Internal Medicine, Transplant Research Program, University of California, Davis Medical Center, Sacramento, CA 95817, USA. jdwu@ucdavis.edu The balance of redox is pivotal for normal function and integrity of tissues. Ischemic insults occur as results of a variety of conditions, leading to an accumulation of reactive oxygen species (ROS) and an imbalanced redox status in the tissues. The oxidant stress may activate signaling mechanisms provoking more toxic events, and eventually cause tissue damage. Therefore, …