Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Law (2)
- Bioethics and Medical Ethics (1)
- Business (1)
- Business Law, Public Responsibility, and Ethics (1)
- Community Health and Preventive Medicine (1)
-
- Disability Law (1)
- Disability Studies (1)
- Diseases (1)
- Dispute Resolution and Arbitration (1)
- Family, Life Course, and Society (1)
- Genetic Structures (1)
- Genetics and Genomics (1)
- Health Law and Policy (1)
- Intellectual Property Law (1)
- Law and Gender (1)
- Law and Society (1)
- Life Sciences (1)
- Medical Biotechnology (1)
- Nervous System Diseases (1)
- Privacy Law (1)
- Public Health (1)
- Reproductive and Urinary Physiology (1)
- Science and Technology Law (1)
- Social and Behavioral Sciences (1)
- Sociology (1)
- Women's Health (1)
- Institution
- Keyword
-
- Access (1)
- Animals (1)
- Assisted reproductive technology (1)
- Base sequence (1)
- Bioethics (1)
-
- Central nervous system diseases (1)
- Complementary (1)
- Confidentiality (1)
- Control (1)
- Core binding factor alpha 2 subunit (1)
- Disability (1)
- Dna (1)
- Dna primers (1)
- Dna-binding proteins (1)
- Employers (1)
- Employment (1)
- Erythropoiesis (1)
- Female (1)
- Fetal death (1)
- Gene targeting (1)
- Genetics (1)
- Hematopoiesis (1)
- Hemorrhage (1)
- Human genome project (1)
- Humans (1)
- Inbred balb c (1)
- Inbred c57bl (1)
- Infertility (1)
- Information (1)
- Insurance (1)
- Publication
- Publication Type
Articles 1 - 3 of 3
Full-Text Articles in Medical Genetics
Social Issues Of Genome Innovation And Intellectual Property, Elaine Alma Draper
Social Issues Of Genome Innovation And Intellectual Property, Elaine Alma Draper
RISK: Health, Safety & Environment (1990-2002)
Dr. Draper's focus is the use of personal information derived from genome research. She identifies several potential problems, including access to and control of genetic information, employment discrimination and social stratification. She also recommends possible solutions.
Disruption Of The Cbfa2 Gene Causes Necrosis And Hemorrhaging In The Central Nervous System And Blocks Definitive Hematopoiesis., Qing Wang, Terryl Stacy, Michael M Binder, Miguel Marin-Padilla, Arlene H. Sharpe, Nancy A. Speck
Disruption Of The Cbfa2 Gene Causes Necrosis And Hemorrhaging In The Central Nervous System And Blocks Definitive Hematopoiesis., Qing Wang, Terryl Stacy, Michael M Binder, Miguel Marin-Padilla, Arlene H. Sharpe, Nancy A. Speck
Dartmouth Scholarship
The CBFA2 (AML1) gene encodes a DNA-binding subunit of the heterodimeric core-binding factor. The CBFA2 gene is disrupted by the (8;21), (3;21), and (12;21) chromosomal translocations associated with leukemias and myelodysplasias in humans. Mice lacking a CBF alpha 2 protein capable of binding DNA die between embryonic days 11.5 and 12.5 due to hemorrhaging in the central nervous system (CNS), at the nerve/CNS interfaces of cranial and spinal nerves, and in somitic/intersomitic regions along the presumptive spinal cord. Hemorrhaging is preceded by symmetric, bilateral necrosis in these regions. Definitive erythropoiesis and myelopoiesis do not occur in Cbfa2-deficient embryos, and disruption …
Choice, Conscience, And Context, Mary Crossley
Choice, Conscience, And Context, Mary Crossley
Articles
Building on Professor Michael H. Shapiro's critique of arguments that some uses of new reproductive technologies devalue and use persons inappropriately (which is part of a Symposium on New Reproductive Technologies), this work considers two specific practices that increasingly are becoming part of the new reproductive landscape: selective reduction of multiple pregnancy and prenatal genetic testing to enable selective abortion. Professor Shapiro does not directly address either practice, but each may raise troubling questions that sound suspiciously like the arguments that Professor Shapiro sought to discredit. The concerns that selective reduction and prenatal genetic screening raise, however, relate not to …