Skin and Connective Tissue Diseases Commons^™

Associations Among Acne Vulgaris And Western Diet, Kate Meredith Suda

Physician Assistant Scholarly Project Posters

Acne vulgaris is one of the most common dermatologic conditions, especially among the adolescent population.

The pathogenesis of acne is largely multifactorial, with heredity and hormones strongly contributing to one’s risk of developing the chronic inflammatory skin condition.

High prevalence rates of acne in the adolescent population cannot be attributed to heredity alone, but by the influence of Western diet (WD) that overstimulates insulin-like growth factors (IGFs).

The purpose of this scholarly project is to determine if there is an association between the presence of acne vulgaris and the consumption of WD, and if a physiological link between the high …

Associations Among Acne Vulgaris And Western Diet, Kate Meredith Suda

Physician Assistant Scholarly Project Papers

Acne vulgaris is one of the most common dermatologic conditions, especially among the adolescent population. The pathogenesis of acne is largely multifactorial, with heredity and hormones strongly contributing to one’s risk of developing the chronic inflammatory skin condition; it is related to excess sebum production by sebaceous glands, inflammation within comedones, and hyperproliferation of Propionibacterium acnes. High prevalence rates of acne in the adolescent population cannot be attributed to heredity alone, but by the influence of Western diet that overstimulates a key conductor of metabolism, the growth factor-sensitive kinase known as mTORC1. Many investigations show associations between acne and Western …

Treatment Options For Hidradenitis Suppurativa: Efficacy, Risks, Benefits, Katherine A. Hennager

Physician Assistant Scholarly Project Posters

Hidradenitis suppurativa is a chronic, recurrent follicular occlusion disease with painful, sometimes debilitating, cutaneous draining lesions and subcutaneous abscesses (DynaMed Plus, 2016). Hidradenitis suppurativa is understood to be a multifactorial disease that is hard to treat in some patients, especially those with a severe form of the disease. For this project, the efficacy of adalimumab for hidradenitis suppurativa was assessed and whether it is more beneficial than traditional treatments used. Adalimumab is a TNF-alpha inhibitor which belongs to the biologic DMARDs drug class. Kimball et al. (2012) found that at week 16 of their trial 3.9% of the placebo patients, …

Treatment Options For Hidradenitis Suppurativa: Efficacy, Risks, Benefits, Katherine A. Hennager

Physician Assistant Scholarly Project Papers

Hidradenitis suppurativa is a chronic, recurrent follicular occlusion disease with painful, sometimes debilitating, cutaneous draining lesions and subcutaneous abscesses (DynaMed Plus, 2016). Hidradenitis suppurativa is understood to be a multifactorial disease that is hard to treat in some patients, especially those with a severe form of the disease. For this project, the efficacy of adalimumab for hidradenitis suppurativa was assessed and whether it is more beneficial than traditional treatments used. Adalimumab is a TNF-alpha inhibitor which belongs to the biologic DMARDs drug class. Kimball et al. (2012) found that at week 16 of their trial 3.9% of the placebo patients, …