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Articles 1 - 9 of 9
Full-Text Articles in Immune System Diseases
Congenital Zika Virus Infection In Immunocompetent Mice Causes Postnatal Growth Impediment And Neurobehavioral Deficits, Amber M. Paul, Dhiraj Acharya, Biswas Neupane, E. Ashley Thompson, Gabriel Gonzalez-Fernandez, Katherine M. Copeland
Congenital Zika Virus Infection In Immunocompetent Mice Causes Postnatal Growth Impediment And Neurobehavioral Deficits, Amber M. Paul, Dhiraj Acharya, Biswas Neupane, E. Ashley Thompson, Gabriel Gonzalez-Fernandez, Katherine M. Copeland
Publications
A small percentage of babies born to Zika virus (ZIKV)-infected mothers' manifest severe defects at birth, including microcephaly. Among those who appeared healthy at birth, there are increasing reports of postnatal growth or developmental defects. However, the impact of congenital ZIKV infection in postnatal development is poorly understood. Here, we report that a mild congenital ZIKV-infection in pups born to immunocompetent pregnant mice did not display apparent defects at birth, but manifested postnatal growth impediments and neurobehavioral deficits, which include reduced locomotor and cognitive deficits that persisted into adulthood. We found that the brains of these pups were smaller, had …
Calnexin Is Necessary For T Cell Transmigration Into The Central Nervous System, Amber M. Paul, Joanna Jung, Paul Eggleton, Alison Robinson, Jessica Wang, Nick Gutowski
Calnexin Is Necessary For T Cell Transmigration Into The Central Nervous System, Amber M. Paul, Joanna Jung, Paul Eggleton, Alison Robinson, Jessica Wang, Nick Gutowski
Publications
In multiple sclerosis (MS), a demyelinating inflammatory disease of the CNS, and its animal model (experimental autoimmune encephalomyelitis; EAE), circulating immune cells gain access to the CNS across the blood-brain barrier to cause inflammation, myelin destruction, and neuronal damage. Here, we discovered that calnexin, an ER chaperone, is highly abundant in human brain endothelial cells of MS patients. Conversely, mice lacking calnexin exhibited resistance to EAE induction, no evidence of immune cell infiltration into the CNS, and no induction of inflammation markers within the CNS. Furthermore, calnexin deficiency in mice did not alter the development or function of the immune …
Celibacy, Sexual Exclusivity, And Illicit Drug Abstinence: Giving Up The Life As Taboo In Aids Prevention, Ibpp Editor
Celibacy, Sexual Exclusivity, And Illicit Drug Abstinence: Giving Up The Life As Taboo In Aids Prevention, Ibpp Editor
International Bulletin of Political Psychology
This article highlights social cognitions that seem to impede cost-effective approaches to AIDS prevention.
Trends. The Privileged Status Of The Physical In Health Ideology: The Security Consequences Of Aids, Ibpp Editor
Trends. The Privileged Status Of The Physical In Health Ideology: The Security Consequences Of Aids, Ibpp Editor
International Bulletin of Political Psychology
The author discusses the importance of recognizing both physical and psychological factors of the AIDS (Acquired Immune Deficiency Syndrome) pandemic on security.
Psychological Summary Of The Aids Pandemic, Ibpp Editor
Psychological Summary Of The Aids Pandemic, Ibpp Editor
International Bulletin of Political Psychology
This article describes many of the psychological aspects related to identifying and responding to the Acquired Immune Deficiency Syndrome (AIDS) pandemic.
Trends. The Attack On Mbeki: Praising Through Damning, Ibpp Editor
Trends. The Attack On Mbeki: Praising Through Damning, Ibpp Editor
International Bulletin of Political Psychology
This article discusses the controversial contention by President Thabo Mbeki of the Republic of South Africa that poverty and lack of health infrastructures are the causes of AIDS and HIV in Africa instead of limiting his analysis to the biological line of virus inducing disease.
The Import Of Political Psychology For Global Health And Security: The Case Of Aids, Ibpp Editor
The Import Of Political Psychology For Global Health And Security: The Case Of Aids, Ibpp Editor
International Bulletin of Political Psychology
This article describes a number of applied research areas that political psychologists can explore to help manage the threat to global health and security from acquired immune deficiency syndrome (AIDS).
Trends. Controlling Aids Through Control, Ibpp Editor
Trends. Controlling Aids Through Control, Ibpp Editor
International Bulletin of Political Psychology
This article discusses the concept of political control and public health in the context of the HIV/AIDS epidemic.
Heterosexuality, Condoms, And Political Destabilization In Africa, Ibpp Editor
Heterosexuality, Condoms, And Political Destabilization In Africa, Ibpp Editor
International Bulletin of Political Psychology
This article describes psychosocial factors linked to condom use and the political implications of not maintaining this linkage.