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Articles 1 - 5 of 5
Full-Text Articles in Bacterial Infections and Mycoses
Clostridioides Difficile Infection Rates And Diabetes Mellitus In The Acute Care Hospital Setting: A Pilot Retrospective Study, Abigail Howe
Clostridioides Difficile Infection Rates And Diabetes Mellitus In The Acute Care Hospital Setting: A Pilot Retrospective Study, Abigail Howe
Honors College
Clostridioides difficile infections (CDI) are bacterial infections severely affecting an individual’s health and financially affecting health care settings. These infections are a persistent health care issue despite implementation of preventative measures. Research on the risk of acquiring CDI for individuals with comorbidities is scarce. Diabetes mellitus (DM) may negatively impact an individual’s immune system and consequently increase the risk of CDI. The purpose of this pilot study was to determine if the incidence of DM differed between patients who had CDI and patients who did not have CDI. After receiving an Internal Review Board (IRB) exempt status, electronic medical records …
Prevalence Of The Hypervirulent Nap1/Bi/027 Strain Of C. Difficile In Southwestern Virginia And Risk Factors Associated With Infection, Andrew O. Hanna, Anthony Baffoe-Bonnie, Shikha Vasudeva
Prevalence Of The Hypervirulent Nap1/Bi/027 Strain Of C. Difficile In Southwestern Virginia And Risk Factors Associated With Infection, Andrew O. Hanna, Anthony Baffoe-Bonnie, Shikha Vasudeva
Graduate Medical Education (GME) Resident and Fellow Research Day Posters
C. difficile infection (CDI) incidence has increased over the last several decades. The BI/NAP1/027 ribotype was discovered in 2005 and has since been responsible for multiple outbreaks in the US and Canada. This subtype of C. Difficile is known to be more virulent in vivo and produce more severe disease. Limited regional data of the prevalence of this ribotype is available, which could help guide treatment. Using infection control data from a large regional hospital and a VA medical center, this study documented the prevalence of the 027 ribotype in Southwest Virginia. Patients were included if they were tested at …
Probiotics And The Prevention Of Clostridioides Difficile: A Review Of Existing Systematic Reviews, Andrea L. Onstad
Probiotics And The Prevention Of Clostridioides Difficile: A Review Of Existing Systematic Reviews, Andrea L. Onstad
All Graduate Theses, Dissertations, and Other Capstone Projects
Clostridioides difficile is the leading cause of infectious diarrhea (Vernaya et al., 2017). Probiotics have been proposed to provide a protective benefit against Clostridioides difficile infection (CDI). The objective of this literature review was to examine the research evidence pertaining to the use of probiotics for the prevention of CDI in individuals receiving antibiotic therapy. A systematic literature review of studies published between 2015 and 2019 was performed. Five databases were searched, which yielded 10 systematic reviews that met strict inclusion criteria. Overall, the majority of evidence indicated that probiotics versus no treatment, placebo, or usual care have the potential …
There Is A Trend Favoring Vancomycin Vs. Metronidazole In Treating Severe C. Difficile Infection, Dean D. Fouchia
There Is A Trend Favoring Vancomycin Vs. Metronidazole In Treating Severe C. Difficile Infection, Dean D. Fouchia
Clinical Research in Practice: The Journal of Team Hippocrates
A critical appraisal and clinical application of Johnson S, Louie TJ, Gerding DN, et al. Vancomycin, metronidazole, or tolevamer for Clostridium difficile infection: results from two multinational, randomized, controlled trials. Clin Infect Dis. 2014;59(3):345-354. doi: 10.1093/cid/ciu313
Clostridium Difficile Associated Disease (Cdad), Rivka H. Borger
Clostridium Difficile Associated Disease (Cdad), Rivka H. Borger
The Science Journal of the Lander College of Arts and Sciences
Clostridium difficile bacteria (C. difficile) are a spore-forming species of bacteria that lies dormant in the colon, in the presence of normal intestinal flora. Due to overuse of certain antibiotics, normal intestinal bacteria may be depleted, and combined with other possible risk factors, allow C. difficile bacterial spores to develop into active, infectious, and extremely resistant toxin-producing bacteria. The toxins cause severe damage and inflammation to the intestinal wall that can result in gastrointestinal discomfort and severe pseudomembranous enterocolitis that must be treated with a low-risk C. difficile targeting defense.