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Clostridioides Difficile Infection Rates And Diabetes Mellitus In The Acute Care Hospital Setting: A Pilot Retrospective Study, Abigail Howe
Clostridioides Difficile Infection Rates And Diabetes Mellitus In The Acute Care Hospital Setting: A Pilot Retrospective Study, Abigail Howe
Honors College
Clostridioides difficile infections (CDI) are bacterial infections severely affecting an individual’s health and financially affecting health care settings. These infections are a persistent health care issue despite implementation of preventative measures. Research on the risk of acquiring CDI for individuals with comorbidities is scarce. Diabetes mellitus (DM) may negatively impact an individual’s immune system and consequently increase the risk of CDI. The purpose of this pilot study was to determine if the incidence of DM differed between patients who had CDI and patients who did not have CDI. After receiving an Internal Review Board (IRB) exempt status, electronic medical records …
Probiotics And The Prevention Of Clostridioides Difficile: A Review Of Existing Systematic Reviews, Andrea L. Onstad
Probiotics And The Prevention Of Clostridioides Difficile: A Review Of Existing Systematic Reviews, Andrea L. Onstad
All Graduate Theses, Dissertations, and Other Capstone Projects
Clostridioides difficile is the leading cause of infectious diarrhea (Vernaya et al., 2017). Probiotics have been proposed to provide a protective benefit against Clostridioides difficile infection (CDI). The objective of this literature review was to examine the research evidence pertaining to the use of probiotics for the prevention of CDI in individuals receiving antibiotic therapy. A systematic literature review of studies published between 2015 and 2019 was performed. Five databases were searched, which yielded 10 systematic reviews that met strict inclusion criteria. Overall, the majority of evidence indicated that probiotics versus no treatment, placebo, or usual care have the potential …