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Articles 1 - 4 of 4
Full-Text Articles in Other Chemicals and Drugs
Making The Case For Psychedelics: Comparing Alternative Treatment Options For Depression, Nicole Amavisca
Making The Case For Psychedelics: Comparing Alternative Treatment Options For Depression, Nicole Amavisca
Undergraduate Honors Theses
Given the number of people who are treated for depression each year and the knowledge that treatments work differently for everyone, there is a pressing need to provide a variety of treatment options. Although psychedelic research had been halted for a few decades due to recreational abuse, there has been revived interest due to its therapeutic potential in the treatment of mood disorders and addiction. As an example, the hallucinogen ketamine has recently been approved as a treatment for depression, which has opened the door for broadening the discussion on psychedelic research. Although the research is limited, psilocybin mimics ketamine …
The Life-Saving Drug That No One Knows About: Naloxone Education And The Health Belief Model, Sarah Tilford
The Life-Saving Drug That No One Knows About: Naloxone Education And The Health Belief Model, Sarah Tilford
Undergraduate Honors Theses
Naloxone hydrochloride, popularly known by the brand name Narcan, is an emergency treatment used to reverse an overdose on opioid drugs. The CDC reports upwards of 26,000 individuals saved by naloxone between 1996 and 2014 (Centers for Disease Control and Prevention, 2015). Despite this success rate, those outside of the medical field largely remain unaware of what naloxone is or how they can use it in an emergency, leading to needless loss of life. Many studies focusing on naloxone access and education have been unable to offer findings meant to increase the use and ownership of the drug by lay …
The Effects Of Chronic Alcohol Consumption On Ovarian Function/ Morphology, Destiny Roberts
The Effects Of Chronic Alcohol Consumption On Ovarian Function/ Morphology, Destiny Roberts
Undergraduate Honors Theses
Chronic alcohol (ethanol) consumption has been known to affect the major organs of the body and particularly the liver. However, the effects of chronic ethanol consumption on the female reproductive system remain relatively unstudied. A convenient way to study these effects is by analyzing laboratory mice that have been fed an ethanol diet for an extended period of time and comparing them to control mice. In this study, female mice were separated into control and ethanol fed groups. The mice were placed on their specified diets and observed over the course of six weeks. The mice were fed and weighed …
A Systematic Column Performance Comparison For The Confirmation Of Opioids Used In Pain Management By Lc-Ms, Derek Stallard
A Systematic Column Performance Comparison For The Confirmation Of Opioids Used In Pain Management By Lc-Ms, Derek Stallard
Undergraduate Honors Theses
In this study, three different chromatographic column chemistries (C18, Pentafluorophenyl (PFP), Hydrophilic Interaction Chromatography (HILIC)) were compared under optimal conditions to determine which stationary performed best in the separation and detection of a mixture of opioids using LC-MS. Furthermore, these stationary phases were examined in three different column technologies – traditional silica, porous shell, and porous polymer (PRP). The PRP column had the best peak shape for all 13 opioids and dominated for later-eluting compounds. In terms of column reproducibility, the Hamilton C18 column had the lowest %RSD values. The Kinetex HILIC produced the most theoretical plates and best resolution …