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Full-Text Articles in Medicine and Health Sciences

Gaza's Healthcare System In Collapse: An Exploratory Analysis Of Healthcare Attacks In Occupied Palestinian Territories (Opts) And Israel Since October 2023, Vincenzo J. Cornacchione Apr 2024

Gaza's Healthcare System In Collapse: An Exploratory Analysis Of Healthcare Attacks In Occupied Palestinian Territories (Opts) And Israel Since October 2023, Vincenzo J. Cornacchione

OHSU-PSU School of Public Health Annual Conference

Decades of apartheid practices and oppression in Occupied Palestinian Territories (OPTs), marked by mass displacement, restricted access to essential services, and countless human rights violations, have culminated in today's systematic dismantling of Gaza’s healthcare infrastructure. To investigate the systematic obstruction of healthcare access in OPT, this exploratory analysis employs an open intelligence dataset containing event data on reported healthcare attack incidents in OPT and Israel since October 2023. Specifically, this analysis seeks to elucidate the nature and extent of healthcare attacks in OPT by answering student-defined research questions, based on a priori expectations around the data. The analysis confirms that …


Impact Of Two Shift Schedules On Post-Shift Blood Pressure In Firefighters, Ayeisha H. Haswarey Apr 2024

Impact Of Two Shift Schedules On Post-Shift Blood Pressure In Firefighters, Ayeisha H. Haswarey

OHSU-PSU School of Public Health Annual Conference

Background: Firefighters have an increased risk of cardiometabolic disease compared to the general population. Blunted blood pressure (BP) dipping during nocturnal sleep is associated with increased cardiometabolic disease morbidity/mortality. Shift work can alter diurnal BP oscillation, but the extent of alteration by different schedules remains debated. No study to date has examined firefighting shift schedules, necessitating a longitudinal evaluation to begin to understand their implications for cardiometabolic health. Thus, this preliminary analysis compares how two common schedules (24/48 hours on/off vs. 1/3/2/3 days on/off) impact post-shift BP and dipping in 20 firefighters.

Methods: 20 participants (10% female; 25-54 years of …


Transgender And Non-Binary Health In Oregon Under A Single-Payer Health System, Amy (Mick) L. Mcveety (They/She) Apr 2024

Transgender And Non-Binary Health In Oregon Under A Single-Payer Health System, Amy (Mick) L. Mcveety (They/She)

OHSU-PSU School of Public Health Annual Conference

As the state with the highest percentage of population who identifies as LGBTQ+, Oregon has a duty to provide adequate health protections and services to its transgender and nonbinary (TGNB) residents, particularly given the disparities TGNB individuals face in housing, employment, education, and health. Following recommendations from the Oregon Joint Task Force on Universal Health Care, Oregon should implement a single-payer health care system, with particular attention to:

  1. Protecting patient privacy in EHR and other systems, particularly for youth TGNB patients;
  2. Expanding the covered gender-affirming services and removing barriers such as cost-sharing and prior authorization, and;
  3. Recruiting TGNB providers and …


Gender Affirming Surgery And Pain In Adolescents: Teen And Parent Experiences, Corrin Murphy, Eleanor Battison, University Of Rhode Island, Anna Wilson Phd Apr 2024

Gender Affirming Surgery And Pain In Adolescents: Teen And Parent Experiences, Corrin Murphy, Eleanor Battison, University Of Rhode Island, Anna Wilson Phd

OHSU-PSU School of Public Health Annual Conference

Background: Adolescents seeking gender affirming medical care face unique biopsychosocial challenges, including experiences of discrimination and stigma. Transgender and gender diverse (TGD) adolescents often undergo gender affirming surgery (GAS). While there is an increase in GAS for TGD adolescents in the U.S., little is known about the pain experiences in the post-surgical period among these youth. There have been no studies to our knowledge that examine the psychological functioning of parents and their ability to handle their child's distress, which may be affected by their child's post-GAS pain experiences. Parental responses to their children’s pain and distress may, in turn, …


Exploring Decolonial And Indigenous Mental Health Framework And Practice To Address Complex Trauma Among Palestinian Youth Living Under Violence Of Settler-Colonialism, Vivian L. Duong, Corrin Murphy Apr 2024

Exploring Decolonial And Indigenous Mental Health Framework And Practice To Address Complex Trauma Among Palestinian Youth Living Under Violence Of Settler-Colonialism, Vivian L. Duong, Corrin Murphy

OHSU-PSU School of Public Health Annual Conference

The growing settler colonial project of Israel forced indigenous Palestinians to flee from their homeland to further the Zionist movement of establishing a Jewish-majority state. The forced dispossession and displacement of Palestinians at this time was referred to as the Nakba, or catastrophe (Masalha, 2002). From 1947 and 1949, approximately 750,000 Palestinians from a population of 1.9 million were made refugees (Al Jazeera, 2017). Also referred to as the ethnic cleansing of Palestine, Zionists forcibly took over 78 percent of Palestine, destroyed about 530 villages and cities, and killed around 15,000 Palestinians including more than 70 massacres (Al Jazeera, 2017). …


Inequities In Chronic Stress Exposure At The Intersection Of Race, Gender, And Sexual Identity In A Nationally Representative Sample Of U.S. Adults, Jordan M. Lancaster, Efrain H. Chavez Martinez Apr 2024

Inequities In Chronic Stress Exposure At The Intersection Of Race, Gender, And Sexual Identity In A Nationally Representative Sample Of U.S. Adults, Jordan M. Lancaster, Efrain H. Chavez Martinez

OHSU-PSU School of Public Health Annual Conference

Background

Social inequity rooted in systemic oppression is robustly associated with mental and physical health; chronic stress is highlighted as a key mechanism. Limited research examining the association between sexual identity alone and C-reactive protein (CRP) – an upstream biological marker of chronic stress exposure – has yielded mixed results.

Purpose

To examine whether race/ethnicity, gender, and sexual identity interact to produce unequal levels of CRP.

Methods

Using cross-sectional data from the 2003-2010 waves of the National Health and Nutrition Examination Survey, we examined intersectional (self-reported race*gender*sexual identity) patterns in log-transformed CRP levels using a multivariable linear model among 10,885 …


Strong Hearts Program: The Results Of A Novel Primary-Care Based Diagnostic And Referral Program For Chagas Disease In East Boston, Ma, Usa, Javier J. Huerta Apr 2024

Strong Hearts Program: The Results Of A Novel Primary-Care Based Diagnostic And Referral Program For Chagas Disease In East Boston, Ma, Usa, Javier J. Huerta

OHSU-PSU School of Public Health Annual Conference

Purpose: Chagas disease (CD), a neglected parasitic infection, affects ~300,000 people in the US. Untreated, CD leads to irreversible cardiac morbidity and death in 20-30% of cases, yet

Methods: After provider and community sessions, 14,354 patients were screened at EBNHC from March 2017 - May 2023, following a prespecified protocol. Confirmed Chagas patients were referred to Boston Medical Center for further evaluation. Using chi-squared tests, we analyze diagnostic uptake and prevalence stratified by demographics. Additionally, we abstracted care continuum barriers from Chagas patients' records.

Results: Per quarter, a median of 572 patients were screened (IQR: 393 – 712). …


The Association Between Acculturation & C-Reactive Protein In U.S. Immigrants: A Cross-Sectional Study, Jessica Kilinski Bs, Rosol Mikail Bs, Kelly M. Reavis Phd, Mph, Deborah Karasek Phd, Mph Apr 2024

The Association Between Acculturation & C-Reactive Protein In U.S. Immigrants: A Cross-Sectional Study, Jessica Kilinski Bs, Rosol Mikail Bs, Kelly M. Reavis Phd, Mph, Deborah Karasek Phd, Mph

OHSU-PSU School of Public Health Annual Conference

Purpose: Immigrants undergo acculturation as they assimilate to a different culture, potentially leading to immense stress. Our objective was to examine the association between acculturation and C-reactive protein (CRP), a marker of stress-induced inflammation. We hypothesized that U.S. foreign-born adults 20 years and older with higher degrees of acculturation would have higher CRP levels compared to those with lower acculturation.

Method: We used 2017-2018 National Health and Nutrition Examination Survey (NHANES) data from 1526 participants to conduct a cross-sectional analysis. We measured acculturation as language spoken at home (categorized as low, moderate, and high) and examined its association with CRP …


The Use Of Extreme Risk Protection Orders Intended To Prevent Mass Violence In Oregon: A Descriptive Study, Rosol Mikail, Rebecca Valek, Shauna Rakshe, Rebecca Teichman, Susan Defrancesco, Kathleen Carlson Apr 2024

The Use Of Extreme Risk Protection Orders Intended To Prevent Mass Violence In Oregon: A Descriptive Study, Rosol Mikail, Rebecca Valek, Shauna Rakshe, Rebecca Teichman, Susan Defrancesco, Kathleen Carlson

OHSU-PSU School of Public Health Annual Conference

Purpose: Firearm violence is a critical public health issue in the United States. Extreme Risk Protection Order (ERPO) laws are an intervention method that have been enacted in many states to prevent firearm violence including mass violence threats. This study examined the characteristics of ERPO petitions filed in Oregon for a 6-year period that involved mass violence threats.

Method: ERPO petitions included in court records obtained through the Oregon Judicial Case Information Network, from January 1, 2018, to December 31, 2023 were abstracted; a 20% random sample of records was double-coded to ensure interrater reliability. An epidemiologic analysis of cases …


Impact Of Medical Formula Shortage On Patients With Inborn Errors Of Metabolism (Iem) And Their Dietitians, Haemin Lee Apr 2024

Impact Of Medical Formula Shortage On Patients With Inborn Errors Of Metabolism (Iem) And Their Dietitians, Haemin Lee

OHSU-PSU School of Public Health Annual Conference

Since Feb. of 2022, patients with inborn errors of metabolism (IEM) suffered medical formula shortages due to an abrupt shut down of a major formula company in the US. The goal of this project was to understand the nutritional and psychosocial impacts on patients with IEM and changes in patient-dietitian relations as a result of the unexpected formula shortage.

Two survey were set up and disseminated via REDCap to patients(18 years-old or older), parent/legal gurdian of patients in the US, from Dec.2023-Jan.2024. Of those 571 records, 139(60.4%) patient surveys and 166(48.7%) caregiver surveys were retained for analysis after dropping complete …


Supporting Self-Managed Abortion Care In “Practice Not Premise”: Provider Perspectives, Roles, And Referral Pathways In India, Laura E. Jacobson Mph, Caila Brander, P. Balasubramanian, Sruthi Chandrasekaran, Blair Darney, Julia Goodman, Ruvani Jayaweera, Caitlin Gerdts Apr 2024

Supporting Self-Managed Abortion Care In “Practice Not Premise”: Provider Perspectives, Roles, And Referral Pathways In India, Laura E. Jacobson Mph, Caila Brander, P. Balasubramanian, Sruthi Chandrasekaran, Blair Darney, Julia Goodman, Ruvani Jayaweera, Caitlin Gerdts

OHSU-PSU School of Public Health Annual Conference

Objective: Describe provider perspectives and roles in self-managed abortion (SMA) in India and identify referral pathways to facility- and self-managed abortion care.

Methods: We conducted a qualitative study of 33 semi-structured interviews with a range of providers (medical, community health, and pharmacy) in India. We conducted a thematic analysis and identified referral pathways including the type of provider, the abortion care modality (in-facility or SMA), and the reason.

Results: Referrals to facility-managed abortion care were common. Providers' perception of SMA safety coupled with­ liability concerns resulted in discouraging clients from seeking SMA. Nonetheless, participants acknowledged three areas where providers played …


Employer Voices: Insights On Bolstering Career Development For Graduate Students, Alexandria J. Ashraf Mph, Josh Hodsden Mba, Justin Howe Ba, Danielle Ross Ba, Dalton Wesemann Ba, Lisa K. Marriott Phd Apr 2024

Employer Voices: Insights On Bolstering Career Development For Graduate Students, Alexandria J. Ashraf Mph, Josh Hodsden Mba, Justin Howe Ba, Danielle Ross Ba, Dalton Wesemann Ba, Lisa K. Marriott Phd

OHSU-PSU School of Public Health Annual Conference

Title: Employer voices: Insights on Bolstering Career Development for Graduate Students

Alexandria J. Ashraf, MPH; Josh Hodsden, MBA, CPH; Justin Howe, BA; Danielle Ross, BA, CPH; Dalton Wesemann, BA; Lisa K. Marriott, PhD

Background: The development of the public health workforce has become increasingly vital as our world faces current and future challenges. The workforce has gained considerable insight into job skills that enhance responses to emergent needs. Building the foundation for a larger scale study on public health workforce needs, this project established processes for engaging with professionals who have hired recent public health graduates.

Methods: Open-ended questions assessed …


The Cost Of Healthy Eating, Diana Prychyna, Miriam R. Elman, Joy Kim, Karen F. Miller, Deonni P. Stolldorf, Sean P. Collins, Bory Kea Apr 2024

The Cost Of Healthy Eating, Diana Prychyna, Miriam R. Elman, Joy Kim, Karen F. Miller, Deonni P. Stolldorf, Sean P. Collins, Bory Kea

OHSU-PSU School of Public Health Annual Conference

Abstract

Background

Each year in the United States, 15-20% of 1 million visits to the Emergency Department for Acute Heart Failure result in home discharge, with patients often experiencing adverse health outcomes within 30 days. The study, Get With the Guidelines in Emergency Department Patients With Heart Failure (GUIDED-HF), utilized ‘Self-Care Coaches’ who meet participants via telehealth calls to discuss self-care maintenance after discharge as a strategy to mitigate adverse health outcomes; and offer provisions of resources, including a cookbook by the American Association for Heart Failure Nurses (AAHFN).

During the calls, we observed gaps in self-care for retired older …


“Sense Of Belonging”: Partnering With Central Oregon's Communities To Promote Health And Social Inclusion, Christina Jäderholm Apr 2024

“Sense Of Belonging”: Partnering With Central Oregon's Communities To Promote Health And Social Inclusion, Christina Jäderholm

OHSU-PSU School of Public Health Annual Conference

Abstract:

Community-engaged research can increase local research capacity and create momentum for social change. From research planning to dissemination, partnering with organizations and engaging with community members requires dedicated work and time. Using the Belonging project in Central Oregon as an example, we outline the ‘nuts and bolts’ of a community-engaged research process and highlight how we validated our findings through co-interpretation sessions.

Project

The Belonging project is a collaboration between Oregon Health & Science University (OHSU), Oregon State University - Cascades, the Central Oregon Health Council, and the Central Oregon communities. The project began [early] 2022 and concluded Feb …


Self-Reported Follow-Up Care Needs Can Be Met In Both Facility And Self-Managed Abortion: Evidence From Low- And Middle-Income Countries, Laura E. Jacobson Mph Apr 2024

Self-Reported Follow-Up Care Needs Can Be Met In Both Facility And Self-Managed Abortion: Evidence From Low- And Middle-Income Countries, Laura E. Jacobson Mph

OHSU-PSU School of Public Health Annual Conference

Objective: To understand in-facility follow-up care-seeking behavior among both people who self-managed medication abortions (SMA) and those who obtained facility-managed care in six countries and to explore factors that contribute to meeting individual’s self-reported care needs that are core to person-centered care.

Study Design: We conducted a qualitative thematic analysis of 67 in-depth interviews conducted with facility or SMA seekers. We first classified individuals as having their care needs met or not, and whether they sought follow-up care. We then identified predisposing, enabling, or need factors that contributed to having care needs met or not.

Results: A total of n=67 …


Using Systems Thinking Tools To Inform The Implementation Of A Cysticercosis Control Program In Rural Peru, Lisset M. Dumet Poma Mba, Angela Spencer Phd, Ruth Atto Bsc, Vanessa Cruz Bsc, Percy Vilchez Mph, Seth O'Neal Md, Mph For The Cysticercosis Working Group In Peru Apr 2024

Using Systems Thinking Tools To Inform The Implementation Of A Cysticercosis Control Program In Rural Peru, Lisset M. Dumet Poma Mba, Angela Spencer Phd, Ruth Atto Bsc, Vanessa Cruz Bsc, Percy Vilchez Mph, Seth O'Neal Md, Mph For The Cysticercosis Working Group In Peru

OHSU-PSU School of Public Health Annual Conference

Cysticercosis is an infectious disease responsible for 30-40% of acquired epilepsy in endemic areas such as rural Peru. Ring Treatment (RT) is a community-engaged cysticercosis control strategy, shown to be efficacious when delivered by research teams. We applied the Consolidated Framework for Implementation Research with additional constructs compatible with low-resource contexts in the formative evaluation to develop a protocol for implementing RT.

We included small, medium, and large municipal districts from northern Peru representing different rural primary health delivery settings. We collected 169 semi-structured and 341 network interviews. We applied Social-Network-Analysis to identify key players, roles, and collaborations to inform …


Trauma Informed Approaches To Researcher-Participant Relationships: Examples From A Housing And Health Study, Cristina Flores, Jade Garza, Judith R. Solomon, Marisa Westbrook Apr 2024

Trauma Informed Approaches To Researcher-Participant Relationships: Examples From A Housing And Health Study, Cristina Flores, Jade Garza, Judith R. Solomon, Marisa Westbrook

OHSU-PSU School of Public Health Annual Conference

In qualitative research, the aim of researcher-participant relationships is to allow for vulnerability and authenticity while maintaining professional boundaries. Trauma-informed care (TIC) in mental health services and social work considers the impact of violence and victimization in the lives of clients, while emphasizing trauma as causation (SAMHSA, 2014; Butler, 2011). Applying a trauma-informed approach to qualitative research processes may assist in building rapport with research participants, minimizing re-traumatization, appropriately interpreting results, and uncovering cultural significance. Research suggests that trauma-informed approaches avoid excluding underrepresented voices and allows researchers to engage through a social justice and health equity lens (Roche, 2020). For …


Chest Computed Tomography And Magnetic Resonance Imaging Texture Measurements Of Chronic Obstructive Pulmonary Disease, Maksym Sharma Apr 2024

Chest Computed Tomography And Magnetic Resonance Imaging Texture Measurements Of Chronic Obstructive Pulmonary Disease, Maksym Sharma

Electronic Thesis and Dissertation Repository

Pulmonary imaging using computed tomography (CT) and magnetic resonance imaging (MRI) provide a method to measure airway and parenchymal pathologic information that cannot be provided using spirometry. Currently, it remains difficult to predict which chronic obstructive pulmonary disease (COPD) patients will worsen using spirometry, which although safe and inexpensive, does not provide small airway information where COPD is believed to initiate. Quantitative CT and MRI measurements provide regional structure and function information but are not included in mortality risk assessments, prognosis, or COPD staging. Therefore, my overarching hypothesis is that CT and MRI ventilation texture measurements combined with machine learning …


Novel Tests For Motor And Spatial Deficits In Zebra Finches Verify A Role For Aromatase And Estradiol In Improving Spatial But Not Motor Outcomes Post-Cerebellar Lesion, Simran Patel, Lainy B. Day, Mathew Thibodeaux, Demetria Tolbert, Chyna-Rae Dearman, Gerald W. Stinson, Joshua Hamer, John C. Garner, Dwight Waddell Apr 2024

Novel Tests For Motor And Spatial Deficits In Zebra Finches Verify A Role For Aromatase And Estradiol In Improving Spatial But Not Motor Outcomes Post-Cerebellar Lesion, Simran Patel, Lainy B. Day, Mathew Thibodeaux, Demetria Tolbert, Chyna-Rae Dearman, Gerald W. Stinson, Joshua Hamer, John C. Garner, Dwight Waddell

Neuroscience Research Showcase

Objective: Test the role of Arom and E2 in recovery of zebra finch posture and spatial learning post-CB lesion.

Simran Patel1,2, Lainy B. Day1, Mathew Thibodeaux1, Demetria Tolbert1,2, Chyna-Rae Dearman1, Gerald W. Stinson1, Joshua Hamer1, John C. Garner3, Dwight Waddell 4 (1 Department of Biology, University of Mississippi, University MS; 2 Mississippi INBRE Research Scholar, University of Southern Mississippi, Hattiesburg MS; 3 Department of Kinesiology and Health Promotion, Troy University, Troy, AL 36082; 4 Department of Biomedical Engineering, University of Mississippi, University, MS …


Identifying The Distribution Of Peptide Hormones Regulating Adrenal And Gonadal Steroids In The Brains Of Diploid And Polypoid Treefrogs, Jordan Jackson, Chris J. Leary, Lainy B. Day Apr 2024

Identifying The Distribution Of Peptide Hormones Regulating Adrenal And Gonadal Steroids In The Brains Of Diploid And Polypoid Treefrogs, Jordan Jackson, Chris J. Leary, Lainy B. Day

Neuroscience Research Showcase

Hypothesis: polyploidization altered the relative expression levels of hormone receptors > altered regulation of circulating hormone levels and influence hormone interactions, or mutation of duplicated receptor coding genes. RNAseq - expression levels and sequences of receptors in the hypothalamic-pituitary-gonadal (HPG) and hypothalamic-pituitaryadrenal/ interrenal (HPA/I) axes

All authors are affiliated with the University of Mississippi Department of Biology.


Research Day 2024 Program, Western Michigan University Homer Stryker M.D. School Of Medicine Apr 2024

Research Day 2024 Program, Western Michigan University Homer Stryker M.D. School Of Medicine

Research Day

No abstract provided.


Evidence Based Practice Change To Incorporate A Standardized Process Checklist For Fecal Microbiota Therapy (Fmt) To Increase Staff Adherence, Alicia Gomez Apr 2024

Evidence Based Practice Change To Incorporate A Standardized Process Checklist For Fecal Microbiota Therapy (Fmt) To Increase Staff Adherence, Alicia Gomez

Student Scholarly Projects

Practice Problem: Staff adherence to new procedures is crucial for ensuring patient safety, maintaining quality care, reducing risks and liabilities, and fostering a positive organizational culture that supports continuous improvement. Having a procedure done safely for patients infected with C.diff provides an overall benefit to the healthcare system.

PICOT: In an endoscopy lab staffed with nurses and surgical technicians (P), does the implementation of a new standardized process of administering FDA approved Fecal Microbiota Transplant Therapy (I) compared to the current process (C), increase staff adherence to the process (O) over 12 weeks(T)?

Evidence: Leadership, supervision, and organizational culture are …


Project Prevent: A Randomized Controlled Trial Of Preoperative Vaginal Metronidazole To Decrease Patient Issues And Infections After Hysterectomy, Tana Pradhan, Helen Zhang, Amanda Kadesh, Ama Buskwofie, Sonali Patankar, Sharifa Menon, Timothy Ryntz, Cara Grimes Apr 2024

Project Prevent: A Randomized Controlled Trial Of Preoperative Vaginal Metronidazole To Decrease Patient Issues And Infections After Hysterectomy, Tana Pradhan, Helen Zhang, Amanda Kadesh, Ama Buskwofie, Sonali Patankar, Sharifa Menon, Timothy Ryntz, Cara Grimes

Abington Jefferson Health Papers

OBJECTIVES: To evaluate if vaginal metronidazole for 5 days before hysterectomy decreases postoperative infections and patient issues.

DESIGN: This randomized trial compared vaginal metronidazole for 5 days before a scheduled hysterectomy to no intervention. Sample size calculation was based on a 20% difference in issues and infection (30% incidence and 10% in the intervention arm) with 80% power and an alpha error of 0.05 and indicated 62 subjects needed in each arm.

SETTING: Outpatient gynecology clinics at a single academic institution.

PARTICIPANTS: 154 subjects were screened for eligibility between July 2020 and September 2022. 133 underwent hysterectomy including 68 subjects …


Graphic Medicine For Library Outreach, Chanda Briggs, Claire Sharifi Apr 2024

Graphic Medicine For Library Outreach, Chanda Briggs, Claire Sharifi

Gleeson Library Faculty and Staff Research and Scholarship

According to a National Academy of Sciences working group investigating the mental health crises in higher education, student wellbeing is an issue that needs to be addressed at the campus level, not siloed in specified departments and units. University libraries can be an integral part of student wellness initiatives, and this poster presentation will present one academic library’s engagement in student wellness initiatives. This poster will:

  • Highlight the ways campus partnerships facilitated streamlined library engagement in student wellness

  • Identify student centric initiatives and acquisitions

  • Identify funding sources used for those initiatives and acquisitions

  • Discuss outcomes of library wellness initiatives.


The Power Of Promotores: Enhancing The Ability Of Medical Students To Provide For And Communicate With Underserved Populations, Jesse Allen, Suzette Jimenez, Ricardo Belmares, Jose Manuel De La Rosa, Nathan A. Holland, Jessica Chacon Apr 2024

The Power Of Promotores: Enhancing The Ability Of Medical Students To Provide For And Communicate With Underserved Populations, Jesse Allen, Suzette Jimenez, Ricardo Belmares, Jose Manuel De La Rosa, Nathan A. Holland, Jessica Chacon

School of Medicine Publications and Presentations

To increase community health knowledge, the El Paso Health Education and Awareness Team (EP-HEAT) was established at Paul L. Foster School of Medicine. The Medical Student Run Clinic (MSRC) emphasizes community health care access. Promotores de salud (community health workers) increase health care awareness and connect predominantly underserved communities with resources. Surveys were conducted to determine how EP-HEAT and MSRC patients’ communication with promotores affected their access to health care and communication skills. Surveys demonstrated that 91% of EP-HEAT members agreed that working with promotores improved their communication ability. All MSRC patients surveyed stated interacting with promotores helped improve health …


Vista Checkpoint Inhibition By Ph-Selective Antibody Sns-101 With Optimized Safety And Pharmacokinetic Profiles Enhances Pd-1 Response, Thomas Thisted, Yoshiko Takeuchi, Robert D Schreiber, Et Al. Apr 2024

Vista Checkpoint Inhibition By Ph-Selective Antibody Sns-101 With Optimized Safety And Pharmacokinetic Profiles Enhances Pd-1 Response, Thomas Thisted, Yoshiko Takeuchi, Robert D Schreiber, Et Al.

2020-Current year OA Pubs

VISTA, an inhibitory myeloid-T-cell checkpoint, holds promise as a target for cancer immunotherapy. However, its effective targeting has been impeded by issues such as rapid clearance and cytokine release syndrome observed with previous VISTA antibodies. Here we demonstrate that SNS-101, a newly developed pH-selective VISTA antibody, addresses these challenges. Structural and biochemical analyses confirmed the pH-selectivity and unique epitope targeted by SNS-101. These properties confer favorable pharmacokinetic and safety profiles on SNS-101. In syngeneic tumor models utilizing human VISTA knock-in mice, SNS-101 shows in vivo efficacy when combined with a PD-1 inhibitor, modulates cytokine and chemokine signaling, and alters the …


Induction Of Viral Mimicry Upon Loss Of Dhx9 And Adar1 In Breast Cancer Cells, Kyle A Cottrell, Sua Ryu, Jackson R Pierce, Luisangely Soto Torres, Holly E Bohlin, Angela M Schab, Jason D Weber Apr 2024

Induction Of Viral Mimicry Upon Loss Of Dhx9 And Adar1 In Breast Cancer Cells, Kyle A Cottrell, Sua Ryu, Jackson R Pierce, Luisangely Soto Torres, Holly E Bohlin, Angela M Schab, Jason D Weber

2020-Current year OA Pubs

UNLABELLED: Detection of viral double-stranded RNA (dsRNA) is an important component of innate immunity. However, many endogenous RNAs containing double-stranded regions can be misrecognized and activate innate immunity. The IFN-inducible ADAR1-p150 suppresses dsRNA sensing, an essential function for adenosine deaminase acting on RNA 1 (ADAR1) in many cancers, including breast. Although ADAR1-p150 has been well established in this role, the functions of the constitutively expressed ADAR1-p110 isoform are less understood. We used proximity labeling to identify putative ADAR1-p110-interacting proteins in breast cancer cell lines. Of the proteins identified, the RNA helicase DHX9 was of particular interest. Knockdown of DHX9 in …


Participation And Outcomes Of A Community-Based Fall Prevention Program Before, During And After Covid-19 Pandemic., Bhavana Raja, Preeti Oza Apr 2024

Participation And Outcomes Of A Community-Based Fall Prevention Program Before, During And After Covid-19 Pandemic., Bhavana Raja, Preeti Oza

Pacific Journal of Health

Introduction: Several community education programs aim to minimize risk of falling in community-dwelling older adults. However, due to the covid-19 pandemic most of these programs stopped or were delivered virtually. A matter of balance (MOB) is one such program that was delivered virtually during pandemic. The purpose of this study is to assess the differences in outcomes between in-person and virtual MOB program in San Joaquin County of California.

Methods: Participants were recruited from the community. Each MOB course ran for 8 sessions in-person or 9 sessions in the virtual format. A retrospective analysis was conducted on deidentified pre-post survey …


Perceptions Of Emergency Physician Professionalism Among Healthcare Providers And Patients: A Multicenter Study In Thailand And The Us, Khuansiri Narajeenron Md, Mhpe, Tanawat Tarapan Md, Jasmina Dukovic, Krongkarn Sutham Md, Intanon Imsuwan Md, Ar-Aishah Dadeh Md, Tanyaporn Nakornchai Md, Deena Bengiamin Md, Bharath Chakravarthy Md, Mph, Craig Anderson Phd, Mph, Somchit Eiam-Ong Phd, Wirachin Hoonpongsimanont Md, Ms Apr 2024

Perceptions Of Emergency Physician Professionalism Among Healthcare Providers And Patients: A Multicenter Study In Thailand And The Us, Khuansiri Narajeenron Md, Mhpe, Tanawat Tarapan Md, Jasmina Dukovic, Krongkarn Sutham Md, Intanon Imsuwan Md, Ar-Aishah Dadeh Md, Tanyaporn Nakornchai Md, Deena Bengiamin Md, Bharath Chakravarthy Md, Mph, Craig Anderson Phd, Mph, Somchit Eiam-Ong Phd, Wirachin Hoonpongsimanont Md, Ms

Chulalongkorn Medical Journal

Background: Universal standards for emergency physician professionalism (EPP) amongst different groups of healthcare workers do not exist.

Objective: The aim of this study was to explore perceptions of EPP among attending physicians (APs), emergency medicine (EM) residents, first- and fourth-year medical students (MS1s and MS4s, respectively), EM nurses and emergency department (ED) patients.

Methods: A multicenter, cross-sectional study conducted at seven university-based EDs in Thailand and the US from July 2016 - January 2018. We created 39 cards (13 core elements) describing behaviors derived from a global literature review. Subjects ranked each card from the most to least important for …


Impact Of Preexisting Hypertension And Demographic Factors On Pandemic-Era Anxiety Using The Coronavirus Anxiety Scale, Chukwuemeka Ogbonnaya Okpom Apr 2024

Impact Of Preexisting Hypertension And Demographic Factors On Pandemic-Era Anxiety Using The Coronavirus Anxiety Scale, Chukwuemeka Ogbonnaya Okpom

Walden Dissertations and Doctoral Studies

No abstract provided.