Open Access. Powered by Scholars. Published by Universities.®

Toxicology Commons

Open Access. Powered by Scholars. Published by Universities.®

1993

Discipline
Institution
Keyword
Publication
Publication Type

Articles 1 - 9 of 9

Full-Text Articles in Toxicology

Validation Of A Bag Sampling Method For 1,3-Butadiene, Lori Eckenrode Dec 1993

Validation Of A Bag Sampling Method For 1,3-Butadiene, Lori Eckenrode

Community & Environmental Health Theses & Dissertations

At this time there is no NIOSH approved means for bag sampling 1,3-butadiene. An attempt was made to use the application of cold (0°F) to inhibit the reactivity of the gas prior to analysis. The State of California Air Resources Board has an approved method for the gas chromatographic analysis of 1,3-butadiene from stationary sources. The method was utilized in the application of industrial hygiene monitoring of affected workers. The application of cold was found to be ineffective at inhibiting the highly reactive nature of 1,3-butadiene. Analyte losses were too great to classify the method as an accurate measure of …


Pesticide Use On Broccoli, Cabbage, Cauliflower And Peppers Grown In Connecticut: 1991, James J. Turner Ii, Candace L. Bartholomew Aug 1993

Pesticide Use On Broccoli, Cabbage, Cauliflower And Peppers Grown In Connecticut: 1991, James J. Turner Ii, Candace L. Bartholomew

Storrs Agricultural Experiment Station

No abstract provided.


Pesticide Use On Peaches And Pears Grown In Connecticut: 1991, James L. Turner Ii, Candace L. Bartholomew Jun 1993

Pesticide Use On Peaches And Pears Grown In Connecticut: 1991, James L. Turner Ii, Candace L. Bartholomew

Storrs Agricultural Experiment Station

No abstract provided.


Interim Report On Data And Methods For Assessment Of 2,3,7,8-Tetrachlorodibenzo-P-Dioxin Risks To Aquatic Life And Associated Wildlife, Steven P. Bradbury, Philip M. Cook, Russell J. Erickson, Robert L. Spehar, Gerald T. Ankney Mar 1993

Interim Report On Data And Methods For Assessment Of 2,3,7,8-Tetrachlorodibenzo-P-Dioxin Risks To Aquatic Life And Associated Wildlife, Steven P. Bradbury, Philip M. Cook, Russell J. Erickson, Robert L. Spehar, Gerald T. Ankney

Steven P. Bradbury

In April, 1991 the Administrator of the U.S. Environmental Protection Agency (EPA) announced that the Agency would conduct a scientific reassessment of the risk of 2,3,7,8-tetrachlorodibenzo-p-dioxin (hereafter referred to as TCDD), and similar chemicals, to human health and the environment. Since 1985, EPA has classified TCDD, which it considers the most potent known animal carcinogen, as a probable human carcinogen. Sources of TCDD in the environment were subsequently regulated on the basis of animal cancer rates extrapolated to doses associated with human exposures. Recently, consensus has developed that the toxic effects of TCDD appear to be mediated by its binding …


El Envenenamiento De Aves Por Plomo: Un Grave Problema Que Sí Tiene Solución, Aldemaro Romero Jr. Jan 1993

El Envenenamiento De Aves Por Plomo: Un Grave Problema Que Sí Tiene Solución, Aldemaro Romero Jr.

Publications and Research

No abstract provided.


Toxicokinetics And Metabolism Of Aniline And 4-Chloroaniline In Medaka (Oryzias Latipes), Steven P. Bradbury, Julia M. Dady, Patrick N. Fitzsimmons, Michelle M. Voit, Dean E, Hammermeister, Russell J. Erickson Jan 1993

Toxicokinetics And Metabolism Of Aniline And 4-Chloroaniline In Medaka (Oryzias Latipes), Steven P. Bradbury, Julia M. Dady, Patrick N. Fitzsimmons, Michelle M. Voit, Dean E, Hammermeister, Russell J. Erickson

Steven P. Bradbury

The in vivo toxicokinetics and in vitro hepatic microsomal metabolism of (14C)aniline and (14C)4-chloroaniline in medaka (Oryzias latipes) were investigated to provide a basis upon which to interpret the toxicological responses of small aquarium fish to aniline derivatives. During static aqueous exposures of up to 320 min, parent equivalents failed to reach steady state and results from depuration studies clearly demonstrated biphasic elimination. Due to low elimination rates, 40 to 20% of absorbed aniline and 4-chloroaniline doses, respectively, remained within the fish through 330 min postexposure. Based on an analysis of excreted metabolites, N-acetylation was the dominant route of in …


A Non-Invasive Neurotoxicity Assay Using Larval Medaka, Steven P. Bradbury, Dave Featherstone, Charles D. Drewes, Joel R. Coats Jan 1993

A Non-Invasive Neurotoxicity Assay Using Larval Medaka, Steven P. Bradbury, Dave Featherstone, Charles D. Drewes, Joel R. Coats

Steven P. Bradbury

We present a method for non-invasive electrophysiological analysis of rapid escape responses in intact, freely behaving larval medaka (Oryzias latipes) before and after short-term exposure to environmental toxicants. Recordings are obtained as a larval medaka swims in a small chamber of water above pairs of recording electrodes etched onto a printed circuit board. When the chamber is briefly vibrated by a sinusoidal pulse from a speaker attached to the grid, a stereotyped Mauthner cell-initiated escape response is evoked. The following parameters were quantified from recordings: 1) Mauthner axon conduction velocity, 2) delay between Mauthner axon spike and motoneuron spike in …


Plomo: El Enemigo Invisible. La Contaminación Por Plomo En Venezuela, Aldemaro Romero Jr., Roberto Prato Ochoa Jan 1993

Plomo: El Enemigo Invisible. La Contaminación Por Plomo En Venezuela, Aldemaro Romero Jr., Roberto Prato Ochoa

Publications and Research

No abstract provided.


Characterization Of Anti-Tumor Immunity In Oyster Toadfish (Opsanus Tau), And The Effects Of 7,12 -Dimethylbenz(A)Anthracene On This Immune Response, Kenneth R. Seeley Jan 1993

Characterization Of Anti-Tumor Immunity In Oyster Toadfish (Opsanus Tau), And The Effects Of 7,12 -Dimethylbenz(A)Anthracene On This Immune Response, Kenneth R. Seeley

Dissertations, Theses, and Masters Projects

Cell-mediated lysis of cultured tumor target cells by nonspecific cytotoxic cells (NCC) was examined in the oyster toadfish (Opsanus tau), an estuarine teleost. NCC activity was evaluated in cells taken from the head kidney, peripheral blood, spleen and peritoneal cavity. NCC activity was a property of plastic nonadherent cells which lacked phagocytic activity, indicating that in terms of their functional capacity, the cells which mediate nonspecific cytoxic immune responses in oyster toadfish do not appear to be monocytes or macrophages. However, light and electron microscopic examination of these cells revealed that morphologically, they resemble monocytes and macrophages. A new technique …