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2004

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Articles 1 - 26 of 26

Full-Text Articles in Pharmacology

Layer-By-Layer Self -Assembly For Enzyme And Dna Encapsulation And Delivery, Amish Patel Oct 2004

Layer-By-Layer Self -Assembly For Enzyme And Dna Encapsulation And Delivery, Amish Patel

Doctoral Dissertations

Thin wall microcapsules were formed via Layer-by-Layer Self-Assembly of alternate adsorption of oppositely charged polyelectrolyte on microcores. After the core dissolution, empty polymeric shells with 20–25 nm thick walls were obtained. These microcapsules were loaded with Myoglobin, Hemoglobin and Glucose Oxidase by opening capsule pores at low pH and closing them at higher pH. The native structure of the enzyme was not affected due to different treatments. Biocompatible nanoshells were also prepared for encasing DNA. Using the same Layer-by-Layer Self-Assembly approach nanoparticle were constructed containing DNA as one of the layers. The nanoparticles of different architecture were used to deliver …


Effects Of Des-Aspartate-Angiotensin I On The Actions Of Angiotensin Iii In The Renal And Mesenteric Vasculature Of Normo-And Hypertensive Rats, Mohd Rais Mustafa, Murugan Dharmani, Kunheen N.K, Meng-Kwoon Sim Aug 2004

Effects Of Des-Aspartate-Angiotensin I On The Actions Of Angiotensin Iii In The Renal And Mesenteric Vasculature Of Normo-And Hypertensive Rats, Mohd Rais Mustafa, Murugan Dharmani, Kunheen N.K, Meng-Kwoon Sim

Mohd Rais Mustafa

An earlier study showed that des-aspartate-angiotensin I (DAA-I) attenuated the pressor action of angiotensin III in aortic rings of the spontaneously hypertensive rat (SHR) but not the normotensive Wistar Kyoto (WKY) rat. The present study investigated similar properties of DAA-I in isolated perfused kidneys and mesenteric beds of WKY and SHR. In the renal vasculature, angiotensin III induced a dosedependent pressor response, which was more marked in the SHR than WKY in terms of significant greater magnitude of response and lower threshold. DAA-I attenuated the pressor action of angiotensin III in both the WKY and SHR. The attenuation in SHR …


Regulatory Mechanisms Of Uterine Artery Contractility : Effect Of Pregnancy, Daliao Xiao Jun 2004

Regulatory Mechanisms Of Uterine Artery Contractility : Effect Of Pregnancy, Daliao Xiao

Loma Linda University Electronic Theses, Dissertations & Projects

Regulation of uterine blood flow during pregnancy is important not only for the growth and survival of the fetus but also for cardiovascular well-being of the mother. Pregnancy is associated with a significant decrease in uterine artery vascular tone and a dramatic increase in uterine blood flow. Previous studies have been focused on adaptation of the endothelium to pregnancy and indicated that increased NO sythesis/release plays an important role in vasodilation of the uterine artery in pregnancy. However, little is known about the adaptation of contractile mechanisms of the uterine artery to pregnancy. The central hypothesis of the proposed studies …


Hk-2 Cells As A Human Model Of Glucuronide Transport, Eliza E. Robertson Jan 2004

Hk-2 Cells As A Human Model Of Glucuronide Transport, Eliza E. Robertson

Theses, Dissertations and Capstones

Glucuronidation is primarily a pathway of detoxification in most species, but many glucuronide conjugates are associated with toxicity. Numerous drugs are excreted in the urine as glucuronide conjugates. Being organic anions, it is likely that glucuronides are secreted into the urine by organic anion transporters found in renal proximal tubule cells (PTCs). Some drugs that are metabolized by glucuronidation have been shown to cause renal toxicity, yet little is known about the renal handling of glucuronide conjugates. It is hypothesized that glucuronides are transported into renal PTCs by an organic anion transporter (OAT) on the basolateral membrane of the cell. …


Neuroscience Beyond 2005, ภาวิซ ทองโรจน์ Jan 2004

Neuroscience Beyond 2005, ภาวิซ ทองโรจน์

The Thai Journal of Pharmaceutical Sciences

No abstract provided.


Diseases, Drugs, And Brain Plasticity: Lessons Learned From The Study Of Headache, Anan Srikiatkhachorn Jan 2004

Diseases, Drugs, And Brain Plasticity: Lessons Learned From The Study Of Headache, Anan Srikiatkhachorn

The Thai Journal of Pharmaceutical Sciences

Plasticity of the nervous system is an important factor that determines the clinical presentation of several neurological conditions including headache and pain. In case of neuropathic pain, the sensitization and reorganization of neural circuitry involv...


Drugs And Brain Plasticity(ยาและความยืดหยุ่นของสมอง), Jintana Sattayasai Jan 2004

Drugs And Brain Plasticity(ยาและความยืดหยุ่นของสมอง), Jintana Sattayasai

The Thai Journal of Pharmaceutical Sciences

Brain plasticity is emerging as a fundamental and critical mechanism of neuronal function, which allows the brain to receive information and make the appropriate adaptive responses to subsequent related stimuli. The understanding of the mechanisms at mol...


งานวิจัยประสาทวิทยาศาสตร์ไนคณะเภสัชศาสตร์ จุฬาลงกรณ์มหาวิทยาลัย, มยุรี ตันติสิระ Jan 2004

งานวิจัยประสาทวิทยาศาสตร์ไนคณะเภสัชศาสตร์ จุฬาลงกรณ์มหาวิทยาลัย, มยุรี ตันติสิระ

The Thai Journal of Pharmaceutical Sciences

No abstract provided.


Development And Validation Of An Instrument To Assess The Attitudes Of Patients With Diabetes(การสร้างและทดสอบความตรงของเครื่องมือเพื่อใช้วัดทัศนคต..., Supakit Wongwiwatthananukit, Sarinee Krittiyanunt, Aunchalee Wannapinyo Jan 2004

Development And Validation Of An Instrument To Assess The Attitudes Of Patients With Diabetes(การสร้างและทดสอบความตรงของเครื่องมือเพื่อใช้วัดทัศนคต..., Supakit Wongwiwatthananukit, Sarinee Krittiyanunt, Aunchalee Wannapinyo

The Thai Journal of Pharmaceutical Sciences

The purpose of this methodological study was to develop a reliable and valid instrument to assess attitudes of patients with diabetes. This study was implemented through three major steps: (1) instrument development, (2) expert review of the instrument, ...


Development And Validation Of An Instrument To Assess The General Knowledge Of Patients With Diabetes(การสร้างและทดสอบความตรงของเครื่องมือเพื่อใช้วัดควา..., Supakit Wongwiwatthananukit, Sarinee Krittiyanunt, Aunchalee Wannapinyo Jan 2004

Development And Validation Of An Instrument To Assess The General Knowledge Of Patients With Diabetes(การสร้างและทดสอบความตรงของเครื่องมือเพื่อใช้วัดควา..., Supakit Wongwiwatthananukit, Sarinee Krittiyanunt, Aunchalee Wannapinyo

The Thai Journal of Pharmaceutical Sciences

The purpose of this methodological study was to develop a reliable and valid instrument to assess the general knowledge of diabetic patients. The study was implemented through three major steps: (1) instrument development, (2) expert review of the instru...


Knowledge Of Emergency Contraceptive Pills Among Undergraduate Students In Bangkok(ความรู้เกี่ยวกับยาเม็ดคุมกำเนิดฉุกเฉินในนักศึกษาระดับปริญ..., Khemin Aimnoi, Wirangrong Taeborisutikul, Wirote Chuenbunngam, Sasithon Ngaechareankul, Watcharee Lermankul Jan 2004

Knowledge Of Emergency Contraceptive Pills Among Undergraduate Students In Bangkok(ความรู้เกี่ยวกับยาเม็ดคุมกำเนิดฉุกเฉินในนักศึกษาระดับปริญ..., Khemin Aimnoi, Wirangrong Taeborisutikul, Wirote Chuenbunngam, Sasithon Ngaechareankul, Watcharee Lermankul

The Thai Journal of Pharmaceutical Sciences

The aim of this study was to ascertain the extent of knowledge and source(s) of information on emergency contraceptive (EC) pills among undergraduate students in Bangkok. The study was conducted in December 2003. Students from 10 of 37 possible institute...


Renal Effects Of Celecoxib And Naproxen In Elderly Patients(ผลต่อไตของยาซีลีคอกซิบและยานาพรอกเซนในผู้ป่วยสูงอายุ), Sungchai Angtharak, Sasiporn Dangthongdee, Wanchai Treyaprasert Jan 2004

Renal Effects Of Celecoxib And Naproxen In Elderly Patients(ผลต่อไตของยาซีลีคอกซิบและยานาพรอกเซนในผู้ป่วยสูงอายุ), Sungchai Angtharak, Sasiporn Dangthongdee, Wanchai Treyaprasert

The Thai Journal of Pharmaceutical Sciences

The purpose of this study was to compare renal effects between celecoxib and naproxen. The study was conducted in forty-eight elderly patients with musculoskeletal problems in Rheumatology Clinic at Rajavithi Hospital. Patients were treated with either n...


Modified Glutinous Starch As A Hydrophilic Matrix Substance(แป้งข้าวเหนียวดัดแปรเพื่อใช้เป็นสารเมทริกซ์ชนิดชอบน้ำ), Jomjai Peerapattana, Arom Tattawasart, Voranuch Srijesdaruk Jan 2004

Modified Glutinous Starch As A Hydrophilic Matrix Substance(แป้งข้าวเหนียวดัดแปรเพื่อใช้เป็นสารเมทริกซ์ชนิดชอบน้ำ), Jomjai Peerapattana, Arom Tattawasart, Voranuch Srijesdaruk

The Thai Journal of Pharmaceutical Sciences

The aim of this study is to modify the glutinous starch for hydrophilic matrix substance. Glutinous starch from glutinous rice was therm ally modified using single screw extruder at the tem peratures of 75, 75 and 80°c for zone 1, 2 and 3, respectively....


Antimutagenicity Of Different Lyophilized Ripe Bananas On Mutagens In Ames Test And Somatic Mutation And Recombination Test(ฤทธิ์ต้านสารก่อกลายพันธุ์ของผงกล้วยต่างชนิด..., Kalyarat Kruawan, Kaew Kangsadalampai, Komchanok Limpichaisopon Jan 2004

Antimutagenicity Of Different Lyophilized Ripe Bananas On Mutagens In Ames Test And Somatic Mutation And Recombination Test(ฤทธิ์ต้านสารก่อกลายพันธุ์ของผงกล้วยต่างชนิด..., Kalyarat Kruawan, Kaew Kangsadalampai, Komchanok Limpichaisopon

The Thai Journal of Pharmaceutical Sciences

The Ames test was employed to indicate the inhibitory effects of lyophilized powders prepared from three varieties of ripe bananas, namely, Klouy Nam Wa (Pisang Awak or Musa ABB group) Klouy Hom (Gros Michael or Musa AAA group), and Klouy Khai (Pisang Ma...


How Much Do We Pay For Medicines? A Drugstore Price Surveya Cross Thailand(ราคาขายของยา: การสำรวจราคายาจากร้านยาทั่วประเทศ), Puree Anantachoti, Chanpen Choompon, Boonsuchin Chatpitun, Rossukon Siwamutita Jan 2004

How Much Do We Pay For Medicines? A Drugstore Price Surveya Cross Thailand(ราคาขายของยา: การสำรวจราคายาจากร้านยาทั่วประเทศ), Puree Anantachoti, Chanpen Choompon, Boonsuchin Chatpitun, Rossukon Siwamutita

The Thai Journal of Pharmaceutical Sciences

Products and services that serve fundamental needs, including medicines, are normally price controlled. The Ministry of Commerce required that all drug prices be declared and monitored. However, most declared drug prices are much higher than actual price...


Antimicrobial Utilization In Nosocomial-Infected Patients At Ratchaburi Hospital(การใช้ยาต้านจุลชีพในผู้ป่วยโรคติดเชื้อในโรงพยาบาลที่โรงพย..., Sarinee Krittiyanunt, Wundee Khumyoung Jan 2004

Antimicrobial Utilization In Nosocomial-Infected Patients At Ratchaburi Hospital(การใช้ยาต้านจุลชีพในผู้ป่วยโรคติดเชื้อในโรงพยาบาลที่โรงพย..., Sarinee Krittiyanunt, Wundee Khumyoung

The Thai Journal of Pharmaceutical Sciences

The objectives of this descriptive study were to study the antimicrobial utilization, type and susceptibility of pathogens, and drug therapy problems (DTPs) in nosocomia-infected patients at Ratchaburi hospital from August 1st to December 31st, 2002. Two...


Effect Of Factors On Cell Culture Used In Potency Test Of Viral Vaccines(ป้จจัยที่มีผลต่อเซลล์เพาะเลี้ยงที่ใช้ในการตรวจสอบความแรงของว..., Supapom Phumiamom, Sakalin Trisiriwanich, Choompon Noktong, Komnika Kullabutr, Teeranart Jivapaisampong Jan 2004

Effect Of Factors On Cell Culture Used In Potency Test Of Viral Vaccines(ป้จจัยที่มีผลต่อเซลล์เพาะเลี้ยงที่ใช้ในการตรวจสอบความแรงของว..., Supapom Phumiamom, Sakalin Trisiriwanich, Choompon Noktong, Komnika Kullabutr, Teeranart Jivapaisampong

The Thai Journal of Pharmaceutical Sciences

(Factors which influence on potency assay of measles, rubella and polio vaccines were investigated by using Vero, RK-13 and Hep-2 cells, respectively. The result showed that cultures of Vero, RK-13 and Hep-2 cells in the presence of 5% CO2 produced 23 ti...


Predictors Of General Knowledge And Attitudes In Thai Diabetic Patients(ป้จจัยทำนายความรู้ทั่วไปและทัศนคติของผู้ป่วยเบาหวานคนไทย), Supakit Wongwiwatthananukit, Sarinee Krittiyanunt, Thongkum Sunthomthepvarakul, Aunchalee Wannapinyo Jan 2004

Predictors Of General Knowledge And Attitudes In Thai Diabetic Patients(ป้จจัยทำนายความรู้ทั่วไปและทัศนคติของผู้ป่วยเบาหวานคนไทย), Supakit Wongwiwatthananukit, Sarinee Krittiyanunt, Thongkum Sunthomthepvarakul, Aunchalee Wannapinyo

The Thai Journal of Pharmaceutical Sciences

The aim of this cross-sectional survey study was to determine the relationships between patients’ demographic characteristics and the level of knowledge and attitudes toward diabetes. A total of 811 diabetes patients participated and were assessed duri...


Key Word Index, Author Index(ดรรชนีกุญแจคำ,ดรรชนีผู้แต่ง), N/A Jan 2004

Key Word Index, Author Index(ดรรชนีกุญแจคำ,ดรรชนีผู้แต่ง), N/A

The Thai Journal of Pharmaceutical Sciences

No abstract provided.


Balancing Ease And Accuracy In Assessing Pharmaceutical Exclusion Payments, Mark D. Janis, Herbert Hovenkamp, Mark A. Lemley Jan 2004

Balancing Ease And Accuracy In Assessing Pharmaceutical Exclusion Payments, Mark D. Janis, Herbert Hovenkamp, Mark A. Lemley

Articles by Maurer Faculty

No abstract provided.


Author Index, N/A Jan 2004

Author Index, N/A

The Thai Journal of Pharmaceutical Sciences

No abstract provided.


Depressive Disorders And Brain Plasticity, Surachai Unchern Jan 2004

Depressive Disorders And Brain Plasticity, Surachai Unchern

The Thai Journal of Pharmaceutical Sciences

Previous hypotheses to explain the cause and treatment of depression have been based in part on the acute actions of antidepressants. However, the time lag for a therapeutic response has led to the hypothesis that adaptations to the acute actions of anti...


Mind, Brain, Body : Cognitive-Behavioral Therapy And Buddhist Concept(ร่างกาย สมอง และจิตใจ : ประซาน-พฤติกรรมบำบัดและแนวคิดเชิงพุทธ), Chamlong Disayavanish, Primprao Disayavanish Jan 2004

Mind, Brain, Body : Cognitive-Behavioral Therapy And Buddhist Concept(ร่างกาย สมอง และจิตใจ : ประซาน-พฤติกรรมบำบัดและแนวคิดเชิงพุทธ), Chamlong Disayavanish, Primprao Disayavanish

The Thai Journal of Pharmaceutical Sciences

Several studies have identified neural circuitry and signaling pathway of the brain that is involved in depression. Stress can cause cellular atrophy and suppress neurogenesis of neurons in the hippocampus resulting in the decrease of its volume. There i...


Effect Of New Synthetic Acyl Aniline And Acyl Aminopyridine Derivatives On Contractility Of Rat Aorta(ผลของสารสังเคราะห์ชนิดใหม่ในกลุ่มเอซิลอะนิลีน และเอ..., Amonrat Khayungarnnawee, Prasan Dhumma-Upakom, Chamnan Patarapanich, Suree Jianmongkol Jan 2004

Effect Of New Synthetic Acyl Aniline And Acyl Aminopyridine Derivatives On Contractility Of Rat Aorta(ผลของสารสังเคราะห์ชนิดใหม่ในกลุ่มเอซิลอะนิลีน และเอ..., Amonrat Khayungarnnawee, Prasan Dhumma-Upakom, Chamnan Patarapanich, Suree Jianmongkol

The Thai Journal of Pharmaceutical Sciences

A number of the synthetic acyl aniline derivatives and acyl aminopyridine derivatives were shown to influence contractility of the smooth muscle such as that of rat duodenum and aorta. Previous studies have shown that the effects of acyl-3-aniline deriva...


Pharmacist Compensation Survey In Thailand(การสำรวจค่าตอบแทนของเภสัชกรในประเทศไทย), Surachat Ngorsuraches, Banjong Chaibu Jan 2004

Pharmacist Compensation Survey In Thailand(การสำรวจค่าตอบแทนของเภสัชกรในประเทศไทย), Surachat Ngorsuraches, Banjong Chaibu

The Thai Journal of Pharmaceutical Sciences

The objective of this study was to survey pharmacist compensation in Thailand. The pharmacists’ compensation from both full-time and part-time works was examined. The study was cross-sectional descriptive design and data were collected by mailed survey...


Indole Alkaloids From The Fruits Of Alstonia Scholaris(อินโดลแอลคาลอยด์จากผลของพญาสัตบรรณ), Sumphan Wongseripipatana, Lakhana Chaisri, Boonchoo Sritularak, Kittisak Likhitwitayawuid Jan 2004

Indole Alkaloids From The Fruits Of Alstonia Scholaris(อินโดลแอลคาลอยด์จากผลของพญาสัตบรรณ), Sumphan Wongseripipatana, Lakhana Chaisri, Boonchoo Sritularak, Kittisak Likhitwitayawuid

The Thai Journal of Pharmaceutical Sciences

A MeOH extract prepared from the fruits of Alstonia scholaris, after acid-base treatment, gave a crude alkaloid extract which was then subjected to chromatographic separation to afford four indole alkaloids, namely 19-77-picrinine (l),19-A,-akuammidine (...