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Regulatory Mechanisms Of Uterine Artery Contractility : Effect Of Pregnancy, Daliao Xiao
Regulatory Mechanisms Of Uterine Artery Contractility : Effect Of Pregnancy, Daliao Xiao
Loma Linda University Electronic Theses, Dissertations & Projects
Regulation of uterine blood flow during pregnancy is important not only for the growth and survival of the fetus but also for cardiovascular well-being of the mother. Pregnancy is associated with a significant decrease in uterine artery vascular tone and a dramatic increase in uterine blood flow. Previous studies have been focused on adaptation of the endothelium to pregnancy and indicated that increased NO sythesis/release plays an important role in vasodilation of the uterine artery in pregnancy. However, little is known about the adaptation of contractile mechanisms of the uterine artery to pregnancy. The central hypothesis of the proposed studies …