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Full-Text Articles in Human and Clinical Nutrition
Zika Virus Induces Apoptosis In Retinal Pigmented Epithelial Cells, Madison Kraus, Philma Glora Muthuraj, Sathish Kumar Natarajan
Zika Virus Induces Apoptosis In Retinal Pigmented Epithelial Cells, Madison Kraus, Philma Glora Muthuraj, Sathish Kumar Natarajan
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Zika virus is a single-stranded positive sense RNA virus that attracted international attention in 2015 when an epidemic broke out in Brazil. This vector borne virus is transmitted by mosquitos and is especially concerning for pregnant women because the virus can affect the development of the fetus. One known complication is the destruction of infected retinal epithelial cells. The transduction of light is interrupted due to cell death and results in blind spots. Previous research has demonstrated that palmitoleate can reduce the observed levels of apoptosis in ZIKAV infected JEG-3 cells. We have also seen the protection of retinal pigmented …
3-Hydroxy Fatty Acid Induce Trophoblast And Hepatocyte Lipoapoptosis, Taylor Bruett, Taylor Heng, Sathish Kumar Natarajan
3-Hydroxy Fatty Acid Induce Trophoblast And Hepatocyte Lipoapoptosis, Taylor Bruett, Taylor Heng, Sathish Kumar Natarajan
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Acute Fatty Liver of Pregnancy (AFLP) is a very rare and fatal condition for both the mother and the unborn offspring accompanied by severe maternal liver dysfunction. AFLP usually develops during the third trimester of pregnancy with symptoms of liver disease. AFLP is associated with a mutation in the enzyme, long-chain 3-hydroxy acyl CoA dehydrogenase (LCHAD) which is involved in the mitochondrial beta-oxidation of fatty acids. Defective beta-oxidation of fatty acids results in the individual unable to metabolize fatty acids which then causes fatty infiltration in their organs, such as the liver. This interferes with normal function of the liver …
Relationship Between Body Composition, Fitness, And Eating Behaviors And Markers Of Metabolic Suppression In Exercising Men, Mikayla K. Locke, Karsten Koehler
Relationship Between Body Composition, Fitness, And Eating Behaviors And Markers Of Metabolic Suppression In Exercising Men, Mikayla K. Locke, Karsten Koehler
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Introduction: Chronic dieting can result in characteristic metabolic adaptations such as a suppression of resting metabolic rate (RMR). Previous research has focused on health outcomes related to metabolic suppression in female athletes, which include impaired menstrual and bone health. The study purpose was to assess the relationship between metabolic suppression and body composition, fitness, and eating behavior traits in exercising men.
Approach: Cross-sectional study comparing exercising men who display evidence of metabolic suppression (MS) and a control group (Con). RMR was used as a surrogate marker of metabolic suppression.
Results and Discussion: When compared to Con, MS …